ECM1 controls TH2 cell egress from lymph nodes through re-expression of S1P1

Nature Immunology

Volumn 12, Issue 2, 2011, Pages 178-185

  Li, Zhenhu ^a   Zhang, Yuan ^a   Liu, Zhiduo ^a   Wu, Xiaodong ^a   Zheng, Yuhan ^a   Tao, Zhiyun ^a   Mao, Kairui ^a   Wang, Jie ^a   Lin, Guomei ^a   Tian, Lin ^a   Ji, Yongyong ^a   Qin, Meiling ^a   Sun, Shuhui ^b   Zhu, Xueliang ^a   Sun, Bing ^a,c  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^b FUDAN UNIVERSITY   (China)

^c INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

EXTRACELLULAR MATRIX PROTEIN 1; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; KRUPPEL LIKE FACTOR; KRUPPEL LIKE FACTOR 2; PROTEIN; PROTEIN S1P1; SCLEROPROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; LYMPH NODE; LYMPHOCYTE MIGRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TH2 CELL;

ADOPTIVE TRANSFER; ANIMALS; CELL DIFFERENTIATION; CELL MOVEMENT; CELLS, CULTURED; DISEASE MODELS, ANIMAL; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION REGULATION; HUMANS; HYPERSENSITIVITY; LYMPH NODES; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; RECEPTORS, LYMPHOCYTE HOMING; SIGNAL TRANSDUCTION; TH2 CELLS; TRANSGENES;

EID: 78751621721     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.1983     Document Type: Article

References (36)

1. Scharton, T.M. & Scott, P. Natural killer cells are a source of interferon gamma that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice. J. Exp. Med. 178, 567-577 (1993).
2. Mosmann, T.R. & Coffman, R.L. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7, 145-173 (1989).
3. Weaver, C.T., Harrington, L.E., Mangan, P.R., Gavrieli, M. & Murphy, K.M. Th17: an effector CD4 T cell lineage with regulatory T cell ties. Immunity 24, 677-688 (2006).
4. Zhu, J. & Paul, W.E. CD4 T cells: fates, functions, and faults. Blood 112, 1557-1569 (2008).
5. Dong, C. TH17 cells in development: an updated view of their molecular identity and genetic programming. Nature Rev. Immunol. 8, 337-348 (2008).
6. Murphy, K.M. & Reiner, S.L. The lineage decisions of helper T cells. Nature Rev. Immunol. 2, 933-944 (2002).
7. Rosen, H. et al. Modulating tone: the overture of S1P receptor immunotherapeutics. Immunol. Rev. 223, 221-235 (2008).
8. Schwab, S.R. & Cyster, J.G. Finding a way out: lymphocyte egress from lymphoid organs. Nat. Immunol. 8, 1295-1301 (2007).
9. Rivera, J., Proia, R.L. & Olivera, A. The alliance of sphingosine-1-phosphate and its receptors in immunity. Nature Rev. Immunol. 8, 753-763 (2008).
10. Graeler, M. & Goetzl, E.J. Activation-regulated expression and chemotactic function of sphingosine 1-phosphate receptors in mouse splenic T cells. FASEB J. 16, 1874-1878 (2002).
11. Mandala, S. et al. Alteration of lymphocyte traffcking by sphingosine-1-phosphate receptor agonists. Science 296, 346-349 (2002).
12. Brinkmann, V. et al. The immune modulator FTY720 targets sphingosine 1-phosphate receptors. J. Biol. Chem. 277, 21453-21457 (2002).
13. Matloubian, M. et al. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature 427, 355-360 (2004).
14. Allende, M.L., Dreier, J.L., Mandala, S. & Proia, R.L. Expression of the sphingosine 1-phosphate receptor, S1P1, on T-cells controls thymic emigration. J. Biol. Chem. 279, 15396-15401 (2004).
15. Chi, H. & Flavell, R.A. Cutting edge: regulation of T cell traffcking and primary immune responses by sphingosine 1-phosphate receptor 1. J. Immunol. 174, 2485-2488 (2005).
16. Gräler, M.H., Huang, M.C., Watson, S. & Goetzl, E.J. Immunological effects of transgenic constitutive expression of the type 1 sphingosine 1-phosphate receptor by mouse lymphocytes. J. Immunol. 174, 1997-2003 (2005).
17. Cyster, J.G. Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs. Annu. Rev. Immunol. 23, 127-159 (2005).
18. Bhalerao, J., Tylzanowski, P., Filie, J.D., Kozak, C.A. & Merregaert, J. Molecular cloning, characterization, and genetic mapping of the cDNA coding for a novel secretory protein of mouse. Demonstration of alternative splicing in skin and cartilage. J. Biol. Chem. 270, 16385-16394 (1995).
19. Mongiat, M. et al. Perlecan protein core interacts with extracellular matrix protein 1 (ECM1), a glycoprotein involved in bone formation and angiogenesis. J. Biol. Chem. 278, 17491-17499 (2003).
20. Hamada, T. Lipoid proteinosis. Clin. Exp. Dermatol. 27, 624-629 (2002).
21. Han, Z. et al. Extracellular matrix protein 1 (ECM1) has angiogenic properties and is expressed by breast tumor cells. FASEB J. 15, 988-994 (2001).
22. Wang, L. et al. Extracellular matrix protein 1 (ECM1) is over-expressed in malignant epithelial tumors. Cancer Lett. 200, 57-67 (2003).
23. Liu, Z. et al. Dec2 promotes Th2 cell differentiation by enhancing IL-2R signaling. J. Immunol. 183, 6320-6329 (2009).
24. Luger, D. et al. Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category. J. Exp. Med. 205, 799-810 (2008).
25. Carlson, C.M. et al. Kruppel-like factor 2 regulates thymocyte and T-cell migration. Nature 442, 299-302 (2006).
26. Kerdiles, Y.M. et al. Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor. Nat. Immunol. 10, 176-184 (2009).
27. Sinclair, L.V. et al. Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte traffcking. Nat. Immunol. 9, 513-521 (2008).
28. Leonard, W.J. & O'Shea, J.J. Jaks and STATs: biological implications. Annu. Rev. Immunol. 16, 293-322 (1998).
29. Miller, J.D., Stevens, E.T., Smith, D.R., Wight, T.N. & Wrenshall, L.E. Perlecan: a major IL-2-binding proteoglycan in murine spleen. Immunol. Cell Biol. 86, 192-199 (2008).
30. Kuznetsova, S.A. & Roberts, D.D. Functional regulation of T lymphocytes by modulatory extracellular matrix proteins. Int. J. Biochem. Cell Biol. 36, 1126-1134 (2004).
31. Medoff, B.D., Thomas, S.Y. & Luster, A.D. T cell traffcking in allergic asthma: the ins and outs. Annu. Rev. Immunol. 26, 205-232 (2008).
32. Dang, X., Raffer, N.A. & Ley, K. Transcriptional regulation of mouse L-selectin. Biochim. Biophys. Acta 1789, 146-152 (2009).
33. Le Gros, G., Ben-Sasson, S.Z., Seder, R., Finkelman, F.D. & Paul, W.E. Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells. J. Exp. Med. 172, 921-929 (1990).
34. Hou, W. et al. Pertussis toxin enhances Th1 responses by stimulation of dendritic cells. J. Immunol. 170, 1728-1736 (2003).
35. Wang, Y. et al. Trichosanthin functions as Th2-type adjuvant in induction of allergic airway infammation. Cell Res. 19, 962-972 (2009).
36. Wu, X. et al. Novel function of IFN-gamma: negative regulation of dendritic cell migration and T cell priming. J. Immunol. 177, 934-943 (2006).