메뉴 건너뛰기




Volumn 5, Issue 5, 2004, Pages 348-352

Urokinase-type plasminogen activator and its inhibitor type 1 predict disease outcome and therapy response in primary breast cancer

Author keywords

Adjuvant chemotherapy; Clinical response; Disease recurrence; Nodal involvement; Palliative therapy; Prognosis

Indexed keywords

ANTHRACYCLINE; ANTHRACYCLINE DERIVATIVE; ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; DOCETAXEL; EPIRUBICIN; FLUOROURACIL; GONADORELIN; METHOTREXATE; PLASMINOGEN ACTIVATOR INHIBITOR 1; TAMOXIFEN; TAXANE DERIVATIVE; TRASTUZUMAB; TUMOR MARKER; UNCLASSIFIED DRUG; UROKINASE; WX UK1;

EID: 12144261490     PISSN: 15268209     EISSN: None     Source Type: Journal    
DOI: 10.3816/CBC.2004.n.040     Document Type: Review
Times cited : (90)

References (22)
  • 1
    • 0030788411 scopus 로고    scopus 로고
    • The urokinase-type plasminogen activator system in cancer metastasis: A review
    • Andreasen PA, Kjöller L, Christensen L, et al. The urokinase-type plasminogen activator system in cancer metastasis: a review. Int J Cancer 1997; 72:1-22.
    • (1997) Int. J. Cancer , vol.72 , pp. 1-22
    • Andreasen, P.A.1    Kjöller, L.2    Christensen, L.3
  • 2
    • 0030857717 scopus 로고    scopus 로고
    • Clinical impact of the plasminogen activation system in tumor invasion and metastasis: Prognostic relevance and target for therapy
    • Schmitt M, Harbeck N, Thomssen C, et al. Clinical impact of the plasminogen activation system in tumor invasion and metastasis: prognostic relevance and target for therapy. Thromb Haemost 1997; 78:285-296.
    • (1997) Thromb. Haemost. , vol.78 , pp. 285-296
    • Schmitt, M.1    Harbeck, N.2    Thomssen, C.3
  • 3
    • 0036695216 scopus 로고    scopus 로고
    • Clinical utility of uPA/PAI-1 determination in primary breast cancer tissue for individualized therapy concepts
    • Harbeck N, Schmitt M, Kates RE, et al. Clinical utility of uPA/PAI-1 determination in primary breast cancer tissue for individualized therapy concepts. Clin Breast Cancer 2002; 3:196-200.
    • (2002) Clin. Breast Cancer , vol.3 , pp. 196-200
    • Harbeck, N.1    Schmitt, M.2    Kates, R.E.3
  • 4
    • 7844236388 scopus 로고    scopus 로고
    • External quality assessment of trans-European multicentre antigen determinations (ELISA) of urokinase-type plasminogen activator (uPA) and its type-1 inhibitor (PAI-1) in human breast cancer tissue extracts
    • Sweep CGJ, Geurts-Moespot J, Grebenschikov N, et al. External quality assessment of trans-European multicentre antigen determinations (ELISA) of urokinase-type plasminogen activator (uPA) and its type-1 inhibitor (PAI-1) in human breast cancer tissue extracts. Br J Cancer 1998; 78:1434-1441.
    • (1998) Br. J. Cancer , vol.78 , pp. 1434-1441
    • Sweep, C.G.J.1    Geurts-Moespot, J.2    Grebenschikov, N.3
  • 5
    • 0037116616 scopus 로고    scopus 로고
    • Pooled analysis of prognostic impact of uPA and PAI-1 in 8,377 breast cancer patients
    • Look MP, van Putten WLJ, Duffy MJ, et al. Pooled analysis of prognostic impact of uPA and PAI-1 in 8,377 breast cancer patients. J Natl Cancer Inst 2002; 94:116-128.
    • (2002) J. Natl. Cancer Inst. , vol.94 , pp. 116-128
    • Look, M.P.1    van Putten, W.L.J.2    Duffy, M.J.3
  • 6
    • 0141576783 scopus 로고    scopus 로고
    • Meeting highlights: Updated international expert consensus on the primary therapy of early breast cancer
    • Goldhirsch A, Wood WC, Gelber RD, et al. Meeting highlights: updated international expert consensus on the primary therapy of early breast cancer. J Clin Oncol 2003; 21:3357-3365.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 3357-3365
    • Goldhirsch, A.1    Wood, W.C.2    Gelber, R.D.3
  • 7
    • 0035918882 scopus 로고    scopus 로고
    • For the German Chemo NO Study Group: Randomized adjuvant therapy trial in high-risk lymph node-negative breast cancer patients identified by urokinase-type plasminogen activator and plasminogen activator inhibitor type I
    • Jänicke F, Prechtl A, Thomssen C, et al. For the German Chemo NO Study Group: randomized adjuvant therapy trial in high-risk lymph node-negative breast cancer patients identified by urokinase-type plasminogen activator and plasminogen activator inhibitor type I. J Natl Cancer Inst 2001; 93:913-920.
    • (2001) J. Natl. Cancer Inst. , vol.93 , pp. 913-920
    • Jänicke, F.1    Prechtl, A.2    Thomssen, C.3
  • 8
    • 33644646758 scopus 로고    scopus 로고
    • Level-I evidence for prognostic and predictive impact of uPA and PAI-1 in node-negative breast cancer provided by second scheduled analysis of multicenter Chemo-NO therapy trial
    • For the German Chemo-NO Study Group
    • Harbeck N, Meisner C, Prechtl A, et al. For the German Chemo-NO Study Group. Level-I evidence for prognostic and predictive impact of uPA and PAI-1 in node-negative breast cancer provided by second scheduled analysis of multicenter Chemo-NO therapy trial. Breast Cancer Res Treat 2001; 69:213.
    • (2001) Breast Cancer Res. Treat , vol.69 , pp. 213
    • Harbeck, N.1    Meisner, C.2    Prechtl, A.3
  • 9
    • 0037083657 scopus 로고    scopus 로고
    • Clinical relevance of invasion factors uPA and PAI-1 for individualized therapy decisions in primary breast cancer is greatest when used in combination
    • Harbeck N, Kates R, Schmitt M. Clinical relevance of invasion factors uPA and PAI-1 for individualized therapy decisions in primary breast cancer is greatest when used in combination. J Clin Oncol 2002; 20:1000-1009.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 1000-1009
    • Harbeck, N.1    Kates, R.2    Schmitt, M.3
  • 10
    • 0002961213 scopus 로고
    • Urokinase (uPA) and PAI-1 as selection criteria for adjuvant chemotherapy in axillary node-negative breast cancer patients
    • Schmitt M, Graeff H, Jänicke F, eds. Amsterdam: Elsevier Science
    • Jänicke F, Thomssen C, Pache L, et al. Urokinase (uPA) and PAI-1 as selection criteria for adjuvant chemotherapy in axillary node-negative breast cancer patients. In: Schmitt M, Graeff H, Jä nicke F, eds. Prospects in Diagnosis and Treatment of Cancer. Amsterdam: Elsevier Science; 1994:207-218.
    • (1994) Prospects in Diagnosis and Treatment of Cancer , pp. 207-218
    • Jänicke, F.1    Thomssen, C.2    Pache, L.3
  • 11
    • 0029021196 scopus 로고
    • Urokinase-type plasminogen activator and its inhibitor PAI-1: Predictors of poor response to tamoxifen therapy in recurrent breast cancer
    • Foekens JA, Look MP, Peters HA, et al. Urokinase-type plasminogen activator and its inhibitor PAI-1: predictors of poor response to tamoxifen therapy in recurrent breast cancer. J Natl Cancer Inst 1995; 87:751-756.
    • (1995) J. Natl. Cancer Inst. , vol.87 , pp. 751-756
    • Foekens, J.A.1    Look, M.P.2    Peters, H.A.3
  • 12
    • 0030743017 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 (PAI-1) is not related to response to neoadjuvant chemotherapy in breast cancer
    • Pierga JY, Laine-Bidron C, Beuzeboc P, et al. Plasminogen activator inhibitor-1 (PAI-1) is not related to response to neoadjuvant chemotherapy in breast cancer. Br J Cancer 1997; 76:537-540.
    • (1997) Br. J. Cancer , vol.76 , pp. 537-540
    • Pierga, J.Y.1    Laine-Bidron, C.2    Beuzeboc, P.3
  • 13
    • 0037102368 scopus 로고    scopus 로고
    • Enhanced benefit from adjuvant systemic chemotherapy in breast cancer patients classified high-risk according to uPA and PAI-1 (n=3,424)
    • Harbeck N, Kates RE, Look MP, et al. Enhanced benefit from adjuvant systemic chemotherapy in breast cancer patients classified high-risk according to uPA and PAI-1 (n=3,424). Cancer Res 2002; 62:4617-4622.
    • (2002) Cancer Res. , vol.62 , pp. 4617-4622
    • Harbeck, N.1    Kates, R.E.2    Look, M.P.3
  • 14
    • 0042701433 scopus 로고    scopus 로고
    • Prognostic and predictive value of the urokinase-type plasminogen activator (uPA) and its inhibitors PAI-1 and PAI-2 in operable breast cancer
    • Cufer T, Borstnar S, Vrhovec I. Prognostic and predictive value of the urokinase-type plasminogen activator (uPA) and its inhibitors PAI-1 and PAI-2 in operable breast cancer. Int J Biol Markers 2003; 18:106-115.
    • (2003) Int. J. Biol. Markers , vol.18 , pp. 106-115
    • Cufer, T.1    Borstnar, S.2    Vrhovec, I.3
  • 15
    • 10244261646 scopus 로고    scopus 로고
    • Tumor marker utility grading system: A framework to evaluate clinical utility of tumor markers
    • Hayes DF, Bast RC, Desch CE, et al. Tumor marker utility grading system: a framework to evaluate clinical utility of tumor markers. J Natl Cancer Inst 1996; 88:1456-1466.
    • (1996) J. Natl. Cancer Inst. , vol.88 , pp. 1456-1466
    • Hayes, D.F.1    Bast, R.C.2    Desch, C.E.3
  • 16
    • 18244409687 scopus 로고    scopus 로고
    • Gene expression profiling predicts clinical outcome of breast cancer
    • van't Veer LJ, Dai H, van de Vijver MJ, et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature 2002; 415:530-536.
    • (2002) Nature , vol.415 , pp. 530-536
    • van't Veer, L.J.1    Dai, H.2    van de Vijver, M.J.3
  • 17
    • 0037137519 scopus 로고    scopus 로고
    • A gene-expression signature as a predictor of survival in breast cancer
    • van de Vijver MJ, He YD, van't Veer LJ, et al. A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med 2002; 347:1999-2009.
    • (2002) N. Engl. J. Med. , vol.347 , pp. 1999-2009
    • van de Vijver, M.J.1    He, Y.D.2    van't Veer, L.J.3
  • 18
    • 1842573772 scopus 로고    scopus 로고
    • Multi-gene RT-PCR assay for predicting recurrence in node negative breast cancer patients: NSABP studies B-20 and B-14
    • (Abstract #16)
    • Paik S, Shak S, Tang G, et al. Multi-gene RT-PCR assay for predicting recurrence in node negative breast cancer patients: NSABP studies B-20 and B-14. Breast Cancer Res Treat 2003; 82(suppl 1):S10 (Abstract #16).
    • (2003) Breast Cancer Res. Treat , vol.82 , Issue.SUPPL. 1
    • Paik, S.1    Shak, S.2    Tang, G.3
  • 19
    • 12944328659 scopus 로고    scopus 로고
    • The plasminogen activation system as a novel target for therapeutic strategies
    • Schmitt M, Wilhelm OG, Reuning U, et al. The plasminogen activation system as a novel target for therapeutic strategies. Fibrinolysis 2000; 14:114-132.
    • (2000) Fibrinolysis , vol.14 , pp. 114-132
    • Schmitt, M.1    Wilhelm, O.G.2    Reuning, U.3
  • 20
    • 0035408087 scopus 로고    scopus 로고
    • Interference with the urokinase plasminogen activator system: A promising therapy concept for solid tumors
    • Muehlenweg B, Sperl S, Magdolen V, et al. Interference with the urokinase plasminogen activator system: a promising therapy concept for solid tumors. Exp Opin Biol Ther 2001; 1:683-691.
    • (2001) Exp. Opin. Biol. Ther. , vol.1 , pp. 683-691
    • Muehlenweg, B.1    Sperl, S.2    Magdolen, V.3
  • 21
    • 84898694070 scopus 로고    scopus 로고
    • Wilex Reports Positive Phase Ia Clinical Data on its Anti-Metastatic Urokinase Inhibitor WX-UK1. Located at: www.prnewswire.com/cgi-bin/stories.pl?ACCT=105&STORY= /www/story/03-18-2002/0001688348. Accessed January 10
    • Wilex Reports Positive Phase Ia Clinical Data on its Anti-Metastatic Urokinase Inhibitor WX-UK1. Located at: www.prnewswire.com/cgi-bin/stories.pl?ACCT=105&STORY= /www/story/03-18-2002/0001688348. Accessed January 10, 2004.
    • (2004)
  • 22
    • 84898696979 scopus 로고    scopus 로고
    • Fox Chase Cancer Center and Wilex Awarded First Biotechnology Clinical Partnership Grant from Department of Defense Breast Cancer Research Program. Located at: www.fccc.edu/news/2003 /Biotechnology-Clinical-Partnership-Grant-09-04-2003.html. Accessed January 12
    • Fox Chase Cancer Center and Wilex Awarded First Biotechnology Clinical Partnership Grant from Department of Defense Breast Cancer Research Program. Located at: www.fccc.edu/news/2003 /Biotechnology-Clinical-Partnership-Grant-09-04-2003.html. Accessed January 12, 2004.
    • (2004)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.