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Volumn 1, Issue 6, 2010, Pages 551-554

Beyond ergosterol: Linking ph to antifungal mechanisms

Author keywords

Candida albicans; Ergosterol; Ph homeostasis; V atpase; Vacuole; Yeast

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ALLYLAMINE DERIVATIVE; ANTIFUNGAL AGENT; ERGOSTEROL; MORPHOLINE DERIVATIVE; POLYENE; PYRROLE DERIVATIVE; SPHINGOLIPID;

EID: 79251472093     PISSN: 21505594     EISSN: 21505608     Source Type: Journal    
DOI: 10.4161/viru.1.6.13802     Document Type: Article
Times cited : (50)

References (36)
  • 1
    • 0025265898 scopus 로고
    • Interaction of azole antifungal antibiotics with cytochrome P-450-dependent 14 alphasterol demethylase purified from Candida albicans
    • Hitchcock CA, Dickinson K, Brown SB, Evans EG, Adams DJ. Interaction of azole antifungal antibiotics with cytochrome P-450-dependent 14 alphasterol demethylase purified from Candida albicans. Biochem J 1990; 266:475-80.
    • (1990) Biochem J , vol.266 , pp. 475-480
    • Hitchcock, C.A.1    Dickinson, K.2    Brown, S.B.3    Evans, E.G.4    Adams, D.J.5
  • 2
    • 0021800106 scopus 로고
    • Effect of allylamine antimycotic agents on fungal sterol biosynthesis measured by sterol side-chain methylation
    • Ryder NS. Effect of allylamine antimycotic agents on fungal sterol biosynthesis measured by sterol side-chain methylation. J Gen Microbiol 1985; 131:1595-602.
    • (1985) J Gen Microbiol , vol.131 , pp. 1595-1602
    • Ryder, N.S.1
  • 3
    • 0025325362 scopus 로고
    • In vivo effects of fenpropimorph on the yeast Saccharomyces cerevisiae and determination of the molecular basis of the antifungal property
    • Marcireau C, Guilloton M, Karst F. In vivo effects of fenpropimorph on the yeast Saccharomyces cerevisiae and determination of the molecular basis of the antifungal property. Antimicrob Agents Chemother 1990; 34:989-93.
    • (1990) Antimicrob Agents Chemother , vol.34 , pp. 989-993
    • Marcireau, C.1    Guilloton, M.2    Karst, F.3
  • 4
    • 77954685203 scopus 로고    scopus 로고
    • Requirement for ergosterol in V-ATPase function underlies antifungal activity of azole drugs
    • Zhang YQ, Gamarra S, Garcia-Effron G, Park S, Perlin DS, Rao R. Requirement for ergosterol in V-ATPase function underlies antifungal activity of azole drugs. PLoS Pathog 2010; 6:e1000939.
    • (2010) PLoS Pathog , vol.6
    • Zhang, Y.Q.1    Gamarra, S.2    Garcia-Effron, G.3    Park, S.4    Perlin, D.S.5    Rao, R.6
  • 5
    • 40849120821 scopus 로고    scopus 로고
    • Ergosterol promotes pheromone signaling and plasma membrane fusion in mating yeast
    • Jin H, McCaffery JM, Grote E. Ergosterol promotes pheromone signaling and plasma membrane fusion in mating yeast. J Cell Biol 2008; 180:813-26.
    • (2008) J Cell Biol , vol.180 , pp. 813-826
    • Jin, H.1    McCaffery, J.M.2    Grote, E.3
  • 6
    • 0034724182 scopus 로고    scopus 로고
    • Lipid rafts function in biosynthetic delivery of proteins to the cell surface in yeast
    • Bagnat M, Keranen S, Shevchenko A, Simons K. Lipid rafts function in biosynthetic delivery of proteins to the cell surface in yeast. Proc Natl Acad Sci USA 2000; 97:3254-9.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 3254-3259
    • Bagnat, M.1    Keranen, S.2    Shevchenko, A.3    Simons, K.4
  • 7
    • 0038491550 scopus 로고    scopus 로고
    • Ergosterol is required for targeting of tryptophan permease to the yeast plasma membrane
    • Umebayashi K, Nakano A. Ergosterol is required for targeting of tryptophan permease to the yeast plasma membrane. J Cell Biol 2003; 161:1117-31.
    • (2003) J Cell Biol , vol.161 , pp. 1117-1131
    • Umebayashi, K.1    Nakano, A.2
  • 8
    • 29144534564 scopus 로고    scopus 로고
    • A genomewide visual screen reveals a role for sphingolipids and ergosterol in cell surface delivery in yeast
    • Proszynski TJ, Klemm RW, Gravert M, Hsu PP, Gloor Y, Wagner J, et al. A genomewide visual screen reveals a role for sphingolipids and ergosterol in cell surface delivery in yeast. Proc Natl Acad Sci USA 2005; 102:17981-6.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 17981-17986
    • Proszynski, T.J.1    Klemm, R.W.2    Gravert, M.3    Hsu, P.P.4    Gloor, Y.5    Wagner, J.6
  • 10
    • 0035423116 scopus 로고    scopus 로고
    • Ergosterol is required for the Sec18/ATP-dependent priming step of homotypic vacuole fusion
    • Kato M, Wickner W. Ergosterol is required for the Sec18/ATP-dependent priming step of homotypic vacuole fusion. EMBO J 2001; 20:4035-40.
    • (2001) EMBO J , vol.20 , pp. 4035-4040
    • Kato, M.1    Wickner, W.2
  • 11
    • 27644467457 scopus 로고    scopus 로고
    • Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae
    • Altmann K, Westermann B. Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae. Mol Biol Cell 2005; 16:5410-7.
    • (2005) Mol Biol Cell , vol.16 , pp. 5410-5417
    • Altmann, K.1    Westermann, B.2
  • 12
    • 0031692484 scopus 로고    scopus 로고
    • A calcium-dependent ergosterol mutant of Saccharomyces cerevisiae
    • Crowley JH, Tove S, Parks LW. A calcium-dependent ergosterol mutant of Saccharomyces cerevisiae. Curr Genet 1998; 34:93-9.
    • (1998) Curr Genet , vol.34 , pp. 93-99
    • Crowley, J.H.1    Tove, S.2    Parks, L.W.3
  • 13
    • 0027993524 scopus 로고
    • Mutations in LIS1 (ERG6) gene confer increased sodium and lithium uptake in Saccharomyces cerevisiae
    • Welihinda AA, Beavis AD, Trumbly RJ. Mutations in LIS1 (ERG6) gene confer increased sodium and lithium uptake in Saccharomyces cerevisiae. Biochim Biophys Acta 1994; 1193:107-17.
    • (1994) Biochim Biophys Acta , vol.1193 , pp. 107-117
    • Welihinda, A.A.1    Beavis, A.D.2    Trumbly, R.J.3
  • 14
    • 0041706252 scopus 로고    scopus 로고
    • Antifungal activity of amiodarone is mediated by disruption of calcium homeostasis
    • Gupta SS, Ton VK, Beaudry V, Rulli S, Cunningham K, Rao R. Antifungal activity of amiodarone is mediated by disruption of calcium homeostasis. J Biol Chem 2003; 278:28831-9.
    • (2003) J Biol Chem , vol.278 , pp. 28831-28839
    • Gupta, S.S.1    Ton, V.K.2    Beaudry, V.3    Rulli, S.4    Cunningham, K.5    Rao, R.6
  • 15
    • 50549104079 scopus 로고    scopus 로고
    • Regulation of the V-ATPase along the endocytic pathway occurs through reversible subunit association and membrane localization
    • Lafourcade C, Sobo K, Kieffer-Jaquinod S, Garin J, van der Goot FG. Regulation of the V-ATPase along the endocytic pathway occurs through reversible subunit association and membrane localization. PLoS One 2008; 3:e2758.
    • (2008) PLoS One , vol.3
    • Lafourcade, C.1    Sobo, K.2    Kieffer-Jaquinod, S.3    Garin, J.4    van der Goot, F.G.5
  • 16
    • 2542446264 scopus 로고    scopus 로고
    • Identification of VATPase as a major component in the raft fraction prepared from the synaptic plasma membrane and the synaptic vesicle of rat brain
    • Yoshinaka K, Kumanogoh H, Nakamura S, Maekawa S. Identification of VATPase as a major component in the raft fraction prepared from the synaptic plasma membrane and the synaptic vesicle of rat brain. Neurosci Lett 2004; 363:168-72.
    • (2004) Neurosci Lett , vol.363 , pp. 168-172
    • Yoshinaka, K.1    Kumanogoh, H.2    Nakamura, S.3    Maekawa, S.4
  • 17
    • 77956464497 scopus 로고    scopus 로고
    • Proteomic analysis of osteoclast lipid rafts: The role of the integrity of lipid rafts on V-ATPase activity in osteoclasts
    • Ryu J, Kim H, Chang EJ, Kim HJ, Lee Y, Kim HH. Proteomic analysis of osteoclast lipid rafts: the role of the integrity of lipid rafts on V-ATPase activity in osteoclasts. J Bone Miner Metab 2010; 28:410-7.
    • (2010) J Bone Miner Metab , vol.28 , pp. 410-417
    • Ryu, J.1    Kim, H.2    Chang, E.J.3    Kim, H.J.4    Lee, Y.5    Kim, H.H.6
  • 18
    • 11844260070 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase-mediated effects of glucose on vacuolar H+-ATPase assembly, translocation, and acidification of intracellular compartments in renal epithelial cells
    • Sautin YY, Lu M, Gaugler A, Zhang L, Gluck SL. Phosphatidylinositol 3-kinase-mediated effects of glucose on vacuolar H+-ATPase assembly, translocation, and acidification of intracellular compartments in renal epithelial cells. Mol Cell Biol 2005; 25:575-89.
    • (2005) Mol Cell Biol , vol.25 , pp. 575-589
    • Sautin, Y.Y.1    Lu, M.2    Gaugler, A.3    Zhang, L.4    Gluck, S.L.5
  • 19
    • 59449104347 scopus 로고    scopus 로고
    • Cardiolipin mediates crosstalk between mitochondria and the vacuole
    • Chen S, Tarsio M, Kane PM, Greenberg ML. Cardiolipin mediates crosstalk between mitochondria and the vacuole. Mol Biol Cell 2008; 19:5047-58.
    • (2008) Mol Biol Cell , vol.19 , pp. 5047-5058
    • Chen, S.1    Tarsio, M.2    Kane, P.M.3    Greenberg, M.L.4
  • 20
    • 0041706233 scopus 로고    scopus 로고
    • Sphingolipid requirement for generation of a functional v1 component of the vacuolar ATPase
    • Chung JH, Lester RL, Dickson RC. Sphingolipid requirement for generation of a functional v1 component of the vacuolar ATPase. J Biol Chem 2003; 278:28872-81.
    • (2003) J Biol Chem , vol.278 , pp. 28872-28881
    • Chung, J.H.1    Lester, R.L.2    Dickson, R.C.3
  • 21
    • 33645119556 scopus 로고    scopus 로고
    • The where, when, and how of organelle acidification by the yeast vacuolar H+-ATPase
    • Kane PM. The where, when, and how of organelle acidification by the yeast vacuolar H+-ATPase. Microbiol Mol Biol Rev 2006; 70:177-91.
    • (2006) Microbiol Mol Biol Rev , vol.70 , pp. 177-191
    • Kane, P.M.1
  • 22
    • 0036481562 scopus 로고    scopus 로고
    • The vacuolar (H+)-ATPases-- nature's most versatile proton pumps
    • Nishi T, Forgac M. The vacuolar (H+)-ATPases-- nature's most versatile proton pumps. Nat Rev Mol Cell Biol 2002; 3:94-103.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 94-103
    • Nishi, T.1    Forgac, M.2
  • 24
    • 58149136353 scopus 로고    scopus 로고
    • Candida albicans cell surface superoxide dismutases degrade host-derived reactive oxygen species to escape innate immune surveillance
    • Frohner IE, Bourgeois C, Yatsyk K, Majer O, Kuchler K. Candida albicans cell surface superoxide dismutases degrade host-derived reactive oxygen species to escape innate immune surveillance. Mol Microbiol 2009; 71:240-52.
    • (2009) Mol Microbiol , vol.71 , pp. 240-252
    • Frohner, I.E.1    Bourgeois, C.2    Yatsyk, K.3    Majer, O.4    Kuchler, K.5
  • 25
    • 55949104672 scopus 로고    scopus 로고
    • Candida albicans-secreted lipase induces injury and steatosis in immune and parenchymal cells
    • Paraje MG, Correa SG, Renna MS, Theumer M, Sotomayor CE. Candida albicans-secreted lipase induces injury and steatosis in immune and parenchymal cells. Can J Microbiol 2008; 54:647-59.
    • (2008) Can J Microbiol , vol.54 , pp. 647-659
    • Paraje, M.G.1    Correa, S.G.2    Renna, M.S.3    Theumer, M.4    Sotomayor, C.E.5
  • 26
    • 19044365896 scopus 로고    scopus 로고
    • The putative vacuolar ATPase subunit Vma7p of Candida albicans is involved in vacuole acidification, hyphal development and virulence
    • Poltermann S, Nguyen M, Gunther J, Wendland J, Hartl A, Kunkel W, et al. The putative vacuolar ATPase subunit Vma7p of Candida albicans is involved in vacuole acidification, hyphal development and virulence. Microbiology 2005; 151:1645-55.
    • (2005) Microbiology , vol.151 , pp. 1645-1655
    • Poltermann, S.1    Nguyen, M.2    Gunther, J.3    Wendland, J.4    Hartl, A.5    Kunkel, W.6
  • 29
    • 0032942954 scopus 로고    scopus 로고
    • Effects of azole antifungal drugs on the transition from yeast cells to hyphae in susceptible and resistant isolates of the pathogenic yeast Candida albicans
    • Ha KC, White TC. Effects of azole antifungal drugs on the transition from yeast cells to hyphae in susceptible and resistant isolates of the pathogenic yeast Candida albicans. Antimicrob Agents Chemother 1999; 43:763-8.
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 763-768
    • Ha, K.C.1    White, T.C.2
  • 30
    • 58849115883 scopus 로고    scopus 로고
    • Trimorphic stepping stones pave the way to fungal virulence
    • Bastidas RJ, Heitman J. Trimorphic stepping stones pave the way to fungal virulence. Proc Natl Acad Sci USA 2009; 106:351-2.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 351-352
    • Bastidas, R.J.1    Heitman, J.2
  • 31
    • 77649229368 scopus 로고    scopus 로고
    • Cellular interactions of Candida albicans with human oral epithelial cells and enterocytes
    • Dalle F, Wachtler B, L'Ollivier C, Holland G, Bannert N, Wilson D, et al. Cellular interactions of Candida albicans with human oral epithelial cells and enterocytes. Cell Microbiol 2010; 12:248-71.
    • (2010) Cell Microbiol , vol.12 , pp. 248-271
    • Dalle, F.1    Wachtler, B.2    L'ollivier, C.3    Holland, G.4    Bannert, N.5    Wilson, D.6
  • 33
    • 59149090186 scopus 로고    scopus 로고
    • Membrane hyperpolarization drives cation influx and fungicidal activity of amiodarone
    • Maresova L, Muend S, Zhang YQ, Sychrova H, Rao R. Membrane hyperpolarization drives cation influx and fungicidal activity of amiodarone. J Biol Chem 2009; 284:2795-802.
    • (2009) J Biol Chem , vol.284 , pp. 2795-2802
    • Maresova, L.1    Muend, S.2    Zhang, Y.Q.3    Sychrova, H.4    Rao, R.5
  • 34
    • 42549083374 scopus 로고    scopus 로고
    • Fungicidal activity of amiodarone is tightly coupled to calcium influx
    • Muend S, Rao R. Fungicidal activity of amiodarone is tightly coupled to calcium influx. FEMS Yeast Res 2008; 8:425-31.
    • (2008) FEMS Yeast Res , vol.8 , pp. 425-431
    • Muend, S.1    Rao, R.2
  • 36
    • 42149168443 scopus 로고    scopus 로고
    • Synergistic activity of azoles with amiodarone against clinically resistant Candida albicans tested by chequerboard and timekill methods
    • Guo Q, Sun S, Yu J, Li Y, Cao L. Synergistic activity of azoles with amiodarone against clinically resistant Candida albicans tested by chequerboard and timekill methods. J Med Microbiol 2008; 57:457-62.
    • (2008) J Med Microbiol , vol.57 , pp. 457-462
    • Guo, Q.1    Sun, S.2    Yu, J.3    Li, Y.4    Cao, L.5


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