Comparison of structural changes of cell surface carbohydrates in the eustachian tube epithelium of chinchillas infected with a Streptococcus pneumoniae neuraminidase-deficient mutant or its isogenic parent strain

Microbial Pathogenesis

Volumn 31, Issue 6, 2001, Pages 309-317

  Tong, H H ^a   James, M ^a   Grants, I ^a   Liu, X ^a   Shi, G ^a   DeMaria, T F ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

Chinchilla; Eustachian tube; Lectins; Neuraminidase; Otitis media; Streptococcus pneumoniae

Indexed keywords

AGGLUTININ; CARBOHYDRATE; GALACTOSE; GENE PRODUCT; LECTIN; N ACETYLGLUCOSAMINE; PROTEIN NANA; SIALIC ACID; SIALIDASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUDITORY TUBE; BACTERIAL COLONIZATION; CELL STRUCTURE; CELL SURFACE; CHINCHILLA; CONTROLLED STUDY; ENZYME DEFICIENCY; EPITHELIUM; MIDDLE EAR; NASOPHARYNX; NONHUMAN; PEANUT; PRIORITY JOURNAL; PROTEIN BINDING; STRAIN DIFFERENCE; STREPTOCOCCUS PNEUMONIA; WHEAT GERM;

ARACHIS HYPOGAEA; CHINCHILLIDAE; SAMBUCUS; SAMBUCUS NIGRA; STREPTOCOCCUS; STREPTOCOCCUS PNEUMONIAE; TRITICUM AESTIVUM;

EID: 0035696749     PISSN: 08824010     EISSN: None     Source Type: Journal    
DOI: 10.1006/mpat.2001.0473     Document Type: Article

References (16)

1. Hydrolytic enzymes in otitis media pathognesis
2. Neuraminidase activity in middle ear effusions
3. Experimental alteration of chinchilla middle ear mucosae by bacterial neuraminidase
4. Changes in the structure of the cell surface carbohydrates of the chinchilla tubotympanum following Streptococcus pneumoniae-induced otitis media
5. Effect of intranasal inoculation of Streptococcus pneumoniae on the structure of the surface carbohydrates of the chinchilla eustachian tube and middle ear mucosa
6. Identification of an active disaccharide unit of a glycoconjugate receptor for pneumococci attaching to human pharyngeal epithelial cells
7. A neuraminidase from Streptococcus pneumoniae has the features of a surface protein
8. Cloning and characterization of nanB, a second Streptococcus pneumoniae neuraminidase gene and purification of the NanB enzyme from recombinant Escherichia coli
9. A role of pneumolysin but not neuraminidase in the hearing loss and cochlear damage induced by experimental pneumococcal meningitis in guinea pigs
10. Evaluation of the virulence of a Streptococcus pneumoniae neuraminidase-deficient mutant in nasopharyngeal colonization and development of otitis media in the chinchilla model
11. Heterogeneity of glycoconjugates in the secretory cells of the chinchilla middle ear and eustachian tubal epithelia: A lectin-gold cytochemical study
12. Sialoglycoproteins and penultimate sugar expression pattern in developing murine olfactory and respiratory mucosa
13. Purification and properties of Streptococcus pneumoniae neuraminidase
14. Additive attenuation of virulence of Streptococcus pneumoniae by mutation of the genes encoding pneumolysin and other putative neumonococcal virulence proteins
15. Expression of sialic acids in the developing murine tubotympanurr
16. Effect of lacto-N-neotetraose, asialoganglioside-GMI and neuraminidase on adherence of otitis media-associated serotypes of S. pneumoniae to chinchilla tracheal epithelium