Interaction of transcriptional repressor ArgR with transcriptional regulator FarR at the argB promoter region in corynebacterium glutamicum

Applied and Environmental Microbiology

Volumn 77, Issue 3, 2011, Pages 711-718

  Lee, Soo Youn ^a,b   Park, Jae Min ^c   Lee, Jin Hyung ^b   Chang, Suk Tai ^d   Park, Jin Soo ^e   Kim, Yang Hoon ^c   Min, Jiho ^a  

^a Chonbuk National University   (South Korea)

^b Korea Institute of Ceramic Engineering and Technology (KICET)   (South Korea)

^c Chungbuk National University   (South Korea)

^d Chung Ang University   (South Korea)

^e Sangmyung University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING DOMAIN; CORYNEBACTERIUM GLUTAMICUM; DNA BINDING; ELECTROPHORETIC MOBILITY SHIFT ASSAY; EXPRESSION LEVELS; IN-SILICO; IN-VITRO; MRNA LEVEL; MUTATIONAL ANALYSIS; PROMOTER REGION; PROTEIN BINDING; TRANSCRIPTIONAL REGULATOR; TRANSCRIPTIONAL REPRESSORS;

AMINO ACIDS; BIOCHEMISTRY; ELECTROPHORETIC MOBILITY; GENE EXPRESSION; NUCLEIC ACIDS; PROTEINS;

BINDING SITES;

ARGININE; ARGR PROTEIN, BACTERIA; BACTERIAL DNA; BACTERIAL PROTEIN; DNA BINDING PROTEIN; PROLINE; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR;

BACTERIUM; BIOASSAY; GENE; PROTEIN;

ARTICLE; BINDING SITE; CHEMISTRY; CORYNEBACTERIUM GLUTAMICUM; DNA SEQUENCE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN BINDING;

ARGININE; BACTERIAL PROTEINS; BASE SEQUENCE; BINDING SITES; CORYNEBACTERIUM GLUTAMICUM; DNA, BACTERIAL; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; MOLECULAR SEQUENCE DATA; PROLINE; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; REPRESSOR PROTEINS; SEQUENCE ANALYSIS, DNA; TRANSCRIPTION FACTORS;

CORYNEBACTERIUM GLUTAMICUM;

EID: 79551473999     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.01610-10     Document Type: Article

References (36)

1. Brinkrolf, K., I. Brune, and A. Tauch. 2007. The transcriptional regulatory network of the amino acid producer Corynebacterium glutamicum. J. Bio-technol. 129:191-211.
2. Brune, I., K. Brinkrolf, J. Kalinowski, A. Pühler, and A. Tauch. 2005. The individual and common repertoire of DNA-binding transcriptional regulators of Corynebacterium glutamicum, Corynebacterium efficiens, Corynebacte-rium diphtheriae and Corynebacterium jeikeium deduced from the complete genome sequence. BMC Genomics 6:86.
3. Caldara, M., P. N. Minh, S. Bostoen, J. Massant, and D. Charlier. 2007. ArgR-dependent repression of arginine and histidine transport genes in Escherichia coli K-12. J. Mol. Biol. 373:251-267.
4. Crooks, G. E., G. Hon, J. M. Chandonia, and S. E. Brenner. 2004. WebLogo: a sequence logo generator. Genome Res. 14:1188-1190.
5. Eggeling, L., and M. Bott. 2005. Handbook of Corynebacterium glutamicum. CRC Press, Taylor & Francis Group, Boca Raton, FL.
6. Ghochikyan, A., et al. 2002. Arginine operator binding by heterologous and chimeric ArgR repressors from Escherichia coli and Bacillus stearothermophi-lus. J. Bacteriol. 184:6602-6614.
7. Grandori, R., et al. 1995. The DNA-binding domain of the hexameric argi-nine repressor. J. Mol. Biol. 254:150-162.
8. Hänßler, E., et al. 2007. FarR, a putative regulator of amino acid metabolism in Corynebacterium glutamicum. Appl. Environ. Microbiol. 76:625-632.
9. Hänßler, E., et al. 2009. A game with many players: control of gdh transcription in Corynebacterium glutamicum. J. Biotechnol. 142:114-122.
10. Hwang, J. H., G. H. Hwang, and J. Y. Cho. 2008. Effect of increased gluta-mate availability on L-ornithine production in Corynebacterium glutamicum. J. Microbiol. Biotechnol. 18:704-710.
11. Ikeda, M., and S. Nakagawa. 2003. The Corynebacterium glutamicum genome: features and impacts on biotechnological processes. Appl. Microbiol. Biotechnol. 62:99-109.
12. Kimura, E., C. Abe, Y. Kawahara, T. Nakamatsu, and H. Tokuda. 1997. A dtsR gene-disrupted mutant of Brevibacterium lactofermentum requires fatty acids for growth and efficiently produces L-glutamate in the presence of an excess of biotin. Biochem. Biophys. Res. Commun. 234:157-161.
13. Lee, S. Y., et al. 2010. Utilization of phenol and naphthalene affects synthesis of differential amino acids in Corynebacterium glutamicum. Curr. Microbiol. 61:596-600.
14. Lee, S. Y., H. S. Shin, J.-S. Park, Y. H. Kim, and J. Min. 2010. Proline reduces the binding of transcriptional regulator ArgR to upstream of argB in Corynebacterium glutamicum. Appl. Microbiol. Biotechnol. 86:235-242.
15. Lee, S. Y., Y. H. Kim, and J. Min. 2010. Conversion of phenol to glutamate and proline in Corynebacterium glutamicum is regulated by transcriptional regulator ArgR. Appl. Microbiol. Biotechnol. 85:713-720.
16. Lee, S. Y., Y. H. Kim, and J. Min. 2009. The effect of ArgR-DNA binding affinity on ornithine production in Corynebacterium glutamicum. Curr. Mi-crobiol. 59:483-488.
17. Lee, Y. J., and J. Y. Cho. 2006. Genetic manipulation of a primary metabolic pathway for L-ornithine production in Escherichia coli. Biotechnol. Lett. 28:1849-1856.
18. Leuchtenberger, W., K. Huthmacher, and K. Drauz. 2005. Biotechnological production of amino acids and derivatives: current status and prospects. Appl. Microbiol. Biotechnol. 69:1-8.
19. Maas, W. K. 1994. The arginine repressor of Escherichia coli. Microbiol. Rev. 58:631-640.
20. Makarova, K. S., A. A. Mironov, and M. S. Gelfand. 2001. Conservation of the binding site for the arginine repressor in all bacterial lineages. Genome Biol. 2:1-8.
21. Marco-Marín, C., et al. 2007. A novel two-domain architecture within the amino acid kinase enzyme family revealed by the crystal structure of Esch-erichia coli glutamate 5-kinase. J. Mol. Biol. 367:1431-1446.
22. Park, S. M., C. D. Lu, and A. T. Abdelal. 1997. Cloning and characterization of argR, a gene that participates in regulation of arginine biosynthesis and catabolism in Pseudomonas aeruginosa PAO1. J. Bacteriol. 179:5300-5308.
23. Pátek, M., J. Něsvera, A. Guyonvarch, O. Reyes, and G. Leblon. 2003. Promoters of Corynebacterium glutamicum. J. Biotechnol. 10:311-323.
24. Paul, L., P. K. Mishra, R. M. Blumenthal, and R. G. Matthews. 2007. Integration of regulatory signals through involvement of multiple global regulators: control of the Escherichia coli gltBDF operon by Lrp, IHF, Crp, and ArgR. BMC Microbiol. 7:1-17.
25. Ṕerez-Arellano, I., V. Rubio, and J. Cervera. 2006. Mapping active site residue in glutamate-5-kinase. The substrate glutamate and the feed-back inhibitor proline bind at overlapping sites. FEBS Lett. 580:6247-6253.
26. Quail, M. A., C. E. Dempsey, and J. R. Guest. 1994. Identification of a fatty acyl responsive regulator (FarR) in Escherichia coli. FEMS Lett. 356:183- 187.
27. Rigali, S., A. Derouaux, F. Giannotta, and J. Dusart. 2002. Subdivision of the helix-turn-helix GntR family of bacterial regulators in the FadR, HutC, MocR, and YtrA subfamilies. J. Biol. Chem. 277:12507-12515.
28. Sakanyan, V., et al. 1996. Genes and enzymes of the acetyl cycle of arginine biosynthesis in Corynebacterium glutamicum: enzyme evolution in the early steps of the arginine pathway. Microbiology 142:99-108.
29. Sambrook, J., and D. W. Russell. 2001. Molecular cloning: a laboratory manual, 3rd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
30. Sampaio, M., et al. 2004. Phosphotransferase-mediated transport of the osmoolyte 2-O-a-mannosyl-D-glycerate in Escherichia coli occurs by the product of the mngA (hrsA) gene and is regulated by the mngR (farR) gene product acting as repressor. J. Biol. Chem. 279:5537-5548.
31. Thompson, J. D., T. J. Gibson, F. Plewniak, F. Jeanmougin, and D. G. Higgins. 1997. The Clustal X Windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 25:4876-4882.
32. Udaka, S. 1960. Screening method for microorganisms accumulating metabolites and its use in the isolation of Micrococcus glutamicus. J. Bacteriol. 79:754-755.
33. van Duyne, G. D., G. Ghosh, W. K. Maas, and P. B. Sigler. 1994. Structure of the oligomerization and L-arginine binding domain of the arginine repressor of Escherichia coli. J. Mol. Biol. 256:377-391.
34. Xu, Y., B. Labedan, and N. Glansdorff. 2007. Surprising arginine biosynthesis: a reappraisal of the enzymology and evolution of the pathway in microorganisms. Microbiol. Mol. Biol. Rev. 71:36-47.
35. Xu, Y., et al. 2003. Regulation of arginine biosynthesis in the psychropiezo-philic bacterium Moritella profunda: in vivo repressibility and in vitro repres-sor-operator contact probing. J. Mol. Biol. 326:353-369.
36. Yao, W., et al. 2009. Double deletion of dtsR1 and pyc induce efficient L-glutamate overproduction in Corynebacterium glutamcium. J. Ind. Microbiol. Biotechnol. 36:911-921.