The β-blocker atenolol lowers the longevity-related degree of fatty acid unsaturation, decreases protein oxidative damage, and increases extracellular signal-regulated kinase signaling in the heart of C57BL/6 mice

Rejuvenation Research

Volumn 13, Issue 6, 2010, Pages 683-693

  Sanchez Roman, Ines ^a   Gomez, Jose ^a   Naudi, Alba ^b   Ayala, Victoria ^b   Portero Otín, Manuel ^b   Lopez Torres, Monica ^a   Pamplona, Reinald ^b   Barja, Gustavo ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b UNIVERSITY OF LLEIDA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; ATENOLOL; BETA ADRENERGIC RECEPTOR; CELL PROTEIN; CYTOCHROME C OXIDASE; MITOCHONDRIAL DNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PORIN; RAF PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE;

AGING; ANIMAL TISSUE; ARTICLE; BIRD; DRUG EFFECT; FATTY ACID DESATURATION; HEART; LONGEVITY; MALE; MAMMAL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ADRENERGIC BETA-1 RECEPTOR ANTAGONISTS; ANIMALS; ATENOLOL; BIOLOGICAL MARKERS; ELECTRON TRANSPORT; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FATTY ACIDS, UNSATURATED; GLYCOSYLATION; LONGEVITY; MAP KINASE SIGNALING SYSTEM; MEMBRANE LIPIDS; MICE; MICE, INBRED C57BL; MITOCHONDRIA, HEART; MYOCARDIUM; OXIDATION-REDUCTION; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES;

ANIMALIA; AVES; MAMMALIA; MUS;

EID: 78651331718     PISSN: 15491684     EISSN: None     Source Type: Journal    
DOI: 10.1089/rej.2010.1062     Document Type: Article

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