-
1
-
-
34047207337
-
TP53 mutations in human cancers: Functional selection and impact on cancer prognosis and outcomes. Review
-
Petitjean A, Achatz MI, Borresen-Dale AL, Hainaut P, Olivier M (2002) TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes. Review. Oncogene 26(15): 2157-2165.
-
(2002)
Oncogene
, vol.26
, Issue.15
, pp. 2157-2165
-
-
Petitjean, A.1
Achatz, M.I.2
Borresen-Dale, A.L.3
Hainaut, P.4
Olivier, M.5
-
2
-
-
0036674617
-
Live or let die: The cell's response to p53
-
Vousden KH, Lu X (2002) Live or let die: the cell's response to p53. Nat Rev Cancer 2: 594-604.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
3
-
-
70349443284
-
When mutants gain new powers: News from the mutant p53 field
-
Brosh R, Rotter V (2009) When mutants gain new powers: news from the mutant p53 field. Nat Rev Cancer 9(10): 701-713.
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.10
, pp. 701-713
-
-
Brosh, R.1
Rotter, V.2
-
4
-
-
0030905284
-
Mdm2 promotes the rapid degradation of p53
-
Haupt Y, Maya R, Kazaz A, Oren M (1997) Mdm2 promotes the rapid degradation of p53. Nature 387: 296-299.
-
(1997)
Nature
, vol.387
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
5
-
-
0029914660
-
Overexpression of the MDM2 oncogene in leukemia and lymphoma
-
Watanabe T, Ichikawa A, Saito H, Hotta T (1996) Overexpression of the MDM2 oncogene in leukemia and lymphoma. Leuk Lymphoma 21: 391-397.
-
(1996)
Leuk Lymphoma
, vol.21
, pp. 391-397
-
-
Watanabe, T.1
Ichikawa, A.2
Saito, H.3
Hotta, T.4
-
6
-
-
0035100156
-
MDM2 gene amplification and lack of p53 point mutations in Hodgkin and Reed-Sternberg cells: Results from single-cell polymerase chain reaction and molecular cytogenetic studies
-
Küpper M, Joos S, von Bonin F, Daus H, Pfreundschuh M, et al. (2001) MDM2 gene amplification and lack of p53 point mutations in Hodgkin and Reed-Sternberg cells: results from single-cell polymerase chain reaction and molecular cytogenetic studies. Br J Haematol 112: 768-775.
-
(2001)
Br J Haematol
, vol.112
, pp. 768-775
-
-
Küpper, M.1
Joos, S.2
von Bonin, F.3
Daus, H.4
Pfreundschuh, M.5
-
7
-
-
25444519182
-
Pharmacologic modulation of glycogen synthase kinase-3beta promotes p53-dependent apoptosis through a direct Bax-mediated mitochondrial pathway in colorectal cancer cells
-
Tan J, Zhuang L, Leong HS, Iyer NG, Liu ET, et al. (2005) Pharmacologic modulation of glycogen synthase kinase-3beta promotes p53-dependent apoptosis through a direct Bax-mediated mitochondrial pathway in colorectal cancer cells. Cancer Res 65(19): 9012-9020.
-
(2005)
Cancer Res
, vol.65
, Issue.19
, pp. 9012-9020
-
-
Tan, J.1
Zhuang, L.2
Leong, H.S.3
Iyer, N.G.4
Liu, E.T.5
-
8
-
-
0033212125
-
ATM: The protein encoded by the gene mutated in the radiosensitive syndrome ataxia-telangiectasia
-
Lavin MF, Khanna KK (1999) ATM: the protein encoded by the gene mutated in the radiosensitive syndrome ataxia-telangiectasia. Int J Radiat Biol 75(10): 1201-1214.
-
(1999)
Int J Radiat Biol
, vol.75
, Issue.10
, pp. 1201-1214
-
-
Lavin, M.F.1
Khanna, K.K.2
-
9
-
-
0029049828
-
Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumours
-
Moll UM, LaQuaglia M, Bénard J, Riou G (1995) Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumours. Proc Natl Acad Sci USA 92: 4407-4411.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 4407-4411
-
-
Moll, U.M.1
Laquaglia, M.2
Bénard, J.3
Riou, G.4
-
10
-
-
79959503826
-
The Internation HapMap project
-
The International HapMap Consortium
-
The International HapMap Consortium (2003) The Internation HapMap project. Nature 426: 789-796.
-
(2003)
Nature
, vol.426
, pp. 789-796
-
-
-
11
-
-
0032878145
-
Intron variants of the p53 gene are associated with increased risk for ovarian cancer but not in carriers of BRCA1 or BRCA2 germline mutations
-
Wang-Gohrke S, Weikel W, Risch H, Vesprini D, Abrahamson J, et al. (1999) Intron variants of the p53 gene are associated with increased risk for ovarian cancer but not in carriers of BRCA1 or BRCA2 germline mutations. Br J Cancer 81(1): 179-183.
-
(1999)
Br J Cancer
, vol.81
, Issue.1
, pp. 179-183
-
-
Wang-Gohrke, S.1
Weikel, W.2
Risch, H.3
Vesprini, D.4
Abrahamson, J.5
-
12
-
-
11144356056
-
A TP53 polymorphism is associated with increased risk of colorectal cancer and with reduced levels of TP53 mRNA. Germ line polymorphisms of the tumor suppressor gene p53 and lung cancer
-
Gemignani F, Moreno V, Landi S, Moullan N, Chabrier A, et al. (2004) A TP53 polymorphism is associated with increased risk of colorectal cancer and with reduced levels of TP53 mRNA. Germ line polymorphisms of the tumor suppressor gene p53 and lung cancer. Oncogene 23(10): 1954-1956.
-
(2004)
Oncogene
, vol.23
, Issue.10
, pp. 1954-1956
-
-
Gemignani, F.1
Moreno, V.2
Landi, S.3
Moullan, N.4
Chabrier, A.5
-
13
-
-
0035144804
-
Germ line polymorphisms of the tumor suppressor gene p53 and lung cancer
-
Biros E, Kalina I, Kohút A, Stubna J, Salagovic J (2001) Germ line polymorphisms of the tumor suppressor gene p53 and lung cancer. Lung Cancer 31(2-3): 157-162.
-
(2001)
Lung Cancer
, vol.31
, Issue.2-3
, pp. 157-162
-
-
Biros, E.1
Kalina, I.2
Kohút, A.3
Stubna, J.4
Salagovic, J.5
-
14
-
-
0034652588
-
Elevated frequency and functional activity of a specific germ-line p53 intron mutation in familial breast cancer
-
Lehman TA, Haffty BG, Carbone CJ, Bishop LR, Gumbs AA, et al. (2000) Elevated frequency and functional activity of a specific germ-line p53 intron mutation in familial breast cancer. Cancer Res 60(4): 1062-1069.
-
(2000)
Cancer Res
, vol.60
, Issue.4
, pp. 1062-1069
-
-
Lehman, T.A.1
Haffty, B.G.2
Carbone, C.J.3
Bishop, L.R.4
Gumbs, A.A.5
-
17
-
-
27744528095
-
Evidence for selective expression of the p53 codon 72 polymorphs: Implications in cancer development. Cancer Epidemiol
-
Siddique MM, Balram C, Fiszer-Maliszewska L, Aggarwal A, Tan A, et al. (2005) Evidence for selective expression of the p53 codon 72 polymorphs: implications in cancer development. Cancer Epidemiol. Biomarkers Prev 14: 2245-2252.
-
(2005)
Biomarkers Prev
, vol.14
, pp. 2245-2252
-
-
Siddique, M.M.1
Balram, C.2
Fiszer-Maliszewska, L.3
Aggarwal, A.4
Tan, A.5
-
18
-
-
41849110219
-
MDM2 SNP309G allele increases risk but the T allele is associated with earlier onset age of sporadic breast cancers in the Chinese population
-
Lum SS, Chua HW, Li H, Li WF, Rao N, et al. (2008) MDM2 SNP309G allele increases risk but the T allele is associated with earlier onset age of sporadic breast cancers in the Chinese population. Carcinogenesis 29(4): 754-761.
-
(2008)
Carcinogenesis
, vol.29
, Issue.4
, pp. 754-761
-
-
Lum, S.S.1
Chua, H.W.2
Li, H.3
Li, W.F.4
Rao, N.5
-
19
-
-
34548575637
-
Association of TP53 codon 72 polymorphism and the outcome of adjuvant therapy in breast cancer patients
-
Toyama T, Zhang Z, Nishio M, Hamaguchi M, Kondo N, et al. (2007) Association of TP53 codon 72 polymorphism and the outcome of adjuvant therapy in breast cancer patients. Breast Cancer Res 9: R34.
-
(2007)
Breast Cancer Res
, vol.9
-
-
Toyama, T.1
Zhang, Z.2
Nishio, M.3
Hamaguchi, M.4
Kondo, N.5
-
20
-
-
33846585408
-
Polymorphism of TP53 codon 72 showed no association with breast cancer in Iranian women. Cancer Genet
-
Khadang B, Fattahi MJ, Talei A, Dehaghani AS, Ghaderi A (2007) Polymorphism of TP53 codon 72 showed no association with breast cancer in Iranian women. Cancer Genet. Cytogenet 173: 38-42.
-
(2007)
Cytogenet
, vol.173
, pp. 38-42
-
-
Khadang, B.1
Fattahi, M.J.2
Talei, A.3
Dehaghani, A.S.4
Ghaderi, A.5
-
22
-
-
34548242532
-
Evidence for an association of TP53 codon 72 polymorphism with breast cancer risk
-
Damin AP, Frazzon AP, Damin DC, Roehe A, Hermes V, et al. (2006) Evidence for an association of TP53 codon 72 polymorphism with breast cancer risk. Cancer Detect Prev 30: 523-529.
-
(2006)
Cancer Detect Prev
, vol.30
, pp. 523-529
-
-
Damin, A.P.1
Frazzon, A.P.2
Damin, D.C.3
Roehe, A.4
Hermes, V.5
-
23
-
-
10744231895
-
No evidence of correlation between p53 codon 72 polymorphism and risk of bladder or breast carcinoma in Tunisian patients
-
Mabrouk I, Baccouche S, El-Abed R, Mokdad-Gargouri R, Mosbah A, et al. (2003) No evidence of correlation between p53 codon 72 polymorphism and risk of bladder or breast carcinoma in Tunisian patients. Ann N Y Acad Sci 1010: 764-770.
-
(2003)
Ann N Y Acad Sci
, vol.1010
, pp. 764-770
-
-
Mabrouk, I.1
Baccouche, S.2
El-Abed, R.3
Mokdad-Gargouri, R.4
Mosbah, A.5
-
24
-
-
0642314312
-
P53 codon 72 polymorphism in breast cancer
-
Buyru N, Tigli H, Dalay N (2003) P53 codon 72 polymorphism in breast cancer. Oncol Rep 10: 711-714.
-
(2003)
Oncol Rep
, vol.10
, pp. 711-714
-
-
Buyru, N.1
Tigli, H.2
Dalay, N.3
-
25
-
-
0036566749
-
p53 Genotypes and haplotypes associated with lung cancer susceptibility and ethnicity
-
Wu X, Zhao H, Amos CI, Shete S, Makan N, et al. (2002) p53 Genotypes and haplotypes associated with lung cancer susceptibility and ethnicity. J Natl Cancer Inst 94: 681-690.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 681-690
-
-
Wu, X.1
Zhao, H.2
Amos, C.I.3
Shete, S.4
Makan, N.5
-
26
-
-
0032900988
-
p53 codon 72 polymorphism in Taiwanese lung cancer patients: Association with lung cancer susceptibility and prognosis
-
Wang YC, Chen CY, Chen SK, Chang YY, Lin P (1999) p53 codon 72 polymorphism in Taiwanese lung cancer patients: association with lung cancer susceptibility and prognosis. Clin Cancer Res 5: 129-134.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 129-134
-
-
Wang, Y.C.1
Chen, C.Y.2
Chen, S.K.3
Chang, Y.Y.4
Lin, P.5
-
27
-
-
0028339379
-
Is p53 polymorphism maintained by natural selection? Hum
-
Beckman G, Birgander R, Sjalander A, Saha N, Holmberg PA, et al. (1994) Is p53 polymorphism maintained by natural selection? Hum. Hered 44: 266-270.
-
(1994)
Hered
, vol.44
, pp. 266-270
-
-
Beckman, G.1
Birgander, R.2
Sjalander, A.3
Saha, N.4
Holmberg, P.A.5
-
28
-
-
0037372005
-
The codon 72 polymorphic variants of p53 have markedly different apoptotic potential
-
Dumont P, Leu JI, Della Pietra AC, 3rd, George DL, Murphy M (2003) The codon 72 polymorphic variants of p53 have markedly different apoptotic potential. Nat Genet 33: 357-365.
-
(2003)
Nat Genet
, vol.33
, pp. 357-365
-
-
Dumont, P.1
Leu, J.I.2
PietraIII., D.A.C.3
George, D.L.4
Murphy, M.5
-
29
-
-
33745116207
-
Trp53-dependent DNA-repair is affected by the codon 72 polymorphism
-
Siddique M, Sabapathy K (2006) Trp53-dependent DNA-repair is affected by the codon 72 polymorphism. Oncogene 25: 3489-3500.
-
(2006)
Oncogene
, vol.25
, pp. 3489-3500
-
-
Siddique, M.1
Sabapathy, K.2
-
30
-
-
0346121357
-
P53 polymorphic variants at codon 72 exert different effects on cell cycle progression
-
Pim D, Banks L (2004) P53 polymorphic variants at codon 72 exert different effects on cell cycle progression. Int J Cancer 108: 196-199.
-
(2004)
Int J Cancer
, vol.108
, pp. 196-199
-
-
Pim, D.1
Banks, L.2
-
31
-
-
33749118677
-
iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72-polymorphic p53
-
Bergamaschi D, Samuels Y, Sullivan A, Zvelebil M, Breyssens H, et al. (2006) iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72-polymorphic p53. Nat Genet;10): 1133-1141.
-
(2006)
Nat Genet
, vol.10
, pp. 1133-1141
-
-
Bergamaschi, D.1
Samuels, Y.2
Sullivan, A.3
Zvelebil, M.4
Breyssens, H.5
-
32
-
-
40849112781
-
MDM2 SNP309 G allele decreases risk but does not affect onset age or survival of Chinese leukaemia patients
-
Phang BH, Linn YC, Li H, Sabapathy K (2008) MDM2 SNP309 G allele decreases risk but does not affect onset age or survival of Chinese leukaemia patients. Eur J Cancer 44: 760-766.
-
(2008)
Eur J Cancer
, vol.44
, pp. 760-766
-
-
Phang, B.H.1
Linn, Y.C.2
Li, H.3
Sabapathy, K.4
-
33
-
-
77949476980
-
Effect of MDM2 SNP309 and p53 codon 72 polymorphisms on lung cancer risk and survival among nonsmoking Chinese women in Singapore
-
Chua HW, Ng D, Choo S, Lum SS, Li H, et al. (2010) Effect of MDM2 SNP309 and p53 codon 72 polymorphisms on lung cancer risk and survival among nonsmoking Chinese women in Singapore. BMC Cancer 10: 88.
-
(2010)
BMC Cancer
, vol.10
, pp. 88
-
-
Chua, H.W.1
Ng, D.2
Choo, S.3
Lum, S.S.4
Li, H.5
-
34
-
-
0025738781
-
Biallelic Apal polymorphism of the human p53 gene (TP53)
-
Prosser J, Condie A (1991) Biallelic Apal polymorphism of the human p53 gene (TP53). Nucleic Acids Res 19: 4799.
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 4799
-
-
Prosser, J.1
Condie, A.2
-
35
-
-
34250815628
-
Study on the relationship between the polymorphism of p53 gene intron 7 and non-small cell lung cancer (NSCLC) and p53 mutation in NSCLC tissues
-
Gu QH, Chen Q, Hu CP, Li YQ, Yang HZ (2007) Study on the relationship between the polymorphism of p53 gene intron 7 and non-small cell lung cancer (NSCLC) and p53 mutation in NSCLC tissues. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 24(3): 319-321.
-
(2007)
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
, vol.24
, Issue.3
, pp. 319-321
-
-
Gu, Q.H.1
Chen, Q.2
Hu, C.P.3
Li, Y.Q.4
Yang, H.Z.5
-
36
-
-
44349108194
-
p53 gene intron 7 polymorphism and its association with oral neoplasms
-
Li YQ, Li YL, Gu H, Ye AH, Wu TS (2005) p53 gene intron 7 polymorphism and its association with oral neoplasms. Zhonghua Kou Qiang Yi Xue Za Zhi 40(5): 386-389.
-
(2005)
Zhonghua Kou Qiang Yi Xue Za Zhi
, vol.40
, Issue.5
, pp. 386-389
-
-
Li, Y.Q.1
Li, Y.L.2
Gu, H.3
Ye, A.H.4
Wu, T.S.5
-
37
-
-
34547577319
-
p53 and its isoforms in cancer
-
Bourdon JC (2007) p53 and its isoforms in cancer. Br J Cancer 97(3): 277-282.
-
(2007)
Br J Cancer
, vol.97
, Issue.3
, pp. 277-282
-
-
Bourdon, J.C.1
-
38
-
-
0346373654
-
Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium
-
Carlson CS, Eberke MA, Rieder MJ, Yi Q, Kruglyak L, et al. (2004) Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium. Am J Hum Genet 74: 106-120.
-
(2004)
Am J Hum Genet
, vol.74
, pp. 106-120
-
-
Carlson, C.S.1
Eberke, M.A.2
Rieder, M.J.3
Yi, Q.4
Kruglyak, L.5
-
39
-
-
13444269543
-
Haploview: Analysis and visualization of LD and haplotype maps
-
Barrett JC, Fry B, Maller J, Daly MJ (2005) Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21(2): 263-265.
-
(2005)
Bioinformatics
, vol.21
, Issue.2
, pp. 263-265
-
-
Barrett, J.C.1
Fry, B.2
Maller, J.3
Daly, M.J.4
-
40
-
-
34548292504
-
PLINK: A toolset for whole-genome association and population-based linkage analysis
-
Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MAR, et al. (2007) PLINK: a toolset for whole-genome association and population-based linkage analysis. Am J Hum Genet 81: 559-575.
-
(2007)
Am J Hum Genet
, vol.81
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
Thomas, L.4
Ferreira, M.A.R.5
|