Inhibitory effects of Coptis japonica alkaloids on the LPS-induced activation of BV2 microglial cells

Biomolecules and Therapeutics

Volumn 17, Issue 1, 2009, Pages 70-78

  Jeon, Se Jin ^a   Kwon, Kyung Ja ^b   Shin, Sunmi ^a   Lee, Sung Hoon ^a   Rhee, So Young ^a   Han, Seol Heui ^b   Lee, Jongmin ^b   Kim, Han Young ^b   Cheong, Jae Hoon ^c   Ryu, Jong Hoon ^d   Min, Byung Sun ^e   Ko, Kwang Ho ^a   Shin, Chan Young ^b  

^a Seoul National University   (South Korea)

^b Konkuk University School of Medicine   (South Korea)

^c Sahmyook University   (South Korea)

^d Kyung Hee University   (South Korea)

^e Catholic University of Daegu   (South Korea)

Author keywords

Coptis japonica; Inducible nitric oxide synthase (iNOS); Matrix metalloproteinase 9 (MMP 9); Microglia; Nitric oxide (NO)

Indexed keywords

BERBERINE DERIVATIVE; COPTISINE; EPI BERBERINE; GELATINASE B; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; LUCIFERASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NITRIC OXIDE; PALMATINE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; COPTIS; COPTIS JAPONICA; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE ACTIVITY; IMMUNOSTIMULATION; MEDIATOR RELEASE; MICROGLIA; NEUROMODULATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN INDUCTION; REPORTER GENE;

COPTIS JAPONICA;

EID: 69549097571     PISSN: 19769148     EISSN: None     Source Type: Journal    
DOI: 10.4062/biomolther.2009.17.1.70     Document Type: Article

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