A subunit vaccine based on biodegradable microspheres carrying rHsp65 protein and KLK protects BALB/c mice against tuberculosis infection

Human Vaccines

Volumn 6, Issue 12, 2010, Pages 1047-1053

  Dos Santos, Sandra Aparecida ^a   Zárate Bladés, Carlos Rodrigo ^a   De Sá Galetti, Fábio Cícero ^a   Brandão, Izaíra Tincani ^a   Masson, Ana Paula ^a   Soares, Edson Garcia ^a   Araújo, Ana Paula Ulian ^a   Silva, Celio Lopes ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Adjuvant; Heat shock protein; Immunization; Microspheres; Tuberculosis

Indexed keywords

BACTERIAL VACCINE; CPG 1668; CPG OLIGODEOXYNUCLEOTIDE; DNA VACCINE; GAMMA INTERFERON; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 10; LYSYLLEUCYLLYSINE; MICROSPHERE; POLYGLACTIN; RECOMBINANT HEAT SHOCK PROTEIN 65; RECOMBINANT HEAT SHOCK PROTEIN 65 CPG 1668; RECOMBINANT HEAT SHOCK PROTEIN 65 PLUS LYSYLLEUCYLLYSINE; RECOMBINANT VACCINE; SUBUNIT VACCINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL STRAIN; CELLULAR IMMUNITY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; HUMORAL IMMUNITY; LUNG INJURY; LUNG PARENCHYMA; MICROENCAPSULATION; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHAGOCYTE; PHAGOCYTOSIS; TUBERCULOSIS;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; BACTERIAL PROTEINS; CHAPERONIN 60; DISEASE MODELS, ANIMAL; DRUG DELIVERY SYSTEMS; FEMALE; LACTIC ACID; LUNG; MICE; MICE, INBRED BALB C; MICROSPHERES; MYCOBACTERIUM TUBERCULOSIS; POLYGLYCOLIC ACID; TUBERCULOSIS; TUBERCULOSIS VACCINES; VACCINES, SUBUNIT; VACCINES, SYNTHETIC;

EID: 78751652948     PISSN: 15548600     EISSN: 15548619     Source Type: Journal    
DOI: 10.4161/hv.6.12.13350     Document Type: Article

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