Crystal structure of SUMO-modified proliferating cell nuclear antigen

Journal of Molecular Biology

Volumn 406, Issue 1, 2011, Pages 9-17

  Freudenthal, Bret D ^a   Brogie, John E ^a   Gakhar, Lokesh ^a   Kondratick, Christine M ^a   Washington, M Todd ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

DNA recombination; DNA repair; DNA replication; protein DNA interactions; translesion synthesis

Indexed keywords

CYCLINE; DNA POLYMERASE; SUMO PROTEIN; UBIQUITIN;

ARTICLE; CELL VIABILITY; CRYSTAL STRUCTURE; DNA REPLICATION; ENZYME ACTIVITY; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; X RAY ANALYSIS;

EUKARYOTA;

EID: 79151484195     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2010.12.015     Document Type: Article

References (42)

1. Krishna T.S.R., Kong X.P., Gary S., Burgers P.M., and Kuriyan J. Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA Cell 79 1994 1233 1243
2. Mossi R., and Hubscher U. Clamping down on clamps and clamp loaders-the eukaryotic replication factor C Eur. J. Biochem. 254 1998 209 216
3. Majka J., and Burgers P.M.J. The PCNA-RFC families of DNA clamps and clamp loaders Prog. Nucleic Acid Res. Mol. Biol. 78 2004 227 260
4. Warbrick E. PCNA binding through a conserved motif BioEssays 20 1998 195 199
5. Warbrick E. The puzzle of PCNA's many partners BioEssays 22 2000 997 1006
6. Hingorani M.M., and O'Donnell M. Sliding clamps: a (tail)ored fit Curr. Biol. 10 2000 R25 R29
7. Maga G., and Hubscher U. Proliferating cell nuclear antigen (PCNA): a dancer with many partners J. Cell Sci. 116 2003 3051 3060
8. Moldovan G.L., Pfander B., and Jentsch S. PCNA, the maestro of the replication fork Cell 129 2007 665 679
9. Tsurimoto T. PCNA binding proteins Front. Biosci. 4 1999 d849 858
10. Ulrich H.D. Regulating post-translational modifications of the eukaryotic replication clamp PCNA DNA Repair 8 2009 461 469
11. Ulrich H.D., Vogel S., and Davies A.A. SUMO keeps a check on recombination during DNA replication Cell Cycle 4 2005 1699 1702
12. Ulrich H.D., and Walden H. Ubiquitin signalling in DNA replication and repair Nat. Rev., Mol. Cell Biol. 11 2010 479 489
13. Watts F.Z. Sumoylation of PCNA: wrestling with recombination at stalled replication forks DNA Repair 5 2006 399 403
14. Bergink S., and Jentsch S. Principles of ubiquitin and SUMO modifications in DNA repair Nature 458 2009 461 467
15. Stelter P., and Ulrich H.D. Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation Nature 425 2003 188 191
16. Hoege C., Pfander B., Moldovan G.L., Pyrowolakis G., and Jentsch S. RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO Nature 419 2002 135 141
17. Bienko M., Green C.M., Crosetto N., Rudolf F., Zapart G., and Coull B. Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis Science 310 2005 1821 1824
18. Kannouche P.L., Wing J., and Lehmann A.R. Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage Mol. Cell 14 2004 491 500
19. Broomfield S., Chow B.L., and Xiao W. MMS2, encoding a ubiquitin-conjugating-enzyme-like protein, is a member of the yeast error-free postreplication repair pathway Proc. Natl Acad. Sci. USA 95 1998 5678 5683
20. Hofmann R.M., and Pickart C.M. Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair Cell 96 1999 645 653
21. Ulrich H.D., and Jentsch S. Two RING finger proteins mediate cooperation between ubiquitin-conjugating enzymes in DNA repair EMBO J. 19 2000 3388 3397
22. Pfander B., Moldovan G.L., Sacher M., Hoege C., and Jentsch S. SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase Nature 436 2005 428 433
23. Papouli E., Chen S.H., Davies A.A., Huttner D., Krejci L., Sung P., and Ulrich H.D. Crosstalk between SUMO and ubiquitin on PCNA is mediated by recruitment of the helicase Srs2p Mol. Cell 19 2005 123 133
24. Krejci L., Macris M., Li Y., Van Komen S., Villemain J., and Ellenberger T. Role of ATP hydrolysis in the antirecombinase function of Saccharomyces cerevisiae Srs2 protein J. Biol. Chem. 279 2004 23193 23199
25. Veaute X., Jeusset J., Soustelle C., Kowalczykowski S.C., Le Cam E., and Fabre F. The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments Nature 423 2003 309 312
26. Chen J.J., Ai Y.X., Wang J.L., Haracska L., and Zhuang Z.H. Chemically ubiquitylated PCNA as a probe for eukaryotic translesion DNA synthesis Nat. Chem. Biol. 6 2010 270 272
27. Carlile C.M., Pickart C.M., Matunis M.J., and Cohen R.E. Synthesis of free and proliferating cell nuclear antigen-bound polyubiquitin chains by the RING E3 ubiquitin ligase Rad5 J. Biol. Chem. 284 2009 29326 29334
28. Freudenthal B.D., Gakhar L., Ramaswamy S., and Washington M.T. Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange Nat. Struct. Mol. Biol. 17 2010 479 484
29. Freudenthal B.D., Ramaswamy S., Hingorani M.M., and Washington M.T. Structure of a mutant form of proliferating cell nuclear antigen that blocks translesion DNA synthesis Biochemistry 47 2008 13354 13361
30. Dieckman L.M., Johnson R.E., Prakash S., and Washington M.T. Pre-steady state kinetic studies of the fidelity of nucleotide incorporation by yeast DNA polymerase delta Biochemistry 49 2010 7344 7350
31. Garg P., Stith C.M., Majka J., and Burgers P.M.J. Proliferating cell nuclear antigen promotes translesion synthesis by DNA polymerase zeta J. Biol. Chem. 280 2005 23446 23450
32. Pflugrath J.W. The finer things in X-ray diffraction data collection Acta Crystallogr., Sect. D: Biol. Crystallogr. 55 1999 1718 1725
33. Read R.J. Pushing the boundaries of molecular replacement with maximum likelihood Acta Crystallogr., Sect. D: Biol. Crystallogr. 57 2001 1373 1382
34. Prudden J., Perry J.J.P., Arvai A.S., Tainer J.A., and Boddy M.N. Molecular mimicry of SUMO promotes DNA repair Nat. Struct. Mol. Biol. 16 2009 509 516
35. Adams P.D., Grosse-Kunstleve R.W., Hung L.W., Ioerger T.R., McCoy A.J., and Moriarty N.W. PHENIX: building new software for automated crystallographic structure determination Acta Crystallogr., Sect. D: Biol. Crystallogr. 58 2002 1948 1954
36. Bailey S. The CCP4 suite-programs for protein crystallography Acta Crystallogr., Sect. D: Biol. Crystallogr. 50 1994 760 763
37. Emsley P., and Cowtan K. Coot: model-building tools for molecular graphics Acta Crystallogr., Sect. D: Biol. Crystallogr. 60 2004 2126 2132
38. Yunus A.A., and Lima C.D. Structure of the Siz/PIAS SUMO E3 ligase Siz1 and determinants required for SUMO modification of PCNA Mol. Cell 35 2009 669 682
39. Zhang H.S., Gibbs P.E.M., and Lawrence C.W. The Saccharomyces cerevisiae rev6-1 mutation, which inhibits both the lesion bypass and the recombination mode of DNA damage tolerance, is an allele of POL30, encoding proliferating cell nuclear antigen Genetics 173 2006 1983 1989
40. Indiani C., McInerney P., Georgescu R., Goodman M.F., and O'Donnell M. A sliding-clamp toolbelt binds high- and low-fidelity DNA polymerases simultaneously Mol. Cell 19 2005 805 815
41. Sutton M.D. Coordinating DNA polymerase traffic during high and low fidelity synthesis Biochim. Biophys. Acta 1804 2010 1167 1179
42. Zhuang Z.H., and Ai Y.X. Processivity factor of DNA polymerase and its expanding role in normal and translesion DNA synthesis Biochim. Biophys. Acta 1804 2010 1081 1093