MDM2 gene amplification and lack of p53 point mutations in Hodgkin and Reed-Sternberg cells: Results from single-cell polymerase chain reaction and molecular cytogenetic studies

British Journal of Haematology

Volumn 112, Issue 3, 2001, Pages 768-775

  Küpper, Manfred ^a,b   Joos, Stefan ^b   Von Bonin, Frederike ^a   Daus, Heiner ^a   Pfreundschuh, Michael ^a   Lichter, Peter ^b   Trümper, Lorenz ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

CGH; FISH; Hodgkin's disease; MDM2; p53

Indexed keywords

PROTEIN MDM2; PROTEIN P53;

ADULT; ARTICLE; CANCER GENETICS; CHROMOSOME 12Q; CLINICAL ARTICLE; COMPARATIVE GENOMIC HYBRIDIZATION; CYTOGENETICS; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE MAPPING; GENE OVEREXPRESSION; GENETIC SCREENING; HODGKIN DISEASE; HUMAN; HUMAN CELL; MALE; MOLECULAR GENETICS; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REED STERNBERG CELL;

ADULT; CYTOGENETIC ANALYSIS; FEMALE; GENE AMPLIFICATION; GENES, P53; HODGKIN DISEASE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; MIDDLE AGED; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; REED-STERNBERG CELLS;

EID: 0035100156     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2001.02566.x     Document Type: Article

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