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Volumn 93, Issue 3, 2011, Pages 341-349

Functional recovery after severe CNS trauma: Current perspectives for cell therapy with bone marrow stromal cells

Author keywords

Bone marrow stromal cells; Cell transplantation; Stem cells; Traumatic brain injury; Traumatic spinal cord injury

Indexed keywords

BONE MARROW TRANSPLANTATION; CELL THERAPY; CENTRAL NERVOUS SYSTEM; PRIORITY JOURNAL; REVIEW; SPINAL CORD INJURY; TRAUMATIC BRAIN INJURY;

EID: 79251578006     PISSN: 03010082     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pneurobio.2010.12.002     Document Type: Review
Times cited : (58)

References (100)
  • 1
    • 5044220530 scopus 로고    scopus 로고
    • Bone marrow transplants provide tissue protection and directional guidance for axons after contusive spinal cord injury in rats
    • Ankeny D.P., Mc Tigue D.M., Jakeman L.B. Bone marrow transplants provide tissue protection and directional guidance for axons after contusive spinal cord injury in rats. Exp. Neurol. 2004, 190:17-31.
    • (2004) Exp. Neurol. , vol.190 , pp. 17-31
    • Ankeny, D.P.1    Mc Tigue, D.M.2    Jakeman, L.B.3
  • 2
    • 31944433392 scopus 로고    scopus 로고
    • Lumbar puncture delivery of bone marrow stromal cells in spinal cord contusion: a novel method for minimally invasive cell transplantation
    • Bakshi A., Barshinger A.L., Swanger S.A., Madhavani V., Shumsky J.S., Neuhuber B., Fischer I. Lumbar puncture delivery of bone marrow stromal cells in spinal cord contusion: a novel method for minimally invasive cell transplantation. J. Neurotrauma 2006, 23:55-65.
    • (2006) J. Neurotrauma , vol.23 , pp. 55-65
    • Bakshi, A.1    Barshinger, A.L.2    Swanger, S.A.3    Madhavani, V.4    Shumsky, J.S.5    Neuhuber, B.6    Fischer, I.7
  • 3
    • 7944234688 scopus 로고    scopus 로고
    • Minimally invasive delivery of stem cells for spinal cord injury: advantages of the lumbar puncture technique
    • Bakshi A., Hunter C., Swanger S., Lepore A., Fischer I. Minimally invasive delivery of stem cells for spinal cord injury: advantages of the lumbar puncture technique. J. Neurosurg. Spine 2004, 1:330-337.
    • (2004) J. Neurosurg. Spine , vol.1 , pp. 330-337
    • Bakshi, A.1    Hunter, C.2    Swanger, S.3    Lepore, A.4    Fischer, I.5
  • 4
    • 33645984825 scopus 로고    scopus 로고
    • Neural progenitor cells engineered to secrete GDNF show enhanced survival, neuronal differentiation and improve cognitive function following traumatic brain injury
    • Bakshi A., Shimizu S., Keck C.A., Cho S., LeBold D.G., Morales D., Arenas E., Snyder E.Y., Watson D.J., Mcintosh T.K. Neural progenitor cells engineered to secrete GDNF show enhanced survival, neuronal differentiation and improve cognitive function following traumatic brain injury. Eur. J. Neurosci. 2006, 23:2119-2134.
    • (2006) Eur. J. Neurosci. , vol.23 , pp. 2119-2134
    • Bakshi, A.1    Shimizu, S.2    Keck, C.A.3    Cho, S.4    LeBold, D.G.5    Morales, D.6    Arenas, E.7    Snyder, E.Y.8    Watson, D.J.9    Mcintosh, T.K.10
  • 5
    • 0000907388 scopus 로고
    • Lack of regeneration in spinal cord of rat
    • Barnard J.W., Carpenter W. Lack of regeneration in spinal cord of rat. J. Neurophysiol. 1950, 13:223-228.
    • (1950) J. Neurophysiol. , vol.13 , pp. 223-228
    • Barnard, J.W.1    Carpenter, W.2
  • 6
    • 0021262291 scopus 로고
    • Ultrastructure of fetal spinal cord and cortex implants into adult rat spinal cord
    • Bernstein J.J., Patel U., Keleman M., Jefferson M., Turtil S. Ultrastructure of fetal spinal cord and cortex implants into adult rat spinal cord. J. Neurosci. Res. 1984, 11:359-372.
    • (1984) J. Neurosci. Res. , vol.11 , pp. 359-372
    • Bernstein, J.J.1    Patel, U.2    Keleman, M.3    Jefferson, M.4    Turtil, S.5
  • 7
    • 69349089354 scopus 로고    scopus 로고
    • Delayed intralesional transplantation of bone marrow stromal cells increases endogenous neurogenesis and promotes functional recovery after severe traumatic brain injury
    • Bonilla C., Zurita M., Otero L., Aguayo C., Vaquero J. Delayed intralesional transplantation of bone marrow stromal cells increases endogenous neurogenesis and promotes functional recovery after severe traumatic brain injury. Brain Injury 2009, 23:760-769.
    • (2009) Brain Injury , vol.23 , pp. 760-769
    • Bonilla, C.1    Zurita, M.2    Otero, L.3    Aguayo, C.4    Vaquero, J.5
  • 9
    • 0027504205 scopus 로고
    • Recovery of function after spinal cord injury: mechanisms underlying transplant-mediated recovery of funcyion differ after spinal cord injury in newborn and adult rats
    • Bregman B.S., Kunkel-Bagden E., Reier P.J., Dai H.N., Mc Atee M., Gao D. Recovery of function after spinal cord injury: mechanisms underlying transplant-mediated recovery of funcyion differ after spinal cord injury in newborn and adult rats. Exp. Neurol. 1993, 123:3-16.
    • (1993) Exp. Neurol. , vol.123 , pp. 3-16
    • Bregman, B.S.1    Kunkel-Bagden, E.2    Reier, P.J.3    Dai, H.N.4    Mc Atee, M.5    Gao, D.6
  • 10
    • 0001559571 scopus 로고
    • Recovery of function after spinal cord injury: transplantation strategies
    • Raven Press, New York, S.B. Dunnett, A. Bjorkland (Eds.)
    • Bregman B.S. Recovery of function after spinal cord injury: transplantation strategies. Functional Neural Transplantation 1994, 489-529. Raven Press, New York. S.B. Dunnett, A. Bjorkland (Eds.).
    • (1994) Functional Neural Transplantation , pp. 489-529
    • Bregman, B.S.1
  • 11
    • 0000472326 scopus 로고
    • Abortive regeneration of the transected spinal cord
    • Brown J.O., Mc Cough G.P. Abortive regeneration of the transected spinal cord. J. Comp. Neurol. 1947, 87:131-137.
    • (1947) J. Comp. Neurol. , vol.87 , pp. 131-137
    • Brown, J.O.1    Mc Cough, G.P.2
  • 12
    • 0036605563 scopus 로고    scopus 로고
    • Stem cell repair of central nervous system injury
    • Cao Q., Benton R.L., Whittemore S.R. Stem cell repair of central nervous system injury. J. Neurosci. Res. 2002, 68:501-510.
    • (2002) J. Neurosci. Res. , vol.68 , pp. 501-510
    • Cao, Q.1    Benton, R.L.2    Whittemore, S.R.3
  • 13
    • 21244477905 scopus 로고    scopus 로고
    • Protective effects of bone marrow stromal cells transplantation in injured rodent brain: synthesis of neurotrophic factors
    • Chen Q., Long Y., Yuan X., Zou L., Sun J., Chen S., Perez-Polo J.M., Yang K. Protective effects of bone marrow stromal cells transplantation in injured rodent brain: synthesis of neurotrophic factors. J. Neurosci. Res. 2005, 80:611-619.
    • (2005) J. Neurosci. Res. , vol.80 , pp. 611-619
    • Chen, Q.1    Long, Y.2    Yuan, X.3    Zou, L.4    Sun, J.5    Chen, S.6    Perez-Polo, J.M.7    Yang, K.8
  • 15
    • 0013278301 scopus 로고    scopus 로고
    • Treatment of neural injury with marrow stromal cells
    • Chopp M., Li Y. Treatment of neural injury with marrow stromal cells. Lancet Neurol. 2002, 1:92-100.
    • (2002) Lancet Neurol. , vol.1 , pp. 92-100
    • Chopp, M.1    Li, Y.2
  • 16
    • 0034637810 scopus 로고    scopus 로고
    • Spinal cord injury in rat: treatment with bone marrow stromal cell transplantation
    • Chopp M., Zhang X.H., Li Y., Wang L., Chen J., Lu D., Lu M., Rosemblum M. Spinal cord injury in rat: treatment with bone marrow stromal cell transplantation. Neuroreport 2000, 11:3001-3005.
    • (2000) Neuroreport , vol.11 , pp. 3001-3005
    • Chopp, M.1    Zhang, X.H.2    Li, Y.3    Wang, L.4    Chen, J.5    Lu, D.6    Lu, M.7    Rosemblum, M.8
  • 17
    • 0023624168 scopus 로고
    • Neural transplantation in normal and traumatized spinal cord
    • The New York Academy of Sciences, New York
    • Das G.D. Neural transplantation in normal and traumatized spinal cord. Cell and Tissue Transplantation into the Adult Brain 1987, vol. 495:53-70. The New York Academy of Sciences, New York.
    • (1987) Cell and Tissue Transplantation into the Adult Brain , vol.495 , pp. 53-70
    • Das, G.D.1
  • 18
    • 0020974403 scopus 로고
    • Neural transplantation in the spinal cord of adult rats. Conditions, survival, cytology and connectivity of the transplants
    • Das G.D. Neural transplantation in the spinal cord of adult rats. Conditions, survival, cytology and connectivity of the transplants. J. Neurol. Sci. 1983, 62:191-210.
    • (1983) J. Neurol. Sci. , vol.62 , pp. 191-210
    • Das, G.D.1
  • 19
    • 0002958198 scopus 로고
    • Neural transplantation in the spinal cord of the adult mammals
    • Raven Press, New York, C.C. Kao, R.P. Bunge, P.J. Reier (Eds.)
    • Das G.D. Neural transplantation in the spinal cord of the adult mammals. Spinal Cord Reconstruction 1983, 367-396. Raven Press, New York. C.C. Kao, R.P. Bunge, P.J. Reier (Eds.).
    • (1983) Spinal Cord Reconstruction , pp. 367-396
    • Das, G.D.1
  • 20
    • 0019856865 scopus 로고
    • Axonal elongation into peripheral nervous system bridges after central nervous system injury in adult rats
    • David S., Aguayo A.J. Axonal elongation into peripheral nervous system bridges after central nervous system injury in adult rats. Science 1981, 214:931-933.
    • (1981) Science , vol.214 , pp. 931-933
    • David, S.1    Aguayo, A.J.2
  • 21
    • 13844299147 scopus 로고    scopus 로고
    • Detection of 111In-oxine-labeled bone marrow stromal cells after intravenous or intralesional administration in chronic paraplegic rats
    • De Haro J., Zurita M., Ayllón L., Vaquero J. Detection of 111In-oxine-labeled bone marrow stromal cells after intravenous or intralesional administration in chronic paraplegic rats. Neurosci. Lett. 2005, 377:7-11.
    • (2005) Neurosci. Lett. , vol.377 , pp. 7-11
    • De Haro, J.1    Zurita, M.2    Ayllón, L.3    Vaquero, J.4
  • 22
    • 53749099516 scopus 로고    scopus 로고
    • Treatment of chronic spinal cord injured patients with autologous bone marrow-derived hematopoietic stem cell transplantation: 1-year follow-up
    • Deda H., Inci M.C., Kürekçi A.E., Kayihan K., Ozgün E., Ustünsoy G.E., Kocabay S. Treatment of chronic spinal cord injured patients with autologous bone marrow-derived hematopoietic stem cell transplantation: 1-year follow-up. Cytotherapy 2008, 10:565-574.
    • (2008) Cytotherapy , vol.10 , pp. 565-574
    • Deda, H.1    Inci, M.C.2    Kürekçi, A.E.3    Kayihan, K.4    Ozgün, E.5    Ustünsoy, G.E.6    Kocabay, S.7
  • 24
    • 0031962067 scopus 로고    scopus 로고
    • Fetal spinal cord transplants support growth of supraspinal and segmental projections after cervical spinal cord hemisection in the neonatal rat
    • Diener P.S., Bregman B.S. Fetal spinal cord transplants support growth of supraspinal and segmental projections after cervical spinal cord hemisection in the neonatal rat. J. Neurosci. 1998, 18:779-793.
    • (1998) J. Neurosci. , vol.18 , pp. 779-793
    • Diener, P.S.1    Bregman, B.S.2
  • 25
    • 0031214428 scopus 로고    scopus 로고
    • Nerve growth factor attenuates cholinergic deficits following traumatic brain injury in rats
    • Dixon C.E., Flinn P., Bao J., Venya R., Hayes R.L. Nerve growth factor attenuates cholinergic deficits following traumatic brain injury in rats. Exp. Neurol. 1997, 146:479-490.
    • (1997) Exp. Neurol. , vol.146 , pp. 479-490
    • Dixon, C.E.1    Flinn, P.2    Bao, J.3    Venya, R.4    Hayes, R.L.5
  • 28
    • 0022972735 scopus 로고
    • Peripheral nerve autografts to the rat spinal cord: study on the origin and course of regenerating fibres
    • Fernández E., Pallini R., Minciacchi D., Sbriccoli A. Peripheral nerve autografts to the rat spinal cord: study on the origin and course of regenerating fibres. Acta Neurochir. (Wien) 1986, 82:57-63.
    • (1986) Acta Neurochir. (Wien) , vol.82 , pp. 57-63
    • Fernández, E.1    Pallini, R.2    Minciacchi, D.3    Sbriccoli, A.4
  • 29
    • 1642309517 scopus 로고    scopus 로고
    • Bone marrow stromal cells produce nerve growth factor and glial cell line-derived neurotrophic factor
    • García R., Aguiar J., Alberti E., de la Cuetara K., Pavon N. Bone marrow stromal cells produce nerve growth factor and glial cell line-derived neurotrophic factor. Biochem. Biophys. Res. Commun. 2004, 316:753-754.
    • (2004) Biochem. Biophys. Res. Commun. , vol.316 , pp. 753-754
    • García, R.1    Aguiar, J.2    Alberti, E.3    de la Cuetara, K.4    Pavon, N.5
  • 30
    • 62549145360 scopus 로고    scopus 로고
    • Administration of autologous bone marrow stem cells into spinal cord injury patients via multiple routes is safe and improves their quality of life: comprehensive case studies
    • Geffner L.F., Santacruz P., Izurieta M., Flor L., Maldonado B., Auad A.H., Montenegro X., Gonzalez R., Silva F. Administration of autologous bone marrow stem cells into spinal cord injury patients via multiple routes is safe and improves their quality of life: comprehensive case studies. Cell Transplant. 2008, 17:1277-1293.
    • (2008) Cell Transplant. , vol.17 , pp. 1277-1293
    • Geffner, L.F.1    Santacruz, P.2    Izurieta, M.3    Flor, L.4    Maldonado, B.5    Auad, A.H.6    Montenegro, X.7    Gonzalez, R.8    Silva, F.9
  • 34
    • 0025818158 scopus 로고
    • Ethical issues in brain-cell transplantation
    • Hoffer B.J., Olson L. Ethical issues in brain-cell transplantation. Trends Neurosci. 1991, 14:384-388.
    • (1991) Trends Neurosci. , vol.14 , pp. 384-388
    • Hoffer, B.J.1    Olson, L.2
  • 37
    • 1842835635 scopus 로고    scopus 로고
    • In vitro differentiation of size-sieved stem cells into electrically active neural cells
    • Hung S., Cheng H., Pan C., Tsai M.J., Kao L., Ma H. In vitro differentiation of size-sieved stem cells into electrically active neural cells. Stem Cells 2002, 20:522-529.
    • (2002) Stem Cells , vol.20 , pp. 522-529
    • Hung, S.1    Cheng, H.2    Pan, C.3    Tsai, M.J.4    Kao, L.5    Ma, H.6
  • 39
    • 0016268676 scopus 로고
    • Comparison of healing process in transected spinal cords grafted with autogenous brain tissue, sciatic nerve, and no dose ganglion
    • Kao C. Comparison of healing process in transected spinal cords grafted with autogenous brain tissue, sciatic nerve, and no dose ganglion. Exp. Neurol. 1974, 44:424-439.
    • (1974) Exp. Neurol. , vol.44 , pp. 424-439
    • Kao, C.1
  • 40
    • 17444379357 scopus 로고    scopus 로고
    • Immunobiology of humam mesenchymmal stem cells and future use in hematopoietic stem cell transplantation
    • Le Blanc K., Ringden O. Immunobiology of humam mesenchymmal stem cells and future use in hematopoietic stem cell transplantation. Biol. Blood Marrow Transplant. 2005, 11:321-334.
    • (2005) Biol. Blood Marrow Transplant. , vol.11 , pp. 321-334
    • Le Blanc, K.1    Ringden, O.2
  • 41
    • 0141757405 scopus 로고    scopus 로고
    • Migration and differentiation of nuclear fluorescence-labeled bone marrow stromal cells after transplantation into cerebral infarct and spinal cord injury in mice
    • Lee J., Kuroda S., Shichinohe H., Ikeda J., Seki T., Hida K., Tada M., Sawada K., Iwasaki Y. Migration and differentiation of nuclear fluorescence-labeled bone marrow stromal cells after transplantation into cerebral infarct and spinal cord injury in mice. Neuropathology 2003, 23:169-180.
    • (2003) Neuropathology , vol.23 , pp. 169-180
    • Lee, J.1    Kuroda, S.2    Shichinohe, H.3    Ikeda, J.4    Seki, T.5    Hida, K.6    Tada, M.7    Sawada, K.8    Iwasaki, Y.9
  • 43
    • 0035809744 scopus 로고    scopus 로고
    • Adult bone marrow stromal cells administered intravenously to rats after traumatic brain injury migrate into brain and improve neurological outcome
    • Lu D., Mahmood A., Wang L., Li Y., Lu M., Chopp M. Adult bone marrow stromal cells administered intravenously to rats after traumatic brain injury migrate into brain and improve neurological outcome. Neuroreport 2001, 12:559-563.
    • (2001) Neuroreport , vol.12 , pp. 559-563
    • Lu, D.1    Mahmood, A.2    Wang, L.3    Li, Y.4    Lu, M.5    Chopp, M.6
  • 44
    • 33646009967 scopus 로고    scopus 로고
    • Adult bone marrow cells differentiate into neural phenotypes and improve functional recovery in rats following traumatic brain injury
    • Lu J., Moochhala S., Moore X.L., Ng C.K., Tan M.H., Lee L.K.H., He B., Wong M.C., Ling E.A. Adult bone marrow cells differentiate into neural phenotypes and improve functional recovery in rats following traumatic brain injury. Neurosci. Lett. 2006, 398:12-17.
    • (2006) Neurosci. Lett. , vol.398 , pp. 12-17
    • Lu, J.1    Moochhala, S.2    Moore, X.L.3    Ng, C.K.4    Tan, M.H.5    Lee, L.K.H.6    He, B.7    Wong, M.C.8    Ling, E.A.9
  • 46
    • 33847412736 scopus 로고    scopus 로고
    • Treatment of traumatic brain injury with a combination therapy of marrow stromal cells and atorvastatin in rats
    • Mahmood A., Dunyue L., Changsheng Q., Goussev A., Chopp M. Treatment of traumatic brain injury with a combination therapy of marrow stromal cells and atorvastatin in rats. Neurosurgery 2007, 60:546-554.
    • (2007) Neurosurgery , vol.60 , pp. 546-554
    • Mahmood, A.1    Dunyue, L.2    Changsheng, Q.3    Goussev, A.4    Chopp, M.5
  • 47
    • 0942301277 scopus 로고    scopus 로고
    • Intravenous administration of marrow stromal cells (MSCs) increases the expression of growth factors in rat brain after traumatic brain injury
    • Mahmood A., Lu D., Chopp M. Intravenous administration of marrow stromal cells (MSCs) increases the expression of growth factors in rat brain after traumatic brain injury. J. Neurotrauma 2004, 21:33-39.
    • (2004) J. Neurotrauma , vol.21 , pp. 33-39
    • Mahmood, A.1    Lu, D.2    Chopp, M.3
  • 48
    • 8744253481 scopus 로고    scopus 로고
    • Marrow stromal cell transplantation after traumatic brain injury promotes cellular proliferation within the brain
    • Mahmood A., Lu D., Chopp M. Marrow stromal cell transplantation after traumatic brain injury promotes cellular proliferation within the brain. Neurosurgery 2004, 55:1185-1193.
    • (2004) Neurosurgery , vol.55 , pp. 1185-1193
    • Mahmood, A.1    Lu, D.2    Chopp, M.3
  • 49
    • 0041854545 scopus 로고    scopus 로고
    • Treatment of traumatic brain injury in adult rats with intravenous administration of human bone marrow stromal cells
    • Mahmood A., Lu D., Lu M., Chopp M. Treatment of traumatic brain injury in adult rats with intravenous administration of human bone marrow stromal cells. Neurosurgery 2003, 53:697-703.
    • (2003) Neurosurgery , vol.53 , pp. 697-703
    • Mahmood, A.1    Lu, D.2    Lu, M.3    Chopp, M.4
  • 50
    • 27644586801 scopus 로고    scopus 로고
    • Human marrow stromal cell treatment provides long-lasting benefit after traumatic brain injury in rats
    • Mahmood A., Lu D., Qu C., Goussev A., Chopp M. Human marrow stromal cell treatment provides long-lasting benefit after traumatic brain injury in rats. Neurosurgery 2005, 57:1026-1031.
    • (2005) Neurosurgery , vol.57 , pp. 1026-1031
    • Mahmood, A.1    Lu, D.2    Qu, C.3    Goussev, A.4    Chopp, M.5
  • 51
    • 33644509245 scopus 로고    scopus 로고
    • Long-term recovery after bone marrow stromal cell treatment of traumatic brain injury in rats
    • Mahmood A., Lu D., Qu C., Goussev A., Chopp M. Long-term recovery after bone marrow stromal cell treatment of traumatic brain injury in rats. J. Neurosurg. 2006, 104:272-277.
    • (2006) J. Neurosurg. , vol.104 , pp. 272-277
    • Mahmood, A.1    Lu, D.2    Qu, C.3    Goussev, A.4    Chopp, M.5
  • 52
    • 0036922542 scopus 로고    scopus 로고
    • Intracerebral transplantation of marrow stromal cells cultured with neurotrophic factors promotes functional recovery in adult rats subjected to traumatic brain injury
    • Mahmood A., Lu D., Wang L., Chopp M. Intracerebral transplantation of marrow stromal cells cultured with neurotrophic factors promotes functional recovery in adult rats subjected to traumatic brain injury. J. Neurotrauma 2002, 19:1609-1617.
    • (2002) J. Neurotrauma , vol.19 , pp. 1609-1617
    • Mahmood, A.1    Lu, D.2    Wang, L.3    Chopp, M.4
  • 53
    • 0034773785 scopus 로고    scopus 로고
    • Treatment of traumatic brain injury in female rats with intravenous administration of bone marrow stromal cells
    • Mahmood A., Lu D., Wang L., Li Y., Lu M., Chopp M. Treatment of traumatic brain injury in female rats with intravenous administration of bone marrow stromal cells. Neurosurgery 2001, 49:1196-1203.
    • (2001) Neurosurgery , vol.49 , pp. 1196-1203
    • Mahmood, A.1    Lu, D.2    Wang, L.3    Li, Y.4    Lu, M.5    Chopp, M.6
  • 54
    • 0034859794 scopus 로고    scopus 로고
    • Intracranial bone marrow transplantation after traumatic brain injury improving functional outcome in adult rats
    • Mahmood A., Lu D., Yi L., Chen J.L., Chopp M. Intracranial bone marrow transplantation after traumatic brain injury improving functional outcome in adult rats. J. Neurosurg. 2001, 94:589-595.
    • (2001) J. Neurosurg. , vol.94 , pp. 589-595
    • Mahmood, A.1    Lu, D.2    Yi, L.3    Chen, J.L.4    Chopp, M.5
  • 56
    • 0034730470 scopus 로고    scopus 로고
    • Bone marrow: a possible alternative source of cells in the adult nervous system
    • Mezey E., Chandross K.J. Bone marrow: a possible alternative source of cells in the adult nervous system. Eur. J. Pharmacol. 2000, 405:297-302.
    • (2000) Eur. J. Pharmacol. , vol.405 , pp. 297-302
    • Mezey, E.1    Chandross, K.J.2
  • 57
    • 0017626093 scopus 로고
    • Monoaminergic reinnervation of the transected spinal cord by homologous fetal brain grafts
    • Nygren L.G., Olson L., Seiger A. Monoaminergic reinnervation of the transected spinal cord by homologous fetal brain grafts. Brain Res. 1977, 129:227-235.
    • (1977) Brain Res. , vol.129 , pp. 227-235
    • Nygren, L.G.1    Olson, L.2    Seiger, A.3
  • 59
    • 34447502265 scopus 로고    scopus 로고
    • Bone marrow stromal cells in traumatic brain injury (TBI) therapy: true perspective or false hope?
    • Opydo-Chanek M. Bone marrow stromal cells in traumatic brain injury (TBI) therapy: true perspective or false hope?. Acta Neurobiol. Exp. 2007, 67:187-195.
    • (2007) Acta Neurobiol. Exp. , vol.67 , pp. 187-195
    • Opydo-Chanek, M.1
  • 60
    • 70450158749 scopus 로고    scopus 로고
    • Ex vivo-expanded autologous bone marrow-derived mesenchymal stromalcells in human spinal cord injury/paraplegia: a pilot clinical study
    • Pal R., Venkataramana N.K., Bansal A., Balaraju S., Jan M., Chandra R., Dixit A., Rauthan A., Murgod U., Totey S. Ex vivo-expanded autologous bone marrow-derived mesenchymal stromalcells in human spinal cord injury/paraplegia: a pilot clinical study. Cytotherapy 2009, 11:897-911.
    • (2009) Cytotherapy , vol.11 , pp. 897-911
    • Pal, R.1    Venkataramana, N.K.2    Bansal, A.3    Balaraju, S.4    Jan, M.5    Chandra, R.6    Dixit, A.7    Rauthan, A.8    Murgod, U.9    Totey, S.10
  • 62
    • 21844442589 scopus 로고    scopus 로고
    • Treatment of complete spinal cord injury patients by autologous bone marrow cell transplantation and administration of granulocyte-macrophage colony stimulating factor
    • Park H.C., Shims Y.S., Ha Y., Yoon S.H., Park S.R., Choi B.H., Park H.S. Treatment of complete spinal cord injury patients by autologous bone marrow cell transplantation and administration of granulocyte-macrophage colony stimulating factor. Tissue Eng. 2005, 11:913-922.
    • (2005) Tissue Eng. , vol.11 , pp. 913-922
    • Park, H.C.1    Shims, Y.S.2    Ha, Y.3    Yoon, S.H.4    Park, S.R.5    Choi, B.H.6    Park, H.S.7
  • 63
    • 0012027924 scopus 로고    scopus 로고
    • Transplantation of neural progenitors and stem cells: developmental insights may suggest new therapies for spinal cord and other CNS dysfunction
    • Park K.I., Liu S., Flax J.D., Nissim S., Stieg P.E., Snyder E.Y. Transplantation of neural progenitors and stem cells: developmental insights may suggest new therapies for spinal cord and other CNS dysfunction. J. Neurotrauma 1999, 16:675-687.
    • (1999) J. Neurotrauma , vol.16 , pp. 675-687
    • Park, K.I.1    Liu, S.2    Flax, J.D.3    Nissim, S.4    Stieg, P.E.5    Snyder, E.Y.6
  • 64
    • 34648860537 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stromal cells for the repair of central nervous system injury
    • Parr A.M., Tator C.H., Keating A. Bone marrow-derived mesenchymal stromal cells for the repair of central nervous system injury. Bone Marrow Transplant. 2007, 40:609-619.
    • (2007) Bone Marrow Transplant. , vol.40 , pp. 609-619
    • Parr, A.M.1    Tator, C.H.2    Keating, A.3
  • 66
    • 33846503428 scopus 로고    scopus 로고
    • Differentiation assays of bone marrow-derived multipotent adult progenitor cell (MAPC)-like cells towards neural cells cannot depend on morphology and a limited set of neural markers
    • Raedt R., Pinxteren J., Van Dycke A., Waeytems A., Craeye D., Timmermans F., Vonck K., Vandekerckhove B., Plum J., Boon P. Differentiation assays of bone marrow-derived multipotent adult progenitor cell (MAPC)-like cells towards neural cells cannot depend on morphology and a limited set of neural markers. Exp. Neurol. 2007, 203:542-554.
    • (2007) Exp. Neurol. , vol.203 , pp. 542-554
    • Raedt, R.1    Pinxteren, J.2    Van Dycke, A.3    Waeytems, A.4    Craeye, D.5    Timmermans, F.6    Vonck, K.7    Vandekerckhove, B.8    Plum, J.9    Boon, P.10
  • 67
    • 0033757632 scopus 로고    scopus 로고
    • Functional recovery of paraplegic rats and motor axon regeneration in their spinal cords by olfactory ensheating glia
    • Ramón-Cueto A., Cordero M.I., Santos-Benito F.F., Avila J. Functional recovery of paraplegic rats and motor axon regeneration in their spinal cords by olfactory ensheating glia. Neuron 2000, 25:425-435.
    • (2000) Neuron , vol.25 , pp. 425-435
    • Ramón-Cueto, A.1    Cordero, M.I.2    Santos-Benito, F.F.3    Avila, J.4
  • 68
    • 0000635530 scopus 로고    scopus 로고
    • Long-distance axonal regeneration in the transected adult rat spinal cord is promoted by olfactory ensheathing glia transplants
    • Ramón-Cueto A., Plant G.W., Avila J., Bunge M.B. Long-distance axonal regeneration in the transected adult rat spinal cord is promoted by olfactory ensheathing glia transplants. J. Neurosci. 1998, 18:3803-3815.
    • (1998) J. Neurosci. , vol.18 , pp. 3803-3815
    • Ramón-Cueto, A.1    Plant, G.W.2    Avila, J.3    Bunge, M.B.4
  • 70
    • 23844506901 scopus 로고    scopus 로고
    • Cellular transplantation strategies for spinal cord injury and translational neurobiology
    • Reier P.J. Cellular transplantation strategies for spinal cord injury and translational neurobiology. Neurorx 2004, 1:424-451.
    • (2004) Neurorx , vol.1 , pp. 424-451
    • Reier, P.J.1
  • 71
    • 0021880180 scopus 로고
    • Neural tissue grafts and repair of the injured spinal cord
    • Reier P.J. Neural tissue grafts and repair of the injured spinal cord. Neuropathol. Appl. Neurobiol. 1985, 11:81-104.
    • (1985) Neuropathol. Appl. Neurobiol. , vol.11 , pp. 81-104
    • Reier, P.J.1
  • 73
    • 38149140867 scopus 로고    scopus 로고
    • Spinal cord injury treatment with intrathecal autologous bone marrow stromal cell transplantation: the first clinical trial case report
    • Saito F., Nakatani T., Iwase M., Maeda Y., Hirakawa A., Murao Y., Suzuki Y., Onodera R., Fukushima M., Chizuka I. Spinal cord injury treatment with intrathecal autologous bone marrow stromal cell transplantation: the first clinical trial case report. J. Trauma 2008, 64:53-59.
    • (2008) J. Trauma , vol.64 , pp. 53-59
    • Saito, F.1    Nakatani, T.2    Iwase, M.3    Maeda, Y.4    Hirakawa, A.5    Murao, Y.6    Suzuki, Y.7    Onodera, R.8    Fukushima, M.9    Chizuka, I.10
  • 75
    • 13444293278 scopus 로고    scopus 로고
    • Migration of mesenchymal stem cells through cerebrospinal fluid into injured spinal cord tissue
    • Sateke K., Lou J., Lenke L.G. Migration of mesenchymal stem cells through cerebrospinal fluid into injured spinal cord tissue. Spine 2004, 29:1971-1979.
    • (2004) Spine , vol.29 , pp. 1971-1979
    • Sateke, K.1    Lou, J.2    Lenke, L.G.3
  • 76
    • 0029865479 scopus 로고    scopus 로고
    • Combined fetal neural transplantation and nerve growth factor infusion: effects on neurological outcome following fluid-percussion brain injury in the rat
    • Sinson G., Voddi M., McIntosh T.K. Combined fetal neural transplantation and nerve growth factor infusion: effects on neurological outcome following fluid-percussion brain injury in the rat. J. Neurosurg. 1996, 84:655-662.
    • (1996) J. Neurosurg. , vol.84 , pp. 655-662
    • Sinson, G.1    Voddi, M.2    McIntosh, T.K.3
  • 79
    • 79952362601 scopus 로고
    • Maturation of embryonic cerebral tissue grafted into injured spinal cord
    • (Abstract)
    • Vaquero J., Arias A., Martínez R., Oya S., Zurita M. Maturation of embryonic cerebral tissue grafted into injured spinal cord. Acta Neurochir. (Wien) 1992, 117:84. (Abstract).
    • (1992) Acta Neurochir. (Wien) , vol.117 , pp. 84
    • Vaquero, J.1    Arias, A.2    Martínez, R.3    Oya, S.4    Zurita, M.5
  • 80
    • 0026600139 scopus 로고
    • Delayed transplantation of foetal cerebral tissue into injured spinal cord of adult rats
    • Vaquero J., Arias A., Oya S., Coca S., Zurita M. Delayed transplantation of foetal cerebral tissue into injured spinal cord of adult rats. Acta Neurochir. (Wien) 1992, 115:133-142.
    • (1992) Acta Neurochir. (Wien) , vol.115 , pp. 133-142
    • Vaquero, J.1    Arias, A.2    Oya, S.3    Coca, S.4    Zurita, M.5
  • 81
    • 33646366471 scopus 로고    scopus 로고
    • Cell therapy using bone marrow stromal cells in chronic paraplegic rats: systemic or local administration?
    • Vaquero J., Zurita M., Oya S., Santos M. Cell therapy using bone marrow stromal cells in chronic paraplegic rats: systemic or local administration?. Neurosci. Lett. 2006, 398:129-134.
    • (2006) Neurosci. Lett. , vol.398 , pp. 129-134
    • Vaquero, J.1    Zurita, M.2    Oya, S.3    Santos, M.4
  • 82
    • 0023737839 scopus 로고
    • Immunological aspects of grafting in the mammalian central nervous system. A review and speculative synthesis
    • Widner H., Brundin P. Immunological aspects of grafting in the mammalian central nervous system. A review and speculative synthesis. Brain Res. 1988, 472:287-324.
    • (1988) Brain Res. , vol.472 , pp. 287-324
    • Widner, H.1    Brundin, P.2
  • 84
    • 0034589738 scopus 로고    scopus 로고
    • Immortalized neural cell lines for CNS transplantation
    • Whittemore S.R., Onifer S.M. Immortalized neural cell lines for CNS transplantation. Prog. Brain Res. 2000, 127:49-65.
    • (2000) Prog. Brain Res. , vol.127 , pp. 49-65
    • Whittemore, S.R.1    Onifer, S.M.2
  • 85
    • 0034663515 scopus 로고    scopus 로고
    • Adult rat and human bone marrow stromal cells differentiate into neurons
    • Woodbury D., Schwar E.J., Prockop D.J., Black I.B. Adult rat and human bone marrow stromal cells differentiate into neurons. J. Neurosci. Res. 2000, 61:364-370.
    • (2000) J. Neurosci. Res. , vol.61 , pp. 364-370
    • Woodbury, D.1    Schwar, E.J.2    Prockop, D.J.3    Black, I.B.4
  • 86
    • 0020032468 scopus 로고
    • Reconstruction of the contused cat spinal cord by the delayed nerve graft technique and cultured peripheral non-neuronal cells
    • Wrathall J.R., Rigamonti D.D., Braford M.R., Kao C.C. Reconstruction of the contused cat spinal cord by the delayed nerve graft technique and cultured peripheral non-neuronal cells. Acta Neuropathol. (Berl.) 1982, 57:59-69.
    • (1982) Acta Neuropathol. (Berl.) , vol.57 , pp. 59-69
    • Wrathall, J.R.1    Rigamonti, D.D.2    Braford, M.R.3    Kao, C.C.4
  • 87
    • 34347221895 scopus 로고    scopus 로고
    • Embryonic stem cell transplantation: potential applicability in cell replacement therapy and regenerative medicine
    • Wu D.C., Boyd A.S., Wood K.J. Embryonic stem cell transplantation: potential applicability in cell replacement therapy and regenerative medicine. Front. Biosci. 2007, 12:4525-4535.
    • (2007) Front. Biosci. , vol.12 , pp. 4525-4535
    • Wu, D.C.1    Boyd, A.S.2    Wood, K.J.3
  • 88
    • 17844362430 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor in bone marrow stromal cells of rat
    • Ye M., Chen S., Wang X., Qi C., Lu G., Liang L., Xu J. Glial cell line-derived neurotrophic factor in bone marrow stromal cells of rat. Neuroreport 2005, 16:581-584.
    • (2005) Neuroreport , vol.16 , pp. 581-584
    • Ye, M.1    Chen, S.2    Wang, X.3    Qi, C.4    Lu, G.5    Liang, L.6    Xu, J.7
  • 89
    • 34547915244 scopus 로고    scopus 로고
    • Complete spinal cord injury treatment using autologous bone marrow cell transplantation and bone marrow stimulation with granulocyte-macrophage-colony stimulating factor: phase I/II clinical trial
    • Yoon S.H., Shim Y.S., Park Y.H., Chung J.K., Nam J.H., Kim M.O., Park H.C., Park S.R., Min B.H., Kim E.Y., Choi B.H., Park H., Ha Y. Complete spinal cord injury treatment using autologous bone marrow cell transplantation and bone marrow stimulation with granulocyte-macrophage-colony stimulating factor: phase I/II clinical trial. Stem Cells 2007, 25:2066-2073.
    • (2007) Stem Cells , vol.25 , pp. 2066-2073
    • Yoon, S.H.1    Shim, Y.S.2    Park, Y.H.3    Chung, J.K.4    Nam, J.H.5    Kim, M.O.6    Park, H.C.7    Park, S.R.8    Min, B.H.9    Kim, E.Y.10    Choi, B.H.11    Park, H.12    Ha, Y.13
  • 94
    • 77954454266 scopus 로고    scopus 로고
    • Cell therapy for spinal cord repair: optimization of biologic scaffolds for survival and neural differentiation of human bone marrow stromal cells
    • Zurita M., Otero L., Aguayo C., Bonilla C., Ferreira E., Parajon A., Vaquero J. Cell therapy for spinal cord repair: optimization of biologic scaffolds for survival and neural differentiation of human bone marrow stromal cells. Cytotherapy 2010, 12:522-537.
    • (2010) Cytotherapy , vol.12 , pp. 522-537
    • Zurita, M.1    Otero, L.2    Aguayo, C.3    Bonilla, C.4    Ferreira, E.5    Parajon, A.6    Vaquero, J.7
  • 95
    • 2442656364 scopus 로고    scopus 로고
    • Functional recovery in chronic paraplegia after bone marrow stromal cells transplantation
    • Zurita M., Vaquero J. Functional recovery in chronic paraplegia after bone marrow stromal cells transplantation. Neuroreport 2004, 15:1105-1108.
    • (2004) Neuroreport , vol.15 , pp. 1105-1108
    • Zurita, M.1    Vaquero, J.2
  • 96
    • 33646871027 scopus 로고    scopus 로고
    • Bone marrow stromal cells can achieve cure of chronic paraplegic rats: functional and morphological outcome one year after transplantation
    • Zurita M., Vaquero J. Bone marrow stromal cells can achieve cure of chronic paraplegic rats: functional and morphological outcome one year after transplantation. Neurosci. Lett. 2006, 402:51-56.
    • (2006) Neurosci. Lett. , vol.402 , pp. 51-56
    • Zurita, M.1    Vaquero, J.2
  • 97
    • 56049103562 scopus 로고    scopus 로고
    • Functional recovery of chronic paraplegic pigs after autologous transplantation of bone marrow stromal cells
    • Zurita M., Vaquero J., Bonilla C., Santos M., De Haro J., Oya S., Aguayo C. Functional recovery of chronic paraplegic pigs after autologous transplantation of bone marrow stromal cells. Transplantation 2008, 86:845-853.
    • (2008) Transplantation , vol.86 , pp. 845-853
    • Zurita, M.1    Vaquero, J.2    Bonilla, C.3    Santos, M.4    De Haro, J.5    Oya, S.6    Aguayo, C.7
  • 98
    • 16444382118 scopus 로고    scopus 로고
    • Schwann cells induce neuronal differentiation of bone marrow stromal cells
    • Zurita M., Vaquero J., Oya S., Miguel M. Schwann cells induce neuronal differentiation of bone marrow stromal cells. Neuroreport 2005, 16:505-508.
    • (2005) Neuroreport , vol.16 , pp. 505-508
    • Zurita, M.1    Vaquero, J.2    Oya, S.3    Miguel, M.4
  • 99
    • 0034971308 scopus 로고    scopus 로고
    • Functional recovery in chronic paraplegic rats after co-grafts of fetal brain and adult peripheral nerve tissue
    • Zurita M., Vaquero J., Oya S., Montilla J. Functional recovery in chronic paraplegic rats after co-grafts of fetal brain and adult peripheral nerve tissue. Surg. Neurol. 2001, 55:249-254.
    • (2001) Surg. Neurol. , vol.55 , pp. 249-254
    • Zurita, M.1    Vaquero, J.2    Oya, S.3    Montilla, J.4
  • 100
    • 0033756860 scopus 로고    scopus 로고
    • Grafting of neural tissue in chronically injured spinal cord: influence of the donor tissue on regenerative activity
    • Zurita M., Vaquero J., Oya S. Grafting of neural tissue in chronically injured spinal cord: influence of the donor tissue on regenerative activity. Surg. Neurol. 2000, 54:117-125.
    • (2000) Surg. Neurol. , vol.54 , pp. 117-125
    • Zurita, M.1    Vaquero, J.2    Oya, S.3


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