Synthesis of new amonafide analogues via coupling reaction and their cytotoxic evaluation and DNA-binding studies

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 2, 2009, Pages 804-810

  Xie, Lijuan ^a   Xu, Yufang ^b   Wang, Fang ^b   Liu, Jianwen ^b   Qian, Xuhong ^a,b   Cui, Jingnan ^a  

^a DALIAN UNIVERSITY OF TECHNOLOGY   (China)

^b EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Amonafide analogues; Coupling reaction; DNA binding

Indexed keywords

5 (4' METHYLPIPERAZINE) 2 [2 (DIMETHYLAMINO)ETHYL] 1H BENZO[DE]ISOQUINOLINE 1,3(2H) DIONE; 5 (DIMETHYLAMINOPROPYLAMINO) 2 [2 (DIMETHYLAMINO)ETHYL] 1H BENZO[DE]ISOQUINOLINE 1,3(2H) DIONE; AMONAFIDE; AMONAFIDE DERIVATIVE; COPPER DERIVATIVE; NAPHTHALIMIDE DERIVATIVE; PROLINE; UNCLASSIFIED DRUG;

AMINATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CATALYSIS; CHEMICAL REACTION; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; DRUG STRUCTURE; HUMAN; HUMAN CELL;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DNA; HUMANS; NAPHTHALENES; NAPHTHALIMIDES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 58549097070     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.11.053     Document Type: Article

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