3,3′-Diindolylmethane decreases VCAM-1 expression and alleviates experimental colitis via a BRCA1-dependent antioxidant pathway

Free Radical Biology and Medicine

Volumn 50, Issue 2, 2011, Pages 228-236

  Huang, Zhen ^a   Zuo, Longsheng ^a   Zhang, Zhengping ^a   Liu, Jialin ^a   Chen, Jiangning ^a   Dong, Lei ^a   Zhang, Junfeng ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

3,3 Diindolylmethane; Free radicals; Inflammatory bowel disease; Reactive oxygen species; Vascular cell adhesion molecule 1

Indexed keywords

3,3' DIINDOLYLMETHANE; BRCA1 ASSOCIATED RING DOMAIN PROTEIN 1; REACTIVE OXYGEN METABOLITE; TRINITROBENZENESULFONIC ACID; VASCULAR CELL ADHESION MOLECULE 1; 3,3'-DIINDOLYLMETHANE; ANTIOXIDANT; BRCA1 PROTEIN; INDOLE DERIVATIVE; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL INTERACTION; COLITIS; CONTROLLED STUDY; DRUG MECHANISM; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; LEUKOCYTE ADHERENCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; BAGG ALBINO MOUSE; CELL ADHESION; CHEMICALLY INDUCED DISORDER; CYTOLOGY; DRUG EFFECT; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; LEUKOCYTE; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UMBILICAL VEIN; VASCULAR ENDOTHELIUM; WESTERN BLOTTING;

ANIMALIA;

ANIMALS; ANTIOXIDANTS; BLOTTING, WESTERN; BRCA1 PROTEIN; CELL ADHESION; COLITIS; ENDOTHELIUM, VASCULAR; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; INDOLES; LEUKOCYTES; MICE; MICE, INBRED BALB C; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRINITROBENZENESULFONIC ACID; UMBILICAL VEINS; VASCULAR CELL ADHESION MOLECULE-1;

EID: 78651238595     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2010.10.703     Document Type: Article

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