Gd-complexes of 1,4,7,10-tetraazacyclododecane- N, N′, N ″, N ‴-1,4,7,10-tetraacetic acid (DOTA) conjugates of tranexamates as a new class of blood-pool magnetic resonance imaging contrast agents

Journal of Medicinal Chemistry

Volumn 54, Issue 1, 2011, Pages 143-152

  Gu, Sungwook ^a   Kim, Hee Kyung ^a   Lee, Gang Ho ^a   Kang, Bong Seok ^a   Chang, Yongmin ^a   Kim, Tae Jeong ^a  

^a Kyungpook National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; CHELATE; GADOLINIUM; GADOTERIC ACID; GADOVERSETAMIDE; NUCLEAR MAGNETIC RESONANCE IMAGING AGENT; TRANEXAMIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTRAST ENHANCEMENT; CYTOTOXICITY TEST; DRUG STRUCTURE; DRUG UPTAKE; EMBRYO; HUMAN; HUMAN CELL; LIPOPHILICITY; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; THERMODYNAMICS;

ANIMALS; BLOOD; CELL LINE; CONTRAST MEDIA; COORDINATION COMPLEXES; ESTERS; GADOLINIUM; HETEROCYCLIC COMPOUNDS, 1-RING; HUMANS; LIVER; MAGNETIC RESONANCE IMAGING; MALE; MICE; MICE, INBRED ICR; ORGAN SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP; TRANEXAMIC ACID;

EID: 78651087349     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm100966t     Document Type: Article

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