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Volumn 27, Issue 2, 2011, Pages 120-176

Amino acid-induced gene expression profiling in clonal β-cell line INS-1E cells

Author keywords

cell; Amino acid; Expression profiling; Metabolism

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; ALPHA 2 MACROGLOBULIN; AMPHIREGULIN; BAG 1 PROTEIN; CALCIUM CHANNEL Q TYPE; CERULOPLASMIN; CYSTATHIONINE GAMMA LYASE; CYTOCHROME P450 3A1; FIBROBLAST GROWTH FACTOR 21; FUCOSYLTRANSFERASE; GLUTAREDOXIN; HOMOCYSTEINE; INSULIN RECEPTOR; KRUPPEL LIKE FACTOR 2; LEUCINE; MELANOMA ANTIGEN 1; MESSENGER RNA; N ACETYLNEURAMINIC ACID; NICOTINAMIDE METHYLTRANSFERASE; PALMITOYL COENZYME A HYDROLASE; PROLINE; PROLINE RICH PROTEIN; PYRUVATE DEHYDROGENASE KINASE 2; SOMATOMEDIN BINDING PROTEIN 1; SYNAPTOTAGMIN; TENASCIN; TISSUE PLASMINOGEN ACTIVATOR; TRANSCRIPTION FACTOR GATA 4; UNINDEXED DRUG; VISININ;

EID: 79551576241     PISSN: 15207552     EISSN: 15207560     Source Type: Journal    
DOI: 10.1002/dmrr.1153     Document Type: Article
Times cited : (8)

References (55)
  • 1
    • 0034751632 scopus 로고    scopus 로고
    • The effect of chronic exposure to fatty acids on gene expression in clonal insulin-producing cells: studies using high density oligonucleotide microarray
    • Xiao J, Gregersen S, Kruhøffer M, Ørntoft TF, Hermansen K. The effect of chronic exposure to fatty acids on gene expression in clonal insulin-producing cells: studies using high density oligonucleotide microarray. Endocrinology 2001; 142: 4777-4784.
    • (2001) Endocrinology , vol.142 , pp. 4777-4784
    • Xiao, J.1    Gregersen, S.2    Kruhøffer, M.3    Ørntoft, T.F.4    Hermansen, K.5
  • 2
    • 34447555807 scopus 로고    scopus 로고
    • Stevioside improves pancreatic beta cell function during glucotoxicity via regulation of acetyl-CoA carboxylase
    • Chen J, Jeppesen P, Nordentoft I, Hermansen K. Stevioside improves pancreatic beta cell function during glucotoxicity via regulation of acetyl-CoA carboxylase. Am J Physiol 2007; 292: E1906-E1916.
    • (2007) Am J Physiol , vol.292
    • Chen, J.1    Jeppesen, P.2    Nordentoft, I.3    Hermansen, K.4
  • 3
    • 20444456317 scopus 로고    scopus 로고
    • Amino acid-dependent modulation of glucose metabolism in humans
    • Krebs M. Amino acid-dependent modulation of glucose metabolism in humans. Eur J Clin Invest 2005; 35: 351-354.
    • (2005) Eur J Clin Invest , vol.35 , pp. 351-354
    • Krebs, M.1
  • 4
    • 0033789795 scopus 로고    scopus 로고
    • Effect of long-term dietary protein intake on glucose metabolism in humans
    • Linn T, Santosa B, Gronemeyer D, et al. Effect of long-term dietary protein intake on glucose metabolism in humans. Diabetologia 2000; 43: 1257-1265.
    • (2000) Diabetologia , vol.43 , pp. 1257-1265
    • Linn, T.1    Santosa, B.2    Gronemeyer, D.3
  • 5
    • 0344687175 scopus 로고    scopus 로고
    • Processed meat intake and incidence of type 2 diabetes in younger and middle-aged women
    • Schulze MB, Manson JE, Willett WC, Hu FB. Processed meat intake and incidence of type 2 diabetes in younger and middle-aged women. Diabetologia 2003; 46: 1465-1473.
    • (2003) Diabetologia , vol.46 , pp. 1465-1473
    • Schulze, M.B.1    Manson, J.E.2    Willett, W.C.3    Hu, F.B.4
  • 6
    • 63449111894 scopus 로고    scopus 로고
    • A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance
    • Newgard CB, An J, Bain JR, et al. A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Cell Metab 2009; 9: 311-326.
    • (2009) Cell Metab , vol.9 , pp. 311-326
    • Newgard, C.B.1    An, J.2    Bain, J.R.3
  • 7
    • 77949267650 scopus 로고    scopus 로고
    • Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men
    • Tai ES, Tan ML, Stevens RD, et al. Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men. Diabetologia 2010; 53(4): 757-767.
    • (2010) Diabetologia , vol.53 , Issue.4 , pp. 757-767
    • Tai, E.S.1    Tan, M.L.2    Stevens, R.D.3
  • 8
    • 74749092317 scopus 로고    scopus 로고
    • Selective amino acid deficiency in patients with impaired glucose tolerance and type 2 diabetes
    • Menge BA, Schrader H, Ritter PR, et al. Selective amino acid deficiency in patients with impaired glucose tolerance and type 2 diabetes. Regul Pept 2010; 160(1-3): 75-80.
    • (2010) Regul Pept , vol.160 , Issue.1-3 , pp. 75-80
    • Menge, B.A.1    Schrader, H.2    Ritter, P.R.3
  • 9
    • 4243686213 scopus 로고
    • Amino Acid Metabolism and Therapy in Health and Nutritional Disease
    • Boca Raton, Florida, London: CRC
    • Cynober LA. Amino Acid Metabolism and Therapy in Health and Nutritional Disease. Boca Raton, Florida, London: CRC: 1995; 289-290.
    • (1995) , pp. 289-290
    • Cynober, L.A.1
  • 10
    • 79954451437 scopus 로고    scopus 로고
    • Proline and hydroxyproline metabolism: implications for animal and human nutrition
    • DOI: 10.1007/s00726-010-0715-z.
    • Wu G, Bazer FW, Burghardt RC, et al. Proline and hydroxyproline metabolism: implications for animal and human nutrition. Amino Acids 2010; DOI: 10.1007/s00726-010-0715-z.
    • (2010) Amino Acids
    • Wu, G.1    Bazer, F.W.2    Burghardt, R.C.3
  • 11
    • 0036313574 scopus 로고    scopus 로고
    • Mechanism of amino acid-induced skeletal muscle insulin resistance in humans
    • Krebs M, Krssak M, Bernroider E, et al. Mechanism of amino acid-induced skeletal muscle insulin resistance in humans. Diabetes 2002; 51: 599-605.
    • (2002) Diabetes , vol.51 , pp. 599-605
    • Krebs, M.1    Krssak, M.2    Bernroider, E.3
  • 12
    • 12444249578 scopus 로고    scopus 로고
    • Direct and indirect effects of amino acids on hepatic glucose metabolism in humans
    • Krebs M, Brehm A, Krssak M, et al. Direct and indirect effects of amino acids on hepatic glucose metabolism in humans. Diabetologia 2003; 46: 917-925.
    • (2003) Diabetologia , vol.46 , pp. 917-925
    • Krebs, M.1    Brehm, A.2    Krssak, M.3
  • 13
    • 0037164375 scopus 로고    scopus 로고
    • Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis
    • Wald DS, Law M, Morris JK. Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis. BMJ 2002; 325(7374): 1202.
    • (2002) BMJ , vol.325 , Issue.7374 , pp. 1202
    • Wald, D.S.1    Law, M.2    Morris, J.K.3
  • 14
    • 0026684554 scopus 로고
    • A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians
    • Stampfer MJ, Malinow MR, Willett WC, et al. A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians. JAMA 1992; 268(7): 877-881.
    • (1992) JAMA , vol.268 , Issue.7 , pp. 877-881
    • Stampfer, M.J.1    Malinow, M.R.2    Willett, W.C.3
  • 15
    • 0345375263 scopus 로고    scopus 로고
    • Hyperhomocysteinemia as a component of syndrome X
    • Oron-Herman M, Rosenthal T, Sela BA. Hyperhomocysteinemia as a component of syndrome X. Metabolism 2003; 52(11): 1491-1495.
    • (2003) Metabolism , vol.52 , Issue.11 , pp. 1491-1495
    • Oron-Herman, M.1    Rosenthal, T.2    Sela, B.A.3
  • 16
    • 14544296715 scopus 로고    scopus 로고
    • Homocysteine thiolactone inhibits insulin stimulated DNA and protein synthesis: possible role of mitogen-activated protein kinase (MAPK), glycogen synthase kinase-3 (GSK-3) and p70 S6K phosphorylation
    • Najib S, Sanchez-Margalet V. Homocysteine thiolactone inhibits insulin stimulated DNA and protein synthesis: possible role of mitogen-activated protein kinase (MAPK), glycogen synthase kinase-3 (GSK-3) and p70 S6K phosphorylation. J Mol Endocrinol 2005; 34(1): 119-126.
    • (2005) J Mol Endocrinol , vol.34 , Issue.1 , pp. 119-126
    • Najib, S.1    Sanchez-Margalet, V.2
  • 18
    • 28444466562 scopus 로고    scopus 로고
    • Hyperhomocysteinemia correlates with insulin resistance and low-grade systemic inflammation in obese prepubertal children
    • Martos R, Valle M, Morales R, Cañete R, Gavilan MI, Sánchez-Margalet V. Hyperhomocysteinemia correlates with insulin resistance and low-grade systemic inflammation in obese prepubertal children. Metabolism 2006; 55(1): 72-77.
    • (2006) Metabolism , vol.55 , Issue.1 , pp. 72-77
    • Martos, R.1    Valle, M.2    Morales, R.3    Cañete, R.4    Gavilan, M.I.5    Sánchez-Margalet, V.6
  • 19
    • 14844296371 scopus 로고    scopus 로고
    • New insights into amino acid metabolism, β-cell function and diabetes
    • Newsholme P, Brennan L, Rubi B, Maechler P. New insights into amino acid metabolism, β-cell function and diabetes. Clin Sci 2005; 108: 185-194.
    • (2005) Clin Sci , vol.108 , pp. 185-194
    • Newsholme, P.1    Brennan, L.2    Rubi, B.3    Maechler, P.4
  • 20
    • 0029828189 scopus 로고    scopus 로고
    • Mechanisms of amino acid-induced insulin secretion from the glucose-responsive BRIN-BD11 pancreatic β-cell line
    • McClenaghan NH, Barnett CR, O'Harte FPM, Flatt PR. Mechanisms of amino acid-induced insulin secretion from the glucose-responsive BRIN-BD11 pancreatic β-cell line. J Endocrinol 1996; 15: 349-357.
    • (1996) J Endocrinol , vol.15 , pp. 349-357
    • McClenaghan, N.H.1    Barnett, C.R.2    O'Harte, F.P.M.3    Flatt, P.R.4
  • 21
    • 67649268097 scopus 로고    scopus 로고
    • Dose- and glucose- dependent effects of amino acids on insulin secretion from isolated mouse islets and clonal INS-1E beta-cells
    • Liu Z, Jeppesen PB, Gregersen S, Chen X, Hermansen K. Dose- and glucose- dependent effects of amino acids on insulin secretion from isolated mouse islets and clonal INS-1E beta-cells. Rev Diabet Stud 2008; 5(4): 232-244.
    • (2008) Rev Diabet Stud , vol.5 , Issue.4 , pp. 232-244
    • Liu, Z.1    Jeppesen, P.B.2    Gregersen, S.3    Chen, X.4    Hermansen, K.5
  • 22
    • 0035202886 scopus 로고    scopus 로고
    • Chronic exposure to high leucine impairs glucose-induced insulin release by lowering the ATP-to-ADP ratio
    • Anello M, Ucciardello V, Piro S, et al. Chronic exposure to high leucine impairs glucose-induced insulin release by lowering the ATP-to-ADP ratio. Am J Physiol Endocrinol Metab 2001; 281(5): E1082-E1087.
    • (2001) Am J Physiol Endocrinol Metab , vol.281 , Issue.5
    • Anello, M.1    Ucciardello, V.2    Piro, S.3
  • 23
    • 33644753928 scopus 로고    scopus 로고
    • Leucine regulation of glucokinase and ATP synthase sensitizes glucose-induced insulin secretion in pancreatic beta cells
    • Yang J, Wong RK, Park M, et al. Leucine regulation of glucokinase and ATP synthase sensitizes glucose-induced insulin secretion in pancreatic beta cells. Diabetes 2006; 55: 193-201.
    • (2006) Diabetes , vol.55 , pp. 193-201
    • Yang, J.1    Wong, R.K.2    Park, M.3
  • 25
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001; 29(9): e45.
    • (2001) Nucleic Acids Res , vol.29 , Issue.9
    • Pfaffl, M.W.1
  • 26
    • 33745612095 scopus 로고    scopus 로고
    • Pvclust: an R package for assessing the uncertainty in hierarchical clustering
    • Ryota Suzuki, Hidetoshi Shimodaira. Pvclust: an R package for assessing the uncertainty in hierarchical clustering. Bioinformatics 2006; 22(12): 1540-1542.
    • (2006) Bioinformatics , vol.22 , Issue.12 , pp. 1540-1542
    • Ryota, S.1    Shimodaira, H.2
  • 27
    • 0033982936 scopus 로고    scopus 로고
    • KEGG: Kyoto encyclopedia of genes and genomes
    • Kanehisa M, Goto S. KEGG: Kyoto encyclopedia of genes and genomes. Nucleic Acids Res 2000; 28: 27-30.
    • (2000) Nucleic Acids Res , vol.28 , pp. 27-30
    • Kanehisa, M.1    Goto, S.2
  • 28
    • 0034069495 scopus 로고    scopus 로고
    • Gene ontology: tool for the unification of biology. The Gene Ontology Consortium
    • Ashburner M, Ball CA, Blake JA, et al. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet 2000; 25: 25-29.
    • (2000) Nat Genet , vol.25 , pp. 25-29
    • Ashburner, M.1    Ball, C.A.2    Blake, J.A.3
  • 29
    • 27844494151 scopus 로고    scopus 로고
    • L-Alanine induces changes in metabolic and signal transduction gene expression in a clonal rat pancreatic beta-cell line and protects from pro-inflammatory cytokine-induced apoptosis
    • Cunningham GA, McClenaghan NH, Flatt PR, Newsholme P. L-Alanine induces changes in metabolic and signal transduction gene expression in a clonal rat pancreatic beta-cell line and protects from pro-inflammatory cytokine-induced apoptosis. Clin Sci (Lond) 2005; 109(5): 447-455.
    • (2005) Clin Sci (Lond) , vol.109 , Issue.5 , pp. 447-455
    • Cunningham, G.A.1    McClenaghan, N.H.2    Flatt, P.R.3    Newsholme, P.4
  • 30
    • 33749861808 scopus 로고    scopus 로고
    • Glutamine regulates expression of key transcription factor, signal transduction, metabolic gene, and protein expression in a clonal pancreatic beta-cell line
    • Corless M, Kiely A, McClenaghan NH, Flatt PR, Newsholme P. Glutamine regulates expression of key transcription factor, signal transduction, metabolic gene, and protein expression in a clonal pancreatic beta-cell line. J Endocrinol 2006; 190(3): 719-727.
    • (2006) J Endocrinol , vol.190 , Issue.3 , pp. 719-727
    • Corless, M.1    Kiely, A.2    McClenaghan, N.H.3    Flatt, P.R.4    Newsholme, P.5
  • 31
    • 0347318052 scopus 로고    scopus 로고
    • The AMP-activated protein kinase cascade F a unifying system for energy control
    • Carling D. The AMP-activated protein kinase cascade F a unifying system for energy control. Trends Biochem Sci 2004; 29: 18-24.
    • (2004) Trends Biochem Sci , vol.29 , pp. 18-24
    • Carling, D.1
  • 32
    • 20344386733 scopus 로고    scopus 로고
    • Transcriptomics and metabolomics of dietary leucine excess
    • Matsuzaki K, Kato H, Sakai R, Toue S, Amao M, Kimura T. Transcriptomics and metabolomics of dietary leucine excess. J Nutr 2005; 135(6 Suppl): 1571S-1575S.
    • (2005) J Nutr , vol.135 , Issue.6 SUPPL.
    • Matsuzaki, K.1    Kato, H.2    Sakai, R.3    Toue, S.4    Amao, M.5    Kimura, T.6
  • 33
    • 33847722655 scopus 로고    scopus 로고
    • β-Cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment
    • Brunham LR, Kruit JK, Pape TD, et al. β-Cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment. Nat Med 2007; 13: 340-347.
    • (2007) Nat Med , vol.13 , pp. 340-347
    • Brunham, L.R.1    Kruit, J.K.2    Pape, T.D.3
  • 34
    • 77952406884 scopus 로고    scopus 로고
    • Carriers of loss-of-function mutations in ABCA1 display pancreatic beta-cell dysfunction
    • Vergeer M, Brunham LR, Koetsveld J, et al. Carriers of loss-of-function mutations in ABCA1 display pancreatic beta-cell dysfunction. Diabetes Care 2010; 33(4): 869-874.
    • (2010) Diabetes Care , vol.33 , Issue.4 , pp. 869-874
    • Vergeer, M.1    Brunham, L.R.2    Koetsveld, J.3
  • 36
    • 63049105151 scopus 로고    scopus 로고
    • Hydrogen sulfide and the vasculature: a novel vasculoprotective entity and regulator of nitric oxide bioavailability?
    • Whiteman M, Moore PK. Hydrogen sulfide and the vasculature: a novel vasculoprotective entity and regulator of nitric oxide bioavailability? J Cell Mol Med 2009; 13(3): 488-507.
    • (2009) J Cell Mol Med , vol.13 , Issue.3 , pp. 488-507
    • Whiteman, M.1    Moore, P.K.2
  • 37
    • 54949084607 scopus 로고    scopus 로고
    • 2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase
    • 2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase. Science 2008; 322(5901): 587-590.
    • (2008) Science , vol.322 , Issue.5901 , pp. 587-590
    • Yang, G.1    Wu, L.2    Jiang, B.3
  • 39
    • 0032548919 scopus 로고    scopus 로고
    • Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE
    • Wang S, Miura M, Jung YK, Zhu H, Li E, Yuan J. Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE. Cell 1998; 92: 501-509.
    • (1998) Cell , vol.92 , pp. 501-509
    • Wang, S.1    Miura, M.2    Jung, Y.K.3    Zhu, H.4    Li, E.5    Yuan, J.6
  • 40
    • 33646175602 scopus 로고    scopus 로고
    • Enhanced bacterial clearance and sepsis resistance in caspase-12 deficient mice
    • Saleh MMJC, Wolinski MK, Bensinger SJ, et al. Enhanced bacterial clearance and sepsis resistance in caspase-12 deficient mice. Nature 2006; 440: 1064-1068.
    • (2006) Nature , vol.440 , pp. 1064-1068
    • Saleh, M.M.J.C.1    Wolinski, M.K.2    Bensinger, S.J.3
  • 41
    • 0036683653 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding proteins: structure, function and regulation
    • Ramji DP, Foka P. CCAAT/enhancer-binding proteins: structure, function and regulation. Biochem J 2002; 365(Pt 3): 561-575.
    • (2002) Biochem J , vol.365 , Issue.PART 3 , pp. 561-575
    • Ramji, D.P.1    Foka, P.2
  • 42
    • 0032947501 scopus 로고    scopus 로고
    • Hypoglycemia and impaired hepatic glucose production in mice with a deletion of the C/EBPβ gene
    • Liu S, Croninger C, Arizmendi C, et al. Hypoglycemia and impaired hepatic glucose production in mice with a deletion of the C/EBPβ gene. J Clin Invest 1999; 103: 207-213.
    • (1999) J Clin Invest , vol.103 , pp. 207-213
    • Liu, S.1    Croninger, C.2    Arizmendi, C.3
  • 43
    • 55649124531 scopus 로고    scopus 로고
    • Leucine, when ingested with glucose, synergistically stimulates insulin secretion and lowers blood glucose
    • Kalogeropoulou D, Lafave L, Schweim K, Gannon MC, Nuttall FQ. Leucine, when ingested with glucose, synergistically stimulates insulin secretion and lowers blood glucose. Metabolism 2008; 57(12): 1747-1752.
    • (2008) Metabolism , vol.57 , Issue.12 , pp. 1747-1752
    • Kalogeropoulou, D.1    Lafave, L.2    Schweim, K.3    Gannon, M.C.4    Nuttall, F.Q.5
  • 44
    • 1842292177 scopus 로고    scopus 로고
    • Pancreatic beta-cell-specific repression of insulin gene transcription by CCAAT/enhancer-binding protein beta. Inhibitory interactions with basic helix-loop-helix transcription factor E47
    • Lu M, Seufert J, Habener JF. Pancreatic beta-cell-specific repression of insulin gene transcription by CCAAT/enhancer-binding protein beta. Inhibitory interactions with basic helix-loop-helix transcription factor E47. J Biol Chem 1997; 272: 28349-28359.
    • (1997) J Biol Chem , vol.272 , pp. 28349-28359
    • Lu, M.1    Seufert, J.2    Habener, J.F.3
  • 45
    • 0032103208 scopus 로고    scopus 로고
    • Differential expression of the insulin gene transcriptional repressor CCAAT/enhancer-binding protein beta and transactivator islet duodenum homeobox-1 in rat pancreatic beta cells during the development of diabetes mellitus
    • Seufert J, Weir GC, Habener JF. Differential expression of the insulin gene transcriptional repressor CCAAT/enhancer-binding protein beta and transactivator islet duodenum homeobox-1 in rat pancreatic beta cells during the development of diabetes mellitus. J Clin Invest 1998; 101: 2528-2539.
    • (1998) J Clin Invest , vol.101 , pp. 2528-2539
    • Seufert, J.1    Weir, G.C.2    Habener, J.F.3
  • 46
    • 67349121773 scopus 로고    scopus 로고
    • Role of the transcriptional factor C/EBP beta in free fatty acid-elicited beta-cell failure
    • Plaisance V, Perret V, Favre D, et al.Role of the transcriptional factor C/EBP beta in free fatty acid-elicited beta-cell failure. Mol Cell Endocrinol 2009; 305(1-2): 47-55.
    • (2009) Mol Cell Endocrinol , vol.305 , Issue.1-2 , pp. 47-55
    • Plaisance, V.1    Perret, V.2    Favre, D.3
  • 47
    • 40949116757 scopus 로고    scopus 로고
    • The repression of IRS2 gene by ATF3, a stress-inducible gene, contributes to pancreatic beta-cell apoptosis
    • Li D, Yin X, Zmuda EJ, Wolford CC, Dong X, White MF, Hai T. The repression of IRS2 gene by ATF3, a stress-inducible gene, contributes to pancreatic beta-cell apoptosis. Diabetes 2008; 57: 635-644.
    • (2008) Diabetes , vol.57 , pp. 635-644
    • Li, D.1    Yin, X.2    Zmuda, E.J.3    Wolford, C.C.4    Dong, X.5    White, M.F.6    Hai, T.7
  • 48
    • 33845289819 scopus 로고    scopus 로고
    • Mechanisms underlying regulation of the expression and activities of the mammalian pyruvate dehydrogenase kinases
    • Sugden MC, Holness MJ. Mechanisms underlying regulation of the expression and activities of the mammalian pyruvate dehydrogenase kinases. Arch Physiol Biochem 2006; 112(3): 139-149.
    • (2006) Arch Physiol Biochem , vol.112 , Issue.3 , pp. 139-149
    • Sugden, M.C.1    Holness, M.J.2
  • 49
    • 0034064334 scopus 로고    scopus 로고
    • Beta-cell mitochondria in the regulation of insulin secretion: a new culprit in type II diabetes
    • Wollheim CB. Beta-cell mitochondria in the regulation of insulin secretion: a new culprit in type II diabetes. Diabetologia 2000; 43(3): 265-277.
    • (2000) Diabetologia , vol.43 , Issue.3 , pp. 265-277
    • Wollheim, C.B.1
  • 50
    • 0010991077 scopus 로고    scopus 로고
    • Glucose-fatty acid cycle to inhibit glucose utilization and oxidation is not operative in fatty acid cultured islets
    • Liu YQ, Tornheim K, Leahy JL. Glucose-fatty acid cycle to inhibit glucose utilization and oxidation is not operative in fatty acid cultured islets. Diabetes 1999; 48: 1747-1753.
    • (1999) Diabetes , vol.48 , pp. 1747-1753
    • Liu, Y.Q.1    Tornheim, K.2    Leahy, J.L.3
  • 51
    • 1542379983 scopus 로고    scopus 로고
    • Chronic high glucose lowers pyruvate dehydrogenase activity in islets through enhanced production of long chain acyl-CoA: prevention of impaired glucose oxidation by enhanced pyruvate recycling through the malate pyruvate shuttle
    • Liu YQ, Moibi JA, Leahy JL. Chronic high glucose lowers pyruvate dehydrogenase activity in islets through enhanced production of long chain acyl-CoA: prevention of impaired glucose oxidation by enhanced pyruvate recycling through the malate pyruvate shuttle. J Biol Chem 2004; 279: 7470-7475.
    • (2004) J Biol Chem , vol.279 , pp. 7470-7475
    • Liu, Y.Q.1    Moibi, J.A.2    Leahy, J.L.3
  • 52
    • 33646137142 scopus 로고    scopus 로고
    • Regulation of PDK mRNA by high fatty acid and glucose in pancreatic islets
    • Xu J, Han J, Epstein PN, Liu YQ. Regulation of PDK mRNA by high fatty acid and glucose in pancreatic islets. Biochem Biophys Res Commun 2006; 344(3): 827-833.
    • (2006) Biochem Biophys Res Commun , vol.344 , Issue.3 , pp. 827-833
    • Xu, J.1    Han, J.2    Epstein, P.N.3    Liu, Y.Q.4
  • 53
    • 0029072580 scopus 로고
    • Very long chain and long chain acyl-CoA thioesterases in rat liver mitochondria. Identification, purification, characterization, and induction by peroxisome proliferators
    • Svensson LT, Alexson SE, Hiltunen JK. Very long chain and long chain acyl-CoA thioesterases in rat liver mitochondria. Identification, purification, characterization, and induction by peroxisome proliferators. J Biol Chem 1995; 270: 12177-12183.
    • (1995) J Biol Chem , vol.270 , pp. 12177-12183
    • Svensson, L.T.1    Alexson, S.E.2    Hiltunen, J.K.3
  • 54
    • 0036138306 scopus 로고    scopus 로고
    • The role acyl-CoA thioesterases play in mediating intracellular lipid metabolism
    • Hunt MC, Alexson SEH. The role acyl-CoA thioesterases play in mediating intracellular lipid metabolism. Prog Lipid Res 2002; 41(2): 99-130.
    • (2002) Prog Lipid Res , vol.41 , Issue.2 , pp. 99-130
    • Hunt, M.C.1    Alexson, S.E.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.