-
1
-
-
0037037822
-
The p53 network in lung carcinogenesis
-
10.1038/sj.onc.1205563, 12362272
-
Robles AI, Linke SP, Harris CC. The p53 network in lung carcinogenesis. Oncogene 2002, 21:6898-907. 10.1038/sj.onc.1205563, 12362272.
-
(2002)
Oncogene
, vol.21
, pp. 6898-6907
-
-
Robles, A.I.1
Linke, S.P.2
Harris, C.C.3
-
2
-
-
0030905284
-
Mdm2 promotes the rapid degradation of p53
-
10.1038/387296a0, 9153395
-
Haupt Y, Maya R, Kazaz A, Oren M. Mdm2 promotes the rapid degradation of p53. Nature 1997, 387:296-9. 10.1038/387296a0, 9153395.
-
(1997)
Nature
, vol.387
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
3
-
-
8844278362
-
A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans
-
10.1016/j.cell.2004.11.022, 15550242
-
Bond GL, Hu W, Bond EE, Robins H, Lutzker SG, Arva NC, Bargonetti J, Bartel F, Taubert H, Wuerl P, Onel K, Yip L, et al. A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans. Cell 2004, 119:591-602. 10.1016/j.cell.2004.11.022, 15550242.
-
(2004)
Cell
, vol.119
, pp. 591-602
-
-
Bond, G.L.1
Hu, W.2
Bond, E.E.3
Robins, H.4
Lutzker, S.G.5
Arva, N.C.6
Bargonetti, J.7
Bartel, F.8
Taubert, H.9
Wuerl, P.10
Onel, K.11
Yip, L.12
-
4
-
-
21344470650
-
A single nucleotide polymorphism in the MDM2 gene: from a molecular and cellular explanation to clinical effect
-
10.1158/0008-5472.CAN-05-0825, 15994915
-
Bond GL, Hu W, Levine A. A single nucleotide polymorphism in the MDM2 gene: from a molecular and cellular explanation to clinical effect. Cancer Res 2005, 65:5481-4. 10.1158/0008-5472.CAN-05-0825, 15994915.
-
(2005)
Cancer Res
, vol.65
, pp. 5481-5484
-
-
Bond, G.L.1
Hu, W.2
Levine, A.3
-
5
-
-
43749092215
-
Early onset lung cancer, cigarette smoking and the SNP309 of the murine double minute-2 (MDM2) gene
-
10.1186/1471-2407-8-113, 2377274, 18433484
-
Mittelstrass K, Sauter W, Rosenberger A, Illig T, Timofeeva M, Klopp N, Dienemann H, Meese E, Sybrecht G, Woelke G, Cebulla M, Degen M, et al. Early onset lung cancer, cigarette smoking and the SNP309 of the murine double minute-2 (MDM2) gene. BMC Cancer 2008, 8:113. 10.1186/1471-2407-8-113, 2377274, 18433484.
-
(2008)
BMC Cancer
, vol.8
, pp. 113
-
-
Mittelstrass, K.1
Sauter, W.2
Rosenberger, A.3
Illig, T.4
Timofeeva, M.5
Klopp, N.6
Dienemann, H.7
Meese, E.8
Sybrecht, G.9
Woelke, G.10
Cebulla, M.11
Degen, M.12
-
6
-
-
38349074071
-
Genetic polymorphisms of MDM2, cumulative cigarette smoking and nonsmall cell lung cancer risk
-
10.1002/ijc.23178, 17957785
-
Liu G, Wheatley-Price P, Zhou W, Park S, Heist RS, Asomaning K, Wain JC, Lynch TJ, Su L, Christiani DC. Genetic polymorphisms of MDM2, cumulative cigarette smoking and nonsmall cell lung cancer risk. Int J Cancer 2008, 122:915-8. 10.1002/ijc.23178, 17957785.
-
(2008)
Int J Cancer
, vol.122
, pp. 915-918
-
-
Liu, G.1
Wheatley-Price, P.2
Zhou, W.3
Park, S.4
Heist, R.S.5
Asomaning, K.6
Wain, J.C.7
Lynch, T.J.8
Su, L.9
Christiani, D.C.10
-
7
-
-
33748038740
-
MDM2 SNP309 and SNP354 are not associated with lung cancer risk
-
10.1158/1055-9965.EPI-06-0217, 16896050
-
Pine SR, Mechanic LE, Bowman ED, Welsh JA, Chanock SC, Shields PG, Harris CC. MDM2 SNP309 and SNP354 are not associated with lung cancer risk. Cancer Epidemiol Biomarkers Prev 2006, 15:1559-61. 10.1158/1055-9965.EPI-06-0217, 16896050.
-
(2006)
Cancer Epidemiol Biomarkers Prev
, vol.15
, pp. 1559-1561
-
-
Pine, S.R.1
Mechanic, L.E.2
Bowman, E.D.3
Welsh, J.A.4
Chanock, S.C.5
Shields, P.G.6
Harris, C.C.7
-
8
-
-
31844433337
-
Genetic variants in the MDM2 promoter and lung cancer risk in a Chinese population
-
10.1002/ijc.21463, 16152608
-
Hu Z, Ma H, Lu D, Qian J, Zhou J, Chen Y, Xu L, Wang X, Wei Q, Shen H. Genetic variants in the MDM2 promoter and lung cancer risk in a Chinese population. Int J Cancer 2006, 118:1275-8. 10.1002/ijc.21463, 16152608.
-
(2006)
Int J Cancer
, vol.118
, pp. 1275-1278
-
-
Hu, Z.1
Ma, H.2
Lu, D.3
Qian, J.4
Zhou, J.5
Chen, Y.6
Xu, L.7
Wang, X.8
Wei, Q.9
Shen, H.10
-
9
-
-
33750297735
-
MDM2 309T>G polymorphism and risk of lung cancer in a Korean population
-
10.1016/j.lungcan.2006.06.008, 16876289
-
Park SH, Choi JE, Kim EJ, Jang JS, Han HS, Lee WK, Kang YM, Park JY. MDM2 309T>G polymorphism and risk of lung cancer in a Korean population. Lung Cancer 2006, 54:19-24. 10.1016/j.lungcan.2006.06.008, 16876289.
-
(2006)
Lung Cancer
, vol.54
, pp. 19-24
-
-
Park, S.H.1
Choi, J.E.2
Kim, E.J.3
Jang, J.S.4
Han, H.S.5
Lee, W.K.6
Kang, Y.M.7
Park, J.Y.8
-
10
-
-
29944441900
-
Genetic polymorphisms in cell cycle regulatory genes MDM2 and TP53 are associated with susceptibility to lung cancer
-
10.1002/humu.20277, 16287156
-
Zhang X, Miao X, Guo Y, Tan W, Zhou Y, Sun T, Wang Y, Lin D. Genetic polymorphisms in cell cycle regulatory genes MDM2 and TP53 are associated with susceptibility to lung cancer. Hum Mutat 2006, 27:110-7. 10.1002/humu.20277, 16287156.
-
(2006)
Hum Mutat
, vol.27
, pp. 110-117
-
-
Zhang, X.1
Miao, X.2
Guo, Y.3
Tan, W.4
Zhou, Y.5
Sun, T.6
Wang, Y.7
Lin, D.8
-
11
-
-
33744918197
-
Association of a functional polymorphism in the promoter of the MDM2 gene with risk of nonsmall cell lung cancer
-
10.1002/ijc.21872, 16496380
-
Lind H, Zienolddiny S, Ekstrøm PO, Skaug V, Haugen A. Association of a functional polymorphism in the promoter of the MDM2 gene with risk of nonsmall cell lung cancer. Int J Cancer 2006, 119:718-21. 10.1002/ijc.21872, 16496380.
-
(2006)
Int J Cancer
, vol.119
, pp. 718-721
-
-
Lind, H.1
Zienolddiny, S.2
Ekstrøm, P.O.3
Skaug, V.4
Haugen, A.5
-
12
-
-
33749546905
-
MDM2 gene promoter polymorphisms and risk of lung cancer: a case-control analysis
-
10.1093/carcin/bgl047, 16675470
-
Li G, Zhai X, Zhang Z, Chamberlain RM, Spitz MR, Wei Q. MDM2 gene promoter polymorphisms and risk of lung cancer: a case-control analysis. Carcinogenesis 2006, 27:2028-33. 10.1093/carcin/bgl047, 16675470.
-
(2006)
Carcinogenesis
, vol.27
, pp. 2028-2033
-
-
Li, G.1
Zhai, X.2
Zhang, Z.3
Chamberlain, R.M.4
Spitz, M.R.5
Wei, Q.6
-
13
-
-
36248995926
-
MDM2 SNP309 and cancer risk: a combined analysis
-
10.1093/carcin/bgm191, 17827408
-
Wilkening S, Bermejo JL, Hemminki K. MDM2 SNP309 and cancer risk: a combined analysis. Carcinogenesis 2007, 28:2262-7. 10.1093/carcin/bgm191, 17827408.
-
(2007)
Carcinogenesis
, vol.28
, pp. 2262-2267
-
-
Wilkening, S.1
Bermejo, J.L.2
Hemminki, K.3
-
14
-
-
50249125475
-
Association of p53 codon 72 polymorphism and MDM2 SNP309 with clinical outcome of advanced nonsmall cell lung cancer
-
10.1002/cncr.23668, 18618574
-
Han JY, Lee GK, Jang DH, Lee SY, Lee JS. Association of p53 codon 72 polymorphism and MDM2 SNP309 with clinical outcome of advanced nonsmall cell lung cancer. Cancer 2008, 113:799-807. 10.1002/cncr.23668, 18618574.
-
(2008)
Cancer
, vol.113
, pp. 799-807
-
-
Han, J.Y.1
Lee, G.K.2
Jang, D.H.3
Lee, S.Y.4
Lee, J.S.5
-
15
-
-
34250199746
-
MDM2 polymorphism, survival, and histology in early-stage non-small-cell lung cancer
-
10.1200/JCO.2006.08.8914, 17538168
-
Heist RS, Zhou W, Chirieac LR, Cogan-Drew T, Liu G, Su L, Neuberg D, Lynch TJ, Wain JC, Christiani DC. MDM2 polymorphism, survival, and histology in early-stage non-small-cell lung cancer. J Clin Oncol 2007, 25:2243-7. 10.1200/JCO.2006.08.8914, 17538168.
-
(2007)
J Clin Oncol
, vol.25
, pp. 2243-2247
-
-
Heist, R.S.1
Zhou, W.2
Chirieac, L.R.3
Cogan-Drew, T.4
Liu, G.5
Su, L.6
Neuberg, D.7
Lynch, T.J.8
Wain, J.C.9
Christiani, D.C.10
-
16
-
-
0023125537
-
Primary structure polymorphism at amino acid residue 72 of human p53
-
365159, 3547088
-
Matlashewski GJ, Tuck S, Pim D, Lamb P, Schneider J, Crawford LV. Primary structure polymorphism at amino acid residue 72 of human p53. Mol Cell Biol 1987, 7:961-3. 365159, 3547088.
-
(1987)
Mol Cell Biol
, vol.7
, pp. 961-963
-
-
Matlashewski, G.J.1
Tuck, S.2
Pim, D.3
Lamb, P.4
Schneider, J.5
Crawford, L.V.6
-
17
-
-
0029968463
-
Analysis of a germ line polymorphism of the p53 gene in lung cancer patients; discrete results with smoking history
-
10.1093/carcin/17.2.261, 8625447
-
Murata M, Tagawa M, Kimura M, Kimura H, Watanabe S, Saisho H. Analysis of a germ line polymorphism of the p53 gene in lung cancer patients; discrete results with smoking history. Carcinogenesis 1996, 17:261-4. 10.1093/carcin/17.2.261, 8625447.
-
(1996)
Carcinogenesis
, vol.17
, pp. 261-264
-
-
Murata, M.1
Tagawa, M.2
Kimura, M.3
Kimura, H.4
Watanabe, S.5
Saisho, H.6
-
18
-
-
0036566749
-
P53 Genotypes and Haplotypes Associated With Lung Cancer Susceptibility and Ethnicity
-
Wu X, Zhao H, Amos CI, Shete S, Makan N, Hong WK, Kadlubar FF, Spitz MR. p53 Genotypes and Haplotypes Associated With Lung Cancer Susceptibility and Ethnicity. J Natl Cancer Inst 2002, 94:681-90.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 681-690
-
-
Wu, X.1
Zhao, H.2
Amos, C.I.3
Shete, S.4
Makan, N.5
Hong, W.K.6
Kadlubar, F.F.7
Spitz, M.R.8
-
19
-
-
0038494642
-
TP53 polymorphisms and lung cancer risk: a systematic review and meta-analysis
-
10.1093/mutage/geg008, 12840112
-
Matakidou A, Eisen T, Houlston RS. TP53 polymorphisms and lung cancer risk: a systematic review and meta-analysis. Mutagenesis 2003, 18:377-85. 10.1093/mutage/geg008, 12840112.
-
(2003)
Mutagenesis
, vol.18
, pp. 377-385
-
-
Matakidou, A.1
Eisen, T.2
Houlston, R.S.3
-
20
-
-
27144545357
-
TP53 mutation, allelism and survival in non-small cell lung cancer
-
10.1093/carcin/bgi125, 15905205
-
Nelson HH, Wilkojmen M, Marsit CJ, Kelsey KT. TP53 mutation, allelism and survival in non-small cell lung cancer. Carcinogenesis 2005, 26:1770-3. 10.1093/carcin/bgi125, 15905205.
-
(2005)
Carcinogenesis
, vol.26
, pp. 1770-1773
-
-
Nelson, H.H.1
Wilkojmen, M.2
Marsit, C.J.3
Kelsey, K.T.4
-
21
-
-
0032900988
-
P53 codon 72 polymorphism in Taiwanese lung cancer patients: association with lung cancer susceptibility and prognosis
-
Wang YC, Chen CY, Chen SK, Chang YY, Lin P. p53 codon 72 polymorphism in Taiwanese lung cancer patients: association with lung cancer susceptibility and prognosis. Clin Cancer Res 1999, 5:129-34.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 129-134
-
-
Wang, Y.C.1
Chen, C.Y.2
Chen, S.K.3
Chang, Y.Y.4
Lin, P.5
-
22
-
-
33644751545
-
Increased risk of non-small cell lung cancer and frequency of somatic TP53 gene mutations in Pro72 carriers of TP53 Arg72Pro polymorphism
-
10.1016/j.lungcan.2005.12.007, 16499995
-
Szymanowska A, Jassem E, Dziadziuszko R, Borg A, Limon J, Kobierska-Gulida G, Rzyman W, Jassem J. Increased risk of non-small cell lung cancer and frequency of somatic TP53 gene mutations in Pro72 carriers of TP53 Arg72Pro polymorphism. Lung Cancer 2006, 52:9-14. 10.1016/j.lungcan.2005.12.007, 16499995.
-
(2006)
Lung Cancer
, vol.52
, pp. 9-14
-
-
Szymanowska, A.1
Jassem, E.2
Dziadziuszko, R.3
Borg, A.4
Limon, J.5
Kobierska-Gulida, G.6
Rzyman, W.7
Jassem, J.8
-
23
-
-
35448941459
-
Frequency of TP53 mutations in relation to Arg72Pro genotypes in non small cell lung cancer
-
Lind H, Ekstrom H, Ryberg PO, Skaug V, Andreassen T, Stangeland L, Haugen A, Zienolddiny S. Frequency of TP53 mutations in relation to Arg72Pro genotypes in non small cell lung cancer. Cancer Epidem Biom Prev 2007, 16:2077-81.
-
(2007)
Cancer Epidem Biom Prev
, vol.16
, pp. 2077-2081
-
-
Lind, H.1
Ekstrom, H.2
Ryberg, P.O.3
Skaug, V.4
Andreassen, T.5
Stangeland, L.6
Haugen, A.7
Zienolddiny, S.8
-
24
-
-
33947502512
-
Lung cancer in never smokers: a review
-
10.1200/JCO.2006.06.8015, 17290066
-
Subramanian J, Govindan R. Lung cancer in never smokers: a review. J Clin Oncol 2007, 25:561-70. 10.1200/JCO.2006.06.8015, 17290066.
-
(2007)
J Clin Oncol
, vol.25
, pp. 561-570
-
-
Subramanian, J.1
Govindan, R.2
-
25
-
-
34648815009
-
Lung cancer in never smokers--a different disease
-
10.1038/nrc2190, 17882278
-
Sun S, Schiller JH, Gazdar AF. Lung cancer in never smokers--a different disease. Nat Rev Cancer 2007, 7:778-90. 10.1038/nrc2190, 17882278.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 778-790
-
-
Sun, S.1
Schiller, J.H.2
Gazdar, A.F.3
-
26
-
-
41849110219
-
MDM2 SNP309 G allele increases risk but the T allele is associated with earlier onset age of sporadic breast cancers in the Chinese population
-
10.1093/carcin/bgn024, 18281248
-
Lum SS, Chua HW, Li H, Li WF, Rao N, Wei J, Shao Z, Sabapathy K. MDM2 SNP309 G allele increases risk but the T allele is associated with earlier onset age of sporadic breast cancers in the Chinese population. Carcinogenesis 2008, 29:754-61. 10.1093/carcin/bgn024, 18281248.
-
(2008)
Carcinogenesis
, vol.29
, pp. 754-761
-
-
Lum, S.S.1
Chua, H.W.2
Li, H.3
Li, W.F.4
Rao, N.5
Wei, J.6
Shao, Z.7
Sabapathy, K.8
-
27
-
-
0033737890
-
Fumes from meat cooking and lung cancer risk in Chinese women
-
Seow A, Poh WT, Teh M, Eng P, Wang YT, Tan WC, Yu MC, Lee HP. Fumes from meat cooking and lung cancer risk in Chinese women. Cancer Epidemiol Biomarkers Prev 2000, 9:1215-21.
-
(2000)
Cancer Epidemiol Biomarkers Prev
, vol.9
, pp. 1215-1221
-
-
Seow, A.1
Poh, W.T.2
Teh, M.3
Eng, P.4
Wang, Y.T.5
Tan, W.C.6
Yu, M.C.7
Lee, H.P.8
-
28
-
-
40849112781
-
MDM2 SNP309 G allele decreases risk but does not affect onset age or survival of Chinese leukaemia patients
-
10.1016/j.ejca.2008.02.007, 18313915
-
Phang BH, Linn YC, Li H, Sabapathy K. MDM2 SNP309 G allele decreases risk but does not affect onset age or survival of Chinese leukaemia patients. Eur J Cancer 2008, 44:760-6. 10.1016/j.ejca.2008.02.007, 18313915.
-
(2008)
Eur J Cancer
, vol.44
, pp. 760-766
-
-
Phang, B.H.1
Linn, Y.C.2
Li, H.3
Sabapathy, K.4
-
29
-
-
0041630956
-
Estrogen receptor-dependent proteasomal degradation of the glucocorticoid receptor is coupled to an increase in mdm2 protein expression
-
10.1128/MCB.23.16.5867-5881.2003, 166332, 12897156
-
Kinyamu HK, Archer TK. Estrogen receptor-dependent proteasomal degradation of the glucocorticoid receptor is coupled to an increase in mdm2 protein expression. Mol Cell Biol 2003, 23:5867-81. 10.1128/MCB.23.16.5867-5881.2003, 166332, 12897156.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5867-5881
-
-
Kinyamu, H.K.1
Archer, T.K.2
-
30
-
-
33744899069
-
MDM2 SNP309 accelerates tumor formation in a gender-specific and hormone-dependent manner
-
10.1158/0008-5472.CAN-06-0180, 16707433
-
Bond GL, Hirshfield KM, Kirchhoff T, Alexe G, Bond EE, Robins H, Bartel F, Taubert H, Wuerl P, Hait W, Toppmeyer D, Offit K, et al. MDM2 SNP309 accelerates tumor formation in a gender-specific and hormone-dependent manner. Cancer Res 2006, 66:5104-10. 10.1158/0008-5472.CAN-06-0180, 16707433.
-
(2006)
Cancer Res
, vol.66
, pp. 5104-5110
-
-
Bond, G.L.1
Hirshfield, K.M.2
Kirchhoff, T.3
Alexe, G.4
Bond, E.E.5
Robins, H.6
Bartel, F.7
Taubert, H.8
Wuerl, P.9
Hait, W.10
Toppmeyer, D.11
Offit, K.12
-
31
-
-
34347262483
-
Differential regulation of estrogen receptor alpha turnover and transactivation by Mdm2 and stress-inducing agents
-
10.1158/0008-5472.CAN-07-0967, 17545634
-
Duong V, Boulle N, Daujat S, Chauvet J, Bonnet S, Neel H, Cavailles V. Differential regulation of estrogen receptor alpha turnover and transactivation by Mdm2 and stress-inducing agents. Cancer Res 2007, 67:5513-21. 10.1158/0008-5472.CAN-07-0967, 17545634.
-
(2007)
Cancer Res
, vol.67
, pp. 5513-5521
-
-
Duong, V.1
Boulle, N.2
Daujat, S.3
Chauvet, J.4
Bonnet, S.5
Neel, H.6
Cavailles, V.7
-
32
-
-
0034811996
-
Expression, function, and clinical implications of the estrogen receptor beta in human lung cancers
-
10.1006/bbrc.2001.5158, 11444848
-
Omoto Y, Kobayashi Y, Nishida K, Tsuchiya E, Eguchi H, Nakagawa K, Ishikawa Y, Yamori T, Iwase H, Fujii Y, Warner M, Gustafsson JA, et al. Expression, function, and clinical implications of the estrogen receptor beta in human lung cancers. Biochem Biophys Res Commun 2001, 285:340-7. 10.1006/bbrc.2001.5158, 11444848.
-
(2001)
Biochem Biophys Res Commun
, vol.285
, pp. 340-347
-
-
Omoto, Y.1
Kobayashi, Y.2
Nishida, K.3
Tsuchiya, E.4
Eguchi, H.5
Nakagawa, K.6
Ishikawa, Y.7
Yamori, T.8
Iwase, H.9
Fujii, Y.10
Warner, M.11
Gustafsson, J.A.12
-
33
-
-
0036532167
-
Human non-small cell lung tumors and cells derived from normal lung express both estrogen receptor alpha and beta and show biological responses to estrogen
-
Stabile LP, Davis AL, Gubish CT, Hopkins TM, Luketich JD, Christie N, Finkelstein S, Siegfried JM. Human non-small cell lung tumors and cells derived from normal lung express both estrogen receptor alpha and beta and show biological responses to estrogen. Cancer Res 2002, 62:2141-50.
-
(2002)
Cancer Res
, vol.62
, pp. 2141-2150
-
-
Stabile, L.P.1
Davis, A.L.2
Gubish, C.T.3
Hopkins, T.M.4
Luketich, J.D.5
Christie, N.6
Finkelstein, S.7
Siegfried, J.M.8
|