-
1
-
-
0029948565
-
Epidemiology of gastric cancer
-
Neugut,A.I. et al. (1996) Epidemiology of gastric cancer. Semin. Oncol., 23, 281-291.
-
(1996)
Semin. Oncol
, vol.23
, pp. 281-291
-
-
Neugut, A.I.1
-
2
-
-
0025215205
-
Infrequent point mutations of ras oncogenes in gastric cancers
-
Nanus,D.M. et al. (1990) Infrequent point mutations of ras oncogenes in gastric cancers. Gastroenterology, 98, 955-960.
-
(1990)
Gastroenterology
, vol.98
, pp. 955-960
-
-
Nanus, D.M.1
-
3
-
-
0028169368
-
p53 mutations and microsatellite instability in sporadic gastric cancer: When guardians fail
-
Strickler,J.G. et al. (1994) p53 mutations and microsatellite instability in sporadic gastric cancer: When guardians fail. Cancer Res., 54, 4750-4755.
-
(1994)
Cancer Res
, vol.54
, pp. 4750-4755
-
-
Strickler, J.G.1
-
4
-
-
18444375277
-
DNA methylation and histone deacetylation associated with silencing DAP kinase gene expression in colorectal and gastric cancers
-
Satoh,A. et al. (2002) DNA methylation and histone deacetylation associated with silencing DAP kinase gene expression in colorectal and gastric cancers. Br. J. Cancer, 86, 1817-1823.
-
(2002)
Br. J. Cancer
, vol.86
, pp. 1817-1823
-
-
Satoh, A.1
-
5
-
-
9144239265
-
Epigenetic inactivation of CHFR and sensitivity to microtubule inhibitors in gastric cancer
-
Satoh,A. et al. (2003) Epigenetic inactivation of CHFR and sensitivity to microtubule inhibitors in gastric cancer. Cancer Res. 63, 8606-8613.
-
(2003)
Cancer Res
, vol.63
, pp. 8606-8613
-
-
Satoh, A.1
-
6
-
-
0034662605
-
Inactivation of the 14-3-3 sigma gene is associated with 5′ CpG island hypermethylation in human cancers
-
Suzuki,H. et al. (2000) Inactivation of the 14-3-3 sigma gene is associated with 5′ CpG island hypermethylation in human cancers. Cancer Res., 60, 4353-4357.
-
(2000)
Cancer Res
, vol.60
, pp. 4353-4357
-
-
Suzuki, H.1
-
7
-
-
0029114538
-
Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas
-
Yoshiura,K. et al. (1995) Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas. Proc. Natl Acad. Sci. USA, 92, 7416-7419.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 7416-7419
-
-
Yoshiura, K.1
-
8
-
-
33751351899
-
Identification of DFNA5 as a target of epigenetic inactivation in gastric cancer
-
Akino,K. et al. (2007) Identification of DFNA5 as a target of epigenetic inactivation in gastric cancer. Cancer Sci., 98, 88-95.
-
(2007)
Cancer Sci
, vol.98
, pp. 88-95
-
-
Akino, K.1
-
9
-
-
0037112529
-
Identification of silencing of nine genes in human gastric cancers
-
Kaneda,A. et al. (2002) Identification of silencing of nine genes in human gastric cancers. Cancer Res., 62, 6645-6650.
-
(2002)
Cancer Res
, vol.62
, pp. 6645-6650
-
-
Kaneda, A.1
-
10
-
-
32944459562
-
High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk
-
Maekita,T. et al. (2006) High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk. Clin. Cancer Res., 12, 989-995.
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 989-995
-
-
Maekita, T.1
-
11
-
-
0037805547
-
RAS oncogenes: The first 30 years
-
Malumbres,M. et al. (2003) RAS oncogenes: The first 30 years. Nat. Rev. Cancer, 3, 459-465.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 459-465
-
-
Malumbres, M.1
-
12
-
-
0037194728
-
Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status
-
Rajagopalan,H. et al. (2002) Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status. Nature, 418, 934.
-
(2002)
Nature
, vol.418
, pp. 934
-
-
Rajagopalan, H.1
-
13
-
-
0042885906
-
BRAF as a potential therapeutic target in melanoma and other malignancies
-
Tuveson,D.A. et al. (2003) BRAF as a potential therapeutic target in melanoma and other malignancies. Cancer Cell, 4, 95-98.
-
(2003)
Cancer Cell
, vol.4
, pp. 95-98
-
-
Tuveson, D.A.1
-
14
-
-
0842263902
-
Mutational analysis of BRAF and K-ras in gastric cancers: Absence of BRAF mutations in gastric cancers
-
Kim,I.J. et al. (2003) Mutational analysis of BRAF and K-ras in gastric cancers: Absence of BRAF mutations in gastric cancers. Hum. Genet., 114, 118-120.
-
(2003)
Hum. Genet
, vol.114
, pp. 118-120
-
-
Kim, I.J.1
-
15
-
-
0033918563
-
Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3
-
Dammann,R. et al. (2000) Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3. Nat. Genet., 25, 315-319.
-
(2000)
Nat. Genet
, vol.25
, pp. 315-319
-
-
Dammann, R.1
-
16
-
-
0035300429
-
Hypermethylation of the cpG island of Ras association domain family 1A (RASSF1A), a putative tumor suppressor gene from the 3p21.3 locus, occurs in a large percentage of human breast cancers
-
Dammann,R. et al. (2001) Hypermethylation of the cpG island of Ras association domain family 1A (RASSF1A), a putative tumor suppressor gene from the 3p21.3 locus, occurs in a large percentage of human breast cancers. Cancer Res., 61, 3105-3109.
-
(2001)
Cancer Res
, vol.61
, pp. 3105-3109
-
-
Dammann, R.1
-
17
-
-
22344435817
-
The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer
-
Akino,K. et al. (2005) The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer. Gastroenterology 129, 156-169.
-
(2005)
Gastroenterology
, vol.129
, pp. 156-169
-
-
Akino, K.1
-
18
-
-
34548674452
-
RASSF6 is a novel member of the RASSF family of tumor suppressors
-
Allen,N.P. et al. (2007) RASSF6 is a novel member of the RASSF family of tumor suppressors. Oncogene, 26, 6203-6211.
-
(2007)
Oncogene
, vol.26
, pp. 6203-6211
-
-
Allen, N.P.1
-
19
-
-
9244228001
-
RASSF4/AD037 is a potential ras effector/ tumor suppressor of the RASSF family
-
Eckfeld,K. et al. (2004) RASSF4/AD037 is a potential ras effector/ tumor suppressor of the RASSF family. Cancer Res., 64, 8688-8693.
-
(2004)
Cancer Res
, vol.64
, pp. 8688-8693
-
-
Eckfeld, K.1
-
20
-
-
28644450906
-
RASSF2, a potential tumour suppressor, is silenced by CpG island hypermethylation in gastric cancer
-
Endoh,M. et al. (2005) RASSF2, a potential tumour suppressor, is silenced by CpG island hypermethylation in gastric cancer. Br. J. Cancer, 93, 1395-1399.
-
(2005)
Br. J. Cancer
, vol.93
, pp. 1395-1399
-
-
Endoh, M.1
-
21
-
-
33745616508
-
Identification of RASSF8 as a candidate lung tumor suppressor gene
-
Falvella,F.S. et al. (2006) Identification of RASSF8 as a candidate lung tumor suppressor gene. Oncogene, 25, 3934-3938.
-
(2006)
Oncogene
, vol.25
, pp. 3934-3938
-
-
Falvella, F.S.1
-
22
-
-
20544445183
-
CpG island promoter hypermethylation of a novel Ras-effector gene RASSF2A is an early event in colon carcinogenesis and correlates inversely with K-ras mutations
-
Hesson,L.B. et al. (2005) CpG island promoter hypermethylation of a novel Ras-effector gene RASSF2A is an early event in colon carcinogenesis and correlates inversely with K-ras mutations. Oncogene, 24, 3987-3994.
-
(2005)
Oncogene
, vol.24
, pp. 3987-3994
-
-
Hesson, L.B.1
-
23
-
-
34548277011
-
Epigenetic inactivation of the RAS-effector gene RASSF2 in lung cancers
-
Kaira,K. et al. (2007) Epigenetic inactivation of the RAS-effector gene RASSF2 in lung cancers. Int. J. Oncol., 31, 169-173.
-
(2007)
Int. J. Oncol
, vol.31
, pp. 169-173
-
-
Kaira, K.1
-
24
-
-
0037129308
-
RASSF3 and NORE 1: Identification and cloning of two human homologues of the putative tumor suppressor gene RASSF1
-
Tommasi,S. et al. (2002) RASSF3 and NORE 1: Identification and cloning of two human homologues of the putative tumor suppressor gene RASSF1. Oncogene, 21, 2713-2720.
-
(2002)
Oncogene
, vol.21
, pp. 2713-2720
-
-
Tommasi, S.1
-
25
-
-
33845400874
-
Inactivation of RASSF2A by promoter methylation correlates with lymph node metastasis in nasopharyngeal carcinoma
-
Zhang,Z. et al. (2007) Inactivation of RASSF2A by promoter methylation correlates with lymph node metastasis in nasopharyngeal carcinoma. Int. J. Cancer, 120, 32-38.
-
(2007)
Int. J. Cancer
, vol.120
, pp. 32-38
-
-
Zhang, Z.1
-
26
-
-
33744505111
-
Norel and RASSFI regulation of cell proliferation and of the MST1/2 kinases
-
Avruch,J. et al. (2005) Norel and RASSFI regulation of cell proliferation and of the MST1/2 kinases. Meth. Enzymol., 407 290-310.
-
(2005)
Meth. Enzymol
, vol.407
, pp. 290-310
-
-
Avruch, J.1
-
27
-
-
0037007119
-
Cell signaling: Life or death decisions of ras proteins
-
Feig,L.A. et al. (2002) Cell signaling: Life or death decisions of ras proteins. Curr. Biol., 12, R259-R261.
-
(2002)
Curr. Biol
, vol.12
-
-
Feig, L.A.1
-
28
-
-
35148841871
-
Frequent hypermethylation of MST1 and MST2 in soft fissue sarcoma
-
Seidel,C. et al. (2007) Frequent hypermethylation of MST1 and MST2 in soft fissue sarcoma. Mol. Carcinog, 46, 865-871.
-
(2007)
Mol. Carcinog
, vol.46
, pp. 865-871
-
-
Seidel, C.1
-
29
-
-
0025966694
-
Establishment and characterization of human signet ring cell gastric carcinoma cell lines with amplification of the c-myc oncogene
-
Yanagihara,K. et al. (1991) Establishment and characterization of human signet ring cell gastric carcinoma cell lines with amplification of the c-myc oncogene. Cancer Res., 51, 381-386.
-
(1991)
Cancer Res
, vol.51
, pp. 381-386
-
-
Yanagihara, K.1
-
30
-
-
0027373686
-
Antiproliferative effects of isoflavones on human cancer cell lines established from the gastrointestinal tract
-
Yanagihara,K. et al. (1993) Antiproliferative effects of isoflavones on human cancer cell lines established from the gastrointestinal tract. Cancer Res., 53, 5815-5821.
-
(1993)
Cancer Res
, vol.53
, pp. 5815-5821
-
-
Yanagihara, K.1
-
31
-
-
33645801603
-
Genetic, epigenetic, and clinicopathologic features of gastric carcinomas with the CpG island methylator phenotype and an association with Epstein-Barr virus
-
Kusano,M. et al. (2006) Genetic, epigenetic, and clinicopathologic features of gastric carcinomas with the CpG island methylator phenotype and an association with Epstein-Barr virus. Cancer, 106. 1467-1479.
-
(2006)
Cancer
, vol.106
, pp. 1467-1479
-
-
Kusano, M.1
-
32
-
-
0028096611
-
High sensitivity mapping of Methylated cytosines
-
Clark,S.J. et al. (1994) High sensitivity mapping of Methylated cytosines. Nucleic Acids Res., 22, 2990-2997.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 2990-2997
-
-
Clark, S.J.1
-
33
-
-
34247273521
-
Rare CpG island methylator phenotype in ulcerative colitis-associated neoplasim
-
Konishi,K. et al. (2007) Rare CpG island methylator phenotype in ulcerative colitis-associated neoplasim. Gastroenterology, 132 1254-1260.
-
(2007)
Gastroenterology
, vol.132
, pp. 1254-1260
-
-
Konishi, K.1
-
34
-
-
2342557977
-
A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements
-
Yang,A.S. et al. (2004) A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements. Nucleic Acids Res., 32, e38.
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Yang, A.S.1
-
35
-
-
0034052378
-
Adenovirus-mediated transfer of p53-related genes induces apoptosis of human cancer cells
-
Ishida,S. et al. (2000) Adenovirus-mediated transfer of p53-related genes induces apoptosis of human cancer cells. Jpn. J. Cancer Res., 91, 174-180.
-
(2000)
Jpn. J. Cancer Res
, vol.91
, pp. 174-180
-
-
Ishida, S.1
-
36
-
-
0034834092
-
Adenovirus-mediated transfer of the p53 family genes, p73 and p51/p63 induces cell cycle arrest and apoptosis in colorectal cancer cell lines: Potential application to gene therapy of colorectal cancer
-
Sasaki,Y et al. (2001) Adenovirus-mediated transfer of the p53 family genes, p73 and p51/p63 induces cell cycle arrest and apoptosis in colorectal cancer cell lines: Potential application to gene therapy of colorectal cancer. Gene Ther., 8, 1401-1408.
-
(2001)
Gene Ther
, vol.8
, pp. 1401-1408
-
-
Sasaki, Y.1
-
37
-
-
34047116826
-
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
-
Weber,M. et al. (2007) Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat. Genet., 39, 457-466.
-
(2007)
Nat. Genet
, vol.39
, pp. 457-466
-
-
Weber, M.1
-
38
-
-
0032483404
-
Oxidative stress activates the human histidine decarboxylase promoter in AGS gastric cancer cells
-
Hocker,M. et al. (1998) Oxidative stress activates the human histidine decarboxylase promoter in AGS gastric cancer cells. J. Biol. Chem., 273, 23046-23054.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 23046-23054
-
-
Hocker, M.1
-
39
-
-
20544440341
-
Transformed immortalized gastric epithelial cells by virulence factor CagA of Helicobacter pylori through Erk mitogen-activated protein kinase pathway
-
Zhu,Y. et al. (2005) Transformed immortalized gastric epithelial cells by virulence factor CagA of Helicobacter pylori through Erk mitogen-activated protein kinase pathway. Oncogene, 24, 3886-3895.
-
(2005)
Oncogene
, vol.24
, pp. 3886-3895
-
-
Zhu, Y.1
-
40
-
-
31544449750
-
Somatic mutations of ERBB2 kinase domain in gastric, colorectal, and breast carcinomas
-
Lee,J.W. et al. (2006) Somatic mutations of ERBB2 kinase domain in gastric, colorectal, and breast carcinomas. Clin. Cancer Res., 12, 57-61.
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 57-61
-
-
Lee, J.W.1
-
41
-
-
0024308804
-
Amplification, overexpression, and rearrangement of the erbB-2 protooncogene in primary human stomach carcinomas
-
Park,J.B. et al. (1989) Amplification, overexpression, and rearrangement of the erbB-2 protooncogene in primary human stomach carcinomas. Cancer Res., 49, 6605-6609.
-
(1989)
Cancer Res
, vol.49
, pp. 6605-6609
-
-
Park, J.B.1
-
42
-
-
21544483241
-
Methylation of the tumor suppressor gene RASSF1A in human tumors
-
Pfeifer,G.P. et al. (2005) Methylation of the tumor suppressor gene RASSF1A in human tumors. Biochemistry (Mosc.), 70, 576-583.
-
(2005)
Biochemistry (Mosc.)
, vol.70
, pp. 576-583
-
-
Pfeifer, G.P.1
-
43
-
-
0037069690
-
Rho GTPases in cell biology
-
Etienne-Manneville,S. et al. (2002) Rho GTPases in cell biology. Nature, 420, 629-635.
-
(2002)
Nature
, vol.420
, pp. 629-635
-
-
Etienne-Manneville, S.1
-
44
-
-
23044453047
-
Inhibition of c-Jun-N-terminal-kinase sensitizes tumor cells to CD95-induced apoptosis and induces G2/M cell cycle arrest
-
Kuntzen,C. et al. (2005) Inhibition of c-Jun-N-terminal-kinase sensitizes tumor cells to CD95-induced apoptosis and induces G2/M cell cycle arrest. Cancer Res., 65, 6780-6788.
-
(2005)
Cancer Res
, vol.65
, pp. 6780-6788
-
-
Kuntzen, C.1
-
45
-
-
7944223098
-
Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis
-
Sparmann,A. et al. (2004) Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis. Cancer Cell 6, 447-458.
-
(2004)
Cancer Cell
, vol.6
, pp. 447-458
-
-
Sparmann, A.1
-
46
-
-
2342524099
-
CXC chemokines. in angiogenesis of cancer
-
Strieter,R.M. et al. (2004) CXC chemokines. in angiogenesis of cancer. Semin. Cancer Biol., 14, 195-200.
-
(2004)
Semin. Cancer Biol
, vol.14
, pp. 195-200
-
-
Strieter, R.M.1
-
47
-
-
33646477970
-
Involvement of chemokine receptor CCR6 in colorectal cancer metastasis
-
Rubie,C. et al. (2006) Involvement of chemokine receptor CCR6 in colorectal cancer metastasis. Tumour Biol., 27, 166-174.
-
(2006)
Tumour Biol
, vol.27
, pp. 166-174
-
-
Rubie, C.1
-
48
-
-
0035813187
-
The high molecular weight urinary matrix metalloproteinase (MMP) activity is a complex of gelatinase B/MMP-9 and neutrophil gelatinase-associated lipocalin (NGAL). Modulation of MMP-9 activity by NGAL
-
Yan,L. et al. (2001) The high molecular weight urinary matrix metalloproteinase (MMP) activity is a complex of gelatinase B/MMP-9 and neutrophil gelatinase-associated lipocalin (NGAL). Modulation of MMP-9 activity by NGAL. J. Biol. Chem.. 276. 37258-37265.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 37258-37265
-
-
Yan, L.1
-
49
-
-
1542319832
-
Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers
-
Etoh,T. et al. (2004) Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers. Am. J. Pathol., 164, 689-699.
-
(2004)
Am. J. Pathol
, vol.164
, pp. 689-699
-
-
Etoh, T.1
-
50
-
-
33846227472
-
Activation of DNA methyltransferase 1 by EBV LMP1 Involves c-Jun NH(2)-terminal kinase signaling
-
Tsai,C.L. et al. (2006) Activation of DNA methyltransferase 1 by EBV LMP1 Involves c-Jun NH(2)-terminal kinase signaling. Cancer Res. 66, 11668-11676.
-
(2006)
Cancer Res
, vol.66
, pp. 11668-11676
-
-
Tsai, C.L.1
|