Interleukin-15 affects serotonin system and exerts antidepressive effects through IL15Rα receptor

Psychoneuroendocrinology

Volumn 36, Issue 2, 2011, Pages 266-278

  Wu, Xiaojun ^a   Hsuchou, Hung ^a   Kastin, Abba J ^a   He, Yi ^a   Khan, Reas S ^a   Stone, Kirsten P ^a   Cash, Michael S ^a   Pan, Weihong ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

Author keywords

5 HT; Brain; Depression; IL15; IL15R ; Neurotransmitter; SERT

Indexed keywords

FLUOXETINE; INTERLEUKIN 15; INTERLEUKIN 15 RECEPTOR ALPHA; MESSENGER RNA; SEROTONIN 1A RECEPTOR; SEROTONIN 2C RECEPTOR; SEROTONIN TRANSPORTER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDEPRESSIVE ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE RESPONSE; DEPRESSION; DRUG ACTIVITY; EX VIVO STUDY; FEMALE; FORCED SWIMMING TEST; HIPPOCAMPUS; IMMOBILIZATION; IMMUNOREACTIVITY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; ROTAROD TEST; SEROTONINERGIC SYSTEM; SEROTONINERGIC TRANSMISSION; TREATMENT RESPONSE;

ANIMALS; ANTIDEPRESSIVE AGENTS; CELLS, CULTURED; DEPRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; FLUOXETINE; FREEZING REACTION, CATALEPTIC; INTERLEUKIN-15; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVOUS SYSTEM; RECEPTORS, INTERLEUKIN-15; SEROTONIN; SYNAPTIC TRANSMISSION; SYNAPTOSOMES; TIME FACTORS;

EID: 79551496849     PISSN: 03064530     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2010.07.017     Document Type: Article

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