Association of thromboxane A2 receptor (TBXA2R) gene polymorphism in patients with aspirin-intolerant acute urticaria

Clinical and Experimental Allergy

Volumn 41, Issue 2, 2011, Pages 179-185

  Palikhe, N S ^a   Kim, S H ^a   Lee, H Y ^a   Kim, J H ^a   Ye, Y M ^a   Park, H S ^a  

^a Ajou University School of Medicine   (South Korea)

Author keywords

ASA intolerant acute urticaria; Polymorphism; Thromboxane A2; Thromboxane A2 receptor gene

Indexed keywords

ACETYLSALICYLIC ACID; LUCIFERASE; THROMBOXANE A2 RECEPTOR;

ALLELE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVITY; FEMALE; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MAST CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROVOCATION TEST; SINGLE NUCLEOTIDE POLYMORPHISM; URTICARIA;

ACUTE DISEASE; ADULT; ALLELES; ASPIRIN; FEMALE; GENOTYPE; HUMANS; MALE; PHENOTYPE; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, THROMBOXANE A2, PROSTAGLANDIN H2; URTICARIA;

EID: 78651451429     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2010.03642.x     Document Type: Article

References (32)

1. Grattan CE. Aspirin sensitivity and urticaria. Clin Exp Dermatol 2003; 28:123-7.
2. Kim SH, Park HS. Genetic markers for differentiating aspirin-hypersensitivity. Yonsei Med J 2006; 47:15-21.
3. Kim SH, Kang YM, Kim SH et al. Histamine N-methyltransferase 939A>G polymorphism affects mRNA stability in patients with acetylsalicylic acid-intolerant chronic urticaria. Allergy 2009; 64:213-21.
4. Bae JS, Kim SH, Ye YM et al. Significant association of FcepsilonRIalpha promoter polymorphisms with aspirin-intolerant chronic urticaria. J Allergy Clin Immunol 2007; 119:449-56.
5. Powell RJ, Du Toit GL, Siddique N et al. Basic guidelines for the management of chronic urticaria and angio-oedema. Clin Exp Allergy 2007; 37:631-50.
6. Choi SJ, Ye YM, Hur GY, Shin SY, Han JH, Park HS. Neutrophil activation in patients with ASA-induced urticaria. J Clin Immunol 2008; 28:244-9.
7. Mastalerz L, Setkowicz M, Sanak M, Szczeklik A. Hypersensitivity to aspirin: common eicosanoid alterations in urticaria and asthma. J Allergy Clin Immunol 2004; 113:771-5.
8. Zembowicz A, Mastalerz L, Setkowicz M, Radziszewski W, Szczeklik A. Safety of cyclooxygenase 2 inhibitors and increased leukotriene synthesis in chronic idiopathic urticaria with sensitivity to nonsteroidal anti-inflammatory drugs. Arch Dermatol 2003; 139:1577-82.
9. Kim SH, Oh JM, Kim YS et al. Cysteinyl leukotriene receptor 1 polymorphism is associated with aspirin-intolerant asthma in males. Clin Exp Allergy 2006; 36:433-9.
10. O'Byrne PM, Fuller RW. The role of thromboxane A2 in the pathogenesis of airway hyperresponsiveness. Eur Respir J 1989; 2:782-6.
11. Devillier P, Bessard G. Thromboxane A2 and related prostaglandins in airways. Fundam Clin Pharmacol 1997; 11:2-18.
12. Taylor IK, Ward PS, O'Shaughnessy KM et al. Thromboxane A2 biosynthesis in acute asthma and after antigen challenge. Am Rev Respir Dis 1991; 143:119-25.
13. Capra V, Habib A, Accomazzo MR et al. Thromboxane prostanoid receptor in human airway smooth muscle cells: a relevant role in proliferation. Eur J Pharmacol 2003; 474:149-59.
14. Preston FE, Whipps S, Jackson CA, French AJ, Wyld PJ, Stoddard CJ. Inhibition of prostacyclin and platelet thromboxane A2 after low-dose aspirin. N Engl J Med 1981; 304:76-9.
15. Unoki M, Furuta S, Onouchi Y et al. Association studies of 33 single nucleotide polymorphisms (SNPs) in 29 candidate genes for bronchial asthma: positive association a T924C polymorphism in the thromboxane A2 receptor gene. Hum Genet 2000; 106:440-6.
16. Leung TF, Tang NL, Lam CW, Li AM, Chan IH, Ha G. Thromboxane A2 receptor gene polymorphism is associated with the serum concentration of cat-specific immunoglobulin E as well as the development and severity of asthma in Chinese children. Pediatr Allergy Immunol 2002; 13:10-7.
17. Tanaka K, Roberts MH, Yamamoto N et al. Genetic variants of the receptors for thromboxane A2 and IL-4 in atopic dermatitis. Biochem Biophys Res Commun 2002; 292:776-80.
18. Shin HD, Park BL, Jung JH et al. Association of thromboxane A2 receptor (TBXA2R) with atopy and asthma. J Allergy Clin Immunol 2003; 112:454-7.
19. Nagase T, Ishii S, Katayama H, Fukuchi Y, Ouchi Y, Shimizu T. Airway responsiveness in transgenic mice overexpressing platelet-activating factor receptor. Roles of thromboxanes and leukotrienes. Am J Respir Crit Care Med 1997; 156:1621-7.
20. Shi H, Yokoyama A, Kohno N et al. Effect of thromboxane A2 inhibitors on allergic pulmonary inflammation in mice. Eur Respir J 1998; 11:624-9.
21. Rolin S, Masereel B, Dogne JM. Prostanoids as pharmacological targets in COPD and asthma. Eur J Pharmacol 2006; 533:89-100.
22. Kim JH, Lee SY, Kim HB et al. TBXA2R gene polymorphism and responsiveness to leukotriene receptor antagonist in children with asthma. Clin Exp Allergy 2008; 38:51-9.
23. Tornhamre S, Edenius C, Lindgren JA. Receptor-mediated regulation of leukotriene c4 synthase activity in human platelets. Eur J Biochem 1995; 234:513-20.
24. Tornhamre S, Ehnhage A, Kolbeck KG, Edenius C, Lindgren JA. Uncoupled regulation of leukotriene c4 synthase in platelets from aspirin-intolerant asthmatics and healthy volunteers after aspirin treatment. Clin Exp Allergy 2002; 32:1566-73.
25. Kim SH, Choi JH, Park HS et al. Association of thromboxane A2 receptor gene polymorphism with the phenotype of acetyl salicylic acid-intolerant asthma. Clin Exp Allergy 2005; 35:585-90.
26. Palikhe NS, Kim SH, Cho BY, Ye YM, Choi GS, Park HS. Genetic variability of CRTH2 polymorphism increases eotaxin-2 in patients with aspirin-exacerbated respiratory disease. Allergy 2009; 65:338-46.
27. Macchia L, Hamberg M, Kumlin M, Butterfield JH, Haeggstrom JZ. Arachidonic acid metabolism in the human mast cell line HMC-1: 5-lipoxygenase gene expression and biosynthesis of thromboxane. Biochim Biophys Acta 1995; 1257:58-74.
28. Celik G, Bavbek S, Misirligil Z, Melli M. Release of cysteinyl leukotrienes with aspirin stimulation and the effect of prostaglandin E2 on this release from peripheral blood leucocytes in aspirin-induced asthmatic patients. Clin Exp Allergy 2001; 31:1615-22.
29. Asero R. Leukotriene receptor antagonists may prevent NSAID-induced exacerbations in patients with chronic urticaria. Ann Allergy Asthma Immunol 2000; 85:156-7.
30. Pérez C, Sánchez-Borges M, Capriles E. Pretreatment with montelukast blocks NSAID-induced urticaria and angioedema. J Allergy Clin Immunol 2001; 108:1060-1.
31. 2 receptor expression via activation of MAPK ERK1/2, p38/NF-κB pathways. J Vasc Res 2009; 46:162-74.
32. Sharrocks AD. Complexities in ETS-domain transcription factor function and regulation: lessons from the TCF (ternary complex factor) subfamily. The Colworth Medal Lecture. Biochem Soc Trans 2002; 30:1-9.