Synthesis and structure-analgesic activity relationships of a novel series of monospirocyclopiperazinium salts (MSPZ)

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 3, 2011, Pages 940-943

  Lin, Song Wen ^a   Sun, Qi ^a   Ge, Ze Mei ^a   Wang, Xin ^a   Ye, Jia ^a   Li, Run Tao ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

7 Nicotinic acetylcholine receptors; M4 muscarinic acetylcholine receptors; Monospirocyclopiperazinium salts; Peripherally acting analgesic activity; Structure activity relationships

Indexed keywords

MONOSPIROCYCLOPIPERAZINIUM DERIVATIVE; PIPERAZINE DERIVATIVE; SPIRO COMPOUND; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ARTICLE; DRUG DESIGN; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION;

ANALGESICS; ANIMALS; MICE; PIPERAZINES; SALTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 78751644718     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.12.052     Document Type: Article

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