The C-terminus of H-ras as a target for the covalent binding of reactive compounds modulating Ras-dependent pathways

PLoS ONE

Volumn 6, Issue 1, 2011, Pages

  Oeste, Clara L ^a   Díez Dacal, Beatriz ^a   Bray, Francesca ^a   de Lacoba, Mario García ^a   de la Torre, Beatriz G ^b   Andreu, David ^b   Ruiz Sánchez, Antonio J ^c   Pérez Inestrosa, Ezequiel ^c   García Domínguez, Carlota A ^d   Rojas, José M ^d   Pérez Sala, Dolores ^a  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^b UNIVERSITAT POMPEU FABRA   (Spain)

^c UNIVERSITY OF MÁLAGA   (Spain)

^d INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; ARSENOSOBENZENE; BROMOBIMANE; CYCLOPENTENONE PROSTAGLANDIN; CYSTEINE; DELTA12 PROSTAGLANDIN J2; H RAS PROTEIN; PROSTAGLANDIN DERIVATIVE; RAS PROTEIN; UNCLASSIFIED DRUG; BICYCLO COMPOUND; CROSS LINKING REAGENT; CYCLOPENTANE DERIVATIVE; CYCLOPENTENONE; DIBROMOBIMANE; ENZYME INHIBITOR; ORGANOARSENIC DERIVATIVE; PROSTAGLANDIN; PROTEIN P21;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CELL STRAIN COS7; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; COVALENT BOND; IN VITRO STUDY; INHIBITION KINETICS; NONHUMAN; PROTEIN CROSS LINKING; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN MODIFICATION; PROTEIN TARGETING; ANIMAL; BINDING SITE; CELL LINE; CHEMISTRY; DRUG EFFECT; GENETIC TRANSFECTION; HUMAN; METABOLISM; PROTEIN BINDING; PROTEIN PROCESSING; SIGNAL TRANSDUCTION;

ANIMALS; ARSENICALS; BICYCLO COMPOUNDS; BINDING SITES; CELL LINE; CROSS-LINKING REAGENTS; CYCLOPENTANES; CYSTEINE; ENZYME INHIBITORS; HUMANS; PROSTAGLANDINS; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS P21(RAS); RAS PROTEINS; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 79251578938     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0015866     Document Type: Article

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