Apparent desensitization of the effects of sigma receptor ligand haloperidol in isolated rat and guinea pig hearts after chronic treatment

Canadian Journal of Physiology and Pharmacology

Volumn 87, Issue 12, 2009, Pages 1019-1027

  Fialova, Katerina ^a   Krizanova, Olga ^b   Jarkovsky, Jiri ^a   Novakova, Marie ^a  

^a MASARYK UNIVERSITY   (Czech Republic)

^b INSTITUTE OF MOLECULAR PHYSIOLOGY AND GENETICS   (Slovakia)

Author keywords

Arrhythmia; Desensitization; Guinea pig; Haloperidol; Isolated heart; QT interval; Rat; Sigma receptor

Indexed keywords

HALOPERIDOL; SIGMA RECEPTOR LIGAND;

ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; DESENSITIZATION; DRUG EFFECT; HEART ARRHYTHMIA; HEART RATE; ISOLATED HEART; NONHUMAN; PRIORITY JOURNAL; QT INTERVAL; QT PROLONGATION; RAT;

ANIMALS; ARRHYTHMIAS, CARDIAC; ELECTROCARDIOGRAM PATTERN; GUINEA PIGS; HALOPERIDOL; HEART; HEART RATE; RATS; RATS, WISTAR; RECEPTORS, SIGMA; TORSADES DE POINTES;

EID: 76549092213     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/Y09-066     Document Type: Conference Paper

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