Association studies of 33 single nucleotide polymorphisms (SNPs) in 29 candidate genes for bronchial asthma: Positive association of a T924C polymorphism in the thromboxane A2 receptor gene

Human Genetics

Volumn 106, Issue 4, 2000, Pages 440-446

  Unoki, Motoko ^a   Furuta, Sachiyo ^a   Onouchi, Yoshihiro ^a   Watanabe, Otsu ^a   Doi, Satoru ^b   Fujiwara, Hiroshi ^b   Miyatake, Akihiko ^c   Fujita, Kimie ^d   Tamari, Mayumi ^a   Nakamura, Yusuke ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b OSAKA PREFECTURAL MEDICAL CENTER FOR RESPIRATORY AND ALLERGIC DISEASES   (Japan)

^c Miyatake Asthma Clinic   (Japan)

^d UNIVERSITY OF SHIGA PREFECTURE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

THROMBOXANE A2 RECEPTOR;

ARTICLE; ASTHMA; CLINICAL ARTICLE; CONTROLLED STUDY; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; PATHOGENESIS; PRIORITY JOURNAL;

EID: 0034013702     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004390000267     Document Type: Article

References (19)

1. Ashkenazi A, Dixit VM (1998) Death receptors: signaling and modulation. Science 281:1305-1308
2. Cargill M, Altshler D, Ireland J, Sklar P, Ardlie K, Patil N, Lane CR, Lim EP, Kalyanaraman N, Nemesh J, Ziaugra L, Frieland L, Rolfe A, Warrington J, Lipshutz R, Daley GD, Lander ES (1999) Characterization of single-nucleotide polymorphisms in coding regions of human genes. Nat Genet 22:231-238
3. Deichmann KA, Schmidt A, Heinzmann A, Kruse S, Forster J, Kuehr J (1999) Association studies on beta2-adrenoceptor polymorphisms and enhanced IgE responsiveness in an atopic population. Clin Exp Allergy 29:794-799
4. Drazen JM, Israel E, O'Byme PM (1999a) Treatment of asthma with drugs modifying the leukotriene pathway. N Engl J Med 340:197-206
5. Drazen JM, Yandava CN, Dube L, Szczerback N, Hippensteel R, Pillari A, Israel E, Schork N, Silverman ES, Katz DA, Drajesk J (1999b) Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment. Nat Genet 22:168-170
6. Fitch WM (1967) Evidence suggesting a non-random character to nucleotide replacements in naturally occurring mutations. J Mol Biol 26:499-507
7. Hirata T, Kakizuka A, Ushikubi F, Fuse I, Okuma M, Narumiya S (1994) Arg60 to Leu mutation of the human thromboxane A2 receptor in a dominantly inherited bleeding disorder. J Clin Invest 94:1662-1667
8. Hijazi Z, Haider MZ, Khan MR, Al-Dowaisan AA (1998) High frequency of IgE receptor Fc epsilon RI beta variant (Leu181/ Leu183) in Kuwaiti Arabs and its association with asthma. Clin Genet 53:149-152
9. Hopes E, McDougall C, Christie G, Dewar J, Wheatley A, Hall IP, Helms PJ (1998) Association of glutamine 27 polymorphism of beta 2 adrenoceptor with reported childhood asthma: population based study. BMJ 316:664
10. Ishizawa M, Shibasaki M, Yokouchi Y, Noguchi E, Arinami T, Yamakawa-Kobayashi K, Matsui A, Hamaguchi H (1999) No association between atopic asthma and a coding variant of Fc epsilon R1 beta in a Japanese population. J Hum Genet 44:308-311
11. Noguchi E, Shibasaki M, Arinami T, Takeda K, Yokouchi Y, Kawashima T, Yanagi H, Matsui A, Hamaguchi H (1998) Association of asthma and the interleukin-4 promoter gene in Japanese. Clin Exp Allergy 28:449-453
12. Noguchi E, Shibasaki M, Arinami T, Takeda K, Yokouchi Y, Kobayashi K, Imoto N, Nakahara S, Matsui A, Hamaguchi H (1999) No association between atopy/asthma and the ILe50Val polymorphism of IL-4 receptor. Am J Respir Crit Care Med 160:342-345
13. Nusing RM, Hirata M, Kakizuka A, Eki T, Ozawa K, Narumiya S (1993) Characterization and chromosomal mapping of the human thromboxane A2 receptor gene. J Biol Chem 268:25253-25259
14. O'Byrne PM, Israel E, Drazen JM (1997) Antileukotrienes in the treatment of asthma. Ann Intern Med 127:472-480
15. Richard I, Beckmann JS (1995) How neutral are synonymous codon mutations? Nat Genet 10:259
16. Siffert W, Rosskopf D, Siffert G, Busch S, Moritz A, Erbel R, Sharma AM, Ritz E, Wichmann HE, Jakobs KH, Horsthemke B (1998) Association of a human G-protein beta3 subunit variant with hypertension. Nat Genet 18:45-48
17. Vogel F (1972) Non-randomness of base replacement in point mutation. J Mol Evol 1:334-367
18. Vogel F, Kopun M (1977) Higher frequencies of transitions among point mutations. J Mol Evol 9:159-180
19. Walczak H, Degli-Esposti MA, Johnson RS, Smolak PJ, Waugh JY, Boiani N, Timour MS, Gerhart MJ, Schooley KA, Smith CA, Goodwin RG, Rauch CT (1997) TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL. EMBO J 16:5386-5397