메뉴 건너뛰기




Volumn 132, Issue 2, 2006, Pages 208-213

3,3′-Diindolylmethane and Paclitaxel Act Synergistically to Promote Apoptosis in HER2/Neu Human Breast Cancer Cells

Author keywords

3,3 diindolylmethane; apoptosis; breast cancer; HER2 neu; paclitaxel

Indexed keywords

3,3' DIINDOLYLMETHANE; 3,3'-DIINDOLYLMETHANE; ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; INDOLE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PACLITAXEL;

EID: 33646088121     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2006.02.008     Document Type: Article
Times cited : (48)

References (33)
  • 1
    • 0024337144 scopus 로고
    • Studies of the HER2/neu proto-oncogene in human breast and ovarian cancer
    • Slamon D.J., Godopphin W., Jones L.A., et al. Studies of the HER2/neu proto-oncogene in human breast and ovarian cancer. Science 244 (1989) 707
    • (1989) Science , vol.244 , pp. 707
    • Slamon, D.J.1    Godopphin, W.2    Jones, L.A.3
  • 2
    • 0026625217 scopus 로고
    • Prognostic importance of c-erbB2 expression in breast cancer
    • International Breast Cancer Study Group
    • Gusterson B.A., Gelber R.D., Goldhirsch A., et al., International Breast Cancer Study Group. Prognostic importance of c-erbB2 expression in breast cancer. J Clin Oncol 10 (1992) 1049
    • (1992) J Clin Oncol , vol.10 , pp. 1049
    • Gusterson, B.A.1    Gelber, R.D.2    Goldhirsch, A.3
  • 3
    • 0031775808 scopus 로고    scopus 로고
    • Predictive value of topoisomerase II alpha and other prognostic factors for epirubicin chemotherapy in advanced breast cancer
    • Jarvinen T.A., Holli K., Kuukasjarvi T., et al. Predictive value of topoisomerase II alpha and other prognostic factors for epirubicin chemotherapy in advanced breast cancer. Br J Cancer 77 (1998) 2267
    • (1998) Br J Cancer , vol.77 , pp. 2267
    • Jarvinen, T.A.1    Holli, K.2    Kuukasjarvi, T.3
  • 4
    • 0029830451 scopus 로고    scopus 로고
    • Overexpression of cErbB-2/neu in breast cancer cells confers increased resistance to Taxol via mdr-1 independent mechanisms
    • Yu D., Liu B., Tan M.J., et al. Overexpression of cErbB-2/neu in breast cancer cells confers increased resistance to Taxol via mdr-1 independent mechanisms. Oncogene 13 (1996) 1359
    • (1996) Oncogene , vol.13 , pp. 1359
    • Yu, D.1    Liu, B.2    Tan, M.J.3
  • 5
    • 0032559889 scopus 로고    scopus 로고
    • Overexpression of p185cErbB2 and p170mdr-1 renders breast cancer cells highly resistant to paclitaxel
    • Yu D., Liu B., Jing T., et al. Overexpression of p185cErbB2 and p170mdr-1 renders breast cancer cells highly resistant to paclitaxel. Oncogene 16 (1998) 2087
    • (1998) Oncogene , vol.16 , pp. 2087
    • Yu, D.1    Liu, B.2    Jing, T.3
  • 6
    • 0345305212 scopus 로고    scopus 로고
    • Combined effects of resveratrol and paclitaxel on lung cancer cells
    • Kubota T., Uemura Y., Kobayashi M., and Taguchi H. Combined effects of resveratrol and paclitaxel on lung cancer cells. Anticancer Res 23 (2003) 4039
    • (2003) Anticancer Res , vol.23 , pp. 4039
    • Kubota, T.1    Uemura, Y.2    Kobayashi, M.3    Taguchi, H.4
  • 7
    • 0035942499 scopus 로고    scopus 로고
    • Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells
    • Chinni S.R., Li Y., Upadhyay S., et al. Indole-3-carbinol (I3C) induced cell growth inhibition, G1 cell cycle arrest and apoptosis in prostate cancer cells. Oncogene 20 (2001) 2927
    • (2001) Oncogene , vol.20 , pp. 2927
    • Chinni, S.R.1    Li, Y.2    Upadhyay, S.3
  • 8
    • 0033842270 scopus 로고    scopus 로고
    • Placebo-controlled trial of indole-3-carbinol in the treatment of CIN
    • Bell M.C., Crowley-Nowick P., Bradlow H.L., et al. Placebo-controlled trial of indole-3-carbinol in the treatment of CIN. Gynecol Oncol 78 (2000) 123
    • (2000) Gynecol Oncol , vol.78 , pp. 123
    • Bell, M.C.1    Crowley-Nowick, P.2    Bradlow, H.L.3
  • 9
    • 0025776365 scopus 로고
    • Effects of dietary indole-3-carbinol on estradiol metabolism and spontaneous mammary tumors in mice
    • Bradlow H.L., Michnovicz J., Telang N.T., et al. Effects of dietary indole-3-carbinol on estradiol metabolism and spontaneous mammary tumors in mice. Carcinogenesis 12 (1991) 1571
    • (1991) Carcinogenesis , vol.12 , pp. 1571
    • Bradlow, H.L.1    Michnovicz, J.2    Telang, N.T.3
  • 10
    • 4544358789 scopus 로고    scopus 로고
    • Therapeutic activity of 3,3′-diindolylmethane on prostate cancer in an in vivo model
    • Nachshon-Kedmi M., Fares F.A., and Yannai S. Therapeutic activity of 3,3′-diindolylmethane on prostate cancer in an in vivo model. The Prostate 61 (2004) 153
    • (2004) The Prostate , vol.61 , pp. 153
    • Nachshon-Kedmi, M.1    Fares, F.A.2    Yannai, S.3
  • 11
    • 0028088840 scopus 로고
    • Selective response of human breast cancer cells to indole-3-carbinol, a chemopreventive agent
    • Tiwari R.K., Guo L., Bradlow H.L., et al. Selective response of human breast cancer cells to indole-3-carbinol, a chemopreventive agent. J Natl Cancer Inst 86 (1994) 126
    • (1994) J Natl Cancer Inst , vol.86 , pp. 126
    • Tiwari, R.K.1    Guo, L.2    Bradlow, H.L.3
  • 12
    • 0032512820 scopus 로고    scopus 로고
    • Indole-3-carbinol inhibits the expression of cyclin-dependent kinase-6 and induces a G1 cell cycle arrest of human breast cancer cells independent of estrogen receptor signaling
    • Cover C.M., Hsieh S.J., Tran S.H., et al. Indole-3-carbinol inhibits the expression of cyclin-dependent kinase-6 and induces a G1 cell cycle arrest of human breast cancer cells independent of estrogen receptor signaling. J Biol Chem 273 (1998) 3838
    • (1998) J Biol Chem , vol.273 , pp. 3838
    • Cover, C.M.1    Hsieh, S.J.2    Tran, S.H.3
  • 13
    • 0030881402 scopus 로고    scopus 로고
    • Inhibition of proliferation and modulation of estradiol metabolism. Novel mechanisms for breast cancer prevention by the phytochemical indole-3-carbinol
    • Telang N.T., Katdare M., Bradloe H.L., et al. Inhibition of proliferation and modulation of estradiol metabolism. Novel mechanisms for breast cancer prevention by the phytochemical indole-3-carbinol. Proc Soc Exp Biol Med 216 (1997) 246
    • (1997) Proc Soc Exp Biol Med , vol.216 , pp. 246
    • Telang, N.T.1    Katdare, M.2    Bradloe, H.L.3
  • 14
    • 0033559197 scopus 로고    scopus 로고
    • Indole-3-carbinol and tamoxifen cooperate to arrest the cell cycle of MCF-7 human breast cancer cells
    • Cover C.M., Hsieh S.J., Cram E.J., et al. Indole-3-carbinol and tamoxifen cooperate to arrest the cell cycle of MCF-7 human breast cancer cells. Cancer Res 59 (1999) 1244
    • (1999) Cancer Res , vol.59 , pp. 1244
    • Cover, C.M.1    Hsieh, S.J.2    Cram, E.J.3
  • 15
    • 0035984590 scopus 로고    scopus 로고
    • 3,3′- Diindolylmethane (DIM) induces a G1 cell cycle arrest in human breast cancer cells that is accompanied by Sp1-mediated activation of p21 WAF1/CIP1 expression
    • Hong C., Kim H.A., Firestone G.L., and Bjeldanes L.F. 3,3′- Diindolylmethane (DIM) induces a G1 cell cycle arrest in human breast cancer cells that is accompanied by Sp1-mediated activation of p21 WAF1/CIP1 expression. Carcinogenesis 23 (2002) 1297
    • (2002) Carcinogenesis , vol.23 , pp. 1297
    • Hong, C.1    Kim, H.A.2    Firestone, G.L.3    Bjeldanes, L.F.4
  • 16
    • 0030297325 scopus 로고    scopus 로고
    • 3,3′-Diindolylmethane induces apoptosis in human cancer cells
    • Ge X., Yannai S., Rennert G., et al. 3,3′-Diindolylmethane induces apoptosis in human cancer cells. Biochem Biophys Res Commun 228 (1996) 153
    • (1996) Biochem Biophys Res Commun , vol.228 , pp. 153
    • Ge, X.1    Yannai, S.2    Rennert, G.3
  • 17
    • 0034706910 scopus 로고    scopus 로고
    • Translocation of Bax to mitochondria induces apoptotic cell death in Indole-3-carbinol treated breast cancer cells
    • Rahman K.M., Aranha O., Glazyrin A., Chinni S., and Sarkar F. Translocation of Bax to mitochondria induces apoptotic cell death in Indole-3-carbinol treated breast cancer cells. Oncogene 19 (2000) 5764
    • (2000) Oncogene , vol.19 , pp. 5764
    • Rahman, K.M.1    Aranha, O.2    Glazyrin, A.3    Chinni, S.4    Sarkar, F.5
  • 18
    • 0041952943 scopus 로고    scopus 로고
    • Indole-3-carbinol inhibits protein kinase B/Akt and induces apoptosis in the human breast tumor cell line MDA MB468 but not in the nontumorigenic HBL100 line
    • Howells L.M., Gallacher-Horley B., Houghton C.E., Manson M.M., and Hudson E.A. Indole-3-carbinol inhibits protein kinase B/Akt and induces apoptosis in the human breast tumor cell line MDA MB468 but not in the nontumorigenic HBL100 line. Mol Cancer Ther 1 (2002) 1161
    • (2002) Mol Cancer Ther , vol.1 , pp. 1161
    • Howells, L.M.1    Gallacher-Horley, B.2    Houghton, C.E.3    Manson, M.M.4    Hudson, E.A.5
  • 19
    • 3042642131 scopus 로고    scopus 로고
    • Inactivation of akt and NF-kappaB play important roles during indole-3-carbinol-induced apoptosis in breast cancer cells
    • Rahman Li Y., and Sarkar F.H. Inactivation of akt and NF-kappaB play important roles during indole-3-carbinol-induced apoptosis in breast cancer cells. Nutr Cancer 48 (2004) 84
    • (2004) Nutr Cancer , vol.48 , pp. 84
    • Rahman Li, Y.1    Sarkar, F.H.2
  • 20
    • 11244282153 scopus 로고    scopus 로고
    • Inhibition of nuclear translocation of nuclear factor-kappaB contributes to 3,3′-diindolylmethane-induced apoptosis in breast cancer cells
    • Rahman Li Y., and Sarkar F.H. Inhibition of nuclear translocation of nuclear factor-kappaB contributes to 3,3′-diindolylmethane-induced apoptosis in breast cancer cells. Cancer Res 65 (2005) 364
    • (2005) Cancer Res , vol.65 , pp. 364
    • Rahman Li, Y.1    Sarkar, F.H.2
  • 21
    • 0026625217 scopus 로고
    • Prognostic importance of c-erbB2 expression in breast cancer
    • International Breast Cancer Study Group
    • Gusterson B.A., Gelber R.D., Goldhirsch A., et al., International Breast Cancer Study Group. Prognostic importance of c-erbB2 expression in breast cancer. J Clin Oncol 10 (1992) 1049
    • (1992) J Clin Oncol , vol.10 , pp. 1049
    • Gusterson, B.A.1    Gelber, R.D.2    Goldhirsch, A.3
  • 22
    • 0031775808 scopus 로고    scopus 로고
    • Predictive value of topoisomerase II alpha and other prognostic factors for epirubicin chemotherapy in advanced breast cancer
    • Jarvinen T.A., Holli K., Kuukasjarvi T., et al. Predictive value of topoisomerase II alpha and other prognostic factors for epirubicin chemotherapy in advanced breast cancer. Br J Cancer 77 (1998) 2267
    • (1998) Br J Cancer , vol.77 , pp. 2267
    • Jarvinen, T.A.1    Holli, K.2    Kuukasjarvi, T.3
  • 23
    • 0029830451 scopus 로고    scopus 로고
    • Overexpression of cErbB-2/neu in breast cancer cells confers increased resistance to Taxol via mdr-1 independent mechanisms
    • Yu D., Liu B., Tan M.J., et al. Overexpression of cErbB-2/neu in breast cancer cells confers increased resistance to Taxol via mdr-1 independent mechanisms. Oncogene 13 (1996) 1359
    • (1996) Oncogene , vol.13 , pp. 1359
    • Yu, D.1    Liu, B.2    Tan, M.J.3
  • 24
    • 0032559889 scopus 로고    scopus 로고
    • Overexpression of p185cErbB2 and p170mdr-1 renders breast cancer cells highly resistant to paclitaxel
    • Yu D., Liu B., Jing T., et al. Overexpression of p185cErbB2 and p170mdr-1 renders breast cancer cells highly resistant to paclitaxel. Oncogene 16 (1998) 2087
    • (1998) Oncogene , vol.16 , pp. 2087
    • Yu, D.1    Liu, B.2    Jing, T.3
  • 25
    • 0037087501 scopus 로고    scopus 로고
    • Bcl-2 family-mediated apoptotic effects of 3,3′-diindolylmethane (DIM) in human breast cancer cells
    • Hong C., Firestone G.L., and Bjeldanes L.F. Bcl-2 family-mediated apoptotic effects of 3,3′-diindolylmethane (DIM) in human breast cancer cells. Biochem Pharmacol 63 (2002) 1085
    • (2002) Biochem Pharmacol , vol.63 , pp. 1085
    • Hong, C.1    Firestone, G.L.2    Bjeldanes, L.F.3
  • 26
    • 0036860304 scopus 로고    scopus 로고
    • In vitro comparative evaluation of trastuzumab (Herceptin) combined with paclitaxel
    • Merlin J.L., Barberi-Heyob M., and Bachmann N. In vitro comparative evaluation of trastuzumab (Herceptin) combined with paclitaxel. Ann Oncol 13 (2002) 1743
    • (2002) Ann Oncol , vol.13 , pp. 1743
    • Merlin, J.L.1    Barberi-Heyob, M.2    Bachmann, N.3
  • 27
    • 0037108866 scopus 로고    scopus 로고
    • Enhanced sensitization to taxol-induced apoptosis by herceptin pretreatment in ErbB2-overexpressing breast cancer cells
    • Lee S., Yang W., Lan K.H., et al. Enhanced sensitization to taxol-induced apoptosis by herceptin pretreatment in ErbB2-overexpressing breast cancer cells. Cancer Res 62 (2002) 5703
    • (2002) Cancer Res , vol.62 , pp. 5703
    • Lee, S.1    Yang, W.2    Lan, K.H.3
  • 29
    • 5144228218 scopus 로고    scopus 로고
    • Cell signaling pathways altered by natural chemopreventive agents
    • Sarkar F.H., and Li Y. Cell signaling pathways altered by natural chemopreventive agents. Mutat Res 555 (2004) 53
    • (2004) Mutat Res , vol.555 , pp. 53
    • Sarkar, F.H.1    Li, Y.2
  • 30
    • 33646106026 scopus 로고    scopus 로고
    • Inhibition of growth factor-induced ras signaling in vascular endothelial cells and angiogenesis by 3,3′-diindolylmethane
    • Chang X., Firestone G.L., and Bjeldanes L.F. Inhibition of growth factor-induced ras signaling in vascular endothelial cells and angiogenesis by 3,3′-diindolylmethane. Carcinogenesis (2005) 2301
    • (2005) Carcinogenesis , pp. 2301
    • Chang, X.1    Firestone, G.L.2    Bjeldanes, L.F.3
  • 31
    • 2442689845 scopus 로고    scopus 로고
    • New formulation strategies for bioavailability enhancement of two poorly absorbed phytonutrient supplements. Diindolylmethane and yohimbine bark extract
    • Jacobs I.C., and Zeligs M.A. New formulation strategies for bioavailability enhancement of two poorly absorbed phytonutrient supplements. Diindolylmethane and yohimbine bark extract. Proc Int Sym Control Rel Bioact Mater 27 (2000) 1324
    • (2000) Proc Int Sym Control Rel Bioact Mater , vol.27 , pp. 1324
    • Jacobs, I.C.1    Zeligs, M.A.2
  • 32
    • 0141787069 scopus 로고    scopus 로고
    • Combined trastuzumab and paclitaxel treatment better inhibits ErbB-2-mediated angiogenesis in breast carcinoma through a more effective inhibition of Akt than either treatment alone
    • Klos K.S., Zhou X., Lee S., Zhang L., Yang W., Nagata Y., and Yu D. Combined trastuzumab and paclitaxel treatment better inhibits ErbB-2-mediated angiogenesis in breast carcinoma through a more effective inhibition of Akt than either treatment alone. Cancer 98 (2003) 1377
    • (2003) Cancer , vol.98 , pp. 1377
    • Klos, K.S.1    Zhou, X.2    Lee, S.3    Zhang, L.4    Yang, W.5    Nagata, Y.6    Yu, D.7
  • 33
    • 0031813790 scopus 로고    scopus 로고
    • Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase
    • Srivastava R.K., Srivastava A.R., Korsmeyer S.J., Nesterova M., Cho-Chung Y.S., and Longo D.L. Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase. Mol Cell Biol 18 (1998) 3509
    • (1998) Mol Cell Biol , vol.18 , pp. 3509
    • Srivastava, R.K.1    Srivastava, A.R.2    Korsmeyer, S.J.3    Nesterova, M.4    Cho-Chung, Y.S.5    Longo, D.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.