Enzymatic production of infant milk fat analogs containing palmitic acid: Optimization of reactions by response surface methodology

Journal of Dairy Science

Volumn 90, Issue 5, 2007, Pages 2147-2154

  Maduko, C O ^a   Akoh, C C ^a   Park, Y W ^a,b  

^a UNIVERSITY OF GEORGIA   (United States)

^b FORT VALLEY STATE UNIVERSITY   (United States)

Author keywords

Enzymatic interesterification; Infant milk fat; Response surface methodology; sn 1,3 specific lipase

Indexed keywords

GLYCINE MAX; INSECTIVORA; RHIZOMUCOR; RHIZOMUCOR MIEHEI;

EID: 35748974818     PISSN: 00220302     EISSN: 15253198     Source Type: Journal    
DOI: 10.3168/jds.2006-686     Document Type: Article

References (22)

1. Akoh, C. C., S. Sellappan, L. B. Fomuso, and V. V. Yankah. 2002. Enzymatic synthesis of structured lipids. Pages 433-460 in Lipid Biotechnology. T. M. Kuo and H. W. Gardner, ed. Marcel Dekker, New York, NY.
2. Dordick, J. S. 1989. Enzymatic catalysis in monophasic organic solvents. Enzyme Microb. Technol. 11:194-211.
3. Innis, S. M., R. Dyer, P. Quinlan, and D. Dierson-Schade. 1995. Palmitic acid is absorbed as sn-2 monopalmitin from milk and formula with rearranged triacylglycerols and results in increased plasma triglyceride sn-2 and cholesterol ester palmitate in piglets. J. Nutr. 125:73-81.
4. Jennings, B. H., and C. C. Akoh. 1999. Enzymatic modification of triacylglycerols of high eicosapentaenoic and docosahexaenoic acids content to produce structured lipids. J. Am. Oil Chem. Soc. 76:1133-1137.
5. Jensen, R. G. 1989. Lipids in human milk-Composition and fat-soluble vitamins. Pages 157-208 in Textbook of Gastroenterology and Nutrition in Infancy. 2nd ed. E. Lebenthal, ed. Raven Press, New York, NY.
6. Kennedy, K., M. S. Fewtrell, R. Morley, R. Abott, P. T. Quinlan, J. C. K. Wells, J. G. Bindels, and A. Lucas. 1999. Double-blind, randomized trial of a synthetic triacylglycerol in formula-fed term infants: Effects on stool biochemistry, stool characteristics and bone mineralization. Am. J. Clin. Nutr. 70:920-927.
7. Lumor, S. E., and C. C. Akoh. 2005. Enzymatic incorporation of stearic acid into a blend of palm olein and palm kernel oil: Optimization by response surface methodology. J. Am. Oil Chem. Soc. 82:421-426.
8. Maduko, C. O., C. C. Akoh, and Y. W. Park. 2006a. Enzymatic interesterification of tripalmitin with vegetable oil blends to produce caprine milk infant formula analogs. 2006 IFT Annual Mtg., Abstr. 034-08. Institute of Food Technologists, Chicago, IL.
9. Maduko, C. O., C. C. Akoh, and Y. W. Park. 2006b. Comparison of the fatty acid distributions among different vegetable oil blends toward infant milk formulation. J. Dairy Sci. 89(Suppl. 1):385. (Abstr.)
10. Maduko, C. O., D. C. Peck, R. T. Toledo, and Y. W. Park. 2005. Modification of caprine milk fat to simulate fatty acid profile of human milk. 2005 IFT Annual Mtg., Abstr. 31-9. Institute of Food Technologists, Chicago, IL.
11. Megraud, F., G. Boudara, K. Bessand, S. Bensid, F. Dabis, R. Soltana, and M. Touhahmi. 1990. Incidence of bacterial infection in infants in Western Algeria and the possible protective role of breastfeeding. J. Epidemiol. Infect. 105:73-78.
12. Montgomery, D. C. 1997. Some aspects of generalized linear models for designed experiments. Pages 575-625 in Design and Analysis of Experiments. 4th ed. John Wiley and Sons, New York, NY.
13. Packard, V. S. 1982. Human milk and infant formula. Pages 140-175 in Infant Formula Composition, Formulation and Processing. Food Science and Technology, a series of monographs. G. F. Stewart, S. S. Schweigert, and J. Hawthorn, ed. Academic Press, New York, NY.
14. Paivi, A. L., V. M. Balcao, and F. X. Malcata. 2000. Kinetics and mechanisms of reactions catalyzed by immobilized lipases. Enzyme Microb. Technol. 27:187-204.
15. Quinlan, P. T., S. Lockton, J. Irwin, and A. L. Lucas. 1995. The relationship between stool hardness and stool composition in breast and formula-fed infants. J. Pediatr. Gastroenterol. Nutr. 20:81-90.
16. Sahin, N., C. C. Akoh, and A. Karaali. 2005a. Enzymatic production of human milk fat substitutes containing gamma-linoleic acid: Optimization of reactions by response surface methodology. J. Am. Oil Chem. Soc. 82:549-557.
17. Sahin, N., C. C. Akoh, and A. Karaali. 2005b. Lipase-catalyzed acidolysis of tripalmitin with hazelnut oil fatty acids and stearic acid to produce human milk fat substitutes. J. Agric. Food Chem. 53:5779-5783.
18. Sahin, N., C. C. Akoh, and A. Karaali. 2006. Human milk fat substitutes containing omega-3 fatty acids. J. Agric. Food Chem. 54:3717-3722.
19. United States Department of Agriculture (USDA). 1976. Composition of Foods. Agriculture Handbook Nos. 1,4, 9, 11, 16. USDA, Washington, DC.
20. Xu, X. 2000. Production of specific-structured triacylglycerols by lipase catalyzed reactions: A review. Eur. J. Lipid Sci. Technol. 102:287-303.
21. Xu, X., L. B. Fomuso, and C. C. Akoh. 2000. Modification of menhaden oil by enzymatic acidolysis to produce structured lipids: Optimization of response surface design in a packed bed reactor. J. Am. Oil Chem. 77:171-176.
22. Yang, T. K., X. Xu, C. He, and L. Li. 2003. Lipase-catalyzed modification of lard to produce human milk fat substitutes. J. Food Chem. 80:473-481.