Akt-FOXO3a signaling axis dysregulation in human oral squamous cell carcinoma and potent efficacy of FOXO3a-targeted gene therapy

Oral Oncology

Volumn 47, Issue 1, 2011, Pages 16-21

  Fang, Liang ^a   Wang, Huimng ^a   Zhou, Lin ^b   Yu, Da ^b  

^a ZHEJIANG UNIVERSITY   (China)

^b BEIJING HOSPITAL   (China)

Author keywords

Akt; Apoptosis; Cell cycle; FOXO3a; Gene therapy; Oral squamous cell carcinoma (OSCC)

Indexed keywords

BIM PROTEIN; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; PROTEIN KINASE B; PROTEIN P27; TRANSCRIPTION FACTOR FKHRL1;

ADULT; AGED; APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; ENZYME ACTIVITY; FEMALE; GENE THERAPY; HUMAN; HUMAN TISSUE; IMMUNOPATHOLOGY; MAJOR CLINICAL STUDY; MALE; ORAL SQUAMOUS CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA;

ADULT; AGED; ANIMALS; APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CELL DIVISION; CELL LINE, TUMOR; CELL PROLIFERATION; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE THERAPY; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MIDDLE AGED; MOUTH NEOPLASMS; NEOPLASM PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 79551512857     PISSN: 13688375     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2010.10.010     Document Type: Article

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