The role of nitric oxide in the pathophysiology of thromboembolic stroke in the rat

Brain Research

Volumn 759, Issue 1, 1997, Pages 32-40

  Stagliano, N E ^a   Dietrich, W D ^a   Prado, R ^a   Green, E J ^a   Busto, R ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Behavior; Ischemia; Nitric oxide; Nitric oxide synthase inhibition; Rat; Stroke

Indexed keywords

NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN CORTEX; BRAIN INJURY; BRAIN ISCHEMIA; CAROTID ARTERY THROMBOSIS; COMMON CAROTID ARTERY; CONTROLLED STUDY; ENZYME ACTIVITY; HIPPOCAMPUS; MALE; MAZE TEST; NERVE CELL LESION; NONHUMAN; PRIORITY JOURNAL; RAT; STROKE; THROMBOEMBOLISM;

ANIMALS; ARGININE; BEHAVIOR, ANIMAL; BLOOD PRESSURE; CEREBROVASCULAR DISORDERS; CITRULLINE; COGNITION DISORDERS; ENZYME INHIBITORS; INTRACRANIAL EMBOLISM AND THROMBOSIS; MALE; MOTOR CORTEX; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; RATS; RATS, WISTAR; SOMATOSENSORY CORTEX; THROMBOEMBOLISM;

EID: 0030805143     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)00200-X     Document Type: Article

References (37)

1. Alexis N.E., Dietrich W.D., Green E.J., Prado R., Watson B.D. Non-occlusive common carotid artery thrombosis (CCAT) in the rat results in reversible sensorimotor and cognitive behavioral deficits. Stroke. 26:1995;2338-2346.
2. Attella M.J., Hoffman S.W., Pilotte M.P., Stein D.G. Effects of BIM-22015, an analog of ACTH4-10, on functional recovery after frontal cortex injury. Behav. Neurol. Biol. 57:1992;157-166.
3. Bannerman D.M., Chapman P.F., Kelly P.A.T., Butcher S.P., Morris R.G.M. Inhibition of nitric oxide synthase does not impair spatial learning. J. Neurosci. 14:1994;7404-7414.
4. Bederson J.B., Pitts L.H., Tsuji M., Nishimura M.C., Davis R.L., Bartkowski H. Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke. 17:1986;472-486.
5. Clifton G.L., Jiang J.Y., Lyeth B.G., Jenkins L.W., Hamm R.J., Hayes R.L. Marked protection by moderate hypothermia after experimental traumatic brain injury. J. Cereb. Blood Flow. Metab. 11:1991;114-121.
6. Coyle P. Spatial relations of dorsal anastomoses and lesion boundary after middle cerebral artery occlusion. Stroke. 18:1987;1133-1140.
7. DeRyck M., Van Reempts J., Duytschaever H., Van Deuren B., Clincke G. Neocortical localization of tactile and proprioceptive limb placing reactions in the rat. Brain Res. 573:1992;44-60.
8. Dietrich W.D., Prado R., Watson B.D., Busto R., Ginsberg M.D. Hemodynamic consequences of common carotid artery thrombosis and thrombogenically activated blood in rats. J. Cereb. Blood Flow. Metab. 11:1991;957-965.
9. Dietrich W.D., Prado R., Halley M., Watson B.D. Microvascular and neuronal consequences of common carotid artery thrombosis and platelet embolization in rats. J. Neuropath. Exp. Neuro. 52:1993;351-360.
10. 111In-labeled platelet study. Stroke. 24:1993;1534-1540.
11. W.D. Dietrich, R. Prado, B.D. Watson, Pathway dependent therapeutic windows for mitigating the pathophysiology of thromboembolic stroke. In J. Krieglstein, H. Oberpichler-Schwenk (Eds.), Pharmacology of Cerebral Ischemia 1994, Scientific Publishers, Stuttgart, 1994, pp. 565-574.
12. Faraci F.M., Brian J.E. Nitric oxide and the cerebral circulation. Stroke. 25:1994;692-703.
13. Futrell N., Watson B.D., Dietrich W.D., Prado R., Millikan C., Ginsberg M.D. A new model of embolic stroke produced by photochemical injury to the carotid artery in the rat. Ann. Neurol. 23:1988;251-257.
14. Garofolo L., Elliott P.J., Cuello A.C. Behavioral response of rats with cortical lesions to cholinomimetics. Physiol. Behav. 52:1992;971-977.
15. Heiss W.D. Progress in cerebrovascular disease: flow thresholds of functional and morphological damage of brain tissue. Stroke. 14:1983;329-331.
16. Huang Z., Huang P.L., Panahian N., Dalkara T., Fishman M.C., Moskowitz M.A. Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase. Science. 265:1994;1883-1885.
17. Huang Z., Huang P.L., Ma J., Meng W., Ayata C., Fishman M.C., Moskowitz M.A. Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine. J. Cereb. Blood Flow Metab. 16:1996;981-987.
18. Iadecola C., Xu X., Zhang F., Hu J., El-Fakahany E.E. Prolonged inhibition of brain nitric oxide synthase by short-term systemic administration of nitro-L-arginine-methyl-ester. Neurochem. Res. 19:1994;501-505.
19. Iadecola C., Zhang F., Xu X. Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage. Am. J. of Physiol. 268:1995;R286-R292.
20. Jaspers R.M., Block F., Heim C., Sontag K.H. Spatial learning is affected by transient occlusion of common carotid arteries (2VO): comparison of behavioral and histopathological changes after '2VO' and 'four vessel occlusion' in rats. Neurosci. Lett. 117:1990;149-153.
21. Kuluz J.W., Prado R., Dietrich W.D., Schleien C.L., Watson B.D. The effect of nitric oxide synthase inhibition on infarct volume after reversible focal cerebral ischemia in conscious rats. Stroke. 24:1993;2023-2029.
22. Malinski T., Kapturczak M., Dayharsh J., Bohr D. Nitric oxide synthase activity in genetic hypertension. Biochem. Biophys. Res. Commun. 194:1993;654-658.
23. Morikawa E., Huang Z., Moskowitz M.A. L-Arginine decreases infarct size caused by middle cerebral artery occlusion in spontaneously hypertensive rats. Am. J. Physiol. 263:1992;H1632-H1635.
24. Morikawa E., Rosenblatt S., Moskowitz M.A. L-Arginine dilates rat pial arterioles by nitric oxide-dependent mechanisms and increases blood flow during focal cerebral ischemia. Br. J. Pharmacol. 107:1992;905-907.
25. Nowicki J.P., Duval D., Poignet H., Scatton B. Nitric oxide mediates neuronal death after focal cerebral ischemia in the mouse. Eur. J. Pharmacol. 204:1991;339-340.
26. Nishikana T., Kirsch J.R., Koehler R.C., Bredt D.S., Snyder S.H., Traysman R.J. N-Nitro-L-arginine methyl ester attenuates caudate injury during focal ischemia in cats. J. Cereb. Blood Flow Metab. 13:1994;S154.
27. Prado R., Watson B.D., Zhao W., Yao H., Busto R., Dietrich W.D., Ginsberg M.D. L-Arginine does not improve cortical perfusion or histopathological outcome in spontaneously hypertensive rats subjected to distal middle cerebral artery photothrombotic occlusion. J. Cereb. Blood Flow Metab. 16:1996;612-622.
28. Prado R., Watson B.D., Wester P. Effects of nitric oxide synthase inhibition on cerebral blood flow following bilateral carotid artery occlusion and recirculation in the rat. J. Cereb. Blood Flow Metab. 13:1993;720-723.
29. Radomski M.W., Palmer R.M.J., Moncada S. An L-arginine/nitric oxide pathway present in human platelets regulates aggregation. Proc. Natl. Acad. Sci. USA. 87:1990;5193-5197.
30. Watson B.D., Dietrich W.D., Prado R., Ginsberg M.D. Argon laser-induced arterial photothrombosis. J. Neurosurg. 66:1987;748-754.
31. Wester P., Dietrich W.D., Prado R., Watson B.D., Globus M.Y.-T. Serotonin release into plasma during common carotid artery thrombosis. Stroke. 23:1992;870-875.
32. Yamamato S., Golanov E.V., Berger S.B., Reis D.J. Inhibition of nitric oxide synthesis increases focal ischemic infarction in rat. J. Cereb. Blood Flow Metab. 12:1992;717-726.
33. Yonemori F., Yamada H., Yamaguchi T., Uemura A., Tamura A. Spatial memory disturbance after focal cerebral ischemia in rats. J. Cereb. Blood Flow Metab. 16:1996;973-980.
34. Zhang F., White J.G., Iadecola C. Nitric oxide donors increase blood flow and reduce brain damage in focal ischemia: evidence that nitric oxide is beneficial in the early stages on cerebral ischemia. J. Cereb. Blood Flow Metab. 14:1994;217-226.
35. Zhang F., Xu S., Iadecola C. Time dependence of effect of nitric oxide synthase inhibition on cerebral ischemic damage. J. Cereb. Blood Flow Metab. 15:1995;595-601.
36. Zhang F., Casey R.M., Ross M.E., Iadecola C. Aminoguanidine ameliorates and L-arginine worsens brain damage from intraluminal middle cerebral artery occlusion. Stroke. 27:1996;317-323.
37. K. Zilles, The Cortex of the Rat, Springer-Verlag, New York, 1985.