Heterotrimeric Gαi proteins are regulated by lipopolysaccharide and are anti-inflammatory in endotoxemia and polymicrobial sepsis

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1813, Issue 3, 2011, Pages 466-472

  Fan, Hongkuan ^a   Li, Pengfei ^a,b   Zingarelli, Basilia ^c   Borg, Keith ^a   Halushka, Perry V ^a   Birnbaumer, Lutz ^d   Cook, James A ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b JILIN UNIVERSITY   (China)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Cecal ligation and puncture; G i protein; LPS; Mastoparan; Pertussis toxin

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MASTOPARAN; MYELOPEROXIDASE; PERTUSSIS TOXIN; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BACTERIAL LOAD; BLOOD; CELL POPULATION; CELL STIMULATION; CONTROLLED STUDY; ENDOTOXEMIA; ENZYME ACTIVATION; IMMUNOPRECIPITATION; IN VIVO STUDY; LUNG PARENCHYMA; MORTALITY; MOUSE; NONHUMAN; PERITONEAL FLUID; POLYMICROBIAL SEPSIS; PRIORITY JOURNAL; SEPSIS; SIGNAL TRANSDUCTION; SPLEEN; TISSUE;

ANIMALS; BACTERIAL LOAD; CECUM; CELL LINE; CYTOKINES; ENDOTOXEMIA; GENE DELETION; GTP-BINDING PROTEIN ALPHA SUBUNIT, GI2; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; LIPOPOLYSACCHARIDES; MICE; MICE, KNOCKOUT; PEPTIDES; PEROXIDASE; PERTUSSIS TOXIN; SEPSIS; SPLEEN; T-LYMPHOCYTES, HELPER-INDUCER; WASP VENOMS;

BACTERIA (MICROORGANISMS); MUS;

EID: 79551633369     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2011.01.012     Document Type: Article

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