P38-Targeted inhibition of interleukin-12 expression by ethanol extract from Cordyceps bassiana in lipopolysaccharide-activated macrophages

Immunopharmacology and Immunotoxicology

Volumn 33, Issue 1, 2011, Pages 90-96

  Byeon, Se Eun ^a   Lee, Jaehwi ^b   Yoo, Byong Chul ^c   Sung, Gi Ho ^d   Kim, Tae Woong ^a   Park, Hyoung Jin ^e   Cho, Jae Youl ^f  

^a Kangwon National University   (South Korea)

^b Chung Ang University   (South Korea)

^c National Cancer Center   (South Korea)

^d OREGON STATE UNIVERSITY   (United States)

^e Hallym University   (South Korea)

^f Sungkyunkwan University   (South Korea)

Author keywords

AP 1 translocation; Cordyceps bassiana; interleukin 12; macrophage; p38 activation

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALCOHOL; CORDYCEPS BASSIANA EXTRACT; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12; LIPOPOLYSACCHARIDE; PLANT EXTRACT; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ARTICLE; CELL VIABILITY; CORDYCEPS; CYTOKINE PRODUCTION; DENDRITIC CELL; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG TARGETING; GENETIC TRANSCRIPTION; IMMUNOBLOTTING; IMMUNOMODULATION; MACROPHAGE ACTIVATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TH1 CELL;

ANIMALS; CELL PROLIFERATION; CELL SURVIVAL; CORDYCEPS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ETHANOL; HEK293 CELLS; HUMANS; IMMUNOBLOTTING; IMMUNOLOGIC FACTORS; INTERFERON-GAMMA; INTERLEUKIN-12; LIPOPOLYSACCHARIDES; LUCIFERASES; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED BALB C; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPLEEN; TRANSCRIPTION FACTOR AP-1; TRANSFECTION;

BASIDIOMYCOTA; CORDYCEPS; CORDYCEPS BASSIANA;

EID: 79551610863     PISSN: 08923973     EISSN: 15322513     Source Type: Journal    
DOI: 10.3109/08923973.2010.482137     Document Type: Article

References (21)

1. Bachelez, H. Immunopathogenesis of psoriasis: recent insights on the role of adaptive and innate immunity. J. Autoimmun. 2005, 25 Suppl, 69-73.
2. Menter, A. Te status of biologic therapies in the treatment of moderate to severe psoriasis. Cutis. 2009, 84, 14-24.
3. Pourazar, J., Mudway, I.S., Samet, J.M., Helleday, R., Blomberg, A., Wilson, S.J., Frew, A.J., Kelly, F.J., Sandström, T. Diesel exhaust activates redox-sensitive transcription factors and kinases in human airways. Am. J. Physiol. Lung Cell Mol. Physiol. 2005, 289, L724-30.
4. Lee, C.H., Kim S.Y. NF-kB and Terapeutic Approach. Biomol Ter 2009, 17, 219-240.
5. Rahman, I., Marwick, J., Kirkham, P. Redox modulation of chro-matin remodeling: impact on histone acetylation and deacetyla-tion, NF-kappaB and pro-infammatory gene expression. Biochem. Pharmacol. 2004, 68, 1255-67.
6. García-Lafuente, A., Guillamón, E., Villares, A., Rostagno, M.A., Martínez, J.A. Flavonoids as anti-infammatory agents: implica-tions in cancer and cardiovascular disease. Infamm. Res. 2009, 58, 537-52.
7. Zhou, X., Gong, Z., Su, Y., Lin, J., Tang, K. Cordyceps fungi: natu-ral products, pharmacological functions and developmental products. J. Pharm. Pharmacol. 2009, 61, 279-91.
8. Ng, T.B., Wang, H.X. Pharmacological actions of Cordyceps, a prized folk medicine. J. Pharm. Pharmacol. 2005, 57, 1509-19.
9. Lee, Y.G., Byeon, S.E., Kim, J.Y., Lee, J.Y., Rhee, M.H., Hong, S., Wu, J.C., Lee, H.S., Kim, M.J., Cho, D.H., Cho, J.Y. Immunomodulatory efect of Hibiscus cannabinus extract on macrophage functions. J. Ethnopharmacol. 2007, 113, 62-71.
10. Cho, J.Y. Non-specifc anti-proliferative efect of FTY720, a deriva-tive of fungal metabolite from Iscaria sinclarii. Arch. Pharm. Res. 2008, 31, 160-6.
11. Yeon, J.A., Kim, S.J. Neuroprotective efect of taurine against oxi-dative stress-induced damages in neuronal cells. Biomol Ter 2010, 18, 24-31.
12. Kim, JY., Lee, Y.G., Kim, M.Y., Byeon, S.E., Rhee, M.H., Park, J., Katz, D.R., Chain, B.M., Cho, JY. Src-mediated regulation of infammatory responses by actin polymerization. Biochem. Pharmacol. 2010, 79, 431-43.
13. Jeon, S.J., Kwon, K.J., Shin, S., Lee, S.H., Rhee, SY., Han, S.H., Lee, J., Kim, H.Y., Cheong, J.H., Ryu, J.H., Min, B.S., Ko, K.H., Shin, CY. Inhibitory efects of Coptis japonica alkaloids on the LPS-induced activation of BV2 microglial cells. Biomol Ter 2009, 17, 70-78.
14. Noh, M., Lee, S.H. 15-Hydroxyprostaglandin dehydrogenase is associated with the troglitazone-induced promotion of adipocyte diferentiation in human bone marrow mesenchymal stem cells. Biomol Ter 2010, 18, 16-23.
15. Lee, H.J., Hyun, E.A., Yoon, W.J., Kim, B.H., Rhee, M.H., Kang, H.K., Cho, JY., Yoo, E.S. In vitro anti-infammatory and anti-oxidative efects of Cinnamomum camphora extracts. J. Ethnopharmacol. 2006, 103, 208-16.
16. Lee, Y.G., Lee, W.M., Kim, JY., Lee, JY., Lee, I.K., Yun, B.S., Rhee, M.H., Cho, JY. Src kinase-targeted anti-infammatory activ-ity of davallialactone from Inonotus xeranticus in lipopolysac-charide-activated RAW264.7 cells. Br. J. Pharmacol. 2008, 154, 852-63.
17. Youn, H.S., Lee, J.Y., Saitoh, S.I., Miyake, K., Kang, K.W., Choi, Y.J., Hwang, D.H. Suppression of MyD88-and TRIF-dependent sign-aling pathways of Toll-like receptor by (-)-epigallocatechin-3-gal-late, a polyphenol component of green tea. Biochem. Pharmacol. 2006, 72, 850-9.
18. Verstak, B., Nagpal, K., Bottomley, S.P., Golenbock, D.T., Hertzog, P.J., Mansell, A. MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2-and TLR4-mediated NF-kappaB proinfammatory responses. J. Biol. Chem. 2009, 284, 24192-203.
19. Dokter, W.H., Esselink, M.T., Halie, M.R., Vellenga, E. Interleukin-4 inhibits the lipopolysaccharide-induced expression of c-jun and c-fos messenger RNA and activator protein-1 binding activity in human monocytes. Blood 1993, 81, 337-43
20. Baldwin, A.S. Jr. Te NF-kappa B and I kappa B proteins: new discoveries and insights. Annu. Rev. Immunol. 1996, 14, 649-83.
21. Karin, M., Gallagher, E. TNFR signaling: ubiquitin-conjugated TRAFfc signals control stop-and-go for MAPK signaling com-plexes. Immunol. Rev. 2009, 228, 225-40.