A Novel Two-domain Architecture Within the Amino Acid Kinase Enzyme Family Revealed by the Crystal Structure of Escherichia coli Glutamate 5-kinase

Journal of Molecular Biology

Volumn 367, Issue 5, 2007, Pages 1431-1446

  Marco Marín, Clara ^a   Gil Ortiz, Fernando ^a   Pérez Arellano, Isabel ^b   Cervera, Javier ^b   Fita, Ignacio ^c   Rubio, Vicente ^a  

^a INSTITUTO DE SALUD CARLOS III   (Spain)

^b CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

^c INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

Author keywords

amino acid kinase family; ornithine synthesis; proline synthesis; PUA domain; 1 pyrroline 5 carboxylate synthetase

Indexed keywords

BACTERIAL ENZYME; DIMER; ESCHERICHIA COLI PROTEIN; GLUTAMIC ACID; MAGNESIUM ION; OXIDOREDUCTASE; PROLINE; PROTEIN G5K; PROTEIN KINASE; PYROGLUTAMIC ACID; SULFATE; TETRAMER; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; BETA SHEET; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME CONFORMATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBUNIT; ESCHERICHIA COLI; HYDROGEN BOND; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 33947190385     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2007.01.073     Document Type: Article

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