Intracranial bone marrow transplantation after traumatic brain injury improving functional outcome in adult rats

Journal of Neurosurgery

Volumn 94, Issue 4, 2001, Pages 589-595

  Mahmood, A ^a   Lu, D ^a   Li, Y ^a   Chen, J L ^a   Chopp, M ^a  

^a HENRY FORD HOSPITAL   (United States)

Author keywords

Bone marrow; Rat; Transplantation; Traumatic brain injury

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; NEU DIFFERENTIATION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BONE MARROW TRANSPLANTATION; BRAIN CONTUSION; BRAIN INJURY; BRAIN SURGERY; CELL SURVIVAL; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; MALE; MOTOR PERFORMANCE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TREATMENT OUTCOME;

EID: 0034859794     PISSN: 00223085     EISSN: None     Source Type: Journal    
DOI: 10.3171/jns.2001.94.4.0589     Document Type: Article

References (69)

1. Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats - Similarities to astrocyte grafts
2. Trophism, transplantation and animal models of Parkinson's disease
3. Diagnosis and treatment of head injury in adults
4. Neural transplantation - An experimental tool with clinical possibilities
5. Cell replacement therapies for central nervous system disorders
6. CNS immunological modulation of neural graft rejection and survival
7. Current status of neuroprotection trials for traumatic brain injury: Lessons from animal models and clinical studies
8. Immuno-electron microscopy characterization of human bone marrow stromal cells with anti-NGFR antibodies
9. Intracerebral transplantation of bone marrow with BDNF after MCAo in rat
10. Differentiation of human bone marrow osteogenic stromal cells in vitro: Induction of the osteoblast phenotype by dexamethasone
11. Post ischemic administration of an anti-Mac-1 antibody reduces ischemic cell damage after transient middle cerebral artery occlusion in the rat
12. Biology of bone marrow stroma
13. Neutrophil accumulation after traumatic brain injury in rats: Comparison of weight drop and controlled cortical impact model
14. Uber entzündung und eiterung
15. Determination of the origin and nature of brain macrophages and microglial cells in mouse central nervous system, using non-radioactive in situ hybridization and immunoperoxidase techniques
16. A controlled cortical impact model of traumatic brain injury in rat
17. Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. II. Analysis of positive and negative regulators produced by stromal cells within the adherent layer
18. Targeting of marrow-derived astrocytes to the ischemic brain
19. Hematopoietic cells differentiate into both microglia and macroglia in the brains of adult mice
20. Implants of encapsulated human CNTF-producing fibroblasts prevent behavioral deficits and striatal degeneration in a rodent model of Huntington's disease
21. Differential expression of neural cell adhesion molecule (NCAM) during osteogenesis and secondary chondrogenesis in the embryonic chick
22. Grafting in the mammalian central nervous system
23. Bone marrow osteogenic stem cells: In vitro cultivation and transplantation in diffusion chambers
24. Morphological response of axotomized septal neurons to nerve growth factor
25. Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain
26. Transplantation into the Mammalian CNS
27. Globin gene expression is reprogrammed in chimeras generated by injecting adult hematopoietic stem cells into mouse blastocysts
28. GABA receptor agonist promotes reformation of the striatonigral pathway by transplant derived from fetal striatal primordia in the lesioned striatum
29. Ciliary neurotrophic factor prevents neuronal degeneration and promotes low affinity NGF receptor expression in adult rat CNS
30. The Rotarod test: An evaluation of its effectiveness in assessing motor deficits following traumatic brain injury
31. Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections
32. Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo
33. Somatic gene transfer of nerve growth factor promotes the survival of axotomized septal neurons and the regeneration of their axons in adult rats
34. Apoptosis and expression of p53 response proteins and cyclin D1 after cortical impact in rat brain
35. Expression of cell cycle proteins (cyclin D1 and cdk4) after controlled cortical impact in rat brain
36. Expression of nestin after traumatic brain injury in rat brain
37. Kinetics of central nervous system microglial and macrophage engraftment: Analysis using a transgenic bone marrow transplantation model
38. Evidence that brain-derived neurotrophic factor is atrophic factor for motor neurons in vivo
39. Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains
40. Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease
41. Cells expressing human glucocerebrosidase from a retroviral vector repopulate macrophages and central nervous system microglia after murine bone marrow transplantation
42. Nerve growth factor treatment after brain injury prevents neuronal death
43. Six month follow-up of motor function after fetal transplantation in a patient with Huntington's disease
44. Expression of neurotrophins and their receptors in human bone marrow
45. The problem of neuronal regeneration in the central nervous system. I. The influence of spinal ganglia and nerve fragments grafted in the brain
46. Neurotrophic agents prevent motorneuron death following sciatic nerve section in the neonatal mouse
47. Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MSCs) and stromal cells
48. The hematopoietic cytokine colony stimulating factor 1 is also a growth factor in the CNS: (II) microencapsulated CSF-1 and LM-10 cells as delivery systems
49. Cytokine regulation of neuronal differentiation of hippocampal progenitor cells
50. Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage and lung in irradiated mice
51. Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta
52. A calpain inhibitor attenuates cortical cytoskeletal protein loss after experimental traumatic brain injury in the rat
53. Marrow stromal cells as stem cells for nonhematopoietic tissues
54. Transplantation of the spinal ganglion, with observations on the significance of the complex types of spinal ganglion cells
55. Neural tissue transplantation and CNS trauma: Anatomical and functional repair of the injured spinal cord
56. The fountain of youth: Can it be transplanted?
57. Phenotypic and functional characterization of the hematopoietic stem cell
58. Multipotent neural cell lines can engraft and participate in development of mouse cerebellum
59. Multipotent neural precursors can differentiate toward replacement of neurons undergoing targeted apoptotic degeneration in adult mouse neocortex
60. Fetal cortical transplants in adult rats subjected to experimental brain injury
61. Hippocampal transplants attenuate CA3 pyramidal cell death resulting from fluid percussion brain injury in the rat
62. Oxygen transport in intraspinal fetal grafts-graft-host relations
63. Successful brain grafting
64. The transplantation of spinal ganglia in the white rat. A study of the morphological changes in surviving cells
65. Myogenic cells derived from rat bone marrow mesenchymal stem cells exposed to 5-azacytidine
66. Bone marrow transplantation corrects the enzyme defect in neurons of the central nervous system in a lysosomal storage disease