Solid-phase extraction and ultra high-performance liquid chromatography tandem mass spectrometry analysis of the gastrointestinal absorption of emodin in different digestive segments of rats

Journal of Separation Science

Volumn 34, Issue 3, 2011, Pages 260-267

  Kong, Weijun ^a,b   Xia, Xinhua ^c   Wang, Jiabo ^a   Zhou, Canping ^a,c   Fang, Fang ^a,b   Xing, Xiaoyan ^a,b   Jin, Cheng ^a   Zhao, Yanling ^a   Zang, Qingce ^a,d   Xiao, Xiaohe ^a  

^a BEIJING 302 HOSPITAL   (China)

^b CHENGDU UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c HUNAN UNIVERSITY OF CHINESE MEDICINE   (China)

^d JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Digestive segment; Emodin; Gastrointestinal absorption; SPE; UHPLC ESI MS MS

Indexed keywords

DIGESTIVE SEGMENT; EMODIN; ESI-MS/MS; GASTROINTESTINAL ABSORPTION; SPE;

ABSORPTION; ELECTROSPRAY IONIZATION; EXTRACTION; FORMIC ACID; LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETRY; METHANOL;

ABSORPTION SPECTROSCOPY;

DANTRON; EMODIN; FORMIC ACID; METHANOL;

ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTICLE; BLOOD SAMPLING; COLON; CONTROLLED STUDY; DRUG ABSORPTION; DRUG RETENTION; DUODENUM; ELECTROSPRAY; ELUTION; GASTROINTESTINAL ABSORPTION; ILEUM; IN VIVO STUDY; JEJUNUM; MALE; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; RAT; SOLID PHASE EXTRACTION; STOMACH; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EMODIN; GASTROINTESTINAL TRACT; INTESTINAL ABSORPTION; MALE; RATS; RATS, SPRAGUE-DAWLEY; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

RATTUS;

EID: 79251592274     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.201000757     Document Type: Article

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