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Volumn 62, Issue , 2011, Pages 217-232

Antiestrogens and their therapeutic applications in breast cancer and other diseases

Author keywords

breast cancer; cancer prevention; estrogen; selective estrogen receptor modulators (SERMs)

Indexed keywords

AFIMOXIFENE; ANTIESTROGEN; ARZOXIFENE; BAZEDOXIFENE; ESTROGEN; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FULVESTRANT; N BUTYL 11 (3,17BETA DIHYDROXYESTRA 1,3,5(10) TRIEN 7ALPHA YL) N METHYLUNDECANAMIDE; OSPEMIFENE; RALOXIFENE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; STEROID RECEPTOR COACTIVATOR 1; TAMOXIFEN CITRATE; TOREMIFENE;

EID: 79551584513     PISSN: 00664219     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev-med-052209-100305     Document Type: Article
Times cited : (77)

References (99)
  • 1
    • 33646568784 scopus 로고    scopus 로고
    • Patterns of cancer incidence, mortality, and prevalence across five continents: Defining priorities to reduce cancer disparities in different geographic regions of the world
    • Kamangar F, Dores GM, Anderson WF. 2006. Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world. J. Clin. Oncol. 24:2137-50
    • (2006) J. Clin. Oncol. , vol.24 , pp. 2137-50
    • Kamangar, F.1    Dores, G.M.2    Anderson, W.F.3
  • 3
    • 0036488531 scopus 로고    scopus 로고
    • Endocrine-responsive breast cancer and strategies for combatting resistance
    • Ali S, Coombes RC. 2002. Endocrine-responsive breast cancer and strategies for combatting resistance. Nat. Rev. Cancer 2:101-12
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 101-12
    • Ali, S.1    Coombes, R.C.2
  • 4
    • 0032499704 scopus 로고    scopus 로고
    • Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene
    • Fisher CR, Graves KH, Parlow AF, et al. 1998. Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene. Proc. Natl. Acad. Sci. USA 95:6965-70
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 6965-70
    • Fisher, C.R.1    Graves, K.H.2    Parlow, A.F.3
  • 5
    • 0027429548 scopus 로고
    • Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene
    • Lubahn DB, Moyer JS, Golding TS, et al. 1993. Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene. Proc. Natl. Acad. Sci. USA 90:11162-66
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11162-66
    • Lubahn, D.B.1    Moyer, J.S.2    Golding, T.S.3
  • 6
    • 13044292640 scopus 로고    scopus 로고
    • Generation and reproductive phenotypes of mice lacking estrogen receptor beta
    • Krege JH, Hodgin JB, Couse JF, et al. 1998. Generation and reproductive phenotypes of mice lacking estrogen receptor beta. Proc. Natl. Acad. Sci. USA 95:15677-82
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 15677-82
    • Krege, J.H.1    Hodgin, J.B.2    Couse, J.F.3
  • 8
    • 0036632231 scopus 로고    scopus 로고
    • Elucidation of estrogen receptor function in bone with the use of mouse models
    • Windahl SH, Andersson G, Gustafsson JA. 2002. Elucidation of estrogen receptor function in bone with the use of mouse models. Trends Endocrinol. Metab. 13:195-200
    • (2002) Trends Endocrinol. Metab. , vol.13 , pp. 195-200
    • Windahl, S.H.1    Andersson, G.2    Gustafsson, J.A.3
  • 9
    • 84967614664 scopus 로고    scopus 로고
    • Sex steroids and the construction and conservation of the adult skeleton
    • Riggs BL, Khosla S, Melton LJ 3rd. 2002. Sex steroids and the construction and conservation of the adult skeleton. Endocr. Rev. 23:279-302
    • (2002) Endocr. Rev. , vol.23 , pp. 279-302
    • Riggs, B.L.1    Khosla, S.2    Melton Iii, L.J.3
  • 10
    • 0037125379 scopus 로고    scopus 로고
    • Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial
    • Rossouw JE, AndersonGL,Prentice RL, et al. 2002. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. JAMA 288:321-33
    • (2002) JAMA , vol.288 , pp. 321-33
    • Rossouw, J.E.1    Anderson, G.L.2    Prentice, R.L.3
  • 11
    • 0017093859 scopus 로고
    • Menopause and risk of cardiovascular disease: The Framingham study
    • Kannel WB, Hjortland MC, McNamara PM, et al. 1976. Menopause and risk of cardiovascular disease: the Framingham study. Ann. Intern. Med. 85:447-52
    • (1976) Ann. Intern. Med. , vol.85 , pp. 447-52
    • Kannel, W.B.1    Hjortland, M.C.2    McNamara, P.M.3
  • 13
    • 0031866317 scopus 로고    scopus 로고
    • Hormone replacement therapy,heart disease, and other considerations
    • Barrett-ConnorE,GradyD.1998. Hormone replacement therapy,heart disease, and other considerations. Annu. Rev. Public Health 19:55-72
    • (1998) Annu. Rev. Public Health , vol.19 , pp. 55-72
    • Barrett-Connor, E.1    Grady, D.2
  • 14
    • 0027164529 scopus 로고
    • The effects of the menopause on insulin sensitivity, secretion and elimination in nonobese, healthy women
    • Walton C, Godsland IF, Proudler AJ, et al. 1993. The effects of the menopause on insulin sensitivity, secretion and elimination in nonobese, healthy women. Eur. J. Clin. Invest. 23:466-73
    • (1993) Eur. J. Clin. Invest. , vol.23 , pp. 466-73
    • Walton, C.1    Godsland, I.F.2    Proudler, A.J.3
  • 15
    • 25144495521 scopus 로고    scopus 로고
    • Is the estrogen controversy over? Deconstructing the Women's Health Initiative study: A critical evaluation of the evidence
    • Harman SM, Naftolin F, Brinton EA, et al. 2005. Is the estrogen controversy over? Deconstructing the Women's Health Initiative study: a critical evaluation of the evidence. Ann. NY Acad. Sci. 1052:43-56
    • (2005) Ann. NY Acad. Sci. , vol.1052 , pp. 43-56
    • Harman, S.M.1    Naftolin, F.2    Brinton, E.A.3
  • 16
    • 34548023930 scopus 로고    scopus 로고
    • Hormones and heart disease in women: The timing hypothesis
    • Barrett-Connor E. 2007. Hormones and heart disease in women: the timing hypothesis. Am. J. Epidemiol. 166:506-10
    • (2007) Am. J. Epidemiol. , vol.166 , pp. 506-10
    • Barrett-Connor, E.1
  • 17
    • 0015151724 scopus 로고
    • Proliferative endometrial response to theca-granulosa cell tumors
    • Gusberg SB, Kardon P. 1971. Proliferative endometrial response to theca-granulosa cell tumors. Am. J. Obstet. Gynecol. 111:633-43
    • (1971) Am. J. Obstet. Gynecol. , vol.111 , pp. 633-43
    • Gusberg, S.B.1    Kardon, P.2
  • 18
  • 19
    • 4444373076 scopus 로고    scopus 로고
    • Prevention of cancers of the breast, endometrium and ovary
    • Pike MC, Pearce CL, Wu AH. 2004. Prevention of cancers of the breast, endometrium and ovary. Oncogene 23:6379-91
    • (2004) Oncogene , vol.23 , pp. 6379-91
    • Pike, M.C.1    Pearce, C.L.2    Wu, A.H.3
  • 21
    • 0031240327 scopus 로고    scopus 로고
    • Mammary gland development and tumorigenesis in estrogen receptor knockout mice
    • Bocchinfuso WP, Korach KS. 1997. Mammary gland development and tumorigenesis in estrogen receptor knockout mice. J. Mammary Gland Biol. Neoplasia 2:323-34
    • (1997) J. Mammary Gland Biol. Neoplasia , vol.2 , pp. 323-34
    • Bocchinfuso, W.P.1    Korach, K.S.2
  • 22
    • 0033305438 scopus 로고    scopus 로고
    • Estrogen receptor null mice: What have we learned and where will they lead us?
    • Couse JF, Korach KS. 1999. Estrogen receptor null mice: What have we learned and where will they lead us? Endocr. Rev. 20:358-417
    • (1999) Endocr. Rev. , vol.20 , pp. 358-417
    • Couse, J.F.1    Korach, K.S.2
  • 24
    • 75649149550 scopus 로고    scopus 로고
    • Histological and molecular types of breast cancer: Is there a unifying taxonomy?
    • Weigelt B, Reis-Filho JS. 2009. Histological and molecular types of breast cancer: Is there a unifying taxonomy? Nat. Rev. Clin. Oncol. 6:718-30
    • (2009) Nat. Rev. Clin. Oncol. , vol.6 , pp. 718-30
    • Weigelt, B.1    Reis-Filho, J.S.2
  • 25
    • 0034680102 scopus 로고    scopus 로고
    • Molecular portraits of human breast tumours
    • Perou CM, Sorlie T, Eisen MB, et al. 2000. Molecular portraits of human breast tumours. Nature 406:747-52
    • (2000) Nature , vol.406 , pp. 747-52
    • Perou, C.M.1    Sorlie, T.2    Eisen, M.B.3
  • 26
    • 0000673542 scopus 로고
    • An ovarian hormone: Preliminary report on its localization, extraction and partial purification and action in test animals
    • Allen E, Doisy EA. 1923. An ovarian hormone: preliminary report on its localization, extraction and partial purification and action in test animals. JAMA 81:819-23
    • (1923) JAMA , vol.81 , pp. 819-23
    • Allen, E.1    Doisy, E.A.2
  • 27
    • 84965826780 scopus 로고
    • Hormonal pathogenesis of adenocarcinoma of the breast
    • Lacassagne A. 1936. Hormonal pathogenesis of adenocarcinoma of the breast. Am. J. Cancer 27:217-25
    • (1936) Am. J. Cancer , vol.27 , pp. 217-25
    • Lacassagne, A.1
  • 29
    • 0029991055 scopus 로고    scopus 로고
    • Nurses' Health Study: Log-incidence mathematical model of breast cancer incidence
    • Rosner B, Colditz GA. 1996. Nurses' Health Study: log-incidence mathematical model of breast cancer incidence. J. Natl. Cancer Inst. 88:359-64
    • (1996) J. Natl. Cancer Inst. , vol.88 , pp. 359-64
    • Rosner, B.1    Colditz, G.A.2
  • 31
    • 0025044624 scopus 로고
    • Breast cancer and combined oral contraceptives: Results from a multinational study
    • The WHO Collaborative Study of Neoplasia and Steroid Contraceptives
    • 1990. Breast cancer and combined oral contraceptives: results from a multinational study. The WHO Collaborative Study of Neoplasia and Steroid Contraceptives. Br. J. Cancer 61:110-19
    • (1990) Br. J. Cancer , vol.61 , pp. 110-19
  • 32
    • 0037830132 scopus 로고    scopus 로고
    • Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: The Women's Health Initiative randomized trial
    • Chlebowski RT, Hendrix SL, Langer RD, et al. 2003. Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women's Health Initiative randomized trial. JAMA 289:3243-53
    • (2003) JAMA , vol.289 , pp. 3243-53
    • Chlebowski, R.T.1    Hendrix, S.L.2    Langer, R.D.3
  • 33
    • 0030670385 scopus 로고    scopus 로고
    • Dissociation between steroid receptor expression and cell proliferation in the human breast
    • Clarke RB, Howell A, Potten CS, et al. 1997. Dissociation between steroid receptor expression and cell proliferation in the human breast. Cancer Res. 57:4987-91
    • (1997) Cancer Res. , vol.57 , pp. 4987-91
    • Clarke, R.B.1    Howell, A.2    Potten, C.S.3
  • 34
    • 46249125768 scopus 로고    scopus 로고
    • Conflicting evidence on the frequency of ESR1 amplification in breast cancer
    • Albertson DG. 2008. Conflicting evidence on the frequency of ESR1 amplification in breast cancer. Nat. Genet. 40:821-22
    • (2008) Nat. Genet. , vol.40 , pp. 821-22
    • Albertson, D.G.1
  • 35
    • 0032491774 scopus 로고    scopus 로고
    • Estrogen receptor expression in benign breast epithelium and breast cancer risk
    • Khan SA, Rogers MA, Khurana KK, et al. 1998. Estrogen receptor expression in benign breast epithelium and breast cancer risk. J. Natl. Cancer Inst. 90:37-42
    • (1998) J. Natl. Cancer Inst. , vol.90 , pp. 37-42
    • Khan, S.A.1    Rogers, M.A.2    Khurana, K.K.3
  • 36
    • 0032795728 scopus 로고    scopus 로고
    • Estrogen receptor-positive proliferating cells in the normal and precancerous breast
    • Shoker BS, Jarvis C, Clarke RB, et al. 1999. Estrogen receptor-positive proliferating cells in the normal and precancerous breast. Am. J. Pathol. 155:1811-15
    • (1999) Am. J. Pathol. , vol.155 , pp. 1811-15
    • Shoker, B.S.1    Jarvis, C.2    Clarke, R.B.3
  • 37
    • 36949059277 scopus 로고
    • Contrasting endocrine activities of cis and trans isomers in a series of substituted triphenylethylenes
    • Harper MJ, Walpole AL. 1966. Contrasting endocrine activities of cis and trans isomers in a series of substituted triphenylethylenes. Nature 212:87
    • (1966) Nature , vol.212 , pp. 87
    • Harper, M.J.1    Walpole, A.L.2
  • 38
    • 0037364074 scopus 로고    scopus 로고
    • Tamoxifen: A most unlikely pioneering medicine
    • Jordan VC. 2003. Tamoxifen: a most unlikely pioneering medicine. Nat. Rev. Drug Discov. 2:205-13
    • (2003) Nat. Rev. Drug Discov. , vol.2 , pp. 205-13
    • Jordan, V.C.1
  • 39
    • 0017102124 scopus 로고
    • The effects of estrogens and antiestrogens on hormone-responsive human breast cancer in long-term tissue culture
    • Lippman M, Bolan G, Huff K. 1976. The effects of estrogens and antiestrogens on hormone-responsive human breast cancer in long-term tissue culture. Cancer Res. 36:4595-601
    • (1976) Cancer Res. , vol.36 , pp. 4595-601
    • Lippman, M.1    Bolan, G.2    Huff, K.3
  • 40
    • 0016736721 scopus 로고
    • The effect of synthetic antioestrogens on the growth and biochemistry of rat mammary tumours
    • Nicholson RI, Golder MP. 1975. The effect of synthetic antioestrogens on the growth and biochemistry of rat mammary tumours. Eur. J. Cancer 11:571-79
    • (1975) Eur. J. Cancer , vol.11 , pp. 571-79
    • Nicholson, R.I.1    Golder, M.P.2
  • 41
    • 0017078344 scopus 로고
    • Effect of tamoxifen (ICI 46474) on initiation and growth of DMBA-induced rat mammary carcinomata
    • Jordan VC. 1976. Effect of tamoxifen (ICI 46474) on initiation and growth of DMBA-induced rat mammary carcinomata. Eur. J. Cancer 12:419-24
    • (1976) Eur. J. Cancer , vol.12 , pp. 419-24
    • Jordan, V.C.1
  • 42
    • 19344364880 scopus 로고    scopus 로고
    • Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials
    • Early Breast Cancer Trialists' Collaborative Group
    • Early Breast Cancer Trialists' Collaborative Group. 2005. Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet 365:1687-717
    • (2005) Lancet , vol.365 , pp. 1687-717
  • 43
    • 10344238569 scopus 로고    scopus 로고
    • Five versus more than five years of tamoxifen therapy for breast cancer patients with negative lymph nodes and estrogen receptor-positive tumors
    • Fisher B, Dignam J, Bryant J, et al. 1996. Five versus more than five years of tamoxifen therapy for breast cancer patients with negative lymph nodes and estrogen receptor-positive tumors. J. Natl. Cancer Inst. 88:1529-42
    • (1996) J. Natl. Cancer Inst. , vol.88 , pp. 1529-42
    • Fisher, B.1    Dignam, J.2    Bryant, J.3
  • 44
    • 0028287647 scopus 로고
    • Effects of tamoxifen on uterus and ovaries of post-menopausal women in a randomised breast cancer prevention trial
    • Kedar RP, Bourne TH, Powles TJ, et al. 1994. Effects of tamoxifen on uterus and ovaries of post-menopausal women in a randomised breast cancer prevention trial. Lancet 343:1318-21
    • (1994) Lancet , vol.343 , pp. 1318-21
    • Kedar, R.P.1    Bourne, T.H.2    Powles, T.J.3
  • 45
    • 0028212970 scopus 로고
    • Tamoxifen and bone metabolism in postmenopausal low-risk breast cancer patients: A randomized study
    • Kristensen B, Ejlertsen B, Dalgaard P, et al. 1994. Tamoxifen and bone metabolism in postmenopausal low-risk breast cancer patients: a randomized study. J. Clin. Oncol. 12:992-97
    • (1994) J. Clin. Oncol. , vol.12 , pp. 992-97
    • Kristensen, B.1    Ejlertsen, B.2    Dalgaard, P.3
  • 46
    • 0026585852 scopus 로고
    • Effects of tamoxifen on bone mineral density in post-menopausal women with breast cancer
    • Love RR, Mazess RB, Barden HS, et al. 1992. Effects of tamoxifen on bone mineral density in post-menopausal women with breast cancer. N. Engl. J. Med. 326:852-56
    • (1992) N. Engl. J. Med. , vol.326 , pp. 852-56
    • Love, R.R.1    Mazess, R.B.2    Barden, H.S.3
  • 47
    • 0027325734 scopus 로고
    • Cardiac and thromboembolic morbidity among postmenopausal women with early-stage breast cancer in a randomized trial of adjuvant tamoxifen
    • Rutqvist LE, Mattsson A. 1993. Cardiac and thromboembolic morbidity among postmenopausal women with early-stage breast cancer in a randomized trial of adjuvant tamoxifen. J. Natl. Cancer Inst. 85:1398-406
    • (1993) J. Natl. Cancer Inst. , vol.85 , pp. 1398-406
    • Rutqvist, L.E.1    Mattsson, A.2
  • 48
    • 0030941737 scopus 로고    scopus 로고
    • Coronary heart disease mortality and adjuvant tamoxifen therapy
    • Costantino JP, Kuller LH, Ives DG, et al. 1997. Coronary heart disease mortality and adjuvant tamoxifen therapy. J. Natl. Cancer Inst. 89:776-82
    • (1997) J. Natl. Cancer Inst. , vol.89 , pp. 776-82
    • Costantino, J.P.1    Kuller, L.H.2    Ives, D.G.3
  • 49
    • 0037464769 scopus 로고    scopus 로고
    • Overview of the main outcomes in breast-cancer prevention trials
    • Cuzick J, Powles T, Veronesi U, et al. 2003. Overview of the main outcomes in breast-cancer prevention trials. Lancet 361:296-300
    • (2003) Lancet , vol.361 , pp. 296-300
    • Cuzick, J.1    Powles, T.2    Veronesi, U.3
  • 50
    • 27944492407 scopus 로고    scopus 로고
    • Tamoxifen for the prevention of breast cancer: Current status of the National Surgical Adjuvant Breast and Bowel Project P-1 study
    • Fisher B, Costantino JP, Wickerham DL, et al. 2005. Tamoxifen for the prevention of breast cancer: current status of the National Surgical Adjuvant Breast and Bowel Project P-1 study. J. Natl. Cancer Inst. 97:1652-62
    • (2005) J. Natl. Cancer Inst. , vol.97 , pp. 1652-62
    • Fisher, B.1    Costantino, J.P.2    Wickerham, D.L.3
  • 51
    • 0033581212 scopus 로고    scopus 로고
    • Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: Results from a 3-year randomized clinical trial
    • Ettinger B, Black DM, Mitlak BH, et al. 1999. Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene: results from a 3-year randomized clinical trial. JAMA 282:637-45
    • (1999) JAMA , vol.282 , pp. 637-45
    • Ettinger, B.1    Black, D.M.2    Mitlak, B.H.3
  • 52
    • 0033575083 scopus 로고    scopus 로고
    • The effect of raloxifene on risk of breast cancer in postmenopausal women: Results from the MORE randomized trial
    • Cummings SR, Eckert S, Krueger KA, et al. 1999. The effect of raloxifene on risk of breast cancer in postmenopausal women: results from the MORE randomized trial. JAMA 281:2189-97
    • (1999) JAMA , vol.281 , pp. 2189-97
    • Cummings, S.R.1    Eckert, S.2    Krueger, K.A.3
  • 53
    • 33745876266 scopus 로고    scopus 로고
    • Effects of raloxifene on cardiovascular events and breast cancer in postmenopausal women
    • Barrett-Connor E, Mosca L, Collins P, et al. 2006. Effects of raloxifene on cardiovascular events and breast cancer in postmenopausal women. N. Engl. J. Med. 355:125-37
    • (2006) N. Engl. J. Med. , vol.355 , pp. 125-37
    • Barrett-Connor, E.1    Mosca, L.2    Collins, P.3
  • 54
    • 77953529620 scopus 로고    scopus 로고
    • Update of the national surgical adjuvant breast and bowel project study of tamoxifen and raloxifene (STAR) P-2 Trial: Preventing breast cancer
    • Vogel VG, Costantino JP, Wickerham DL, et al. 2010. Update of the National Surgical Adjuvant Breast and Bowel Project Study of Tamoxifen and Raloxifene (STAR) P-2 Trial: preventing breast cancer. Cancer Prev. Res. 3:696
    • (2010) Cancer Prev. Res. , vol.3 , pp. 696
    • Vogel, V.G.1    Costantino, J.P.2    Wickerham, D.L.3
  • 55
    • 0037501319 scopus 로고    scopus 로고
    • The estrogen receptor: A model for molecular medicine
    • Jensen EV, Jordan VC. 2003. The estrogen receptor: a model for molecular medicine. Clin. Cancer Res. 9:1980-89
    • (2003) Clin. Cancer Res. , vol.9 , pp. 1980-89
    • Jensen, E.V.1    Jordan, V.C.2
  • 56
    • 33751080415 scopus 로고    scopus 로고
    • Pure oestrogen antagonists for the treatment of advanced breast cancer
    • Howell A. 2006. Pure oestrogen antagonists for the treatment of advanced breast cancer. Endocr. Relat. Cancer 13:689-706
    • (2006) Endocr. Relat. Cancer , vol.13 , pp. 689-706
    • Howell, A.1
  • 57
    • 2442648038 scopus 로고    scopus 로고
    • Comparison of fulvestrant versus tamoxifen for the treatment of advanced breast cancer in postmenopausal women previously untreated with endocrine therapy: A multinational, double-blind, randomized trial
    • Howell A, Robertson JF, Abram P, et al. 2004. Comparison of fulvestrant versus tamoxifen for the treatment of advanced breast cancer in postmenopausal women previously untreated with endocrine therapy: a multinational, double-blind, randomized trial. J. Clin. Oncol. 22:1605-13
    • (2004) J. Clin. Oncol. , vol.22 , pp. 1605-13
    • Howell, A.1    Robertson, J.F.2    Abram, P.3
  • 58
    • 43249130208 scopus 로고    scopus 로고
    • Double-blind, randomized placebo controlled trial of fulves-trant compared with exemestane after prior nonsteroidal aromatase inhibitor therapy in postmenopausal women with hormone receptor-positive, advanced breast cancer: Results from EFECT
    • Chia S, Gradishar W, Mauriac L, et al. 2008. Double-blind, randomized placebo controlled trial of fulves-trant compared with exemestane after prior nonsteroidal aromatase inhibitor therapy in postmenopausal women with hormone receptor-positive, advanced breast cancer: results from EFECT. J. Clin. Oncol. 26:1664-70
    • (2008) J. Clin. Oncol. , vol.26 , pp. 1664-70
    • Chia, S.1    Gradishar, W.2    Mauriac, L.3
  • 59
    • 76749091057 scopus 로고    scopus 로고
    • Activity of fulvestrant 500 mg versus anastrozole 1 mg as first-line treatment for advanced breast cancer: Results from the FIRST study
    • Robertson JF, Llombart-Cussac A, Rolski J, et al. 2009. Activity of fulvestrant 500 mg versus anastrozole 1 mg as first-line treatment for advanced breast cancer: results from the FIRST study. J. Clin. Oncol. 27:4530-35
    • (2009) J. Clin. Oncol. , vol.27 , pp. 4530-35
    • Robertson, J.F.1    Llombart-Cussac, A.2    Rolski, J.3
  • 60
    • 0001464486 scopus 로고
    • Basic guides to the mechanism of estrogen action
    • Jensen EV, Jacobsen HI. 1962. Basic guides to the mechanism of estrogen action. Rec. Prog. Horm. Res. 18:387-414
    • (1962) Rec. Prog. Horm. Res. , vol.18 , pp. 387-414
    • Jensen, E.V.1    Jacobsen, H.I.2
  • 61
    • 0013913886 scopus 로고
    • A receptor molecule for estrogens: Isolation from the rat uterus and preliminary characterization
    • Toft D, Gorski J. 1966. A receptor molecule for estrogens: isolation from the rat uterus and preliminary characterization. Proc. Natl. Acad. Sci. USA 55:1574-81
    • (1966) Proc. Natl. Acad. Sci. USA , vol.55 , pp. 1574-81
    • Toft, D.1    Gorski, J.2
  • 62
    • 0022653964 scopus 로고
    • Human oestrogen receptor cDNA: Sequence, expression and homology to v-erb-A
    • Green S, Walter P, Kumar V, et al. 1986. Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A. Nature 320:134-39
    • (1986) Nature , vol.320 , pp. 134-39
    • Green, S.1    Walter, P.2    Kumar, V.3
  • 63
    • 0022473069 scopus 로고
    • Sequence and expression of human estrogen receptor complementary DNA
    • Greene GL, Gilna P, Waterfield M, et al. 1986. Sequence and expression of human estrogen receptor complementary DNA. Science 231:1150-54
    • (1986) Science , vol.231 , pp. 1150-54
    • Greene, G.L.1    Gilna, P.2    Waterfield, M.3
  • 64
    • 0035976638 scopus 로고    scopus 로고
    • Nuclear receptors and lipid physiology: Opening the X-files
    • Chawla A, Repa JJ, Evans RM, et al. 2001. Nuclear receptors and lipid physiology: opening the X-files. Science 294:1866-70
    • (2001) Science , vol.294 , pp. 1866-70
    • Chawla, A.1    Repa, J.J.2    Evans, R.M.3
  • 65
    • 0030579801 scopus 로고    scopus 로고
    • Cloning of a novel receptor expressed in rat prostate and ovary
    • Kuiper GG, Enmark E, Pelto-Huikko M, et al. 1996. Cloning of a novel receptor expressed in rat prostate and ovary. Proc. Natl. Acad. Sci. USA 93:5925-30
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5925-30
    • Kuiper, G.G.1    Enmark, E.2    Pelto-Huikko, M.3
  • 66
    • 0030771389 scopus 로고    scopus 로고
    • Human estrogen receptor β binds DNA in a manner similar to and dimerizes with estrogen receptor α
    • Pace P, Taylor J, Suntharalingam S, et al. 1997. Human estrogen receptor β binds DNA in a manner similar to and dimerizes with estrogen receptor α. J. Biol. Chem. 272:25832-38
    • (1997) J. Biol. Chem. , vol.272 , pp. 25832-38
    • Pace, P.1    Taylor, J.2    Suntharalingam, S.3
  • 67
    • 15444368857 scopus 로고    scopus 로고
    • Mechanisms of estrogen receptor signaling: Convergence of genomic and nongenomic actions on target genes
    • Bjornstrom L, Sjoberg M. 2005. Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes. Mol. Endocrinol. 19:833-42
    • (2005) Mol. Endocrinol. , vol.19 , pp. 833-42
    • Bjornstrom, L.1    Sjoberg, M.2
  • 68
    • 0031877301 scopus 로고    scopus 로고
    • C-Myc or cyclin D1 mimics estrogen effects on cyclin E-Cdk2 activation and cell cycle reentry
    • Prall OW, Rogan EM, Musgrove EA, et al. 1998. c-Myc or cyclin D1 mimics estrogen effects on cyclin E-Cdk2 activation and cell cycle reentry. Mol. Cell Biol. 18:4499-508
    • (1998) Mol. Cell Biol. , vol.18 , pp. 4499-508
    • Prall, O.W.1    Rogan, E.M.2    Musgrove, E.A.3
  • 69
    • 70449103609 scopus 로고    scopus 로고
    • An oestrogen-receptor-alpha-bound human chromatin interactome
    • Fullwood MJ, Liu MH, Pan YF, et al. 2009. An oestrogen-receptor-alpha- bound human chromatin interactome. Nature 462:58-64
    • (2009) Nature , vol.462 , pp. 58-64
    • Fullwood, M.J.1    Liu, M.H.2    Pan, Y.F.3
  • 70
    • 33750442923 scopus 로고    scopus 로고
    • Genome-wide analysis of estrogen receptor binding sites
    • Carroll JS, Meyer CA, Song J, et al. 2006. Genome-wide analysis of estrogen receptor binding sites. Nat. Genet. 38:1289-97
    • (2006) Nat. Genet. , vol.38 , pp. 1289-97
    • Carroll, J.S.1    Meyer, C.A.2    Song, J.3
  • 71
    • 33748679908 scopus 로고    scopus 로고
    • A cell-type-specific transcriptional network required for estrogen regulation of cyclin D1 and cell cycle progression in breast cancer
    • Eeckhoute J, Carroll JS, Geistlinger TR, et al. 2006. A cell-type-specific transcriptional network required for estrogen regulation of cyclin D1 and cell cycle progression in breast cancer. Genes Dev. 20:2513-26
    • (2006) Genes Dev. , vol.20 , pp. 2513-26
    • Eeckhoute, J.1    Carroll, J.S.2    Geistlinger, T.R.3
  • 72
    • 2442670465 scopus 로고    scopus 로고
    • About GATA3, HNF3A, and XBP1, three genes coexpressed with the oestrogen receptor-alpha gene (ESR1) in breast cancer
    • Lacroix M, Leclercq G. 2004. About GATA3, HNF3A, and XBP1, three genes coexpressed with the oestrogen receptor-alpha gene (ESR1) in breast cancer. Mol. Cell Endocrinol. 219:1-7
    • (2004) Mol. Cell Endocrinol. , vol.219 , pp. 1-7
    • Lacroix, M.1    Leclercq, G.2
  • 73
    • 34547731515 scopus 로고    scopus 로고
    • Nuclear receptor coregulators and human disease
    • Lonard DM, Lanz RB, O'Malley BW. 2007. Nuclear receptor coregulators and human disease. Endocr. Rev. 28:575-87
    • (2007) Endocr. Rev. , vol.28 , pp. 575-87
    • Lonard, D.M.1    Lanz, R.B.2    O'Malley, B.W.3
  • 74
    • 46749134863 scopus 로고    scopus 로고
    • Dynamics of estrogen receptor-mediated transcriptional activation of responsive genes in vivo: Apprehending transcription in four dimensions
    • Metivier R, Huet G, Gallais R, et al. 2008. Dynamics of estrogen receptor-mediated transcriptional activation of responsive genes in vivo: apprehending transcription in four dimensions. Adv. Exp. Med. Biol. 617:129-38
    • (2008) Adv. Exp. Med. Biol. , vol.617 , pp. 129-38
    • Metivier, R.1    Huet, G.2    Gallais, R.3
  • 75
    • 15544371000 scopus 로고    scopus 로고
    • Ligand control of coregulator recruitment to nuclear receptors
    • Nettles KW, Greene GL. 2005. Ligand control of coregulator recruitment to nuclear receptors. Annu. Rev. Physiol. 67:309-33
    • (2005) Annu. Rev. Physiol. , vol.67 , pp. 309-33
    • Nettles, K.W.1    Greene, G.L.2
  • 76
    • 0034650893 scopus 로고    scopus 로고
    • The coregulator exchange in transcriptional functions of nuclear receptors
    • Glass CK, Rosenfeld MG. 2000. The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev. 14:121-41
    • (2000) Genes Dev. , vol.14 , pp. 121-41
    • Glass, C.K.1    Rosenfeld, M.G.2
  • 77
    • 0042889568 scopus 로고    scopus 로고
    • The roles of protein-protein interactions and protein methylation in transcriptional activation by nuclear receptors and their coactivators
    • Stallcup MR, Kim JH, Teyssier C, et al. 2003. The roles of protein-protein interactions and protein methylation in transcriptional activation by nuclear receptors and their coactivators. J. Steroid Biochem. Mol. Biol. 85:139-45
    • (2003) J. Steroid Biochem. Mol. Biol. , vol.85 , pp. 139-45
    • Stallcup, M.R.1    Kim, J.H.2    Teyssier, C.3
  • 78
    • 0034612264 scopus 로고    scopus 로고
    • The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development
    • Xu J, Liao L, Ning G, et al. 2000. The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development. Proc. Natl. Acad. Sci. USA 97:6379-84
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 6379-84
    • Xu, J.1    Liao, L.2    Ning, G.3
  • 79
    • 0032549744 scopus 로고    scopus 로고
    • Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene
    • Xu J, Qiu Y, DeMayo FJ, et al. 1998. Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene. Science 279:1922-25
    • (1998) Science , vol.279 , pp. 1922-25
    • Xu, J.1    Qiu, Y.2    Demayo, F.J.3
  • 80
    • 0037470031 scopus 로고    scopus 로고
    • Differential SERM effects on corepressor binding dictate ERalpha activity in vivo
    • Webb P, Nguyen P, Kushner PJ. 2003. Differential SERM effects on corepressor binding dictate ERalpha activity in vivo. J. Biol. Chem. 278:6912-20
    • (2003) J. Biol. Chem. , vol.278 , pp. 6912-20
    • Webb, P.1    Nguyen, P.2    Kushner, P.J.3
  • 81
    • 0037192501 scopus 로고    scopus 로고
    • Molecular determinants for the tissue specificity of SERMs
    • Shang Y, Brown M. 2002. Molecular determinants for the tissue specificity of SERMs. Science 295:2465-68
    • (2002) Science , vol.295 , pp. 2465-68
    • Shang, Y.1    Brown, M.2
  • 82
    • 33744792310 scopus 로고    scopus 로고
    • Sensors and signals: A coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response
    • Rosenfeld MG, Lunyak VV, Glass CK. 2006. Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response. Genes Dev. 20:1405-28
    • (2006) Genes Dev. , vol.20 , pp. 1405-28
    • Rosenfeld, M.G.1    Lunyak, V.V.2    Glass, C.K.3
  • 83
    • 11744282298 scopus 로고    scopus 로고
    • Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes
    • Lavinsky RM, Jepsen K, Heinzel T, et al. 1998. Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes. Proc. Natl. Acad. Sci. USA 95:2920-25
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 2920-25
    • Lavinsky, R.M.1    Jepsen, K.2    Heinzel, T.3
  • 84
    • 0034664769 scopus 로고    scopus 로고
    • Combinatorial roles of the nuclear receptor corepressor in transcription and development
    • Jepsen K, Hermanson O, Onami TM, et al. 2000. Combinatorial roles of the nuclear receptor corepressor in transcription and development. Cell 102:753-63
    • (2000) Cell , vol.102 , pp. 753-63
    • Jepsen, K.1    Hermanson, O.2    Onami, T.M.3
  • 85
    • 22344435852 scopus 로고    scopus 로고
    • Cell cycle progression stimulated by tamoxifen-bound estrogen receptor-alpha and promoter-specific effects in breast cancer cells deficient in N-CoR and SMRT
    • Keeton EK, Brown M. 2005. Cell cycle progression stimulated by tamoxifen-bound estrogen receptor-alpha and promoter-specific effects in breast cancer cells deficient in N-CoR and SMRT. Mol. Endocrinol. 19:1543-54
    • (2005) Mol. Endocrinol. , vol.19 , pp. 1543-54
    • Keeton, E.K.1    Brown, M.2
  • 86
    • 0037388540 scopus 로고    scopus 로고
    • Expression analysis of estrogen receptor alpha coregula-tors in breast carcinoma: Evidence that NCOR1 expression is predictive of the response to tamoxifen
    • Girault I, Lerebours F, Amarir S, et al. 2003. Expression analysis of estrogen receptor alpha coregula-tors in breast carcinoma: evidence that NCOR1 expression is predictive of the response to tamoxifen. Clin. Cancer Res. 9:1259-66
    • (2003) Clin. Cancer Res. , vol.9 , pp. 1259-66
    • Girault, I.1    Lerebours, F.2    Amarir, S.3
  • 87
    • 34548248572 scopus 로고    scopus 로고
    • Oestrogen-receptor-mediated transcription and the influence of cofactors and chromatin state
    • Green KA, Carroll JS. 2007. Oestrogen-receptor-mediated transcription and the influence of cofactors and chromatin state. Nat. Rev. Cancer 7:713-22
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 713-22
    • Green, K.A.1    Carroll, J.S.2
  • 88
    • 0033974086 scopus 로고    scopus 로고
    • Expression levels of estrogen receptor-alpha, estrogen receptor-beta, coactivators, and corepressors in breast cancer
    • Kurebayashi J, Otsuki T, Kunisue H, et al. 2000. Expression levels of estrogen receptor-alpha, estrogen receptor-beta, coactivators, and corepressors in breast cancer. Clin. Cancer Res. 6:512-18
    • (2000) Clin. Cancer Res. , vol.6 , pp. 512-18
    • Kurebayashi, J.1    Otsuki, T.2    Kunisue, H.3
  • 89
    • 33745699885 scopus 로고    scopus 로고
    • Role of estrogen receptor alpha transcriptional coregulators in tamoxifen resistance in breast cancer
    • Girault I, Bieche I, Lidereau R. 2006. Role of estrogen receptor alpha transcriptional coregulators in tamoxifen resistance in breast cancer. Maturitas 54:342-51
    • (2006) Maturitas , vol.54 , pp. 342-51
    • Girault, I.1    Bieche, I.2    Lidereau, R.3
  • 90
    • 9144269004 scopus 로고    scopus 로고
    • Inverse relationship between ER-beta and SRC-1 predicts outcome in endocrine-resistant breast cancer
    • Myers E, Fleming FJ, Crotty TB, et al. 2004. Inverse relationship between ER-beta and SRC-1 predicts outcome in endocrine-resistant breast cancer. Br. J. Cancer 91:1687-93
    • (2004) Br. J. Cancer , vol.91 , pp. 1687-93
    • Myers, E.1    Fleming, F.J.2    Crotty, T.B.3
  • 91
    • 4544314561 scopus 로고    scopus 로고
    • High tumor incidence and activation of the PI3K/AKT pathway in transgenic mice define AIB1 as an oncogene
    • Torres-Arzayus MI, Font de Mora J, Yuan J, et al. 2004. High tumor incidence and activation of the PI3K/AKT pathway in transgenic mice define AIB1 as an oncogene. Cancer Cell 6:263-74
    • (2004) Cancer Cell , vol.6 , pp. 263-74
    • Torres-Arzayus, M.I.1    Font De Mora, J.2    Yuan, J.3
  • 92
    • 33947432483 scopus 로고    scopus 로고
    • Amplified in breast cancer 1 in human epidermal growth factor receptor-positive tumors of tamoxifen-treated breast cancer patients
    • Kirkegaard T, McGlynn LM, Campbell FM, et al. 2007. Amplified in breast cancer 1 in human epidermal growth factor receptor-positive tumors of tamoxifen-treated breast cancer patients. Clin. Cancer Res. 13:1405-11
    • (2007) Clin. Cancer Res. , vol.13 , pp. 1405-11
    • Kirkegaard, T.1    McGlynn, L.M.2    Campbell, F.M.3
  • 93
    • 0037234105 scopus 로고    scopus 로고
    • In vivo imaging of transcriptionally active estrogen receptors
    • Ciana P, Raviscioni M, Mussi P, et al. 2003. In vivo imaging of transcriptionally active estrogen receptors. Nat. Med. 9:82-86
    • (2003) Nat. Med. , vol.9 , pp. 82-86
    • Ciana, P.1    Raviscioni, M.2    Mussi, P.3
  • 94
    • 37449028688 scopus 로고    scopus 로고
    • Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month analysis of the ATAC trial
    • Forbes JF, Cuzick J, Buzdar A, et al. 2008. Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month analysis of the ATAC trial. Lancet. Oncol. 9:45-53
    • (2008) Lancet. Oncol. , vol.9 , pp. 45-53
    • Forbes, J.F.1    Cuzick, J.2    Buzdar, A.3
  • 95
    • 29544433211 scopus 로고    scopus 로고
    • A comparison of letrozole and tamoxifen in post-menopausal women with early breast cancer
    • Thurlimann B, Keshaviah A, Coates AS, et al. 2005. A comparison of letrozole and tamoxifen in post-menopausal women with early breast cancer. N. Engl. J. Med. 353:2747-57
    • (2005) N. Engl. J. Med. , vol.353 , pp. 2747-57
    • Thurlimann, B.1    Keshaviah, A.2    Coates, A.S.3
  • 96
    • 33846545851 scopus 로고    scopus 로고
    • Survival and safety of exemestane versus tamoxifen after 2-3 years' tamoxifen treatment (Intergroup Exemestane Study): A randomised controlled trial
    • Coombes RC, Kilburn LS, Snowdon CF, et al. 2007. Survival and safety of exemestane versus tamoxifen after 2-3 years' tamoxifen treatment (Intergroup Exemestane Study): a randomised controlled trial. Lancet 369:559-70
    • (2007) Lancet , vol.369 , pp. 559-70
    • Coombes, R.C.1    Kilburn, L.S.2    Snowdon, C.F.3
  • 97
    • 67349223542 scopus 로고    scopus 로고
    • Estrogen receptor beta in breast cancer-diagnostic and therapeutic implications
    • Hartman J, Strom A, Gustafsson JA. 2009. Estrogen receptor beta in breast cancer-diagnostic and therapeutic implications. Steroids 74:635-41
    • (2009) Steroids , vol.74 , pp. 635-41
    • Hartman, J.1    Strom, A.2    Gustafsson, J.A.3
  • 98
    • 39149113165 scopus 로고    scopus 로고
    • Development of the 21-gene assay and its application in clinical practice and clinical trials
    • Sparano JA, Paik S. 2008. Development of the 21-gene assay and its application in clinical practice and clinical trials. J. Clin. Oncol. 26:721-28
    • (2008) J. Clin. Oncol. , vol.26 , pp. 721-28
    • Sparano, J.A.1    Paik, S.2
  • 99


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