Metabolites of hirsuteine and hirsutine, the major indole alkaloids of Uncaria rhynchophylla, in rats

Biological and Pharmaceutical Bulletin

Volumn 29, Issue 8, 2006, Pages 1671-1677

  Nakazawa, Takahiro ^a   Banba, Koh Ichi ^a   Hata, Kazumasa ^a   Nihei, Yutaka ^a   Hoshikawa, Ayumi ^a   Ohsawa, Keisuke ^a  

^a TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Hirsuteine; Hirsutine; Hydroxylation; Metabolite; Uncaria

Indexed keywords

11 HYDROXYHIRSUTEINE 11 O BETA GLUCURONIDE; 11 HYDROXYHIRSUTINE; CIMETIDINE; DRUG METABOLITE; GLUCURONIDE; HIRSUTEINE; HIRSUTINE; INDOLE ALKALOID; PLANT EXTRACT; PROADIFEN; UNCARIA RHYNCHOPHYLLA EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILE FLOW; CONTROLLED STUDY; DRUG EXCRETION; DRUG HYDROXYLATION; DRUG INHIBITION; DRUG METABOLISM; GLUCURONIDATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER MICROSOME; MALE; MEDICINAL PLANT; NONHUMAN; RAT; UNCARIA RHYNCHOPHYLLA; URINARY EXCRETION;

ALKALOIDS; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYDROXYLATION; MAGNETIC RESONANCE SPECTROSCOPY; MALE; RATS; RATS, SPRAGUE-DAWLEY; SPECTROPHOTOMETRY, INFRARED; UNCARIA;

EID: 33746757103     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.29.1671     Document Type: Article

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