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Volumn 85, Issue 4, 2011, Pages 1887-1892

The adenovirus E1b55K/E4orf6 complex induces degradation of the bloom helicase during infection

Author keywords

[No Author keywords available]

Indexed keywords

BLOOM SYNDROME HELICASE; E1B55K PROTEIN; E4ORF6 PROTEIN; GENE PRODUCT; RECQ HELICASE; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS PROTEIN;

EID: 78951470860     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02134-10     Document Type: Article
Times cited : (62)

References (73)
  • 1
    • 23844438197 scopus 로고    scopus 로고
    • Adenovirus type 5 E4orf3 protein targets the Mre11 complex to cytoplasmic aggresomes
    • Araujo, F. D., T. H. Stracker, C. T. Carson, D. V. Lee, and M. D. Weitzman. 2005. Adenovirus type 5 E4orf3 protein targets the Mre11 complex to cytoplasmic aggresomes. J. Virol. 79:11382-11391.
    • (2005) J. Virol. , vol.79 , pp. 11382-11391
    • Araujo, F.D.1    Stracker, T.H.2    Carson, C.T.3    Lee, D.V.4    Weitzman, M.D.5
  • 2
    • 0021363662 scopus 로고
    • Adenovirus type 5 early region 1b gene product is required for efficient shutoff of host protein synthesis
    • Babiss, L. E., and H. S. Ginsberg. 1984. Adenovirus type 5 early region 1b gene product is required for efficient shutoff of host protein synthesis. J. Virol. 50:202-212.
    • (1984) J. Virol. , vol.50 , pp. 202-212
    • Babiss, L.E.1    Ginsberg, H.S.2
  • 3
    • 34250894884 scopus 로고    scopus 로고
    • Adenovirus E4 34k and E1b 55k oncoproteins target host DNA ligase IV for proteasomal degradation
    • DOI 10.1128/JVI.00029-07
    • Baker, A., K. J. Rohleder, L. A. Hanakahi, and G. Ketner. 2007. Adenovirus E4 34k and E1b 55k oncoproteins target host DNA ligase IV for proteasomal degradation. J. Virol. 81:7034-7040. (Pubitemid 46986639)
    • (2007) Journal of Virology , vol.81 , Issue.13 , pp. 7034-7040
    • Baker, A.1    Rohleder, K.J.2    Hanakahi, L.A.3    Ketner, G.4
  • 4
    • 66149110933 scopus 로고    scopus 로고
    • Adenovirus E1B 55-kilodalton protein: Multiple roles in viral infection and cell transformation
    • Blackford, A. N., and R. J. Grand. 2009. Adenovirus E1B 55-kilodalton protein: multiple roles in viral infection and cell transformation. J. Virol. 83:4000-4012.
    • (2009) J. Virol. , vol.83 , pp. 4000-4012
    • Blackford, A.N.1    Grand, R.J.2
  • 5
    • 59349088768 scopus 로고    scopus 로고
    • Manipulation of the ubiquitin-proteasome pathway by small DNA tumor viruses
    • Blanchette, P., and P. E. Branton. 2009. Manipulation of the ubiquitin-proteasome pathway by small DNA tumor viruses. Virology 384:317-323.
    • (2009) Virology , vol.384 , pp. 317-323
    • Blanchette, P.1    Branton, P.E.2
  • 6
    • 6344234804 scopus 로고    scopus 로고
    • Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53
    • Blanchette, P., et al. 2004. Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53. Mol. Cell. Biol. 24:9619-9629.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 9619-9629
    • Blanchette, P.1
  • 7
    • 40149099594 scopus 로고    scopus 로고
    • Control of mRNA export by adenovirus E4orf6 and E1B55K proteins during productive infection requires E4orf6 ubiquitin ligase activity
    • DOI 10.1128/JVI.02309-07
    • Blanchette, P., et al. 2008. Control of mRNA export by adenovirus E4orf6 and E1B55K proteins during productive infection requires E4orf6 ubiquitin ligase activity. J. Virol. 82:2642-2651. (Pubitemid 351329155)
    • (2008) Journal of Virology , vol.82 , Issue.6 , pp. 2642-2651
    • Blanchette, P.1    Kindsmuller, K.2    Groitl, P.3    Dallaire, F.4    Speiseder, T.5    Branton, P.E.6    Dobner, T.7
  • 8
    • 56449090762 scopus 로고    scopus 로고
    • Rising from the RecQ-age: The role of human RecQ helicases in genome maintenance
    • Bohr, V. A. 2008. Rising from the RecQ-age: the role of human RecQ helicases in genome maintenance. Trends Biochem. Sci. 33:609-620.
    • (2008) Trends Biochem. Sci. , vol.33 , pp. 609-620
    • Bohr, V.A.1
  • 9
    • 0033604299 scopus 로고    scopus 로고
    • Adenovirus E4 34k and E4 11k inhibit double strand break repair and are physically associated with the cellular DNA-dependent protein kinase
    • DOI 10.1006/viro.1999.9866
    • Boyer, J., K. Rohleder, and G. Ketner. 1999. Adenovirus E4 34k and E4 11k inhibit double strand break repair and are physically associated with the cellular DNA-dependent protein kinase. Virology 263:307-312. (Pubitemid 29521523)
    • (1999) Virology , vol.263 , Issue.2 , pp. 307-312
    • Boyer, J.1    Rohleder, K.2    Ketner, G.3
  • 10
    • 0025037997 scopus 로고
    • Interaction of adenoviral E4 and E1b products in late gene expression
    • DOI 10.1016/0042-6822(90)90088-9
    • Bridge, E., and G. Ketner. 1990. Interaction of adenoviral E4 and E1b products in late gene expression. Virology 174:345-353. (Pubitemid 20060138)
    • (1990) Virology , vol.174 , Issue.2 , pp. 345-353
    • Bridge, E.1    Ketner, G.2
  • 11
    • 0024571586 scopus 로고
    • Redundant control of adenovirus late gene expression by early region 4
    • Bridge, E., and G. Ketner. 1989. Redundant control of adenovirus late gene expression by early region 4. J. Virol. 63:631-638.
    • (1989) J. Virol. , vol.63 , pp. 631-638
    • Bridge, E.1    Ketner, G.2
  • 13
    • 62649135141 scopus 로고    scopus 로고
    • Mislocalization of the MRN complex prevents ATR signaling during adenovirus infection
    • Carson, C. T., et al. 2009. Mislocalization of the MRN complex prevents ATR signaling during adenovirus infection. EMBO J. 28:652-662.
    • (2009) EMBO J. , vol.28 , pp. 652-662
    • Carson, C.T.1
  • 14
    • 0345732687 scopus 로고    scopus 로고
    • The Mre11 complex is required for ATM activation and the G2/M checkpoint
    • Carson, C. T., et al. 2003. The Mre11 complex is required for ATM activation and the G2/M checkpoint. EMBO J. 22:6610-6620.
    • (2003) EMBO J. , vol.22 , pp. 6610-6620
    • Carson, C.T.1
  • 15
    • 0034468690 scopus 로고    scopus 로고
    • A functional complex of adenovirus proteins E1B-55kDa and E4orf6 is necessary to modulate the expression level of p53 but not its transcriptional activity
    • Cathomen, T., and M. D. Weitzman. 2000. A functional complex of adenovirus proteins E1B-55kDa and E4orf6 is necessary to modulate the expression level of p53 but not its transcriptional activity. J. Virol. 74:11407-11412.
    • (2000) J. Virol. , vol.74 , pp. 11407-11412
    • Cathomen, T.1    Weitzman, M.D.2
  • 16
    • 0034066847 scopus 로고    scopus 로고
    • Retroviral expression of the NBS1 gene in cultured Nijmegen breakage syndrome cells restores normal radiation sensitivity and nuclear focus formation
    • Cerosaletti, K. M., et al. 2000. Retroviral expression of the NBS1 gene in cultured Nijmegen breakage syndrome cells restores normal radiation sensitivity and nuclear focus formation. Mutagenesis 15:281-286.
    • (2000) Mutagenesis , vol.15 , pp. 281-286
    • Cerosaletti, K.M.1
  • 17
    • 0346351375 scopus 로고
    • A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes
    • Chaganti, R. S., S. Schonberg, and J. German. 1974. A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes. Proc. Natl. Acad. Sci. U. S. A. 71:4508-4512.
    • (1974) Proc. Natl. Acad. Sci. U. S. A. , vol.71 , pp. 4508-4512
    • Chaganti, R.S.1    Schonberg, S.2    German, J.3
  • 18
    • 34547192058 scopus 로고    scopus 로고
    • BLM is required for faithful chromosome segregation and its localization defines a class of ultra-fine anaphase bridges
    • Chan, K. L., P. S. North, and I. D. Hickson. 2007. BLM is required for faithful chromosome segregation and its localization defines a class of ultra-fine anaphase bridges. EMBO J. 26:3397-3409.
    • (2007) EMBO J. , vol.26 , pp. 3397-3409
    • Chan, K.L.1    North, P.S.2    Hickson, I.D.3
  • 19
    • 68249117637 scopus 로고    scopus 로고
    • Viral manipulation of DNA repair and cell cycle checkpoints
    • Chaurushiya, M. S., and M. D. Weitzman. 2009. Viral manipulation of DNA repair and cell cycle checkpoints. DNA Repair (Amst.) 8:1166-1176.
    • (2009) DNA Repair (Amst.) , vol.8 , pp. 1166-1176
    • Chaurushiya, M.S.1    Weitzman, M.D.2
  • 20
    • 33750357800 scopus 로고    scopus 로고
    • Host cell DNA repair pathways in adeno-associated viral genome processing
    • Choi, V. W., D. M. McCarty, and R. J. Samulski. 2006. Host cell DNA repair pathways in adeno-associated viral genome processing. J. Virol. 80:10346-10356.
    • (2006) J. Virol. , vol.80 , pp. 10346-10356
    • Choi, V.W.1    McCarty, D.M.2    Samulski, R.J.3
  • 21
    • 69249209608 scopus 로고    scopus 로고
    • RecQ helicases: Multifunctional genome caretakers
    • Chu, W. K., and I. D. Hickson. 2009. RecQ helicases: multifunctional genome caretakers. Nat. Rev. Cancer 9:644-654.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 644-654
    • Chu, W.K.1    Hickson, I.D.2
  • 22
    • 66149114464 scopus 로고    scopus 로고
    • Identification of integrin alpha3 as a new substrate of the adenovirus E4orf6/E1B 55-kilodalton E3 ubiquitin ligase complex
    • Dallaire, F., P. Blanchette, P. Groitl, T. Dobner, and P. E. Branton. 2009. Identification of integrin alpha3 as a new substrate of the adenovirus E4orf6/E1B 55-kilodalton E3 ubiquitin ligase complex. J. Virol. 83:5329-5338.
    • (2009) J. Virol. , vol.83 , pp. 5329-5338
    • Dallaire, F.1    Blanchette, P.2    Groitl, P.3    Dobner, T.4    Branton, P.E.5
  • 23
    • 0037404513 scopus 로고    scopus 로고
    • Distinct roles of the adenovirus E4 ORF3 protein in viral DNA replication and inhibition of genome concatenation
    • Evans, J. D., and P. Hearing. 2003. Distinct roles of the adenovirus E4 ORF3 protein in viral DNA replication and inhibition of genome concatenation. J. Virol. 77:5295-5304.
    • (2003) J. Virol. , vol.77 , pp. 5295-5304
    • Evans, J.D.1    Hearing, P.2
  • 24
    • 18144401244 scopus 로고    scopus 로고
    • Relocalization of the Mre11-Rad50-Nbs1 complex by the adenovirus E4 ORF3 protein is required for viral replication
    • Evans, J. D., and P. Hearing. 2005. Relocalization of the Mre11-Rad50-Nbs1 complex by the adenovirus E4 ORF3 protein is required for viral replication. J. Virol. 79:6207-6215.
    • (2005) J. Virol. , vol.79 , pp. 6207-6215
    • Evans, J.D.1    Hearing, P.2
  • 25
    • 34447628045 scopus 로고    scopus 로고
    • Adenoviral E1B55K oncoprotein sequesters candidate leukemia suppressor sequence-specific single-stranded DNA-binding protein 2 into aggresomes
    • Fleisig, H. B., et al. 2007. Adenoviral E1B55K oncoprotein sequesters candidate leukemia suppressor sequence-specific single-stranded DNA-binding protein 2 into aggresomes. Oncogene 26:4797-4805.
    • (2007) Oncogene , vol.26 , pp. 4797-4805
    • Fleisig, H.B.1
  • 26
    • 0033621110 scopus 로고    scopus 로고
    • Role of the type 5 adenovirus gene encoding the early region 1B 55-kDa protein in pulmonary pathogenesis
    • Ginsberg, H. S., L. L. Moldawer, and G. A. Prince. 1999. Role of the type 5 adenovirus gene encoding the early region 1B 55-kDa protein in pulmonary pathogenesis. Proc. Natl. Acad. Sci. U. S. A. 96:10409-10411.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 10409-10411
    • Ginsberg, H.S.1    Moldawer, L.L.2    Prince, G.A.3
  • 27
    • 53649090109 scopus 로고    scopus 로고
    • DNA helicases Sgs1 and BLM promote DNA double-strand break resection
    • Gravel, S., J. R. Chapman, C. Magill, and S. P. Jackson. 2008. DNA helicases Sgs1 and BLM promote DNA double-strand break resection. Genes Dev. 22:2767-2772.
    • (2008) Genes Dev. , vol.22 , pp. 2767-2772
    • Gravel, S.1    Chapman, J.R.2    Magill, C.3    Jackson, S.P.4
  • 28
    • 0036720983 scopus 로고    scopus 로고
    • Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery
    • Harada, J. N., A. Shevchenko, A. Shevchenko, D. C. Pallas, and A. J. Berk. 2002. Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery. J. Virol. 76:9194-9206.
    • (2002) J. Virol. , vol.76 , pp. 9194-9206
    • Harada, J.N.1    Shevchenko, A.2    Shevchenko, A.3    Pallas, D.C.4    Berk, A.J.5
  • 29
    • 0032721540 scopus 로고    scopus 로고
    • PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1
    • Ishov, A. M., et al. 1999. PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1. J. Cell Biol. 147:221-234.
    • (1999) J. Cell Biol. , vol.147 , pp. 221-234
    • Ishov, A.M.1
  • 30
    • 70350504453 scopus 로고    scopus 로고
    • The DNA-damage response in human biology and disease
    • Jackson, S. P., and J. Bartek. 2009. The DNA-damage response in human biology and disease. Nature 461:1071-1078.
    • (2009) Nature , vol.461 , pp. 1071-1078
    • Jackson, S.P.1    Bartek, J.2
  • 31
    • 0034162770 scopus 로고    scopus 로고
    • Association of the Bloom syndrome protein with topoisomerase IIIalpha in somatic and meiotic cells
    • Johnson, F. B., et al. 2000. Association of the Bloom syndrome protein with topoisomerase IIIalpha in somatic and meiotic cells. Cancer Res. 60:1162-1167.
    • (2000) Cancer Res. , vol.60 , pp. 1162-1167
    • Johnson, F.B.1
  • 32
    • 33750980979 scopus 로고    scopus 로고
    • Human RECQ5beta helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication fork
    • Kanagaraj, R., N. Saydam, P. L. Garcia, L. Zheng, and P. Janscak. 2006. Human RECQ5beta helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication fork. Nucleic Acids Res. 34:5217-5231.
    • (2006) Nucleic Acids Res. , vol.34 , pp. 5217-5231
    • Kanagaraj, R.1    Saydam, N.2    Garcia, P.L.3    Zheng, L.4    Janscak, P.5
  • 33
    • 66149150524 scopus 로고    scopus 로고
    • Temporal regulation of the Mre11-Rad50-Nbs1 complex during adenovirus infection
    • Karen, K. A., P. J. Hoey, C. S. Young, and P. Hearing. 2009. Temporal regulation of the Mre11-Rad50-Nbs1 complex during adenovirus infection. J. Virol. 83:4565-4573.
    • (2009) J. Virol. , vol.83 , pp. 4565-4573
    • Karen, K.A.1    Hoey, P.J.2    Young, C.S.3    Hearing, P.4
  • 34
    • 0033046015 scopus 로고    scopus 로고
    • Evolution of the RECQ family of helicases: A drosophila homolog, Dmblm, is similar to the human bloom syndrome gene
    • Kusano, K., M. E. Berres, and W. R. Engels. 1999. Evolution of the RECQ family of helicases: a drosophila homolog, Dmblm, is similar to the human bloom syndrome gene. Genetics 151:1027-1039.
    • (1999) Genetics , vol.151 , pp. 1027-1039
    • Kusano, K.1    Berres, M.E.2    Engels, W.R.3
  • 35
    • 50149105185 scopus 로고    scopus 로고
    • Differential requirements of the C terminus of Nbs1 in suppressing adenovirus DNA replication and promoting concatemer formation
    • Lakdawala, S. S., et al. 2008. Differential requirements of the C terminus of Nbs1 in suppressing adenovirus DNA replication and promoting concatemer formation. J. Virol. 82:8362-8372.
    • (2008) J. Virol. , vol.82 , pp. 8362-8372
    • Lakdawala, S.S.1
  • 36
    • 77955841725 scopus 로고    scopus 로고
    • The MRN complex in double-strand break repair and telomere maintenance
    • Lamarche, B. J., N. I. Orazio, and M. D. Weitzman. 2010. The MRN complex in double-strand break repair and telomere maintenance. FEBS Lett. 584:3682-3695.
    • (2010) FEBS Lett. , vol.584 , pp. 3682-3695
    • Lamarche, B.J.1    Orazio, N.I.2    Weitzman, M.D.3
  • 37
    • 33847686708 scopus 로고    scopus 로고
    • Using or abusing: Viruses and the cellular DNA damage response
    • Lilley, C. E., R. A. Schwartz, and M. D. Weitzman. 2007. Using or abusing: viruses and the cellular DNA damage response. Trends Microbiol. 15:119-126.
    • (2007) Trends Microbiol. , vol.15 , pp. 119-126
    • Lilley, C.E.1    Schwartz, R.A.2    Weitzman, M.D.3
  • 38
    • 27644504904 scopus 로고    scopus 로고
    • Adenovirus exploits the cellular aggresome response to accelerate inactivation of the MRN complex
    • Liu, Y., A. Shevchenko, A. Shevchenko, and A. J. Berk. 2005. Adenovirus exploits the cellular aggresome response to accelerate inactivation of the MRN complex. J. Virol. 79:14004-14016.
    • (2005) J. Virol. , vol.79 , pp. 14004-14016
    • Liu, Y.1    Shevchenko, A.2    Shevchenko, A.3    Berk, A.J.4
  • 39
    • 41649088194 scopus 로고    scopus 로고
    • Nbs1-dependent binding of Mre11 to adenovirus E4 mutant viral DNA is important for inhibiting DNA replication
    • Mathew, S. S., and E. Bridge. 2008. Nbs1-dependent binding of Mre11 to adenovirus E4 mutant viral DNA is important for inhibiting DNA replication. Virology 374:11-22.
    • (2008) Virology , vol.374 , pp. 11-22
    • Mathew, S.S.1    Bridge, E.2
  • 40
    • 34547686371 scopus 로고    scopus 로고
    • The cellular Mre11 protein interferes with adenovirus E4 mutant DNA replication
    • Mathew, S. S., and E. Bridge. 2007. The cellular Mre11 protein interferes with adenovirus E4 mutant DNA replication. Virology 365:346-355.
    • (2007) Virology , vol.365 , pp. 346-355
    • Mathew, S.S.1    Bridge, E.2
  • 41
    • 68249116573 scopus 로고    scopus 로고
    • DNA end resection: Many nucleases make light work
    • (Amst.)
    • Mimitou, E. P., and L. S. Symington. 2009. DNA end resection: many nucleases make light work. DNA Repair (Amst.) 8:983-995.
    • (2009) DNA Repair , vol.8 , pp. 983-995
    • Mimitou, E.P.1    Symington, L.S.2
  • 42
    • 53649104599 scopus 로고    scopus 로고
    • Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
    • Mimitou, E. P., and L. S. Symington. 2008. Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing. Nature 455:770-774.
    • (2008) Nature , vol.455 , pp. 770-774
    • Mimitou, E.P.1    Symington, L.S.2
  • 44
    • 0032964641 scopus 로고    scopus 로고
    • The DNA helicase activity of BLM is necessary for the correction of the genomic instability of bloom syndrome cells
    • Neff, N. F., et al. 1999. The DNA helicase activity of BLM is necessary for the correction of the genomic instability of bloom syndrome cells. Mol. Biol. Cell 10:665-676.
    • (1999) Mol. Biol. Cell , vol.10 , pp. 665-676
    • Neff, N.F.1
  • 46
    • 0028092203 scopus 로고
    • Adenovirus replication and transcription sites are spatially separated in the nucleus of infected cells
    • Pombo, A., J. Ferreira, E. Bridge, and M. Carmo-Fonseca. 1994. Adenovirus replication and transcription sites are spatially separated in the nucleus of infected cells. EMBO J. 13:5075-5085. (Pubitemid 24341089)
    • (1994) EMBO Journal , vol.13 , Issue.21 , pp. 5075-5085
    • Pombo, A.1    Ferreira, J.2    Bridge, E.3    Carmo-Fonseca, M.4
  • 47
    • 0035577765 scopus 로고    scopus 로고
    • Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex
    • Querido, E., et al. 2001. Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex. Genes Dev. 15:3104-3117.
    • (2001) Genes Dev. , vol.15 , pp. 3104-3117
    • Querido, E.1
  • 48
    • 0030935013 scopus 로고    scopus 로고
    • Regulation of p53 levels by the E1B 55-kilodalton protein and E4orf6 in adenovirus-infected cells
    • Querido, E., et al. 1997. Regulation of p53 levels by the E1B 55-kilodalton protein and E4orf6 in adenovirus-infected cells. J. Virol. 71:3788-3798.
    • (1997) J. Virol. , vol.71 , pp. 3788-3798
    • Querido, E.1
  • 49
    • 0035158586 scopus 로고    scopus 로고
    • Identification of three functions of the adenovirus e4orf6 protein that mediate p53 degradation by the E4orf6-E1B55K complex
    • Querido, E., et al. 2001. Identification of three functions of the adenovirus e4orf6 protein that mediate p53 degradation by the E4orf6-E1B55K complex. J. Virol. 75:699-709.
    • (2001) J. Virol. , vol.75 , pp. 699-709
    • Querido, E.1
  • 50
    • 0031661779 scopus 로고    scopus 로고
    • Inactivation of p53 but not p73 by adenovirus type 5 E1B 55-kilodalton and E4 34-kilodalton oncoproteins
    • Roth, J., et al. 1998. Inactivation of p53 but not p73 by adenovirus type 5 E1B 55-kilodalton and E4 34-kilodalton oncoproteins. J. Virol. 72:8510-8516.
    • (1998) J. Virol. , vol.72 , pp. 8510-8516
    • Roth, J.1
  • 51
    • 50949088243 scopus 로고    scopus 로고
    • Distinct requirements of adenovirus E1b55K protein for degradation of cellular substrates
    • Schwartz, R. A., et al. 2008. Distinct requirements of adenovirus E1b55K protein for degradation of cellular substrates. J. Virol. 82:9043-9055.
    • (2008) J. Virol. , vol.82 , pp. 9043-9055
    • Schwartz, R.A.1
  • 52
    • 36348963101 scopus 로고    scopus 로고
    • The Mre11/Rad50/Nbs1 complex limits adeno-associated virus transduction and replication
    • Schwartz, R. A., et al. 2007. The Mre11/Rad50/Nbs1 complex limits adeno-associated virus transduction and replication. J. Virol. 81:12936-12945.
    • (2007) J. Virol. , vol.81 , pp. 12936-12945
    • Schwartz, R.A.1
  • 53
    • 33748744378 scopus 로고    scopus 로고
    • Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability
    • Sharma, S., K. M. Doherty, and R. M. Brosh, Jr. 2006. Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability. Biochem. J. 398:319-337.
    • (2006) Biochem. J. , vol.398 , pp. 319-337
    • Sharma, S.1    Doherty, K.M.2    Brosh Jr., R.M.3
  • 54
    • 0035050154 scopus 로고    scopus 로고
    • Analyses of single-amino-acid substitution mutants of adenovirus type 5 E1B-55K protein
    • Shen, Y., G. Kitzes, J. A. Nye, A. Fattaey, and T. Hermiston. 2001. Analyses of single-amino-acid substitution mutants of adenovirus type 5 E1B-55K protein. J. Virol. 75:4297-4307.
    • (2001) J. Virol. , vol.75 , pp. 4297-4307
    • Shen, Y.1    Kitzes, G.2    Nye, J.A.3    Fattaey, A.4    Hermiston, T.5
  • 55
    • 0032556920 scopus 로고    scopus 로고
    • The large E1B protein together with the E4orf6 protein target p53 for active degradation in adenovirus infected cells
    • Steegenga, W. T., N. Riteco, A. G. Jochemsen, F. J. Fallaux, and J. L. Bos. 1998. The large E1B protein together with the E4orf6 protein target p53 for active degradation in adenovirus infected cells. Oncogene 16:349-357.
    • (1998) Oncogene , vol.16 , pp. 349-357
    • Steegenga, W.T.1    Riteco, N.2    Jochemsen, A.G.3    Fallaux, F.J.4    Bos, J.L.5
  • 56
    • 0030994386 scopus 로고    scopus 로고
    • rqh1+, a fission yeast gene related to the Bloom's and Werner's syndrome genes, is required for reversible S phase arrest
    • Stewart, E., C. R. Chapman, F. Al-Khodairy, A. M. Carr, and T. Enoch. 1997. rqh1+, a fission yeast gene related to the Bloom's and Werner's syndrome genes, is required for reversible S phase arrest. EMBO J. 16:2682-2692.
    • (1997) EMBO J. , vol.16 , pp. 2682-2692
    • Stewart, E.1    Chapman, C.R.2    Al-Khodairy, F.3    Carr, A.M.4    Enoch, T.5
  • 57
    • 0037130170 scopus 로고    scopus 로고
    • Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex
    • Stracker, T. H., C. T. Carson, and M. D. Weitzman. 2002. Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex. Nature 418:348-352.
    • (2002) Nature , vol.418 , pp. 348-352
    • Stracker, T.H.1    Carson, C.T.2    Weitzman, M.D.3
  • 58
    • 18744362169 scopus 로고    scopus 로고
    • Serotype-specific reorganization of the Mre11 complex by adenoviral E4orf3 proteins
    • Stracker, T. H., et al. 2005. Serotype-specific reorganization of the Mre11 complex by adenoviral E4orf3 proteins. J. Virol. 79:6664-6673.
    • (2005) J. Virol. , vol.79 , pp. 6664-6673
    • Stracker, T.H.1
  • 59
    • 2442653990 scopus 로고    scopus 로고
    • Proteomics of herpes simplex virus replication compartments: Association of cellular DNA replication, repair, recombination, and chromatin remodeling proteins with ICP8
    • Taylor, T. J., and D. M. Knipe. 2004. Proteomics of herpes simplex virus replication compartments: association of cellular DNA replication, repair, recombination, and chromatin remodeling proteins with ICP8. J. Virol. 78: 5856-5866.
    • (2004) J. Virol. , vol.78 , pp. 5856-5866
    • Taylor, T.J.1    Knipe, D.M.2
  • 60
    • 19444379003 scopus 로고    scopus 로고
    • HMRE11 deficiency leads to microsatellite instability and defective DNA mismatch repair
    • Vo, A. T., et al. 2005. hMRE11 deficiency leads to microsatellite instability and defective DNA mismatch repair. EMBO Rep. 6:438-444.
    • (2005) EMBO Rep. , vol.6 , pp. 438-444
    • Vo, A.T.1
  • 61
    • 0034655991 scopus 로고    scopus 로고
    • BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures
    • Wang, Y., et al. 2000. BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev. 14:927-939.
    • (2000) Genes Dev. , vol.14 , pp. 927-939
    • Wang, Y.1
  • 62
    • 0029657781 scopus 로고    scopus 로고
    • SGS1, a homologue of the Bloom's and Werner's syndrome genes, is required for maintenance of genome stability in Saccharomyces cerevisiae
    • Watt, P. M., I. D. Hickson, R. H. Borts, and E. J. Louis. 1996. SGS1, a homologue of the Bloom's and Werner's syndrome genes, is required for maintenance of genome stability in Saccharomyces cerevisiae. Genetics 144: 935-945.
    • (1996) Genetics , vol.144 , pp. 935-945
    • Watt, P.M.1    Hickson, I.D.2    Borts, R.H.3    Louis, E.J.4
  • 63
    • 0028057972 scopus 로고
    • Deletion of the E4 region of the genome produces adenovirus DNA concatemers
    • Weiden, M. D., and H. S. Ginsberg. 1994. Deletion of the E4 region of the genome produces adenovirus DNA concatemers. Proc. Natl. Acad. Sci. U. S. A. 91:153-157.
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 153-157
    • Weiden, M.D.1    Ginsberg, H.S.2
  • 64
    • 0022624195 scopus 로고
    • Adenoviral early region 4 is required for efficient viral DNA replication and for late gene expression
    • Weinberg, D. H., and G. Ketner. 1986. Adenoviral early region 4 is required for efficient viral DNA replication and for late gene expression. J. Virol. 57:833-838.
    • (1986) J. Virol. , vol.57 , pp. 833-838
    • Weinberg, D.H.1    Ketner, G.2
  • 65
    • 77957951602 scopus 로고    scopus 로고
    • Genomes in conflict: Maintaining genome integrity during virus infection
    • Weitzman, M. D., C. E. Lilley, and M. S. Chaurushiya. 2010. Genomes in conflict: maintaining genome integrity during virus infection. Annu. Rev. Microbiol. 64:61-81.
    • (2010) Annu. Rev. Microbiol. , vol.64 , pp. 61-81
    • Weitzman, M.D.1    Lilley, C.E.2    Chaurushiya, M.S.3
  • 66
    • 0033989602 scopus 로고    scopus 로고
    • E1B 55-kilodalton oncoproteins of adenovirus types 5 and 12 inactivate and relocalize p53, but not p51 or p73, and cooperate with E4orf6 proteins to destabilize p53
    • Wienzek, S., J. Roth, and M. Dobbelstein. 2000. E1B 55-kilodalton oncoproteins of adenovirus types 5 and 12 inactivate and relocalize p53, but not p51 or p73, and cooperate with E4orf6 proteins to destabilize p53. J. Virol. 74:193-202.
    • (2000) J. Virol. , vol.74 , pp. 193-202
    • Wienzek, S.1    Roth, J.2    Dobbelstein, M.3
  • 67
    • 4644296028 scopus 로고    scopus 로고
    • Recruitment of cellular recombination and repair proteins to sites of herpes simplex virus type 1 DNA replication is dependent on the composition of viral proteins within prereplicative sites and correlates with the induction of the DNA damage response
    • Wilkinson, D. E., and S. K. Weller. 2004. Recruitment of cellular recombination and repair proteins to sites of herpes simplex virus type 1 DNA replication is dependent on the composition of viral proteins within prereplicative sites and correlates with the induction of the DNA damage response. J. Virol. 78:4783-4796.
    • (2004) J. Virol. , vol.78 , pp. 4783-4796
    • Wilkinson, D.E.1    Weller, S.K.2
  • 68
    • 33846118836 scopus 로고    scopus 로고
    • Adenovirus ubiquitin-protein ligase stimulates viral late mRNA nuclear export
    • Woo, J. L., and A. J. Berk. 2007. Adenovirus ubiquitin-protein ligase stimulates viral late mRNA nuclear export. J. Virol. 81:575-587.
    • (2007) J. Virol. , vol.81 , pp. 575-587
    • Woo, J.L.1    Berk, A.J.2
  • 69
    • 0034737641 scopus 로고    scopus 로고
    • The Bloom's syndrome gene product interacts with topoisomerase III
    • Wu, L., et al. 2000. The Bloom's syndrome gene product interacts with topoisomerase III. J. Biol. Chem. 275:9636-9644.
    • (2000) J. Biol. Chem. , vol.275 , pp. 9636-9644
    • Wu, L.1
  • 70
    • 0347987856 scopus 로고    scopus 로고
    • The Bloom's syndrome helicase suppresses crossing over during homologous recombination
    • Wu, L., and I. D. Hickson. 2003. The Bloom's syndrome helicase suppresses crossing over during homologous recombination. Nature 426:870-874.
    • (2003) Nature , vol.426 , pp. 870-874
    • Wu, L.1    Hickson, I.D.2
  • 72
    • 43949088506 scopus 로고    scopus 로고
    • Ataxia telangiectasia-mutated damage-signaling kinase-and proteasome-dependent destruction of Mre11-Rad50-Nbs1 subunits in simian virus 40-infected primate cells
    • Zhao, X., et al. 2008. Ataxia telangiectasia-mutated damage-signaling kinase-and proteasome-dependent destruction of Mre11-Rad50-Nbs1 subunits in simian virus 40-infected primate cells. J. Virol. 82:5316-5328.
    • (2008) J. Virol. , vol.82 , pp. 5316-5328
    • Zhao, X.1
  • 73
    • 0033598931 scopus 로고    scopus 로고
    • A role for PML and the nuclear body in genomic stability
    • Zhong, S., et al. 1999. A role for PML and the nuclear body in genomic stability. Oncogene 18:7941-7947.
    • (1999) Oncogene , vol.18 , pp. 7941-7947
    • Zhong, S.1


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