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Volumn 133, Issue 5, 2011, Pages 1209-1211

Intramolecular oxidative C-H coupling for medium-ring synthesis

Author keywords

[No Author keywords available]

Indexed keywords

RING SYNTHESIS;

EID: 79551708034     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja1090854     Document Type: Article
Times cited : (154)

References (51)
  • 29
    • 34548018800 scopus 로고    scopus 로고
    • The benzodiazepine motif and related congeners are prominent examples of medium (seven)-ring systems in drug molecules. Aside from this class, seven-, eight-, and nine-membered-ring systems are rare in current marketed drugs. Review: Majhi, T. P.; Achari, B.; Chattopadhyay, P. Heterocycles 2007, 71, 1011-1052.
    • (2007) Heterocycles , vol.71 , pp. 1011-1052
    • Majhi, T.P.1    Achari, B.2    Chattopadhyay, P.3
  • 31
    • 79551698095 scopus 로고    scopus 로고
    • The reaction conditions were effective for six-membered-ring formation. The six-membered analogue of 2a was isolated in 87% yield using the same procedure (Supporting Information)
    • The reaction conditions were effective for six-membered-ring formation. The six-membered analogue of 2a was isolated in 87% yield using the same procedure (Supporting Information).
  • 41
    • 79551700002 scopus 로고    scopus 로고
    • We note that Gorelsky and co-workers13c have identified C-H bond length, rather thanC-Hacidity, as the governing influence inCMD mechanisms for the intermolecular arylation of arenes with aryl bromides
    • We note that Gorelsky and co-workers13c have identified C-H bond length, rather thanC-Hacidity, as the governing influence inCMD mechanisms for the intermolecular arylation of arenes with aryl bromides.
  • 45
    • 79551692807 scopus 로고    scopus 로고
    • Intermolecular KIEs between 2.0 and 2.5 were observed for 1g deuterated at the sites of indole and aryl C-H activation. See Supporting Information for details
    • Intermolecular KIEs between 2.0 and 2.5 were observed for 1g deuterated at the sites of indole and aryl C-H activation. See Supporting Information for details.
  • 50
    • 25444484716 scopus 로고    scopus 로고
    • For an elegant approach to related annulated indoles using norbornene shuttle chemistry, see: (a) Bressy, C.; Alberico, D.; Lautens, M. J. Am. Chem. Soc. 2005, 127, 13148-13149.
    • (2005) J. Am. Chem. Soc. , vol.127 , pp. 13148-13149
    • Bressy, C.1    Alberico, D.2    Lautens, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.