Structure-affinity relationships of a unique nicotinic ligand: N1-dimethyl-N4-phenylpiperazinium iodide (DMPP)

Journal of Medicinal Chemistry

Volumn 44, Issue 23, 2001, Pages 3946-3955

  Romanelli, M N ^a   Manetti, D ^a   Scapecchi, S ^a   Borea, P A ^b   Dei, S ^a   Bartolini, A ^a   Ghelardini, C ^a   Gualtieri, F ^a   Guandalini, L ^a   Varani, K ^b  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1 (3' AMINOPHENYL) 4 METHYLPIPERAZINE; 1 (3' PYRIDYL)PIPERAZINE; N 1 DIMETHYL N 4 PHENYLPIPERAZINIUM IODIDE; NICOTINIC AGENT; NICOTINIC RECEPTOR; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL TISSUE; ARTICLE; DRUG RECEPTOR BINDING; DRUG STRUCTURE; MOUSE; NERVE DEGENERATION; NONHUMAN; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

ANALGESICS; ANIMALS; CEREBRAL CORTEX; DIMETHYLPHENYLPIPERAZINIUM IODIDE; LIGANDS; MALE; MICE; NICOTINIC AGONISTS; PAIN MEASUREMENT; PIPERIDINES; PYRIDINES; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, NICOTINIC; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035829401     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010901y     Document Type: Article

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