Structure of a mutant form of proliferating cell nuclear antigen that blocks translesion DNA synthesis

Biochemistry

Volumn 47, Issue 50, 2008, Pages 13354-13361

  Freudenthal, Bret D ^a   Ramaswamy, S ^a   Hingorani, Manju M ^b   Washington, M Todd ^a  

^a UNIVERSITY OF IOWA   (United States)

^b WESLEYAN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; AMINO ACIDS; ANTIGENS; CRYSTAL ATOMIC STRUCTURE; DNA; FUNCTIONAL POLYMERS; GENES; NUCLEIC ACIDS; ORGANIC ACIDS;

ABASIC SITES; AMINO ACID RESIDUES; DNA LESIONS; DNA POLYMERASES; DNA REPLICATIONS; DNA SYNTHESIS; DO-MAINS; GENETIC STUDIES; HOMOTRIMERIC PROTEINS; KINETIC STUDIES; MUTANT PROTEINS; PROLIFERATING CELL NUCLEAR ANTIGENS; PROTEIN BACKBONES; SLIDING CLAMPS; STEADY STATES; STRUCTURAL CHANGES; SUBUNIT INTERFACES; TRANSLESION; TRANSLESION SYNTHESES; TYPE STRUCTURES; X-RAY CRYSTAL STRUCTURES;

CRYSTAL STRUCTURE;

CELL NUCLEUS ANTIGEN; DNA POLYMERASE; GLYCINE; SERINE;

ALLELE; AMINO ACID SUBSTITUTION; ANTIGEN FUNCTION; ANTIGEN STRUCTURE; ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DNA REPLICATION; DNA SYNTHESIS; DNA SYNTHESIS INHIBITION; ENZYME SUBUNIT; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; STEADY STATE; STRUCTURE ANALYSIS; WILD TYPE; X RAY ANALYSIS;

CRYSTALLOGRAPHY, X-RAY; DNA DAMAGE; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; MUTATION; NUCLEIC ACID SYNTHESIS INHIBITORS; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY;

EID: 57649128297     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi8017762     Document Type: Article

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