Multimodal imaging demonstrates concomitant changes in bone and cartilage after destabilisation of the medial meniscus and increased joint laxity

Osteoarthritis and Cartilage

Volumn 19, Issue 2, 2011, Pages 163-170

  Moodie, J P ^a   Stok, K S ^b   Muller R ^b   Vincent, T L ^a   Shefelbine, S J ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b ETH ZURICH   (Switzerland)

Author keywords

Animal studies; Osteoarthritis; Subchondral bone

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE ATROPHY; BONE MATURATION; BONE REMODELING; CARTILAGE DEGENERATION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; GROWTH PLATE; JOINT LAXITY; LEG; LIMB; MALE; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NONHUMAN; OSTEOARTHRITIS; OSTEOLYSIS; PRIORITY JOURNAL; RANGE OF MOTION; TIBIA; TRABECULAR BONE;

ANALYSIS OF VARIANCE; ANIMALS; BONE AND BONES; CARTILAGE, ARTICULAR; DISEASE MODELS, ANIMAL; IMAGING, THREE-DIMENSIONAL; MALE; MENISCI, TIBIAL; MICE; MICE, INBRED BALB C; OSTEOARTHRITIS; RANGE OF MOTION, ARTICULAR;

EID: 79151473474     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2010.11.006     Document Type: Article

References (44)

1. Buckwalter J.A., Martin J. Degenerative joint disease. Clin Symp 1995, 47(2):1-32.
2. Brown T.D., Johnston R.C., Saltzman C.L., Marsh J.L., Buckwalter J.A. Posttraumatic osteoarthritis: a first estimate of incidence, prevalence, and burden of disease. J Orthop Trauma 2006, 20(10):739-744.
3. Nuki G. Osteoarthritis: a problem of joint failure. Z Rheumatol 1999, 58(3):142.
4. Vincent T.L., Watt F.E. Osteoarthritis. Medicine 2010, 38(3):151-156.
5. Moskowitz R.W. Bone remodeling in osteoarthritis: subchondral and osteophytic responses. Osteoarthritis Cartilage 1999, 7(3):323.
6. Glasson S.S., Blanchet T.J., Morris E.A. The surgical destabilization of the medial meniscus (DMM) model of osteoarthritis in the 129/SvEv mouse. Osteoarthritis Cartilage 2007, 15(9):1061-1069.
7. Glasson S.S. Characterization of and osteoarthritis susceptibility in ADAMTS-4-knockout mice. Arthritis Rheum 2004, 50(8):2547.
8. Glasson S.S., Askew R., Sheppard B., Carito B., Blanchet T., Ma H.L., et al. Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis. Nature 2005, 434(7033):644-648.
9. Ma H.L., Blanchet T.J., Peluso D., Hopkins B., Morris E.A., Glasson S.S. Osteoarthritis severity is sex dependent in a surgical mouse model. Osteoarthritis Cartilage 2007, 15(6):695-700.
10. Shi-Lu C., Yasunobu S., Annika B., Celia M., Julia I., Jeremy S., et al. Fibroblast growth factor 2 is an intrinsic chondroprotective agent that suppresses ADAMTS-5 and delays cartilage degradation in murine osteoarthritis. Arthritis Rheum 2009, 60(7):2019-2027.
11. Imhof H., Breitenseher M., Kainberger F., Rand T., Trattnig S. Importance of subchondral bone to articular cartilage in health and disease. Top Magn Reson Imaging 1999, 10(3):180-192.
12. Botter S.M., Glasson S.S., Hopkins B., Clockaerts S., Weinans H., van Leeuwen J.P.T.M., et al. ADAMTS5-/- mice have less subchondral bone changes after induction of osteoarthritis through surgical instability: implications for a link between cartilage and subchondral bone changes. Osteoarthritis Cartilage 2009, 17(5):636-645.
13. Appleton C.T., McErlain D., Pitelka V., Schwartz N., Bernier S., Henry J., et al. Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritis. Arthritis Res Ther 2007, 9(1):R13.
14. Radin E.L., Rose R.M. Role of subchondral bone in the initiation and progression of cartilage damage. Clin Orthop Relat Res 1986, 213:34-40.
15. Burr D.B. The importance of subchondral bone in osteoarthrosis. Curr Opin Rheumatol 1998, 10(3):256-262.
16. Bailey A.J., Buckland-Wright C., Metz D. The role of bone in osteoarthritis. Age Ageing 2001, 30(5):374.
17. Botter S.M., van Osch G.J.V.M., Waarsing J.H., van der Linden J.C., Verhaar J.A.N., Pols H.A.P., et al. Cartilage damage pattern in relation to subchondral plate thickness in a collagenase-induced model of osteoarthritis. Osteoarthritis Cartilage 2008, 16(4):506.
18. Blumenkrantz G., Lindsey C.T., Dunn T.C., Jin H., Ries M.D., Link T.M., et al. A pilot, two-year longitudinal study of the interrelationship between trabecular bone and articular cartilage in the osteoarthritic knee. Osteoarthritis Cartilage 2004, 12(12):997.
19. McDermott I.D., Amis A.A. The consequences of meniscectomy. J Bone Joint Surg Br 2006 December 1, 88-B(12):1549-1556.
20. van der Esch M., Steultjens M., Harlaar J., Wolterbeek N., Knol D.L., Dekker J. Knee varus-valgus motion during gait - a measure of joint stability in patients with osteoarthritis?. Osteoarthritis Cartilage 2008, 16(4):522-525.
21. Blankevoort L., van Osch G.J., Janssen B., Hekman E.E. In vitro laxity-testers for knee joints of mice. J Biomech 1996, 29(6):799.
22. van Osch G.J., Blankevoort L., van der Kraan P.M., Janssen B., Hekman E., Huiskes R., et al. Laxity characteristics of normal and pathological murine knee joints in vitro. J Orthop Res 1995, 13(5):783.
23. Stok K.S., Pelled G., Zilberman Y., Kallai I., Goldhahn J., Gazit D., et al. Revealing the interplay of bone and cartilage in osteoarthritis through multimodal imaging of murine joints. Bone 2009, 45(3):414-422.
24. Schmid B. ImageJ 3D Viewer [cited]; Available from:. http://132.187.25.13/home/%3Fcategory%3DDownload&page%3DViewer3D.
25. Dougherty R. Computing local thickness of 3D structures with ImageJ. Microsc Microanal 2007, 13(S02E):1678.
26. Doube MKM, Arganda-Carreras I, Cordelires F, Dougherty RP, Jackson JSB, Hutchinson JR, et-al. Extensible bone image analysis in ImageJ. 2010 [updated 2010; cited]; Available from: http://www.bonej.org.
27. Stok K.S., Pelled G., Zilberman Y., Kallai I., Gazit D., Mueller R. Whole joint imaging allows quantification of bone and cartilage degeneration in a murine model of osteoarthritis. Bone 2009, 44(Suppl 1). S156-7.
28. Ridler T.W. Picture thresholding using an iterative selection method. IEEE Trans Syst Man Cybern B Cybern 1978, 8(8):630.
29. 53rd Annual Meeting of the Orthopaedic Research Society 2007, ORS, San Diego. S. Chia, J.J. Inglis, D. Essex, D. Preston, R. Williams, J. Saklatvala (Eds.).
30. Inglis J.J., McNamee K.E., Chia S.L., Essex D., Feldmann M., Williams R.O., et al. Regulation of pain sensitivity in experimental osteoarthritis by the endogenous peripheral opioid system. Arthritis Rheum 2008, 58(10):3110.
31. Parfitt A.M. Bone histomorphometry: standardization of nomenclature, symbols and units (summary of proposed system). Bone 1988, 9(1):67-69.
32. Bailey A.J., Mansell J.P. Do subchondral bone changes exacerbate or precede articular cartilage destruction in osteoarthritis of the elderly?. Gerontology 1997, 43(5):296-304.
33. Brandt K.D., Radin E.L., Dieppe P.A., van de Putte L. Yet more evidence that osteoarthritis is not a cartilage disease. Ann Rheum Dis 2006, 65(10):1261.
34. Beamer W.G., Donahue L.R., Rosen C.J., Baylink D.J. Genetic variability in adult bone density among inbred strains of mice. Bone 1996, 18(5):397.
35. Laboratory TJ. JAX® Mice Database. 2009 [updated 2009; cited]; Available from: http://jaxmice.jax.org/query/f%3Fp%3D205:1:3633989967120115798.
36. Tomoya M., Hiroshi H., Toru O., Makoto E., Ryota T. Role of subchondral bone in osteoarthritis development: a comparative study of two strains of guinea pigs with and without spontaneously occurring osteoarthritis. Arthritis Rheum 2007, 56(10):3366-3374.
37. Akhter M.P., Cullen D.M., Pedersen E.A., Kimmel D.B., Recker R.R. Bone response to in vivo mechanical loading in two breeds of mice. Calcif Tissue Int 1998, 63(5):442.
38. Judex S., Donahue L.R., Rubin C. Genetic predisposition to low bone mass is paralleled by an enhanced sensitivity to signals anabolic to the skeleton. FASEB J 2002 Published online June 21, 2002:01-0913fje.
39. Webster D., Wasserman E., Ehrbar M., Weber F., Bab I., Müller R. Mechanical loading of mouse caudal vertebrae increases trabecular and cortical bone mass-dependence on dose and genotype. Biomech Model Mechanobiol 2010, 9(6):737-747.
40. Kadri A. Osteoprotegerin inhibits cartilage degradation through an effect on trabecular bone in murine experimental osteoarthritis. Arthritis Rheum 2008, 58(8):2379.
41. Stok K., Müller R. Morphometric characterization of murine articular cartilage - novel application of confocal laser scanning microscopy. Microsc Res Tech 2009, 72(9):650-658.
42. Stockwell R.A. The interrelationship of cell density and cartilage thickness in mammalian articular cartilage. J Anat 1971, 109(Pt 3):411.
43. William H.S. Scale effects in animal joints. I. articular cartilage thickness and compressive stress. Arthritis Rheum 1970, 13(3):244-255.
44. Cao L., Youn I., Guilak F., Setton L.A. Compressive properties of mouse articular cartilage determined in a novel micro-indentation test method and biphasic finite element model. J Biomech Eng 2006, 128(5):766-771.