Pseudoislets in stirred-suspension culture exhibit enhanced cell survival, propagation and insulin secretion

Journal of Biotechnology

Volumn 151, Issue 3, 2011, Pages 278-286

  Lock, Lye T ^a   Laychock, Suzanne G ^b   Tzanakakis, Emmanuel S ^a,c  

^a State University of New York   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

^c UNIVERSITY AT BUFFALO   (United States)

Author keywords

Cell viability; Apoptosis; Insulin secretion; Pseudoislets; Stirred suspension culture

Indexed keywords

APOPTOSIS; CELL VIABILITY; INSULIN SECRETION; PSEUDOISLETS; SUSPENSION CULTURES;

BIOCONVERSION; BIOREACTORS; CELL DEATH; GLUCOSE; INSULIN; MONOLAYERS;

CELL CULTURE;

CASPASE 2; CASPASE 8; CASPASE 9; GLUCOSE; INCRETIN; INSULIN; LACTATE DEHYDROGENASE; PROTEIN P21; PROTEIN P27;

ANIMAL CELL; APOPTOSIS; ARTICLE; BIOREACTOR; CELL FUNCTION; CELL PROLIFERATION; CELL SURVIVAL; CELL ULTRASTRUCTURE; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; FLOW CYTOMETRY; INSULIN RELEASE; MOUSE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSEUDOISLET; TRANSMISSION ELECTRON MICROSCOPY;

ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; BIOREACTORS; CELL CULTURE TECHNIQUES; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; HISTOCYTOCHEMISTRY; INSULIN; INSULIN-SECRETING CELLS; MICE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUSPENSIONS;

EID: 79151470838     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2010.12.015     Document Type: Article

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