Production of human milk fat substitute with medium-chain fatty acids by lipase-catalyzed acidolysis: Optimization by response surface methodology

LWT

Volumn 44, Issue 4, 2011, Pages 999-1004

  Ilyasoglu, Huri ^a   Gultekin Ozguven, Mine ^b   Ozcelik, Beraat ^b  

^a GUMUSHANE UNIVERSITY   (Turkey)

^b ISTANBUL TECHNICAL UNIVERSITY   (Turkey)

Author keywords

Hazelnut oil; Human milk fat substitute; Medium chain fatty acids; Response surface methodology

Indexed keywords

CATALYSIS; DAIRIES; LIPIDS; MOLAR RATIO; OILS AND FATS; SATURATED FATTY ACIDS; SUBSTRATES; SURFACE PROPERTIES; SURFACE REACTIONS;

HAZELNUT OIL; HUMAN MILK FAT SUBSTITUTES; LIPASE CATALYZED ACIDOLYSIS; MEDIUM-CHAIN FATTY ACIDS; REACTION CONDITIONS; REACTION SUBSTRATES; REACTION TEMPERATURE; RESPONSE SURFACE METHODOLOGY;

PALMITIC ACID;

CORYLUS;

EID: 79151470870     PISSN: 00236438     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lwt.2010.11.027     Document Type: Article

References (21)

1. Can A., Ozcelik B. Enrichment of hazelnut oil with long chain n-3 PUFA by lipase-catalyzed acidolysis: optimization by response surface methodology. Journal of American Oil Chemist Society 2005, 82:27-32.
2. Che Man Y.B., Manaf M.A. Medium-chained triacylglycerols. Nutraceutical and specialtylipids and co-their products 2006, 27-56. Taylor & Francis Group, LLC. F. Shahidi (Ed.).
3. Isaacs C.E., Litov R.E., Thormar H. Antimicrobial activity of lipids added to human milk, infant formula, and bovine milk. Journal of Nutritional Biochemistry 1995, 6:362-366.
4. Jennings B.H., Akoh C.C. Enzymatic modification of triacylglycerols of high eicosapentaenoic and docosahexaenoic acids content to produce structured lipids. Journal of American Oil Chemist Society 1999, 76:1133-1137.
5. Jimenez J.M., Esteban L., Robles A., Hita E., Gonzales P.A., Munio M.M., Molina E. Productions of triacylglycerols rich in palmitic acid at 2 position as intermediates for the synthesis of human milk fat substitutes by enzymatic acidolysis. Process Biochemistry 2010, 45:407-414.
6. Karabulut I., Turan S., Vural H., Kayahan M. Human milk fat substitute produced by enzymatic interesterification of vegetable oil blend. Food Technology and Biotechnology 2007, 45:434-438.
7. Li Y., Mu H., Andersen J.E.T., Xu X., Meyer O., Orngreen A. New human milk fat substitutes from butter fat to improve fat absorption. Food Research International 2010, 43:739-744.
8. Maduko C.O., Akoh C.C., Park W. Enzymatic production of infant milk fat anologs containing palmitic acid: optimization of reactions by response surface methodology. Journal of Dairy Science 2007, 90:2147-2154.
9. Mu H., Xu X., Hoy C.E. Production of specific-structured triacylglycerols by lipase-catalyzed interesterification in a laboratory-scale continous reactor. Journal of American Oil Chemist Society 1998, 75:1187-1193.
10. Nielsen S.N., Yang T., Xu X., Jacobsen C. Production and oxidative stability of a human milk fat substitute produced from lard by enzyme technology in a pilot packed-bed reactor. Food Chemistry 2006, 94:53-60.
11. O'Shea M., Geritsen J., Moheda I. Clinical benefit of a structured lipid (betapolTM) in infant formula. Handbook of functional lipids 2006, 261-278. Taylor and Franchis Group, LLC. C.C. Akoh (Ed.).
12. Ozcelik B., Karaali A., Sahin Yesilcubuk N., Kahveci D. Production of structured lipid by biotechnological methods 2008, (Turkish Scientific Research Center) Project No: 104M410, TUBITAK, Ankara.
13. Pina-Rodriguez A.M., Akoh C. Synthesis and characterization of a structured lipid from amaranth oil as a partial fat substitute in milk-based infant formula. Journal of Agricultural and Food Chemistry 2009, 57:6748-6756.
14. Sørensen A.M., Xu X., Zhang L., Kristensen J.B., Jacobsen C. Human milk fat substitute from butterfat: production by enzymatic interesterification and evaluation of oxidative stability. Journal of American Oil Chemist Society 2009, 10.1007/s11746-009-1479-z.
15. Sahin N., Akoh C.C., Karaali A. Enzymatic production of human milk fat substitutes containing g-linolenic acid: optimization of reactions by response surface methodology. Journal of American Oil Chemist Society 2005, 82:549-557.
16. Senenayake S.P.J., Shahidi F. Enzymatic incorporation of docosahexaenoic acid into borage oil. Journal of American Oil ChemistSociety 1999, 76:1009-1015.
17. Srivastava A., Akoh C.C., Chang S., Lee G., Shaw J. Candida rugosa lipase LIP1-catalyzed transesterification to produce human milk fat substitute. Journal of Agricultural and Food Chemistry 2006, 54:5175-5181.
18. Wang Y.-H., Mai Q.-Y., Qin X.-L., Yang B., Wang Z.-L., Chen H.-T. Establishment of an evaluation model for human milk fat substitutes. Journal of Agricultural and Food Chemistry 2010, 58:642-649.
19. Xu X., Skands A.R.H., Hoy C.E., Mu H., Balchen S., Adler-Nissen J. Production of specific-structured triacylglycerols by enzymatic interesterification: Elucidation of acyl migration by response surface design. Journal of American Oil Chemist Society 1998, 75:1179-1186.
20. Yang T., Xu X., He C., Li L. Lipase-catalyzed modification of lard to produce human milk fat substitutes. Food Chemistry 2003, 80:473-481.
21. Zhao H., Lu Z., Lu F., Bie X., Liu Z., Zeng X. Lipase-catalyzed acidolysis of lard with caprylic acid to produce structured lipids. International Journal of Food Science and Technology 2006, 41:1027-1032.