Metastasis-associated protein 1 enhances angiogenesis by stabilization of HIF-1α

Oncology Reports

Volumn 16, Issue 4, 2006, Pages 929-935

  Moon, Hyo Eun ^a   Cheon, Hwanju ^a   Chun, Kwang Hoon ^b   Lee, Seung Ki ^b   Kim, Yong Sik ^c   Jung, Bo Kyung ^b   Park, Jeong Ae ^b   Kim, Se Hee ^b   Jeong, Joo Won ^d   Lee, Myung Shik ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Seoul National University   (South Korea)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^d Kyung Hee University Hospital   (South Korea)

Author keywords

Angiogenesis; HIF 1 ; MTA1; Stabilization

Indexed keywords

COLLAGEN; GLUTATHIONE TRANSFERASE; HIF1A PROTEIN, HUMAN; HISTONE DEACETYLASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LAMININ; MATRIGEL; MTA1 PROTEIN, HUMAN; PROTEOGLYCAN; REPRESSOR PROTEIN;

ARTICLE; CHEMISTRY; CULTURE MEDIUM; DRUG COMBINATION; GENETIC TRANSCRIPTION; HUMAN; IMMUNOPRECIPITATION; METABOLISM; METASTASIS; NEOVASCULARIZATION (PATHOLOGY); TRANSACTIVATION; TUMOR CELL LINE;

CELL LINE, TUMOR; COLLAGEN; CULTURE MEDIA, CONDITIONED; DRUG COMBINATIONS; GLUTATHIONE TRANSFERASE; HISTONE DEACETYLASES; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOPRECIPITATION; LAMININ; NEOPLASM METASTASIS; NEOVASCULARIZATION, PATHOLOGIC; PROTEOGLYCANS; REPRESSOR PROTEINS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION, GENETIC;

EID: 35148873417     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.16.4.929     Document Type: Article

References (23)

1. Toh Y, Pencil SD and Nicolson GL: A novel candidate metastasisassociated gene, mta1, differentially expressed in highly metastatic mammary adenocarcinoma cell lines. cDNA cloning, expression and protein analyses. J Biol Chem 269: 22958-22963, 1994.
2. Toh Y, Oki E, Oda S, Tokunaga E, Ohno S, Maehara Y, Nicolson GL and Sugimachi K: Overexpression of the MTA1 gene in gastrointestinal carcinomas: correlation with invasion and metastasis. Int J Cancer 74: 459-463, 1997. (Pubitemid 27400170)
3. Hofer MD, Kuefer R, Varambally S, Li H, Ma J, Shapiro GI, Gschwend JE, Hautmann RE, Sanda MG, Giehl K, Menke A, Chinnaiyan AM and Rubin MA: The role of metastasis-associated protein 1 in prostate cancer progression. Cancer Res 64: 825-829, 2004. (Pubitemid 38176879)
4. Mahoney MG, Simpson A, Jost M, Noe M, Kari C, Pepe D, Choi YW, Uitto J and Rodeck U: Metastasis-associated protein (MTA) 1 enhances migration, invasion and anchorage-independent survival of immortalized human keratinocytes. Oncogene 21: 2161-2170, 2002. (Pubitemid 34311370)
5. Yao YL and Yang WM: The metastasis-associated proteins 1 and 2 form distinct protein complexes with histone deacetylase activity. J Biol Chem 278: 42560-42568, 2003.
6. Xue Y, Wong J, Moreno GT, Young MK and Wang W: NURD, a novel complex with both ATP-dependent chromatinremodeling and histone deacetylase activities. Mol Cell 2: 851-861, 1998. (Pubitemid 128378992)
7. Bowen NJ, Fujita N, Kajita M and Wade PA: Mi-2/NuRD: multiple complexes for many purposes. Biochim Biophys Acta 1677: 52-57, 2004. (Pubitemid 38327088)
8. Luo J, Su F, Chen D, Shiloh A and Gu W: Deacetylation of p53 modulates its effect on cell growth and apoptosis. Nature 408: 377-381, 2000.
9. Kim MS, Kwon HJ, Lee YM, Baek JH, Jang JE, Lee SW, Moon EJ, Kim HS, Lee SK, Chung HY, Kim CW and Kim KW: Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes. Nat Med 7: 437-443, 2001. (Pubitemid 32298546)
10. Jeong JW, Bae MK, Ahn MY, Kim SH, Sohn TK, Bae MH, Yoo MA, Song EJ, Lee KJ and Kim KW: Regulation and destabilization of HIF-1α by ARD1-mediated acetylation. Cell 111: 709-720, 2002. (Pubitemid 35441252)
11. Kim SH, Park JA, Kim JH, Lee JW, Seo JH, Jung BK, Chun KH, Jeong JW, Bae MK and Kim KW: Characterization of ARD1 variants in mammalian cells. Biochem Biophys Res Commun 340: 422-427, 2005.
12. Kim KR, Moon HE and Kim KW: Hypoxia-induced angiogenesis in human hepatocellular carcinoma. J Mol Med 80: 703-714, 2002.
13. 2-regulated prolyl hydroxylation. Science 292: 468-472, 2001.
14. Ohh M, Park CW, Ivan M, Hoffman MA, Kim TY, Huang LE, Pavletich N, Chau V and Kaelin WG: Ubiquitination of hypoxiainducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein. Nat Cell Biol 2: 423-427, 2000.
15. Moon EJ, Jeong CH, Jeong JW, Kim KR, Yu DY, Murakami S, Kim CW and Kim KW: Hepatitis B virus X protein induces angiogenesis by stabilizing hypoxia-inducible factor-1α. FASEB J 18: 382-384, 2004.
16. Tammela T, Enholm B, Alitalo K and Paavonen K: The biology of vascular endothelial growth factors. Cardiovasc Res 65: 550-563, 2005. (Pubitemid 40138976)
17. Krishnamachary B, Berg-Dixon S, Kelly B, Agani F, Feldser D, Ferreira G, Iyer N, La Rusch J, Pak B, Taghavi P and Semenza GL: Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1. Cancer Res 63: 1138-1143, 2003. (Pubitemid 36278449)
18. Mishra SK, Mazumdar A, Vadlamudi RK, Li F, Wang RA, Yu W, Jordan VC, Santen RJ and Kumar R: MICoA, a novel metastasis-associated protein 1 (MTA1) interacting protein coactivator, regulates estrogen receptor-alpha transactivation functions. J Biol Chem 278: 19209-19219, 2003. (Pubitemid 36799312)
19. Talukder AH, Gururaj A, Mishra SK, Vadlamudi RK and Kumar R: Metastasis-associated protein 1 interacts with NRIF3, an estrogen-inducible nuclear receptor coregulator. Mol Cell Biol 24: 6581-6591, 2004. (Pubitemid 38944339)
20. Brahimi-Horn C, Mazure N and Pouyssegur J: Signalling via the hypoxia-inducible factor-1alpha requires multiple post-translational modifications. Cell Signal 17: 1-9, 2005. (Pubitemid 39286774)
21. Bilton R, Mazure N, Trottier E, Hattab M, Dery MA, Richard DE, Pouyssegur J and Brahimi-Horn MC: Arrest-defective-1 protein, an acetyltransferase, does not alter stability of hypoxia-inducible factor (HIF)-1alpha and is not induced by hypoxia or HIF. J Biol Chem 280: 31132-31140, 2005. (Pubitemid 41291849)
22. Murray-Rust TA, Oldham NJ, Hewitson KS and Schofield CJ: Purified recombinant hARD1 does not catalyse acetylation of Lys(532) of HIF-1alpha fragments in vitro. FEBS Lett (In press).
23. Yoo YG, Kong G and Lee MO: Metastasis-associated protein 1 enhances stability of hypoxia-inducible factor-1alpha protein by recruiting histone deacetylase 1. EMBO J 25: 1231-1241, 2006.