High-level expression by tissue/cancer-specific promoter with strict specificity using a single-adenoviral vector

Nucleic Acids Research

Volumn 39, Issue 2, 2011, Pages

  Kanegae, Yumi ^a   Terashima, Miho ^a   Kondo, Saki ^a   Fukuda, Hiromitsu ^a   Maekawa, Aya ^a   Pei, Zheng ^a   Saito, Izumu ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ALPHA FETOPROTEIN; CIRCULAR DNA; COMPLEMENTARY DNA; SHORT HAIRPIN RNA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CRE GENE; GENE; GENE EXPRESSION; GENE TARGETING; GENOME; HUMAN; HUMAN CELL; NEOPLASM; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; TISSUE SPECIFICITY;

ADENOVIRIDAE; ALPHA-FETOPROTEINS; CELL LINE; CELL LINE, TUMOR; ESCHERICHIA COLI; GENETIC VECTORS; HUMANS; INTEGRASES; MUTATION; PROMOTER REGIONS, GENETIC; RNA, SMALL INTERFERING;

ADENOVIRIDAE;

EID: 79551504725     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkq966     Document Type: Article

References (43)

1. Niwa, H., Yamamura, K. and Miyazaki, J. (1991) Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene, 108, 193-199.
2. Kim, D.W., Uetsuki, T., Kaziro, Y., Yamaguchi, N. and Sugano, S. (1990) Use of the human elongation factor 1 alpha promoter as a versatile and efficient expression system. Gene, 91, 217-223.
3. Sato, Y., Tanaka, K., Lee, G., Kanegae, Y., Sakai, Y., Kaneko, S., Nakabayashi, H., Tamaoki, T. and Saito, I. (1998) Enhanced and specific gene expression via tissue-specific production of Cre recombinase using adenovirus vector. Biochem. Biophys. Res. Commun., 244, 455-462.
4. Wilson, C., Bellen, H.J. and Gehring, W.J. (1990) Position effects on eukaryotic gene expression. Annu. Rev. Cell Biol., 6, 679-714.
5. Giraldo, P. and Montoliu, L. (2001) Size matters: use of YACs, BACs and PACs in transgenic animals. Transgenic Res., 10, 83-103.
6. Kijima, T., Osaki, T., Nishino, K., Kumagai, T., Funakoshi, T., Goto, H., Tachibana, I., Tanio, Y. and Kishimoto, T. (1999) Application of the Cre recombinase/loxP system further enhances antitumor effects in cell type-specific gene therapy against carcinoembryonic antigen-producing cancer. Cancer Res., 59, 4906-4911.
7. Ueda, K., Iwahashi, M., Nakamori, M., Nakamura, M., Yamaue, H. and Tanimura, H. (2000) Enhanced selective gene expression by adenovirus vector using Cre/loxP regulation system for human carcinoembryonic antigen-producing carcinoma. Oncology, 59, 255-265.
8. Ueda, K., Iwahashi, M., Nakamori, M., Nakamura, M., Matsuura, I., Yamaue, H. and Tanimura, H. (2001) Carcinoembryonic antigen-specific suicide gene therapy of cytosine deaminase/ 5-fluorocytosine enhanced by the cre/loxP system in the orthotopic gastric carcinoma model. Cancer Res., 61, 6158-6162.
9. Goto, H., Osaki, T., Kijima, T., Nishino, K., Kumagai, T., Funakoshi, T., Kimura, H., Takeda, Y., Yoneda, T., Tachibana, I. et al. (2001) Gene therapy utilizing the Cre/loxP system selectively suppresses tumor growth of disseminated carcinoembryonic antigen-producing cancer cells. Int. J. Cancer, 94, 414-419.
10. Ueda, K., Iwahashi, M., Nakamori, M., Nakamura, M., Matsuura, I., Ojima, T. and Yamaue, H. (2003) Improvement of carcinoembryonic antigen-specific prodrug gene therapy for experimental colon cancer. Surgery, 133, 309-317.
11. Nagayama, Y., Nishihara, E., Iitaka, M., Namba, H., Yamashita, S. and Niwa, M. (1999) Enhanced efficacy of transcriptionally targeted suicide gene/prodrug therapy for thyroid carcinoma with the Cre-loxP system. Cancer Res., 59, 3049-3052.
12. Sakai, Y., Kaneko, S., Sato, Y., Kanegae, Y., Tamaoki, T., Saito, I. and Kobayashi, K. (2001) Gene therapy for hepatocellular carcinoma using two recombinant adenovirus vectors with alpha-fetoprotein promoter and Cre/lox P system. J. Virol. Methods, 92, 5-17.
13. Yoshimura, I., Ikegami, S., Suzuki, S., Tadakuma, T. and Hayakawa, M. (2002) Adenovirus mediated prostate specific enzyme prodrug gene therapy using prostate specific antigen promoter enhanced by the Cre-loxP system. J. Urol., 168, 2659-2664.
14. Maeda, M., Namikawa, K., Kobayashi, I., Ohba, N., Takahara, Y., Kadono, C., Tanaka, A. and Kiyama, H. (2006) Targeted gene therapy toward astrocytoma using a Cre/loxP-based adenovirus system. Brain Res., 1081, 34-43.
15. Namikawa, K., Murakami, K., Okamoto, T., Okado, H. and Kiyama, H. (2006) Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome. Gene Ther., 13, 1244-1250.
16. Graham, F.L., Smiley, J., Russell, W.C. and Nairn, R. (1977) Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J. Gen. Virol., 36, 59-74.
17. Aden, D.P., Fogel, A., Plotkin, S., Damjanov, I. and Knowles, B.B. (1979) Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line. Nature, 282, 615-616.
18. Nakabayashi, H., Taketa, K., Miyano, K., Yamane, T. and Sato, J. (1982) Growth of human hepatoma cells lines with differentiated functions in chemically defined medium. Cancer Res., 42, 3858-3863.
19. Fogh, J., Fogh, J.M. and Orfeo, T. (1977) One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice. J. Natl Cancer Inst., 59, 221-226.
20. Ido, A., Nakata, K., Kato, Y., Nakao, K., Murata, K., Fujita, M., Ishii, N., Tamaoki, T., Shiku, H. and Nagataki, S. (1995) Gene therapy for hepatoma cells using a retrovirus vector carrying herpes simplex virus thymidine kinase gene under the control of human alpha-fetoprotein gene promoter. Cancer Res., 55, 3105-3109.
21. Fukuda, H., Terashima, M., Koshikawa, M., Kanegae, Y. and Saito, I. (2006) Possible mechanism of adenovirus generation from a cloned viral genome tagged with nucleotides at its ends. Microbiol. Immunol., 50, 643-654.
22. Kanegae, Y., Makimura, M. and Saito, I. (1994) A simple and efficient method for purification of infectious recombinant adenovirus. Jpn. J. Med. Sci. Biol., 47, 157-166.
23. Sambrook, J. and Russell. (1989) Molecular Cloning: A Laboratory Manual, Vol. 1, 3rd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
24. Kanegae, Y., Takamori, K., Sato, Y., Lee, G., Nakai, M. and Saito, I. (1996) Efficient gene activation system on mammalian cell chromosomes using recombinant adenovirus producing Cre recombinase. Gene, 181, 207-212.
25. Saito, I., Oya, Y., Yamamoto, K., Yuasa, T. and Shimojo, H. (1985) Construction of nondefective adenovirus type 5 bearing a 2.8-kilobase hepatitis B virus DNA near the right end of its genome. J. Virol., 54, 711-719.
26. Kondo, S., Takata, Y., Nakano, M., Saito, I. and Kanegae, Y. (2009) Activities of various FLP recombinases expressed by adenovirus in mammalian cells. J. Molec. Biol., 390, 221-230.
27. Miyake, S., Makimura, M., Kanegae, Y., Harada, S., Sato, Y., Takamori, K., Tokuda, C. and Saito, I. (1996) Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome. Proc. Natl Acad. Sci. USA, 93, 1320-1324.
28. Bett, A.J., Prevec, L. and Graham, F.L. (1993) Packaging capacity and stability of human adenovirus type 5 vectors. J. Virol., 67, 5911-5921.
29. Nakai, M., Komiya, K., Murata, M., Kimura, T., Kanaoka, M., Kanegae, Y. and Saito, I. (2007) Expression of pIX gene induced by transgene promoter: possible cause of host immune response in first-generation adenoviral vectors. Hum. Gene Ther., 18, 925-936.
30. Leblois, H., Roche, C., Di Falco, N., Orsini, C., Yeh, P. and Perricaudet, M. (2000) Stable transduction of actively dividing cells via a novel adenoviral/episomal vector. Mol. Ther., 1, 314-322.
31. Yant, S.R., Ehrhardt, A., Mikkelsen, J.G., Meuse, L., Pham, T. and Kay, M.A. (2002) Transposition from a gutless adeno-transposon vector stabilizes transgene expression in vivo. Nat. Biotechnol., 20, 999-1005.
32. Gil, J.S., Gallaher, S.D. and Berk, A.J. (2010) Delivery of an EBV episome by a self-circularizing helper-dependent adenovirus: long-term transgene expression in immunocompetent mice. Gene Ther., doi:10.1038/gt.2010.75.
33. Dorigo, O., Gil, J.S., Gallaher, S.D., Tan, B.T., Castro, M.G., Lowenstein, P.R., Calos, M.P. and Berk, A.J. (2004) Development of a novel helper-dependent adenovirus-Epstein-Barr virus hybrid system for the stable transformation of mammalian cells. J. Virol., 78, 6556-6566.
34. Lee, J.H., Yi, S.M., Anderson, M.E., Berger, K.L., Welsh, M.J., Klingelhutz, A.J. and Ozbun, M.A. (2004) Propagation of infectious human papillomavirus type 16 by using an adenovirus and Cre/LoxP mechanism. Proc. Natl Acad. Sci. USA, 101, 2094-2099.
35. Nakano, M., Odaka, K., Takahashi, Y., Ishimura, M., Saito, I. and Kanegae, Y. (2005) Production of viral vectors using recombinase-mediated cassette exchange. Nucleic Acids Res., 33, e76.
36. Bett, A.J., Haddara, W., Prevec, L. and Graham, F.L. (1994) An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3. Proc. Natl Acad. Sci. USA, 91, 8802-8806.
37. Mizuguchi, H. and Kay, M.A. (1998) Efficient construction of a recombinant adenovirus vector by an improved in vitro ligation method. Hum. Gene Ther., 9, 2577-2583.
38. Mizuguchi, H. and Kay, M.A. (1999) A simple method for constructing E1- and E1/E4-deleted recombinant adenoviral vectors. Hum. Gene Ther., 10, 2013-2017.
39. Huyn, S.T., Burton, J.B., Sato, M., Carey, M., Gambhir, S.S. and Wu, L. (2009) A potent, imaging adenoviral vector driven by the cancer-selective mucin-1 promoter that targets breast cancer metastasis. Clin. Cancer Res., 15, 3126-3134.
40. Toth, K., Dhar, D. and Wold, W.S. (2010) Oncolytic (replication- competent) adenoviruses as anticancer agents. Expert Opin. Biol. Ther., 10, 353-368.
41. Mathis, J.M., Stoff-Khalili, M.A. and Curiel, D.T. (2005) Oncolytic adenoviruses - selective retargeting to tumor cells. Oncogene, 24, 7775-7791.
42. Steinwaerder, D.S., Carlson, C.A. and Lieber, A. (2001) Human papilloma virus E6 and E7 proteins support DNA replication of adenoviruses deleted for the E1A and E1B genes. Mol. Ther., 4, 211-216.
43. Ghosh, S. and Duigou, G.J. (2005) Decreased replication ability of D1-deleted adenoviruses correlates with increased brain tumor malignancy. Cancer Res., 65, 8936-8943.