Magnesium lithospermate B possesses inhibitory activity on Na +,K+-ATPase and neuroprotective effects against ischemic stroke

Acta Pharmacologica Sinica

Volumn 28, Issue 5, 2007, Pages 609-615

  Tzen, Jason T C ^a   Jinn, Tzyy Rong ^a   Chen, Yi Ching ^a   Li, Feng Yin ^a   Cheng, Fu Chou ^b   Shi, Li Shian ^c   She, Hank K H ^d   Chen, Balance C M ^a   Hsieh, Vic ^a   Tu, Mu Lin ^a  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^c NATIONAL FORMOSA UNIVERSITY   (Taiwan)

^d Herbal Source Biotechnology Co   (Taiwan)

Author keywords

Cardiac glycosides; Magnesium lithospermate B; Na+,K + ATPase; Neuroprotection; Ouabain; Salvia miltiorrhiza

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM) INHIBITOR; CARDIAC GLYCOSIDE; MAGNESIUM LITHOSPERMATE; OUABAIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOASSAY; BRAIN INFARCTION SIZE; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG POTENCY; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; HEART PROTECTION; MALE; NEUROPROTECTION; NITROBLUE TETRAZOLIUM TEST; NONHUMAN; RAT; SALVIA MILTIORRHIZA; STRUCTURAL HOMOLOGY;

ANIMALS; BRAIN ISCHEMIA; DRUGS, CHINESE HERBAL; ENZYME INHIBITORS; FREE RADICAL SCAVENGERS; GERBILLINAE; HUMANS; MALE; MOLECULAR STRUCTURE; NEUROPROTECTIVE AGENTS; OUABAIN; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SODIUM-POTASSIUM-EXCHANGING ATPASE;

EID: 34247874665     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2007.00544.x     Document Type: Article

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