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Volumn 32, Issue 2, 2011, Pages 141-151

Active ingredients in Chinese medicines promoting blood circulation as Na+ /K+-ATPase inhibitors

Author keywords

blood circulation; cardiac glycoside; ginsenoside; magnesium lithospermate B; Na+ K+ ATPase inhibitors; neuroprotection; steroid like compound; traditional Chinese medicine

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM) INHIBITOR; ASTRAGALOSIDE III; BETA BOSWELLIC ACID; BETULIC ACID; BUFALIN; CARDIAC GLYCOSIDE; CHOLIC ACID; CUCURBITACIN GLYCOSIDE; DEHYDROCORYDALINE; DIGOXIN; GINSENOSIDE; GINSENOSIDE RH 2; GLYCYRRHIZIC ACID; HIRSUTINE; INOKOSTERONE; ISOLIMONOIC ACID; JUJUBOSIDE B; MAGNESIUM LITHOSPERMATE; OLEANOLIC ACID; OUABAIN; PACHYMIC ACID; POLYGALACIC ACID; RHYNCHOPHYLLINE; SAIKOSAPONIN A; SAPONIN; SARSASAPOGENIN; SITOSTEROL; STEROID; TRITERPENOID; UNCLASSIFIED DRUG; URSOLIC ACID;

EID: 79551656119     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2010.197     Document Type: Review
Times cited : (43)

References (100)
  • 1
    • 0141646512 scopus 로고    scopus 로고
    • Congestive heart failure and the elderly
    • Boxer R, Yang SX, Hager WD. Congestive heart failure and the elderly. Conn Med 2003; 67: 497-503.
    • (2003) Conn. Med. , vol.67 , pp. 497-503
    • Boxer, R.1    Yang, S.X.2    Hager, W.D.3
  • 2
    • 0022849823 scopus 로고
    • Cardiotoxicity of digitalis
    • Haustein KO. Cardiotoxicity of digitalis. Arch Toxicol Suppl 1986; 9: 197-204.
    • (1986) Arch. Toxicol. Suppl. , vol.9 , pp. 197-204
    • Haustein, K.O.1
  • 3
    • 0031933911 scopus 로고    scopus 로고
    • Toxic digoxin-drug interactions: The major role of renal P-glycoprotein
    • Koren G, Woodland C, Ito S. Toxic digoxin-drug interactions: the major role of renal P-glycoprotein. Vet Hum Toxicol 1998; 40: 45-6.
    • (1998) Vet. Hum. Toxicol. , vol.40 , pp. 45-46
    • Koren, G.1    Woodland, C.2    Ito, S.3
  • 5
    • 0036636969 scopus 로고    scopus 로고
    • Stroke therapy in traditional Chinese medicine TCM: Prospects for drug discovery and development
    • Gong X, Sucher NJ. Stroke therapy in traditional Chinese medicine (TCM): prospects for drug discovery and development. Phytomedicine 2002; 9: 478-84.
    • (2002) Phytomedicine , vol.9 , pp. 478-484
    • Gong, X.1    Sucher, N.J.2
  • 6
    • 24144469390 scopus 로고    scopus 로고
    • Clinical observation on influence of Chinese medicines for promoting blood circulation to remove blood stasis on FIB and DD in plasma of patients with cerebral thrombosis
    • Liang H, Chen S, Shen S. Clinical observation on influence of Chinese medicines for promoting blood circulation to remove blood stasis on FIB and DD in plasma of patients with cerebral thrombosis. J Tradit Chin Med 2002; 22: 256-9.
    • (2002) J. Tradit. Chin. Med. , vol.22 , pp. 256-259
    • Liang, H.1    Chen, S.2    Shen, S.3
  • 7
    • 60349129230 scopus 로고    scopus 로고
    • Phytochemical analysis of traditional Chinese medicine using liquid chromatography coupled with mass spectrometry
    • Yang M, Sun J, Lu Z, Chen G, Guan S, Liu X, et al. Phytochemical analysis of traditional Chinese medicine using liquid chromatography coupled with mass spectrometry. J Chromatogr A 2009; 1216: 2045-62.
    • (2009) J. Chromatogr. A , vol.1216 , pp. 2045-2062
    • Yang, M.1    Sun, J.2    Lu, Z.3    Chen, G.4    Guan, S.5    Liu, X.6
  • 8
    • 58749100897 scopus 로고    scopus 로고
    • Simultaneous quantification of both triterpenoid and steroidal saponins in various yunnan baiyao preparations using HPLC-UV and HPLC-MS
    • Liu XX, Wang L, Chen XQ, Deng XT, Cao Y, Wang Q. Simultaneous quantification of both triterpenoid and steroidal saponins in various Yunnan Baiyao preparations using HPLC-UV and HPLC-MS. J Sep Sci 2008; 31: 3834-46.
    • (2008) J. Sep. Sci. , vol.31 , pp. 3834-3846
    • Liu, X.X.1    Wang, L.2    Chen, X.Q.3    Deng, X.T.4    Cao, Y.5    Wang, Q.6
  • 9
    • 60349126812 scopus 로고    scopus 로고
    • Chemical analysis of the Chinese herbal medicine gan-cao licorice
    • Z hang Q, Ye M. Chemical analysis of the Chinese herbal medicine Gan-Cao (licorice). J Chromatogr A 2009; 1216: 1954-69.
    • (2009) J. Chromatogr. A , vol.1216 , pp. 1954-1969
    • Zhang, Q.1    Ye, M.2
  • 10
    • 33845768814 scopus 로고    scopus 로고
    • New developments in the chemistry and biology of the bioactive constituents of tanshen
    • Wang X, Morris-Natschke SL, Lee KH. New developments in the chemistry and biology of the bioactive constituents of Tanshen. Med Res Rev 2007; 27: 133-48.
    • (2007) Med. Res. Rev. , vol.27 , pp. 133-148
    • Wang, X.1    Morris-Natschke, S.L.2    Lee, K.H.3
  • 12
    • 66249147196 scopus 로고    scopus 로고
    • Crystal structure of the sodium-potassium pump at 2 4 Å resolution
    • Shinoda T, Ogawa H, Cornelius F, Toyoshima C. Crystal structure of the sodium-potassium pump at 2.4 Å resolution. Nature 2009; 459: 446-50.
    • (2009) Nature , vol.459 , pp. 446-450
    • Shinoda, T.1    Ogawa, H.2    Cornelius, F.3    Toyoshima, C.4
  • 15
    • 0028334076 scopus 로고
    • Ouabain binding kinetics of the rat alpha two and alpha three isoforms of the sodium-potassium adenosine triphosphate
    • O'Brien WJ, Lingrel JB, Wallick ET. Ouabain binding kinetics of the rat alpha two and alpha three isoforms of the sodium-potassium adenosine triphosphate. Arch Biochem Biophys 1994; 310: 32-9.
    • (1994) Arch. Biochem. Biophys. , vol.310 , pp. 32-39
    • O'Brien, W.J.1    Lingrel, J.B.2    Wallick, E.T.3
  • 18
    • 0027936031 scopus 로고
    • Understanding the sodium pump and its relevance to disease
    • Rose AM, Valdes R Jr. Understanding the sodium pump and its relevance to disease. Clin Chem 1994; 40: 1674-85.
    • (1994) Clin. Chem. , vol.40 , pp. 1674-1685
    • Rose, A.M.1    Valdes Jr., R.2
  • 19
    • 0018609054 scopus 로고
    • The role of the nervous system in the cardiovascular effects of digitalis
    • Gillis RA, Quest JA. The role of the nervous system in the cardiovascular effects of digitalis. Pharmacol Rev 1979; 31: 19-97.
    • (1979) Pharmacol. Rev. , vol.31 , pp. 19-97
    • Gillis, R.A.1    Quest, J.A.2
  • 20
    • 0031758268 scopus 로고    scopus 로고
    • Isozymes of the Na-K-ATPase: Heterogeneity in structure, diversity in function
    • Blanco G, Mercer RW. Isozymes of the Na-K-ATPase: heterogeneity in structure, diversity in function. Am J Physiol 1998; 275: F633-50.
    • (1998) Am. J. Physiol. , vol.275
    • Blanco, G.1    Mercer, R.W.2
  • 21
    • 0026636168 scopus 로고
    • NaK-ATPase: Isoform structure function and expression
    • Lingrel JB. Na,K-ATPase: isoform structure, function, and expression. J Bioenerg Biomembr 1992; 24: 263-70.
    • (1992) J. Bioenerg. Biomembr , vol.24 , pp. 263-270
    • Lingrel, J.B.1
  • 22
    • 77951883450 scopus 로고    scopus 로고
    • The physiological significance of the cardiotonic steroid/ ouabain-binding site of the Na K-ATPase
    • Lingrel JB. The physiological significance of the cardiotonic steroid/ ouabain-binding site of the Na,K-ATPase. Annu Rev Physiol 2010; 72: 395-412.
    • (2010) Annu. Rev. Physiol. , vol.72 , pp. 395-412
    • Lingrel, J.B.1
  • 23
    • 0027174426 scopus 로고
    • 2+ stores and cell responsiveness
    • 2+ stores and cell responsiveness. Am J Physiol 1993; 264: C1367-87.
    • (1993) Am. J. Physiol. , vol.264
    • Blaustein, M.P.1
  • 24
    • 21344450768 scopus 로고    scopus 로고
    • The Na/K-ATPase-mediated signal transduction as a target for new drug development
    • Xie Z, Xie J. The Na/K-ATPase-mediated signal transduction as a target for new drug development. Front Biosci 2005; 10: 3100-9.
    • (2005) Front. Biosci. , vol.10 , pp. 3100-3109
    • Xie, Z.1    Xie, J.2
  • 25
    • 2342487353 scopus 로고    scopus 로고
    • +-ATPase-mediated signal transduction: From protein interaction to cellular function
    • +-ATPase-mediated signal transduction: from protein interaction to cellular function. Mol Interv 2003; 3: 157-68.
    • (2003) Mol. Interv. , vol.3 , pp. 157-168
    • Xie, Z.1    Cai, T.2
  • 28
    • 0001874893 scopus 로고    scopus 로고
    • A short review on cardiotonic steroids and their aminoguanidine analogues
    • Melero CP, Medarde M, San Feliciano A. A short review on cardiotonic steroids and their aminoguanidine analogues. Molecules 2000; 5: 51-81.
    • (2000) Molecules. , vol.5 , pp. 51-81
    • Melero, C.P.1    Medarde, M.2    San Feliciano, A.3
  • 29
    • 0031925714 scopus 로고    scopus 로고
    • Digoxin revisited
    • Li-Saw-Hee FL, Lip GY. Digoxin revisited. QJM 1998; 91: 259-64.
    • (1998) QJM , vol.91 , pp. 259-264
    • Li-Saw-Hee, F.L.1    Lip, G.Y.2
  • 30
    • 0020002496 scopus 로고
    • 2+-ATPase in enriched nerve-ending plasma membranes
    • 2+-ATPase in enriched nerve-ending plasma membranes. Brain Res 1982; 235: 387-92.
    • (1982) Brain Res. , vol.235 , pp. 387-392
    • Lin, S.C.1    Way, E.L.2
  • 31
    • 0016145890 scopus 로고
    • The interrelationship between sodium and calcium fluxes across cell membranes
    • Blaustein MP. The interrelationship between sodium and calcium fluxes across cell membranes. Rev Physiol Biochem Pharmacol 1974; 70: 33-82.
    • (1974) Rev. Physiol. Biochem. Pharmacol. , vol.70 , pp. 33-82
    • Blaustein, M.P.1
  • 33
    • 38149063511 scopus 로고    scopus 로고
    • Preparative isolation of bufalin and cinobufagin from Chinese traditional medicine ChanSu
    • Yang Z, Luo H, Wang H, Hou H. Preparative isolation of bufalin and cinobufagin from Chinese traditional medicine ChanSu. J Chromatogr Sci 2008; 46: 81-5.
    • (2008) J. Chromatogr. Sci. , vol.46 , pp. 81-85
    • Yang, Z.1    Luo, H.2    Wang, H.3    Hou, H.4
  • 34
    • 0037184709 scopus 로고    scopus 로고
    • Effects of chansu a traditional Chinese medicine on the calcium transients of isolated cardiomyocytes: Cardiotoxicity due to more than Na K-ATPase blocking
    • Bick RJ, Poindexter BJ, Sweney RR, Dasgupta A. Effects of ChanSu, a traditional Chinese medicine, on the calcium transients of isolated cardiomyocytes: cardiotoxicity due to more than Na, K-ATPase blocking. Life Sci 2002; 72: 699-709.
    • (2002) Life Sci. , vol.72 , pp. 699-709
    • Bick, R.J.1    Poindexter, B.J.2    Sweney, R.R.3    Dasgupta, A.4
  • 35
    • 33645809108 scopus 로고    scopus 로고
    • 20S - Ginsenoside Rh2 a newly identified active ingredient of ginseng inhibits NMDA receptors in cultured rat hippocampal neurons
    • Lee E, Kim S, Chung KC, Choo MK, Kim DH, Nam G, et al. 20(S)- ginsenoside Rh2, a newly identified active ingredient of ginseng, inhibits NMDA receptors in cultured rat hippocampal neurons. Eur J Pharmacol 2006; 536: 69-77.
    • (2006) Eur. J. Pharmacol. , Issue.536 , pp. 69-77
    • Lee, E.1    Kim, S.2    Chung, K.C.3    Choo, M.K.4    Kim, D.H.5    Nam, G.6
  • 36
    • 6344294207 scopus 로고    scopus 로고
    • Rh2 a compound extracted from ginseng hypersensitizes multidrug-resistant tumor cells to chemotherapy
    • Jia WW, Bu X, Philips D, Yan H, Liu G, Chen X, et al. Rh2, a compound extracted from ginseng, hypersensitizes multidrug-resistant tumor cells to chemotherapy. Can J Physiol Pharmacol 2004; 82: 431-7.
    • (2004) Can. J. Physiol. Pharmacol. , vol.82 , pp. 431-437
    • Jia, W.W.1    Bu, X.2    Philips, D.3    Yan, H.4    Liu, G.5    Chen, X.6
  • 37
    • 1542755969 scopus 로고    scopus 로고
    • Saponins with low sugar chain from the leaves of panax notoginseng burk F H
    • Chen Y, Zhan E, Chen H, Duan X, Guo L. Saponins with low sugar chain from the leaves of Panax notoginseng (Burk) F H Chen. Zhong Yao Cai 2002; 25: 176-8.
    • (2002) Chen. Zhong. Yao. Cai. , vol.25 , pp. 176-178
    • Chen, Y.1    Zhan, E.2    Chen, H.3    Duan, X.4    Guo, L.5
  • 38
    • 58449127551 scopus 로고    scopus 로고
    • Triterpenoic acids of prunella vulgaris var lilacina and their cytotoxic activities in vitro
    • Lee IK, Kim DH, Lee SY, Kim KR, Choi SU, Hong JK, et al. Triterpenoic acids of Prunella vulgaris var lilacina and their cytotoxic activities in vitro. Arch Pharm Res 2008; 31: 1578-83.
    • (2008) Arch. Pharm. Res. , vol.31 , pp. 1578-1583
    • Lee, I.K.1    Kim, D.H.2    Lee, S.Y.3    Kim, K.R.4    Choi, S.U.5    Hong, J.K.6
  • 39
    • 0034119806 scopus 로고    scopus 로고
    • Anti-allergic and anti-inflammatory triterpenes from the herb of prunella vulgaris
    • Ryu SY, Oak MH, Yoon SK, Cho DI, Yoo GS, Kim TS, et al. Anti-allergic and anti-inflammatory triterpenes from the herb of Prunella vulgaris. Planta Med 2000; 66: 358-60.
    • (2000) Planta. Med. , vol.66 , pp. 358-360
    • Ryu, S.Y.1    Oak, M.H.2    Yoon, S.K.3    Cho, D.I.4    Yoo, G.S.5    Kim, T.S.6
  • 40
    • 48749132552 scopus 로고    scopus 로고
    • Localization and dynamic change of saikosaponin in root of bupleurum chinense
    • Tan LL, Cai X, Hu ZH, Ni XL. Localization and dynamic change of saikosaponin in root of Bupleurum chinense. J Integr Plant Biol 2008; 50: 951-7.
    • (2008) J. Integr. Plant. Biol. , vol.50 , pp. 951-957
    • Tan, L.L.1    Cai, X.2    Hu, Z.H.3    Ni, X.L.4
  • 42
    • 0024795225 scopus 로고
    • Determination of bile acids in bear gall drainage by thin layer chromatographic scanning
    • Wang FS, Xu LX, Zhao YJ, Liu AR, Jin LZ, Zhang XQ. Determination of bile acids in bear gall drainage by thin layer chromatographic scanning. Yao Xue Xue Bao 1989; 24: 397-400.
    • (1989) Yao. Xue. Xue. Bao. , vol.24 , pp. 397-400
    • Wang, F.S.1    Xu, L.X.2    Zhao, Y.J.3    Liu, A.R.4    Jin, L.Z.5    Zhang, X.Q.6
  • 44
    • 0033183768 scopus 로고    scopus 로고
    • Determination of sarsasapogenin in anemarrhena asphodeloides bunge by GC
    • 75
    • Liu Y, Chen W, Qiao C, Zhao N. Determination of sarsasapogenin in Anemarrhena asphodeloides Bunge by GC. Zhongguo Zhong Yao Za Zhi 1999; 24: 554-5, 75.
    • (1999) Zhongguo Zhong Yao. Za Zhi. , vol.24 , pp. 554-555
    • Liu, Y.1    Chen, W.2    Qiao, C.3    Zhao, N.4
  • 46
    • 58149494393 scopus 로고    scopus 로고
    • Simultaneous determination of jujuboside A B and betulinic acid in semen ziziphi spinosae by high performance liquid chromatography-evaporative light scattering detection
    • Z hang M, Zhang Y, Xie J. Simultaneous determination of jujuboside A, B and betulinic acid in semen Ziziphi spinosae by high performance liquid chromatography-evaporative light scattering detection. J Pharm Biomed Anal 2008; 48: 1467-70.
    • (2008) J. Pharm. Biomed. Anal. , vol.48 , pp. 1467-1470
    • Zhang, M.1    Zhang, Y.2    Xie, J.3
  • 47
    • 43949095483 scopus 로고    scopus 로고
    • The determination of glycyrrhizic acid in glycyrrhiza uralensis fisch ex DC zhi gan cao root and the dried aqueous extract by LC-DAD
    • Hennell JR, Lee S, Khoo CS, Gray MJ, Bensoussan A. The determination of glycyrrhizic acid in Glycyrrhiza uralensis Fisch ex DC (Zhi Gan Cao) root and the dried aqueous extract by LC-DAD. J Pharm Biomed Anal 2008; 47: 494-500.
    • (2008) J. Pharm. Biomed. Anal. , vol.47 , pp. 494-500
    • Hennell, J.R.1    Lee, S.2    Khoo, C.S.3    Gray, M.J.4    Bensoussan, A.5
  • 48
    • 38048999699 scopus 로고    scopus 로고
    • Effects of density on seedling growth and glycyrrhizinic acid content in glycyrrhiza uralensis
    • 81. Chinese.
    • Sun ZR, Zhai MP, Wang WQ, Li YR. Effects of density on seedling growth and glycyrrhizinic acid content in Glycyrrhiza uralensis. Zhongguo Zhong Yao Za Zhi 2007; 32: 2222-6, 81. Chinese.
    • (2007) Zhongguo Zhong Yao. Za Zhi. , vol.32 , pp. 2222-2226
    • Sun, Z.R.1    Zhai, M.P.2    Wang, W.Q.3    Li, Y.R.4
  • 49
    • 34548787353 scopus 로고    scopus 로고
    • Determination of astragalosides in the roots of Astragalus spp. using liquid chromatography tandem atmospheric pressure chemical ionization mass spectrometry
    • DOI 10.1002/pca.997
    • Xu Q, Ma X, Liang X. Determination of astragalosides in the roots of Astragalus spp using liquid chromatography tandem atmospheric pressure chemical ionization mass spectrometry. Phytochem Analysis 2007; 18: 419-27. (Pubitemid 47422798)
    • (2007) Phytochemical Analysis , vol.18 , Issue.5 , pp. 419-427
    • Xu, Q.1    Ma, X.2    Liang, X.3
  • 50
    • 0031945992 scopus 로고    scopus 로고
    • Two novel compounds from paeonia suffructicosa
    • Lin HC, Ding HY, Wu YC. Two novel compounds from Paeonia suffructicosa. J Nat Prod 1998; 61: 343-6.
    • (1998) J. Nat. Prod. , vol.61 , pp. 343-346
    • Lin, H.C.1    Ding, H.Y.2    Wu, Y.C.3
  • 51
    • 13244267082 scopus 로고    scopus 로고
    • Isolation and structure identification of C-25 epimers of inokosterone from achyranthes bidentata blume
    • Chinese
    • Zhu TT, Liang H, Zhao YY, Wang B. Isolation and structure identification of C-25 epimers of inokosterone from Achyranthes bidentata Blume. Yao Xue Xue Bao 2004; 39: 913-6. Chinese.
    • (2004) Yao. Xue. Xue. Bao. , vol.39 , pp. 913-916
    • Zhu, T.T.1    Liang, H.2    Zhao, Y.Y.3    Wang, B.4
  • 53
    • 67649933194 scopus 로고    scopus 로고
    • Purification of alkaloids from corydalis yanhusuo W T wang using preparative 2-D HPLC
    • Z hang J, Jin Y, Liu Y, Xiao Y, Feng J, Xue X, et al. Purification of alkaloids from Corydalis yanhusuo W T Wang using preparative 2-D HPLC. J Sep Sci 2009; 32: 1401-6.
    • (2009) J. Sep. Sci. , vol.32 , pp. 1401-1406
    • Zhang, J.1    Jin, Y.2    Liu, Y.3    Xiao, Y.4    Feng, J.5    Xue, X.6
  • 54
    • 1442349841 scopus 로고    scopus 로고
    • In vitro vasodilator mechanisms of the indole alkaloids rhynchophylline and isorhynchophylline isolated from the hook of uncaria rhynchophylla miquel
    • Z hang WB, Chen CX, Sim SM, Kwan CY. In vitro vasodilator mechanisms of the indole alkaloids rhynchophylline and isorhynchophylline, isolated from the hook of Uncaria rhynchophylla (Miquel). Naunyn Schmiedebergs Arch Pharmacol 2004; 369: 232-8.
    • (2004) Naunyn Schmiedebergs Arch. Pharmacol. , vol.369 , pp. 232-238
    • Zhang, W.B.1    Chen, C.X.2    Sim, S.M.3    Kwan, C.Y.4
  • 55
    • 0037310776 scopus 로고    scopus 로고
    • Pharmacological actions of uncaria alkaloids rhynchophylline and isorhynchophylline
    • Shi JS, Yu JX, Chen XP, Xu RX. Pharmacological actions of Uncaria alkaloids, rhynchophylline and isorhynchophylline. Acta Pharmacol Sin 2003; 24: 97-101.
    • (2003) Acta. Pharmacol. Sin. , vol.24 , pp. 97-101
    • Shi, J.S.1    Yu, J.X.2    Chen, X.P.3    Xu, R.X.4
  • 56
    • 33746757103 scopus 로고    scopus 로고
    • Metabolites of hirsuteine and hirsutine the major indole alkaloids of uncaria rhynchophylla in rats
    • Nakazawa T, Banba K, Hata K, Nihei Y, Hoshikawa A, Ohsawa K. Metabolites of hirsuteine and hirsutine, the major indole alkaloids of Uncaria rhynchophylla, in rats. Biol Pharm Bull 2006; 29: 1671-7.
    • (2006) Biol. Pharm. Bull. , vol.29 , pp. 1671-1677
    • Nakazawa, T.1    Banba, K.2    Hata, K.3    Nihei, Y.4    Hoshikawa, A.5    Ohsawa, K.6
  • 57
    • 0026515390 scopus 로고
    • Effects of hirsutine an antihypertensive indole alkaloid from uncaria rhynchophylla on intracellular calcium in rat thoracic aorta
    • Horie S, Yano S, Aimi N, Sakai S, Watanabe K. Effects of hirsutine, an antihypertensive indole alkaloid from Uncaria rhynchophylla, on intracellular calcium in rat thoracic aorta. Life Sci 1992; 50: 491-8.
    • (1992) Life Sci. , vol.50 , pp. 491-498
    • Horie, S.1    Yano, S.2    Aimi, N.3    Sakai, S.4    Watanabe, K.5
  • 58
    • 0025230434 scopus 로고
    • Vasodilative effects of indole alkaloids obtained from domestic plants uncaria rhynchophylla miq and amsonia elliptica roem et schult
    • Japanese.
    • Ozaki Y. Vasodilative effects of indole alkaloids obtained from domestic plants, Uncaria rhynchophylla Miq and Amsonia elliptica Roem et Schult. Nippon Yakurigaku Zasshi 1990; 95: 47-54. Japanese.
    • (1990) Nippon Yakurigaku Zasshi , vol.95 , pp. 47-54
    • Ozaki, Y.1
  • 59
    • 0036747181 scopus 로고    scopus 로고
    • Cucurbitacins from trichosanthes kirilowii as the inhibitory components on tyrosinase activity and melanin synthesis of B16/F10 melanoma cells
    • Oh H, Mun YJ, Im SJ, Lee SY, Song HJ, Lee HS, et al. Cucurbitacins from Trichosanthes kirilowii as the inhibitory components on tyrosinase activity and melanin synthesis of B16/F10 melanoma cells. Planta Med 2002; 68: 832-3.
    • (2002) Planta. Med. , vol.68 , pp. 832-833
    • Oh, H.1    Mun, Y.J.2    Im, S.J.3    Lee, S.Y.4    Song, H.J.5    Lee, H.S.6
  • 60
    • 61649114173 scopus 로고    scopus 로고
    • Cucurbitacin D isolated from trichosanthes kirilowii induces apoptosis in human hepatocellular carcinoma cells in vitro
    • Takahashi N, Yoshida Y, Sugiura T, Matsuno K, Fujino A, Yamashita U. Cucurbitacin D isolated from Trichosanthes kirilowii induces apoptosis in human hepatocellular carcinoma cells in vitro. Int Immunopharmacol 2009; 9: 508-13.
    • (2009) Int. Immunopharmacol. , vol.9 , pp. 508-513
    • Takahashi, N.1    Yoshida, Y.2    Sugiura, T.3    Matsuno, K.4    Fujino, A.5    Yamashita, U.6
  • 61
    • 0042657826 scopus 로고    scopus 로고
    • Immunomodulatory triterpenoids from the oleogum resin of boswellia carterii birdwood
    • Badria FA, Mikhaeil BR, Maatooq GT, Amer MM. Immunomodulatory triterpenoids from the oleogum resin of Boswellia carterii Birdwood. Z Naturforsch C 2003; 58: 505-16.
    • (2003) Z Naturforsch. C , vol.58 , pp. 505-516
    • Badria, F.A.1    Mikhaeil, B.R.2    Maatooq, G.T.3    Amer, M.M.4
  • 63
    • 0029348284 scopus 로고
    • Chemical constituents of the sparganium stoloniferum buch-ham
    • Chinese
    • Z hang S. Chemical constituents of the Sparganium stoloniferum Buch.-Ham. Zhongguo Zhong Yao Za Zhi 1995; 20: 486-7. Chinese.
    • (1995) Zhongguo Zhong Yao. Za Zhi. , vol.20 , pp. 486-487
    • Zhang, S.1
  • 64
    • 40949119894 scopus 로고    scopus 로고
    • Two new lanostane triterpenoids from poria cocos
    • Z heng Y, Yang XW. Two new lanostane triterpenoids from Poria cocos. J Asian Nat Prod Res 2008; 10: 323-8.
    • (2008) J. Asian Nat. Prod. Res. , vol.10 , pp. 323-328
    • Zheng, Y.1    Yang, X.W.2
  • 66
    • 8644286660 scopus 로고    scopus 로고
    • Pharmacokinetics of magnesium lithospermate B after intravenous administration in beagle dogs
    • Li XC, Yu C, Sun WK, Liu GY, Jia JY, Wang YP. Pharmacokinetics of magnesium lithospermate B after intravenous administration in beagle dogs. Acta Pharmacol Sin 2004; 25: 1402-7.
    • (2004) Acta. Pharmacol. Sin. , vol.25 , pp. 1402-1407
    • Li, X.C.1    Yu, C.2    Sun, W.K.3    Liu, G.Y.4    Jia, J.Y.5    Wang, Y.P.6
  • 67
    • 0028217687 scopus 로고
    • Inhibition of collagen hydroxylation by lithospermic acid magnesium salt a novel compound isolated from salviae miltiorrhizae radix
    • Shigematsu T, Tajima S, Nishikawa T, Murad S, Pinnell SR, Nishioka I. Inhibition of collagen hydroxylation by lithospermic acid magnesium salt, a novel compound isolated from Salviae miltiorrhizae Radix. Biochim Biophys Acta 1994; 1200: 79-83.
    • (1994) Biochim. Biophys. Acta. , vol.1200 , pp. 79-83
    • Shigematsu, T.1    Tajima, S.2    Nishikawa, T.3    Murad, S.4    Pinnell, S.R.5    Nishioka, I.6
  • 68
    • 0037203864 scopus 로고    scopus 로고
    • Polyphenolics of salvia - A review
    • Lu Y, Foo LY. Polyphenolics of Salvia - a review. Phytochemistry 2002; 59: 117-40.
    • (2002) Phytochemistry , vol.59 , pp. 117-140
    • Lu, Y.1    Foo, L.Y.2
  • 69
    • 0033799632 scopus 로고    scopus 로고
    • Free radical scavenging and inhibition of lipid peroxidation by magnesium lithospermate B
    • Wu XJ, Wang YP, Wang W, Sun WK, Xu YM, Xuan LJ. Free radical scavenging and inhibition of lipid peroxidation by magnesium lithospermate B. Acta Pharmacol Sin 2000; 21: 855-8.
    • (2000) Acta. Pharmacol. Sin. , vol.21 , pp. 855-858
    • Wu, X.J.1    Wang, Y.P.2    Wang, W.3    Sun, W.K.4    Xu, Y.M.5    Xuan, L.J.6
  • 70
    • 0031969630 scopus 로고    scopus 로고
    • Comparative study of seventeen salvia plants: Aldose reductase inhibitory activity of water and MeOH extracts and liquid chromatographymass spectrometry LC-MS analysis of water extracts
    • Kasimu R, Tanaka K, Tezuka Y, Gong ZN, Li JX, Basnet P, et al. Comparative study of seventeen Salvia plants: aldose reductase inhibitory activity of water and MeOH extracts and liquid chromatographymass spectrometry (LC-MS) analysis of water extracts. Chem Pharm Bull 1998; 46: 500-4.
    • (1998) Chem. Pharm. Bull. , vol.46 , pp. 500-504
    • Kasimu, R.1    Tanaka, K.2    Tezuka, Y.3    Gong, Z.N.4    Li, J.X.5    Basnet, P.6
  • 71
    • 0028837630 scopus 로고
    • Confirmation that magnesium lithospermate B has a hydroxyl radical-scavenging action
    • Yokozawa T, Chung HY, Dong E, Oura H. Confirmation that magnesium lithospermate B has a hydroxyl radical-scavenging action. Exp Toxicol Pathol 1995; 47: 341-4.
    • (1995) Exp. Toxicol. Pathol. , vol.47 , pp. 341-344
    • Yokozawa, T.1    Chung, H.Y.2    Dong, E.3    Oura, H.4
  • 72
    • 0026508229 scopus 로고
    • Effect of magnesium lithospermate B in rats with sodium-induced hypertension and renal failure
    • Yokozawa T, Lee TW, Oura H, Nonaka G, Nishioka I. Effect of magnesium lithospermate B in rats with sodium-induced hypertension and renal failure. Nephron 1992; 60: 460-5.
    • (1992) Nephron. , vol.60 , pp. 460-465
    • Yokozawa, T.1    Lee, T.W.2    Oura, H.3    Nonaka, G.4    Nishioka, I.5
  • 76
    • 34249991729 scopus 로고    scopus 로고
    • Ouabain activates signaling pathways associated with cell death in human neuroblastoma
    • Kulikov A, Eva A, Kirch U, Boldyrev A, Scheiner-Bobis G. Ouabain activates signaling pathways associated with cell death in human neuroblastoma. Biochim Biophys Acta 2007; 1768: 1691-702.
    • (2007) Biochim. Biophys. Acta. , vol.1768 , pp. 1691-1702
    • Kulikov, A.1    Eva, A.2    Kirch, U.3    Boldyrev, A.4    Scheiner-Bobis, G.5
  • 77
    • 14944354081 scopus 로고    scopus 로고
    • Simultaneous determination of triterpene saponins in ginseng drugs by highperformance liquid chromatography
    • Z hu S, Zou K, Cai S, Meselhy MR, Komatsu K. Simultaneous determination of triterpene saponins in ginseng drugs by highperformance liquid chromatography. Chem Pharm Bull 2004; 52: 995-8.
    • (2004) Chem. Pharm. Bull. , vol.52 , pp. 995-998
    • Zhu, S.1    Zou, K.2    Cai, S.3    Meselhy, M.R.4    Komatsu, K.5
  • 78
  • 79
    • 3142621044 scopus 로고    scopus 로고
    • Proof of the mysterious efficacy of ginseng: Basic and clinical trials: Metabolic activation of ginsenoside: Deglycosylation by intestinal bacteria and esterification with fatty acid
    • Hasegawa H. Proof of the mysterious efficacy of ginseng: basic and clinical trials: metabolic activation of ginsenoside: deglycosylation by intestinal bacteria and esterification with fatty acid. J Pharmacol Sci 2004; 95: 153-7.
    • (2004) J. Pharmacol. Sci. , vol.95 , pp. 153-157
    • Hasegawa, H.1
  • 81
    • 0022996988 scopus 로고
    • Cardiovascular pharmacology of panax notoginseng Burk F H chen and salvia miltiorrhiza
    • Lei XL, Chiou GC. Cardiovascular pharmacology of Panax notoginseng (Burk) F H Chen and Salvia miltiorrhiza. Am J Chin Med 1986; 14: 145-52.
    • (1986) Am. J. Chin. Med. , vol.14 , pp. 145-152
    • Lei, X.L.1    Chiou, G.C.2
  • 82
    • 0037328536 scopus 로고    scopus 로고
    • Panax notoginseng burk effects on fibrinogen and lipid plasma level in rats fed on a high-fat diet
    • Cicero AF, Vitale G, Savino G, Arletti R. Panax notoginseng (Burk) effects on fibrinogen and lipid plasma level in rats fed on a high-fat diet. Phytother Res 2003; 17: 174-8.
    • (2003) Phytother. Res. , vol.17 , pp. 174-178
    • Cicero, A.F.1    Vitale, G.2    Savino, G.3    Arletti, R.4
  • 84
    • 36849043044 scopus 로고    scopus 로고
    • Ginsenosides: Are any of them candidates for drugs acting on the central nervous system
    • Nah SY, Kim DH, Rhim H. Ginsenosides: are any of them candidates for drugs acting on the central nervous system? Cns Drug Rev 2007; 13: 381-404.
    • (2007) Cns. Drug. Rev. , vol.13 , pp. 381-404
    • Nah, S.Y.1    Kim, D.H.2    Rhim, H.3
  • 86
    • 79551666444 scopus 로고    scopus 로고
    • The optimization of different combinations and distributions between danshen and sanqi along with syn thetical information evaluation
    • Chinese
    • Shang HC, Gao XM, Guo LP. The optimization of different combinations and distributions between Danshen and Sanqi along with syn thetical information evaluation. Drug Evaluation 2005; 2: 209-11. Chinese.
    • (2005) Drug Evaluation , vol.2 , pp. 209-211
    • Shang, H.C.1    Gao, X.M.2    Guo, L.P.3
  • 87
    • 18144404348 scopus 로고    scopus 로고
    • Simultaneous determination of six phenolic constituents of danshen in human serum using liquid chromatography/tandem mass spectrometry
    • Li XC, Yu C, Cai YB, Liu GY, Jia JY, Wang YP. Simultaneous determination of six phenolic constituents of danshen in human serum using liquid chromatography/tandem mass spectrometry. J Chromatogr B 2005; 820: 41-7.
    • (2005) J. Chromatogr. B , vol.820 , pp. 41-47
    • Li, X.C.1    Yu, C.2    Cai, Y.B.3    Liu, G.Y.4    Jia, J.Y.5    Wang, Y.P.6
  • 89
    • 28044453933 scopus 로고    scopus 로고
    • Liquid chromatography mass spectrometric analysis of rat samples for in vivo metabolism and pharmacokinetic studies of ginsenoside Rh2
    • Oian TX, Cai ZW, Wong RNS, Jiang ZH. Liquid chromatography mass spectrometric analysis of rat samples for in vivo metabolism and pharmacokinetic studies of ginsenoside Rh2. Rapid Commun Mass Sp 2005; 19: 3549-54.
    • (2005) Rapid. Commun. Mass. Sp. , vol.19 , pp. 3549-3554
    • Oian, T.X.1    Cai, Z.W.2    Wong, R.N.S.3    Jiang, Z.H.4
  • 90
    • 0025856240 scopus 로고
    • Significance of cation transport in control of energy metabolism and thermogenesis
    • Clausen T, Van Hardeveld C, Everts ME. Significance of cation transport in control of energy metabolism and thermogenesis. Physiol Rev 1991; 71: 733-74.
    • (1991) Physiol. Rev. , vol.71 , pp. 733-774
    • Clausen, T.1    Van Hardeveld, C.2    Everts, M.E.3
  • 91
    • 0036479054 scopus 로고    scopus 로고
    • Mitochondrial permeability transition in acute neurodegeneration
    • Friberg H, Wieloch T. Mitochondrial permeability transition in acute neurodegeneration. Biochimie 2002; 84: 241-50.
    • (2002) Biochimie. , vol.84 , pp. 241-250
    • Friberg, H.1    Wieloch, T.2
  • 92
    • 0019989380 scopus 로고
    • Energy-requiring cell functions in the ischemic brain their critical supply and possible inhibition in protective therapy
    • Astrup J. Energy-requiring cell functions in the ischemic brain. Their critical supply and possible inhibition in protective therapy. J Neurosurg 1982; 56: 482-97.
    • (1982) J. Neurosurg. , vol.56 , pp. 482-497
    • Astrup, J.1
  • 94
    • 33745888419 scopus 로고    scopus 로고
    • Cardiac glycosides provide neuroprotection against ischemic stroke: Discovery by a brain slice-based compound screening platform
    • USA
    • Wang JK, Portbury S, Thomas MB, Barney S, Ricca DJ, Morris DL, et al. Cardiac glycosides provide neuroprotection against ischemic stroke: discovery by a brain slice-based compound screening platform. Proc Natl Acad Sci USA 2006; 103: 10461-6.
    • (2006) Proc. Natl. Acad. Sci. , vol.103 , pp. 10461-10466
    • Wang, J.K.1    Portbury, S.2    Thomas, M.B.3    Barney, S.4    Ricca, D.J.5    Morris, D.L.6
  • 95
    • 0029704284 scopus 로고    scopus 로고
    • Influences of ginsenosides Rb1 and Rg1 on reversible focal brain ischemia in rats
    • Z hang YG, Liu TP. Influences of ginsenosides Rb1 and Rg1 on reversible focal brain ischemia in rats. Zhongguo Yao Li Xue Bao 1996; 17: 44-8.
    • (1996) Zhongguo Yao. Li Xue. Bao. , vol.17 , pp. 44-48
    • Zhang, Y.G.1    Liu, T.P.2
  • 96
    • 11844298464 scopus 로고    scopus 로고
    • 3 on cerebral ischemia in rats
    • DOI 10.1016/j.neulet.2004.10.030, PII S0304394004012935
    • Tian J, Fu F, Geng M, Jiang Y, Yang J, Jiang W, et al. Neuroprotective effect of 20(S)-ginsenoside Rg3 on cerebral ischemia in rats. Neurosci Lett 2005; 374: 92-7. (Pubitemid 40092203)
    • (2005) Neuroscience Letters , vol.374 , Issue.2 , pp. 92-97
    • Tian, J.1    Fu, F.2    Geng, M.3    Jiang, Y.4    Yang, J.5    Jiang, W.6    Wang, C.7    Liu, K.8
  • 97
    • 33845360902 scopus 로고    scopus 로고
    • Protective effect of ginsenoside Re against cerebral ischemia/reperfusion damage in rats
    • Z hou XM, Cao YL, Dou DQ. Protective effect of ginsenoside Re against cerebral ischemia/reperfusion damage in rats. Biol Pharm Bull 2006; 29: 2502-5.
    • (2006) Biol. Pharm. Bull. , vol.29 , pp. 2502-2505
    • Zhou, X.M.1    Cao, Y.L.2    Dou, D.Q.3
  • 98
    • 34548130846 scopus 로고    scopus 로고
    • Neuroprotective effects of ginsenoside Rb1 on transient cerebral ischemia in rats
    • Yuan QL, Yang CX, Xu P, Gao XQ, Deng L, Chen P, et al. Neuroprotective effects of ginsenoside Rb1 on transient cerebral ischemia in rats. Brain Res 2007; 1167: 1-12.
    • (2007) Brain Res. , vol.1167 , pp. 1-12
    • Yuan, Q.L.1    Yang, C.X.2    Xu, P.3    Gao, X.Q.4    Deng, L.5    Chen, P.6
  • 99
    • 45849093732 scopus 로고    scopus 로고
    • Neuroprotection of ginsenoside Re in cerebral ischemia-reperfusion injury in rats
    • Chen LM, Zhou XM, Cao YL, Hu WX. Neuroprotection of ginsenoside Re in cerebral ischemia-reperfusion injury in rats. J Asian Nat Prod Res 2008; 10: 439-45.
    • (2008) J. Asian Nat. Prod. Res. , vol.10 , pp. 439-445
    • Chen, L.M.1    Zhou, X.M.2    Cao, Y.L.3    Hu, W.X.4
  • 100
    • 68149182637 scopus 로고    scopus 로고
    • Anti-ischemic activities of aralia cordata and its active component oleanolic acid
    • Cho SO, Ban JY, Kim JY, Ju HS, Lee IS, Song KS, et al. Anti-ischemic activities of Aralia cordata and its active component, oleanolic acid. Arch Pharm Res 2009; 32: 923-32.
    • (2009) Arch. Pharm. Res. , vol.32 , pp. 923-932
    • Cho, S.O.1    Ban, J.Y.2    Kim, J.Y.3    Ju, H.S.4    Lee, I.S.5    Song, K.S.6


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