-
1
-
-
33846211453
-
Structure-Based Organic Synthesis of Drug Prototypes: A Personal Odyssey
-
Hanessian, S. Structure-Based Organic Synthesis of Drug Prototypes: A Personal Odyssey Chem. Med. Chem. 2006, 1, 1300-1330
-
(2006)
Chem. Med. Chem.
, vol.1
, pp. 1300-1330
-
-
Hanessian, S.1
-
2
-
-
34247109045
-
Natural Products as Sources of New Drugs over the Last 25 Years
-
Newman, D. J.; Cragg, G. M. Natural Products as Sources of New Drugs over the Last 25 Years J. Nat. Prod. 2007, 70, 461-477
-
(2007)
J. Nat. Prod.
, vol.70
, pp. 461-477
-
-
Newman, D.J.1
Cragg, G.M.2
-
3
-
-
58149358949
-
Organic chemistry: Molecular diversity by design
-
Schreiber, S. L. Organic chemistry: Molecular diversity by design Nature 2009, 457, 153-154
-
(2009)
Nature
, vol.457
, pp. 153-154
-
-
Schreiber, S.L.1
-
4
-
-
0141427680
-
Natural product hybrids as new leads for drug discovery
-
Tietze, L. F.; Bell, H. P.; Chandrasekhar, S. Natural product hybrids as new leads for drug discovery Angew. Chem., Int. Ed. 2003, 42, 3996-4028
-
(2003)
Angew. Chem., Int. Ed.
, vol.42
, pp. 3996-4028
-
-
Tietze, L.F.1
Bell, H.P.2
Chandrasekhar, S.3
-
5
-
-
0035139990
-
Antitubercular activity of triterpenoids from Lippia turbinata
-
Wachter, G. A.; Valcic, S.; Franzblau, S. G.; Suarez, E.; Timmermann, B. N. Antitubercular activity of triterpenoids from Lippia turbinata J. Nat. Prod. 2001, 64, 37-41
-
(2001)
J. Nat. Prod.
, vol.64
, pp. 37-41
-
-
Wachter, G.A.1
Valcic, S.2
Franzblau, S.G.3
Suarez, E.4
Timmermann, B.N.5
-
6
-
-
0028012837
-
Total synthesis of taxol
-
Nicolaou, K. C.; Yang, Z.; Liu, J. J.; Ueno, H.; Nantermet, P. G.; Guy, R. K.; Claiborne, C. F.; Renaud, J. Total synthesis of taxol Nature 1994, 367, 630-634
-
(1994)
Nature
, vol.367
, pp. 630-634
-
-
Nicolaou, K.C.1
Yang, Z.2
Liu, J.J.3
Ueno, H.4
Nantermet, P.G.5
Guy, R.K.6
Claiborne, C.F.7
Renaud, J.8
-
7
-
-
33748226949
-
Chemistry and Biology of Taxol
-
Nicolaou, K. C.; Dai, W. M.; Guy, R. K. Chemistry and Biology of Taxol Angew. Chem., Int. Ed. Engl. 1994, 33, 15-44
-
(1994)
Angew. Chem., Int. Ed. Engl.
, vol.33
, pp. 15-44
-
-
Nicolaou, K.C.1
Dai, W.M.2
Guy, R.K.3
-
8
-
-
0034678033
-
Target-Oriented and Diversity-Oriented Organic Synthesis in Drug Discovery
-
Schreiber, S. L. Target-Oriented and Diversity-Oriented Organic Synthesis in Drug Discovery Science 2000, 287, 1964-1969
-
(2000)
Science
, vol.287
, pp. 1964-1969
-
-
Schreiber, S.L.1
-
9
-
-
48149108752
-
Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries
-
Cordier, C.; Morton, D.; Murrison, S.; Nelson, A.; O′Leary-Steele, C. Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries Nat. Prod. Rep. 2008, 25, 719-737
-
(2008)
Nat. Prod. Rep.
, vol.25
, pp. 719-737
-
-
Cordier, C.1
Morton, D.2
Murrison, S.3
Nelson, A.4
Oleary-Steele, C.5
-
10
-
-
63149092203
-
Alkaloids as potential anti-tubercular agents
-
Kishore, N.; Mishra, B. B.; Tripathi, V.; Tiwari, V. K. Alkaloids as potential anti-tubercular agents Fitoterapia 2009, 80, 149-163
-
(2009)
Fitoterapia
, vol.80
, pp. 149-163
-
-
Kishore, N.1
Mishra, B.B.2
Tripathi, V.3
Tiwari, V.K.4
-
11
-
-
0012815011
-
Total Synthesis of the Alkaloids Martinelline and Martinellic Acid via a Hetero Diels-Alder Multicomponent Coupling Reaction
-
Powell, D. A.; Batey, R. A. Total Synthesis of the Alkaloids Martinelline and Martinellic Acid via a Hetero Diels-Alder Multicomponent Coupling Reaction Org. Lett. 2002, 4, 2913-2916
-
(2002)
Org. Lett.
, vol.4
, pp. 2913-2916
-
-
Powell, D.A.1
Batey, R.A.2
-
12
-
-
0026749637
-
2-Carboxytetrahydroquinolines. Conformational and stereochemical requirements for antagonism of the glycine site on the N-methyl-D-aspartate (NMDA) receptor
-
Carling, R. W.; Lesson, P. D.; Moseley, A. M.; Baker, R.; Foster, A. C.; Grimwood, S.; Kemp, J. A.; Marshal, G. R. 2-Carboxytetrahydroquinolines. Conformational and stereochemical requirements for antagonism of the glycine site on the N-methyl-D-aspartate (NMDA) receptor J. Med. Chem. 1992, 35, 1942-1953
-
(1992)
J. Med. Chem.
, vol.35
, pp. 1942-1953
-
-
Carling, R.W.1
Lesson, P.D.2
Moseley, A.M.3
Baker, R.4
Foster, A.C.5
Grimwood, S.6
Kemp, J.A.7
Marshal, G.R.8
-
13
-
-
0027396632
-
Anticonvulsant activity of glycine-site NMDA antagonists. 2. trans 2-carboxy-4-substituted tetrahydroquinolines
-
Carling, R. W.; Lesson, P. D.; Moseley, A. M.; Smith, J. D.; Saywell, K.; Trickelbank, M. D.; Kemp, J. A.; Marshal, G. R.; Foster, A. C.; Grimwood, S. Anticonvulsant activity of glycine-site NMDA antagonists. 2. trans 2-carboxy-4-substituted tetrahydroquinolines Bioorg. Med. Chem. Lett. 1993, 3, 65-70
-
(1993)
Bioorg. Med. Chem. Lett.
, vol.3
, pp. 65-70
-
-
Carling, R.W.1
Lesson, P.D.2
Moseley, A.M.3
Smith, J.D.4
Saywell, K.5
Trickelbank, M.D.6
Kemp, J.A.7
Marshal, G.R.8
Foster, A.C.9
Grimwood, S.10
-
14
-
-
0029017727
-
Synthesis, Structure-Activity Relationships, and Pharmacological Evaluation of Pyrrolo[3,2,1-ij]quinoline Derivatives: Potent Histamine and Platelet Activating Factor Antagonism and 5-Lipoxygenase Inhibitory Properties. Potential Therapeutic Application in Asthma
-
Paris, D.; Cottin, M.; Demonchaux, P.; Augert, G.; Dupassieux, P.; Lenoir, P.; Peck, M. J.; Jasserand, D. Synthesis, Structure-Activity Relationships, and Pharmacological Evaluation of Pyrrolo[3,2,1-ij]quinoline Derivatives: Potent Histamine and Platelet Activating Factor Antagonism and 5-Lipoxygenase Inhibitory Properties. Potential Therapeutic Application in Asthma J. Med. Chem. 1995, 38, 669-685
-
(1995)
J. Med. Chem.
, vol.38
, pp. 669-685
-
-
Paris, D.1
Cottin, M.2
Demonchaux, P.3
Augert, G.4
Dupassieux, P.5
Lenoir, P.6
Peck, M.J.7
Jasserand, D.8
-
15
-
-
64949123222
-
Diversity oriented synthesis of benzimidazole and benzoxa/(thia)zole libraries through polymer-supported hypervalent iodine reagent
-
Kumar, A.; Maurya, R. A.; Ahmad, P. Diversity oriented synthesis of benzimidazole and benzoxa/(thia)zole libraries through polymer-supported hypervalent iodine reagent J. Comb. Chem. 2009, 11, 198-201
-
(2009)
J. Comb. Chem.
, vol.11
, pp. 198-201
-
-
Kumar, A.1
Maurya, R.A.2
Ahmad, P.3
-
16
-
-
74049113723
-
Diversity Oriented Synthesis of Benzoxanthene and Benzochromene Libraries via One-Pot, Three-Component Reactions and Their Anti-proliferative Activity
-
Kumar, A.; Sharma, S.; Maurya, R. A.; Sarkar, J. Diversity Oriented Synthesis of Benzoxanthene and Benzochromene Libraries via One-Pot, Three-Component Reactions and Their Anti-proliferative Activity J. Comb. Chem. 2010, 12, 20-24
-
(2010)
J. Comb. Chem.
, vol.12
, pp. 20-24
-
-
Kumar, A.1
Sharma, S.2
Maurya, R.A.3
Sarkar, J.4
-
17
-
-
77954555240
-
Diversity Oriented Synthesis of Pyrrolidines via Natural Carbohydrate Solid Acid Catalyst
-
Kumar, A.; Gupta, G.; Srivastava, S. Diversity Oriented Synthesis of Pyrrolidines via Natural Carbohydrate Solid Acid Catalyst J. Comb. Chem 2010, 12, 458-462
-
(2010)
J. Comb. Chem
, vol.12
, pp. 458-462
-
-
Kumar, A.1
Gupta, G.2
Srivastava, S.3
-
18
-
-
67650092641
-
Design and synthesis of 3,5-diarylisoxazole derivatives as novel class of anti-hyperglycemic and lipid lowering agents
-
Kumar, A.; Maurya, R. A.; Sharma, S.; Ahmad, P.; Singh, A. B.; Tamrakar, A. K.; Srivastava, A. K. Design and synthesis of 3,5-diarylisoxazole derivatives as novel class of anti-hyperglycemic and lipid lowering agents Bioorg. Med. Chem. 2009, 17, 5285-5292
-
(2009)
Bioorg. Med. Chem.
, vol.17
, pp. 5285-5292
-
-
Kumar, A.1
Maurya, R.A.2
Sharma, S.3
Ahmad, P.4
Singh, A.B.5
Tamrakar, A.K.6
Srivastava, A.K.7
-
19
-
-
73549089481
-
Synthesis and biological evaluation of N -aryl-1,4-dihydropyridines as novel antidyslipidemic and antioxidant agents
-
Kumar, A.; Maurya, R. A.; Sharma, S.; Kumar, M.; Bhatia, G. Synthesis and biological evaluation of N -aryl-1,4-dihydropyridines as novel antidyslipidemic and antioxidant agents Eur. J. Med. Chem. 2010, 45, 501-509
-
(2010)
Eur. J. Med. Chem.
, vol.45
, pp. 501-509
-
-
Kumar, A.1
Maurya, R.A.2
Sharma, S.3
Kumar, M.4
Bhatia, G.5
-
20
-
-
77953139649
-
Design and synthesis of 2,4-disubstituted polyhydroquinolines as prospective antihyperglycemic and lipid modulating agents
-
Kumar, A.; Sharma, S.; Tripathi, V. D.; Maurya, R. A.; Srivastava, S. P.; Bhatia, G.; Tamrakar, A. K.; Srivastava, A. K. Design and synthesis of 2,4-disubstituted polyhydroquinolines as prospective antihyperglycemic and lipid modulating agents Bioorg. Med. Chem. 2010, 18, 4138-4148
-
(2010)
Bioorg. Med. Chem.
, vol.18
, pp. 4138-4148
-
-
Kumar, A.1
Sharma, S.2
Tripathi, V.D.3
Maurya, R.A.4
Srivastava, S.P.5
Bhatia, G.6
Tamrakar, A.K.7
Srivastava, A.K.8
-
21
-
-
67649993673
-
2: An efficient biomimetic catalyst system providing metabolites of drug candidates
-
2: An efficient biomimetic catalyst system providing metabolites of drug candidates Bioorg. Med. Chem. Lett. 2009, 19, 4432-4436
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 4432-4436
-
-
Kumar, A.1
Maurya, R.A.2
Sharma, S.3
-
22
-
-
57949110112
-
Novel 2-aryl-naphtho[1,2- d ]oxazole derivatives as potential PTP-1B inhibitors showing antihyperglycemic activities
-
Kumar, A.; Ahmad, P.; Maurya, R. A.; Singh, A. B.; Srivastava, A. K. Novel 2-aryl-naphtho[1,2- d ]oxazole derivatives as potential PTP-1B inhibitors showing antihyperglycemic activities Eur. J. Med. Chem. 2009, 44, 109-116
-
(2009)
Eur. J. Med. Chem.
, vol.44
, pp. 109-116
-
-
Kumar, A.1
Ahmad, P.2
Maurya, R.A.3
Singh, A.B.4
Srivastava, A.K.5
-
23
-
-
0032516298
-
Convenient synthesis of pyrano[3,2- c ]quinolines and indeno[2,1- c ] quinolines by imino Diels-Alder reactions
-
Babu, G.; Perumal, P. T. Convenient synthesis of pyrano[3,2- c ]quinolines and indeno[2,1- c ] quinolines by imino Diels-Alder reactions Tetrahedron Lett. 1998, 39, 3225-3228
-
(1998)
Tetrahedron Lett.
, vol.39
, pp. 3225-3228
-
-
Babu, G.1
Perumal, P.T.2
-
24
-
-
0033588330
-
Lanthanide Chloride Catalyzed Imino Diels-Alder Reaction. One-Pot Synthesis of Pyrano[3,2- c ]- and Furo[3,2- c ]quinolines
-
Ma, Y.; Qian, C.; Xie, M.; Sun, J. Lanthanide Chloride Catalyzed Imino Diels-Alder Reaction. One-Pot Synthesis of Pyrano[3,2- c ]- and Furo[3,2- c ]quinolines J. Org. Chem. 1999, 64, 6462-6467
-
(1999)
J. Org. Chem.
, vol.64
, pp. 6462-6467
-
-
Ma, Y.1
Qian, C.2
Xie, M.3
Sun, J.4
-
25
-
-
0029813591
-
A New Methodology for Combinatorial Synthesis. Preparation of Diverse Quinoline Derivatives Using a Novel Polymer-Supported Scandium Catalyst
-
Kobayashi, S.; Nagayama, S. A New Methodology for Combinatorial Synthesis. Preparation of Diverse Quinoline Derivatives Using a Novel Polymer-Supported Scandium Catalyst J. Am. Chem. Soc. 1996, 118, 8977-8978
-
(1996)
J. Am. Chem. Soc.
, vol.118
, pp. 8977-8978
-
-
Kobayashi, S.1
Nagayama, S.2
-
26
-
-
33747322715
-
Phosphomolybdic acid-catalyzed efficient one-pot three-component aza-Diels-Alder reactions under solvent-free conditions: A facile synthesis of trans -fused pyrano- and furanotetrahydroquinolines
-
Nagaiah, K.; Sreenu, D.; Srinivasa., R.; Rao, G. V.; Yadav, J. S. Phosphomolybdic acid-catalyzed efficient one-pot three-component aza-Diels-Alder reactions under solvent-free conditions: a facile synthesis of trans -fused pyrano- and furanotetrahydroquinolines Tetrahedron Lett. 2006, 47, 4409-4413
-
(2006)
Tetrahedron Lett.
, vol.47
, pp. 4409-4413
-
-
Nagaiah, K.1
Sreenu, D.2
Srinivasa, R.3
Rao, G.V.4
Yadav, J.S.5
-
27
-
-
0030573985
-
Catalytic asymmetric aza Diels-Alder reactions using a chiral lanthanide Lewis acid. Enantioselective synthesis of tetrahydroquinoline derivatives using a catalytic amount of a chiral source
-
Ishitani, H.; Kobayashi, S. Catalytic asymmetric aza Diels-Alder reactions using a chiral lanthanide Lewis acid. Enantioselective synthesis of tetrahydroquinoline derivatives using a catalytic amount of a chiral source Tetrahedron Lett. 1996, 37, 7357-7360
-
(1996)
Tetrahedron Lett.
, vol.37
, pp. 7357-7360
-
-
Ishitani, H.1
Kobayashi, S.2
-
29
-
-
0035897147
-
Triphenyl phosphonium perchlorate-an efficient catalyst for the imino Diels-Alder reaction of imines with electron rich dienophiles. Synthesis of pyranoquinoline, furoquinoline and phenanthridine derivatives
-
Nagarajan, R.; Chitra, S.; Perumal, P. T. Triphenyl phosphonium perchlorate-an efficient catalyst for the imino Diels-Alder reaction of imines with electron rich dienophiles. Synthesis of pyranoquinoline, furoquinoline and phenanthridine derivatives Tetrahedron 2001, 57, 3419-3423
-
(2001)
Tetrahedron
, vol.57
, pp. 3419-3423
-
-
Nagarajan, R.1
Chitra, S.2
Perumal, P.T.3
-
31
-
-
0035128465
-
Litheum perchlorare/diethylether ctalyzed aza-diels-alder reaction: An expeditious synthesis of pyrani, indeno qunolines and phenathridines
-
Yadav, J. S.; Reddy, B. V. S.; Srinivas, R.; Madhuri, C.; Ramalingam, T. Litheum perchlorare/diethylether ctalyzed aza-diels-alder reaction: An expeditious synthesis of pyrani, indeno qunolines and phenathridines Synlett 2001, 240-242
-
(2001)
Synlett
, pp. 240-242
-
-
Yadav, J.S.1
Reddy, B.V.S.2
Srinivas, R.3
Madhuri, C.4
Ramalingam, T.5
-
33
-
-
0000354729
-
α -Unsaturated ethers and their analogues in reactions of diene synthesis
-
Povarov, L. S. α -Unsaturated ethers and their analogues in reactions of diene synthesis Russ. Chem. Rev. 1967, 36, 656
-
(1967)
Russ. Chem. Rev.
, vol.36
, pp. 656
-
-
Povarov, L.S.1
-
34
-
-
33846336715
-
Synthesis of polyhydroquinoline derivatives through unsymmetric Hantzsch reaction using organocatalysts
-
DOI 10.1016/j.tet.2006.12.074, PII S0040402006020412
-
Kumar, A.; Maurya, R. A. Synthesis of polyhydroquinoline derivatives through unsymmetric Hantzsch reaction using organocatalysts Tetrahedron 2007, 63, 1946-1952 (Pubitemid 46136373)
-
(2007)
Tetrahedron
, vol.63
, Issue.9
, pp. 1946-1952
-
-
Kumar, A.1
Maurya, R.A.2
-
35
-
-
39849106140
-
Organocatalysed three-component domino synthesis of 1,4-dihydropyridines under solvent free conditions
-
Kumar, A.; Maurya, R. A. Organocatalysed three-component domino synthesis of 1,4-dihydropyridines under solvent free conditions Tetrahedron 2008, 64, 3477-3482
-
(2008)
Tetrahedron
, vol.64
, pp. 3477-3482
-
-
Kumar, A.1
Maurya, R.A.2
-
36
-
-
71649083229
-
Supramolecular carbohydrate scaffold-catalyzed synthesis of tetrahydroquinolines
-
Kumar, A.; Srivastava, S.; Gupta, G. Supramolecular carbohydrate scaffold-catalyzed synthesis of tetrahydroquinolines Tetrahedron Lett. 2010, 51, 517-520
-
(2010)
Tetrahedron Lett.
, vol.51
, pp. 517-520
-
-
Kumar, A.1
Srivastava, S.2
Gupta, G.3
-
38
-
-
0034583449
-
Solid acids and their use as environmentally friendly catalysts in organic synthesis
-
Wilson, K.; Clark, J. H. Solid acids and their use as environmentally friendly catalysts in organic synthesis Pure Appl. Chem. 2000, 72, 1313-1319
-
(2000)
Pure Appl. Chem.
, vol.72
, pp. 1313-1319
-
-
Wilson, K.1
Clark, J.H.2
-
39
-
-
21844444274
-
Catalysis of liquid phase organic reactions using chemically modified mesoporous inorganic solids
-
Clark, J. H.; Macquarrie, D. J. Catalysis of liquid phase organic reactions using chemically modified mesoporous inorganic solids Chem. Commun. 1998, 853
-
(1998)
Chem. Commun.
, pp. 853
-
-
Clark, J.H.1
MacQuarrie, D.J.2
-
40
-
-
0033531748
-
A three-component coupling protocol for the synthesis of substituted hexahydropyrrolo[3,2- c ]quinolines
-
Batey, R. A.; Simoncic, P. D.; Lin, D.; Smyj, R. P.; Lough, A. J. A three-component coupling protocol for the synthesis of substituted hexahydropyrrolo[3,2- c ]quinolines Chem. Commun. 1999, 651-652
-
(1999)
Chem. Commun.
, pp. 651-652
-
-
Batey, R.A.1
Simoncic, P.D.2
Lin, D.3
Smyj, R.P.4
Lough, A.J.5
-
41
-
-
47049125207
-
Molecular iodine-catalyzed diastereoselective synthesis of cis-fused pyranobenzopyrans and furanobenzopyrans
-
Wang, J.; Xu, F.-X.; Lin, X.-F.; Wang, Y.-G. Molecular iodine-catalyzed diastereoselective synthesis of cis-fused pyranobenzopyrans and furanobenzopyrans Tetrahedron Lett. 2008, 49, 5208-5210
-
(2008)
Tetrahedron Lett.
, vol.49
, pp. 5208-5210
-
-
Wang, J.1
Xu, F.-X.2
Lin, X.-F.3
Wang, Y.-G.4
-
42
-
-
0035801853
-
4-catalyzed formation of fused pyrano- and furanobenzopyrans
-
4-catalyzed formation of fused pyrano- and furanobenzopyrans Tetrahedron Lett. 2001, 42, 6381-6384
-
(2001)
Tetrahedron Lett.
, vol.42
, pp. 6381-6384
-
-
Yadav, J.S.1
Reddy, B.V.S.2
Madhuri, C.3
Sabitha, G.4
Jagannadh, B.5
Kumar, S.K.6
Kunwar, A.C.7
-
43
-
-
0037164634
-
Diastereoselective synthesis of cis -fused pyrano and furanobenzopyrans catalyzed by indium trichloride or triphenyl phosphonium perchlorate
-
Anniyappan, M.; Muralidharan, D.; Perumal, P. T. Diastereoselective synthesis of cis -fused pyrano and furanobenzopyrans catalyzed by indium trichloride or triphenyl phosphonium perchlorate Tetrahedron 2002, 58, 10301-10307
-
(2002)
Tetrahedron
, vol.58
, pp. 10301-10307
-
-
Anniyappan, M.1
Muralidharan, D.2
Perumal, P.T.3
-
44
-
-
0030903133
-
Microplate alamar blue assay versus BACTEC 460 system for high- throughput screening of compounds against Mycobacterium tuberculosis and Mycobacterium avium
-
Collins, L. A.; Franzblan, S. G. Microplate alamar blue assay versus BACTEC 460 system for high- throughput screening of compounds against Mycobacterium tuberculosis and Mycobacterium avium Antimicrob. Agents Chemother. 1997, 41, 1004-1009
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 1004-1009
-
-
Collins, L.A.1
Franzblan, S.G.2
-
45
-
-
0026034493
-
In vitro antimycobacterial activities of newly synthesized benzoxazinorifamycins
-
Saito, H.; Tomioka, H.; Sato, K.; Emori, M.; Yamane, T.; Yamashita, K.; Hosol, K.; Hidaka, T. In vitro antimycobacterial activities of newly synthesized benzoxazinorifamycins Antimicrob. Agents Chemother. 1991, 35, 542-547
-
(1991)
Antimicrob. Agents Chemother.
, vol.35
, pp. 542-547
-
-
Saito, H.1
Tomioka, H.2
Sato, K.3
Emori, M.4
Yamane, T.5
Yamashita, K.6
Hosol, K.7
Hidaka, T.8
|