Synthesis and anti-inflammatory evaluation of some new acyl-hydrazones bearing 2-aryl-thiazole

European Journal of Medicinal Chemistry

Volumn 46, Issue 2, 2011, Pages 526-534

  Moldovan, Cristina Mariana ^a   Oniga, Ovidiu ^a   Pârvu, Alina ^a   Tiperciuc, Brînduşa ^a   Verite, Philippe ^b   Pîrnǎu, Adrian ^c   Crişan, Ovidiu ^a   Bojiţǎ, Marius ^a   Pop, Raluca ^d  

^a IULIU HATIEGANU UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^b University of Medicine and Pharmacy   (France)

^c NATIONAL INSTITUTE FOR RESEARCH AND DEVELOPMENT OF ISOTOPIC AND MOLECULAR TECHNOLOGIES   (Romania)

^d National Institute for Research and Development for Electrochemistry and Condensed Matter   (Romania)

Author keywords

2 Aryl thiazole; Acyl hydrazone; Anti inflammatory activity

Indexed keywords

(2 4 TOLYL THIAZOL 4 YL)ACETIC ACID [3 (2 PHENYL THIAZOL 4 YLMETHOXY)BENZYLIDENE]HYDRAZIDE; (2 4 TOLYL THIAZOL 4 YL)ACETIC ACID [4 (2 PHENYL THIAZOL 4 YLMETHOXY)BENZYLIDENE]HYDRAZIDE; (2 4 TOLYL THIAZOL 4 YL)ACETIC ACID [4 [2 (4 BROMO PHENYL)THIAZOL 4 YLMETHOXY]BENZYLIDENE]HYDRAZIDE; (2 4 TOLYL THIAZOL 4 YL)ACETIC ACID [4 [2 (4 METHYL 2 PHENYLTHIAZOL 5 YL) 2 OXO ETHOXY]BENZYLIDENE]HYDRAZIDE; (2 4 TOLYL THIAZOL 4 YL)ACETIC ACID[2 [2 (4 BROMO PHENYL)THIAZOL 4 YLMETHOXY]BENZYLIDENE]HYDRAZIDE; (4 OXO 2 PHENYL 4H CHROMEN 7 YLOXY)ACETIC ACID[3 (2 PHENYL THIAZOL 4 YLMETHOXY)BENZYLIDENE]HYDRAZIDE; (4 OXO 2 PHENYL 4H CHROMEN 7 YLOXY)ACETIC ACID[3 [2 (4 BROMO PHENYL)THIAZOL 4 YLMETHOXY]BENZYLIDENE]HYDRAZIDE; (4 OXO 2 PHENYL 4H CHROMEN 7 YLOXY)ACETIC ACID[4 (2 PHENYL THIAZOL 4 YLMETHOXY)BENZYLIDENE]HYDRAZIDE; [2 (3 TRIFLUOROMETHYL PHENYL) THIAZOL 4 YL]ACETIC ACID [4 [2 (4 BROMO PHENYL)THIAZOL 4 YLMETHOXY]BENZYLIDENE]HYDRAZIDE; [2 (3 TRIFLUOROMETHYL PHENYL)THIAZOL 4 YL]ACETIC ACID [4 (2 PHENYL THIAZOL 4 YLMETHOXY)BENZYLIDENE]HYDRAZIDE; [2 (3 TRIFLUOROMETHYL PHENYL)THIAZOL 4 YL]ACETIC ACID [4 [2 (4 METHYL 2 PHENYL THIAZOL 5 YL) 2 OXO ETHOXY]BENZYLIDENE]HYDRAZIDE; [2 (3 TRIFLUOROMETHYL PHENYL)THIAZOL 4 YL]ACETIC ACID[2 [2 (4 BROMO PHENYL)THIAZOL 4 YLMETHOXY]BENZYLIDENE]HYDRAZIDE; [2 (3 TRIFLUOROMETHYL PHENYL)THIAZOL 4 YL]ACETIC ACID[3 (2 PHENYL THIAZOL 4 YLMETHOXY)BENZYLIDENE]HYDRAZIDE; [2 (3 TRIFLUOROMETHYL PHENYL)THIAZOL 4 YL]ACETIC ACID[3 [2 (4 BROMO PHENYL)THIAZOL 4 YLMETHOXY]BENZYLIDENE]HYDRAZIDE; ANTIINFLAMMATORY AGENT; BENZALDEHYDE DERIVATIVE; HYDRAZIDE DERIVATIVE; HYDRAZONE DERIVATIVE; MELOXICAM; NITRIC OXIDE; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BONE MARROW; CELL ACTIVITY; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; IN VIVO STUDY; INFLAMMATION; INFRARED SPECTROSCOPY; LEUKOCYTE COUNT; MALE; MASS SPECTROMETRY; NEUTROPHIL COUNT; NONHUMAN; PHAGOCYTE; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BONE MARROW; CYTOKINES; HYDRAZONES; INFLAMMATION; LEUKOCYTE COUNT; LEUKOCYTES; LEUKOCYTOSIS; MOLECULAR STRUCTURE; NEUTROPHILS; RATS; STEREOISOMERISM; THIAZOLES;

EID: 79151483364     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.11.032     Document Type: Article

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