메뉴 건너뛰기




Volumn 90, Issue 2, 2011, Pages 173-178

MicroRNAs in chronic lymphocytic leukemia

Author keywords

Chronic lymphocytic leukemia; MiRNA; Pathogenesis

Indexed keywords

FLUDARABINE; MESSENGER RNA; MICRORNA; MICRORNA 15A; MICRORNA 16; MICRORNA 181; MICRORNA 29; OLIGONUCLEOTIDE; PROTEIN KINASE ZAP 70; RNA PRECURSOR; TUMOR MARKER; UNCLASSIFIED DRUG; UNTRANSLATED RNA;

EID: 78650995476     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2010.12.002     Document Type: Review
Times cited : (11)

References (83)
  • 1
    • 77953175143 scopus 로고    scopus 로고
    • National Cancer Institute, Bethesda, MD, based on November 2009 SEER data submission, posted to the SEER web site, S.F. Altekruse, C.L. Kosary, M. Krapcho, N. Neyman, R. Aminou, W. Waldron (Eds.)
    • SEER Cancer Statistics Review, 1975-2007 2010, National Cancer Institute, Bethesda, MD, based on November 2009 SEER data submission, posted to the SEER web site. http://seer.cancer.gov/csr/1975_2007/, S.F. Altekruse, C.L. Kosary, M. Krapcho, N. Neyman, R. Aminou, W. Waldron (Eds.).
    • (2010) SEER Cancer Statistics Review, 1975-2007
  • 2
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros V. The functions of animal microRNAs. Nature 2004, 431:350-355.
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 3
    • 77953648407 scopus 로고    scopus 로고
    • MicroRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia
    • Asslaber D., Pinon J.D., Seyfried I., Desch P., Stocher M., Tinhofer I., et al. microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia. Blood 2010, 115:4191-4197.
    • (2010) Blood , vol.115 , pp. 4191-4197
    • Asslaber, D.1    Pinon, J.D.2    Seyfried, I.3    Desch, P.4    Stocher, M.5    Tinhofer, I.6
  • 4
    • 67650422613 scopus 로고    scopus 로고
    • MiR-15a and miR-16 are implicated in cell cycle regulation in a Rb-dependent manner and are frequently deleted or down-regulated in non-small cell lung cancer
    • Bandi N., Zbinden S., Gugger M., Arnold M., Kocher V., Hasan L., et al. miR-15a and miR-16 are implicated in cell cycle regulation in a Rb-dependent manner and are frequently deleted or down-regulated in non-small cell lung cancer. Cancer Res. 2009, 69:5553-5559.
    • (2009) Cancer Res. , vol.69 , pp. 5553-5559
    • Bandi, N.1    Zbinden, S.2    Gugger, M.3    Arnold, M.4    Kocher, V.5    Hasan, L.6
  • 5
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: target recognition and regulatory functions
    • Bartel D.P. MicroRNAs: target recognition and regulatory functions. Cell 2009, 136:215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 6
    • 1942435249 scopus 로고    scopus 로고
    • Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs
    • Bartel D.P., Chen C.Z. Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs. Nat. Rev. Genet. 2004, 5:396-400.
    • (2004) Nat. Rev. Genet. , vol.5 , pp. 396-400
    • Bartel, D.P.1    Chen, C.Z.2
  • 7
    • 64149132942 scopus 로고    scopus 로고
    • MicroRNAs: novel biomarkers for human cancer
    • Bartels C.L., Tsongalis G.J. MicroRNAs: novel biomarkers for human cancer. Clin. Chem. 2009, 55:623-631.
    • (2009) Clin. Chem. , vol.55 , pp. 623-631
    • Bartels, C.L.1    Tsongalis, G.J.2
  • 8
    • 22844440427 scopus 로고    scopus 로고
    • Identification of hundreds of conserved and nonconserved human microRNAs
    • Bentwich I., Avniel A., Karov Y., Aharonov R., Gilad S., Barad O., et al. Identification of hundreds of conserved and nonconserved human microRNAs. Nat. Genet. 2005, 37:766-770.
    • (2005) Nat. Genet. , vol.37 , pp. 766-770
    • Bentwich, I.1    Avniel, A.2    Karov, Y.3    Aharonov, R.4    Gilad, S.5    Barad, O.6
  • 11
    • 33748484481 scopus 로고    scopus 로고
    • ZAP-70 by flow cytometry: a comparison of different antibodies, anticoagulants, and methods of analysis
    • Best O.G., Ibbotson R.E., Parker A.E., Davis Z.A., Orchard J.A., Oscier D.G. ZAP-70 by flow cytometry: a comparison of different antibodies, anticoagulants, and methods of analysis. Cytom. B Clin. Cytom. 2006, 70:235-241.
    • (2006) Cytom. B Clin. Cytom. , vol.70 , pp. 235-241
    • Best, O.G.1    Ibbotson, R.E.2    Parker, A.E.3    Davis, Z.A.4    Orchard, J.A.5    Oscier, D.G.6
  • 13
    • 0019427092 scopus 로고
    • A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysis
    • Binet J.L., Auquier A., Dighiero G., Chastang C., Piguet H., Goasguen J., et al. A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysis. Cancer 1981, 48:198-206.
    • (1981) Cancer , vol.48 , pp. 198-206
    • Binet, J.L.1    Auquier, A.2    Dighiero, G.3    Chastang, C.4    Piguet, H.5    Goasguen, J.6
  • 16
    • 0035884425 scopus 로고    scopus 로고
    • Characterization of the 13q14 tumor suppressor locus in CLL: identification of ALT1, an alternative splice variant of the LEU2 gene
    • Bullrich F., Fujii H., Calin G., Mabuchi H., Negrini M., Pekarsky Y., et al. Characterization of the 13q14 tumor suppressor locus in CLL: identification of ALT1, an alternative splice variant of the LEU2 gene. Cancer Res. 2001, 61:6640-6648.
    • (2001) Cancer Res. , vol.61 , pp. 6640-6648
    • Bullrich, F.1    Fujii, H.2    Calin, G.3    Mabuchi, H.4    Negrini, M.5    Pekarsky, Y.6
  • 17
    • 33751099034 scopus 로고    scopus 로고
    • RNAi therapeutics: a potential new class of pharmaceutical drugs
    • Bumcrot D., Manoharan M., Koteliansky V., Sah D.W. RNAi therapeutics: a potential new class of pharmaceutical drugs. Nat. Chem. Biol. 2006, 2:711-719.
    • (2006) Nat. Chem. Biol. , vol.2 , pp. 711-719
    • Bumcrot, D.1    Manoharan, M.2    Koteliansky, V.3    Sah, D.W.4
  • 18
    • 18744396337 scopus 로고    scopus 로고
    • Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
    • Calin G.A., Dumitru C.D., Shimizu M., Bichi R., Zupo S., Noch E., et al. Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc. Natl Acad. Sci. USA 2002, 99:15524-15529.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 15524-15529
    • Calin, G.A.1    Dumitru, C.D.2    Shimizu, M.3    Bichi, R.4    Zupo, S.5    Noch, E.6
  • 20
    • 27244434788 scopus 로고    scopus 로고
    • A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia
    • Calin G.A., Ferracin M., Cimmino A., Di Leva G., Shimizu M., Wojcik S.E., et al. A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N. Engl. J. Med. 2005, 353:1793-1801.
    • (2005) N. Engl. J. Med. , vol.353 , pp. 1793-1801
    • Calin, G.A.1    Ferracin, M.2    Cimmino, A.3    Di Leva, G.4    Shimizu, M.5    Wojcik, S.E.6
  • 21
    • 34249817549 scopus 로고    scopus 로고
    • Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
    • Chang T.C., Wentzel E.A., Kent O.A., Ramachandran K., Mullendore M., Lee K.H., et al. Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol. Cell 2007, 26:745-752.
    • (2007) Mol. Cell , vol.26 , pp. 745-752
    • Chang, T.C.1    Wentzel, E.A.2    Kent, O.A.3    Ramachandran, K.4    Mullendore, M.5    Lee, K.H.6
  • 24
    • 34548803950 scopus 로고    scopus 로고
    • MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth
    • Corney D.C., Flesken-Nikitin A., Godwin A.K., Wang W., Nikitin A.Y. MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth. Cancer Res. 2007, 67:8433-8438.
    • (2007) Cancer Res. , vol.67 , pp. 8433-8438
    • Corney, D.C.1    Flesken-Nikitin, A.2    Godwin, A.K.3    Wang, W.4    Nikitin, A.Y.5
  • 25
    • 0037406968 scopus 로고    scopus 로고
    • ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia
    • Crespo M., Bosch F., Villamor N., Bellosillo B., Colomer D., Rozman M., et al. ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia. N. Engl. J. Med. 2003, 348:1764-1775.
    • (2003) N. Engl. J. Med. , vol.348 , pp. 1764-1775
    • Crespo, M.1    Bosch, F.2    Villamor, N.3    Bellosillo, B.4    Colomer, D.5    Rozman, M.6
  • 26
    • 0033567968 scopus 로고    scopus 로고
    • Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia
    • Damle R.N., Wasil T., Fais F., Ghiotto F., Valetto A., Allen S.L., et al. Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. Blood 1999, 94:1840-1847.
    • (1999) Blood , vol.94 , pp. 1840-1847
    • Damle, R.N.1    Wasil, T.2    Fais, F.3    Ghiotto, F.4    Valetto, A.5    Allen, S.L.6
  • 27
    • 40749132494 scopus 로고    scopus 로고
    • Chronic lymphocytic leukaemia
    • Dighiero G., Hamblin T.J. Chronic lymphocytic leukaemia. Lancet 2008, 371:1017-1029.
    • (2008) Lancet , vol.371 , pp. 1017-1029
    • Dighiero, G.1    Hamblin, T.J.2
  • 28
  • 29
    • 0032532668 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors
    • Fais F., Ghiotto F., Hashimoto S., Sellars B., Valetto A., Allen S.L., et al. Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors. J. Clin. Invest. 1998, 102:1515.
    • (1998) J. Clin. Invest. , vol.102 , pp. 1515
    • Fais, F.1    Ghiotto, F.2    Hashimoto, S.3    Sellars, B.4    Valetto, A.5    Allen, S.L.6
  • 30
    • 34249661649 scopus 로고    scopus 로고
    • Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia
    • Fulci V., Chiaretti S., Goldoni M., Azzalin G., Carucci N., Tavolaro S., et al. Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia. Blood 2007, 109:4944-4951.
    • (2007) Blood , vol.109 , pp. 4944-4951
    • Fulci, V.1    Chiaretti, S.2    Goldoni, M.3    Azzalin, G.4    Carucci, N.5    Tavolaro, S.6
  • 33
    • 33947544426 scopus 로고    scopus 로고
    • Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: results from the US Intergroup Phase III Trial E2997
    • Grever M.R., Lucas D.M., Dewald G.W., Neuberg D.S., Reed J.C., Kitada S., et al. Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: results from the US Intergroup Phase III Trial E2997. J. Clin. Oncol. 2007, 25:799-804.
    • (2007) J. Clin. Oncol. , vol.25 , pp. 799-804
    • Grever, M.R.1    Lucas, D.M.2    Dewald, G.W.3    Neuberg, D.S.4    Reed, J.C.5    Kitada, S.6
  • 34
    • 45149100665 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines
    • Hallek M., Cheson B.D., Catovsky D., Caligaris-Cappio F., Dighiero G., Dohner H., et al. Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines. Blood 2008, 111:5446-5456.
    • (2008) Blood , vol.111 , pp. 5446-5456
    • Hallek, M.1    Cheson, B.D.2    Catovsky, D.3    Caligaris-Cappio, F.4    Dighiero, G.5    Dohner, H.6
  • 35
    • 0033567907 scopus 로고    scopus 로고
    • Unmutated IgV(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia
    • Hamblin T.J., Davis Z., Gardiner A., Oscier D.G., Stevenson F.K. Unmutated IgV(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood 1999, 94:1848-1854.
    • (1999) Blood , vol.94 , pp. 1848-1854
    • Hamblin, T.J.1    Davis, Z.2    Gardiner, A.3    Oscier, D.G.4    Stevenson, F.K.5
  • 36
    • 77949518018 scopus 로고    scopus 로고
    • MicroRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia
    • Han Y.C., Park C.Y., Bhagat G., Zhang J., Wang Y., Fan J.B., et al. microRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia. J. Exp. Med. 2010, 207:475-489.
    • (2010) J. Exp. Med. , vol.207 , pp. 475-489
    • Han, Y.C.1    Park, C.Y.2    Bhagat, G.3    Zhang, J.4    Wang, Y.5    Fan, J.B.6
  • 37
    • 70349750269 scopus 로고    scopus 로고
    • Investigating the targets of MIR-15a and MIR-16-1 in patients with chronic lymphocytic leukemia (CLL)
    • Hanlon K., Rudin C.E., Harries L.W. Investigating the targets of MIR-15a and MIR-16-1 in patients with chronic lymphocytic leukemia (CLL). PLoS ONE 2009, 4:e7169.
    • (2009) PLoS ONE , vol.4
    • Hanlon, K.1    Rudin, C.E.2    Harries, L.W.3
  • 39
    • 34250851115 scopus 로고    scopus 로고
    • A microRNA component of the p53 tumour suppressor network
    • He L., He X., Lim L.P., de Stanchina E., Xuan Z., Liang Y., et al. A microRNA component of the p53 tumour suppressor network. Nature 2007, 447:1130-1134.
    • (2007) Nature , vol.447 , pp. 1130-1134
    • He, L.1    He, X.2    Lim, L.P.3    de Stanchina, E.4    Xuan, Z.5    Liang, Y.6
  • 40
    • 31444446831 scopus 로고    scopus 로고
    • TCL1 shows a regulated expression pattern in chronic lymphocytic leukemia that correlates with molecular subtypes and proliferative state
    • Herling M., Patel K.A., Khalili J., Schlette E., Kobayashi R., Medeiros L.J., et al. TCL1 shows a regulated expression pattern in chronic lymphocytic leukemia that correlates with molecular subtypes and proliferative state. Leukemia 2006, 20:280-285.
    • (2006) Leukemia , vol.20 , pp. 280-285
    • Herling, M.1    Patel, K.A.2    Khalili, J.3    Schlette, E.4    Kobayashi, R.5    Medeiros, L.J.6
  • 41
    • 73649116987 scopus 로고    scopus 로고
    • The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia
    • Klein U., Lia M., Crespo M., Siegel R., Shen Q., Mo T., et al. The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia. Cancer Cell 2010, 17:28-40.
    • (2010) Cancer Cell , vol.17 , pp. 28-40
    • Klein, U.1    Lia, M.2    Crespo, M.3    Siegel, R.4    Shen, Q.5    Mo, T.6
  • 43
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • Lagos-Quintana M., Rauhut R., Lendeckel W., Tuschl T. Identification of novel genes coding for small expressed RNAs. Science 2001, 294:853-858.
    • (2001) Science , vol.294 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 44
    • 0035955366 scopus 로고    scopus 로고
    • An extensive class of small RNAs in Caenorhabditis elegans
    • Lee R.C., Ambros V. An extensive class of small RNAs in Caenorhabditis elegans. Science 2001, 294:862-864.
    • (2001) Science , vol.294 , pp. 862-864
    • Lee, R.C.1    Ambros, V.2
  • 45
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee R.C., Feinbaum R.L., Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993, 75:843-854.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 46
    • 0037009364 scopus 로고    scopus 로고
    • MicroRNA maturation: stepwise processing and subcellular localization
    • Lee Y., Jeon K., Lee J.T., Kim S., Kim V.N. MicroRNA maturation: stepwise processing and subcellular localization. EMBO J. 2002, 21:4663-4670.
    • (2002) EMBO J. , vol.21 , pp. 4663-4670
    • Lee, Y.1    Jeon, K.2    Lee, J.T.3    Kim, S.4    Kim, V.N.5
  • 47
    • 8144225486 scopus 로고    scopus 로고
    • MicroRNA genes are transcribed by RNA polymerase II
    • Lee Y., Kim M., Han J., Yeom K.H., Lee S., Baek S.H., et al. MicroRNA genes are transcribed by RNA polymerase II. EMBO J. 2004, 23:4051-4060.
    • (2004) EMBO J. , vol.23 , pp. 4051-4060
    • Lee, Y.1    Kim, M.2    Han, J.3    Yeom, K.H.4    Lee, S.5    Baek, S.H.6
  • 49
    • 73649096598 scopus 로고    scopus 로고
    • All you need is a Mir-acle: the role of nontranslated RNAs in the suppression of B cell chronic lymphocytic leukemia
    • Lichter P. All you need is a Mir-acle: the role of nontranslated RNAs in the suppression of B cell chronic lymphocytic leukemia. Cancer Cell 2010, 17:3-4.
    • (2010) Cancer Cell , vol.17 , pp. 3-4
    • Lichter, P.1
  • 50
    • 33947224690 scopus 로고    scopus 로고
    • Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression
    • Linsley P.S., Schelter J., Burchard J., Kibukawa M., Martin M.M., Bartz S.R., et al. Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression. Mol. Cell. Biol. 2007, 27:2240-2252.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 2240-2252
    • Linsley, P.S.1    Schelter, J.2    Burchard, J.3    Kibukawa, M.4    Martin, M.M.5    Bartz, S.R.6
  • 51
    • 9844266791 scopus 로고    scopus 로고
    • Cloning of two candidate tumor suppressor genes within a 10kb region on chromosome 13q14, frequently deleted in chronic lymphocytic leukemia
    • Liu Y., Corcoran M., Rasool O., Ivanova G., Ibbotson R., Grander D., et al. Cloning of two candidate tumor suppressor genes within a 10kb region on chromosome 13q14, frequently deleted in chronic lymphocytic leukemia. Oncogene 1997, 15:2463-2473.
    • (1997) Oncogene , vol.15 , pp. 2463-2473
    • Liu, Y.1    Corcoran, M.2    Rasool, O.3    Ivanova, G.4    Ibbotson, R.5    Grander, D.6
  • 52
    • 52649088391 scopus 로고    scopus 로고
    • MiR-16 family induces cell cycle arrest by regulating multiple cell cycle genes
    • Liu Q., Fu H., Sun F., Zhang H., Tie Y., Zhu J., et al. miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes. Nucleic Acids Res. 2008, 36:5391-5404.
    • (2008) Nucleic Acids Res. , vol.36 , pp. 5391-5404
    • Liu, Q.1    Fu, H.2    Sun, F.3    Zhang, H.4    Tie, Y.5    Zhu, J.6
  • 56
    • 39149134593 scopus 로고    scopus 로고
    • Small RNAs analysis in CLL reveals a deregulation of miRNA expression and novel miRNA candidates of putative relevance in CLL pathogenesis
    • Marton S., Garcia M.R., Robello C., Persson H., Trajtenberg F., Pritsch O., et al. Small RNAs analysis in CLL reveals a deregulation of miRNA expression and novel miRNA candidates of putative relevance in CLL pathogenesis. Leukemia 2008, 22:330-338.
    • (2008) Leukemia , vol.22 , pp. 330-338
    • Marton, S.1    Garcia, M.R.2    Robello, C.3    Persson, H.4    Trajtenberg, F.5    Pritsch, O.6
  • 57
    • 0035312968 scopus 로고    scopus 로고
    • Nucleotide sequence, transcription map, and mutation analysis of the 13q14 chromosomal region deleted in B-cell chronic lymphocytic leukemia
    • Migliazza A., Bosch F., Komatsu H., Cayanis E., Martinotti S., Toniato E., et al. Nucleotide sequence, transcription map, and mutation analysis of the 13q14 chromosomal region deleted in B-cell chronic lymphocytic leukemia. Blood 2001, 97:2098-2104.
    • (2001) Blood , vol.97 , pp. 2098-2104
    • Migliazza, A.1    Bosch, F.2    Komatsu, H.3    Cayanis, E.4    Martinotti, S.5    Toniato, E.6
  • 58
    • 34548687035 scopus 로고    scopus 로고
    • Mir-29 regulates Mcl-1 protein expression and apoptosis
    • Mott J.L., Kobayashi S., Bronk S.F., Gores G.J. mir-29 regulates Mcl-1 protein expression and apoptosis. Oncogene 2007, 26:6133-6140.
    • (2007) Oncogene , vol.26 , pp. 6133-6140
    • Mott, J.L.1    Kobayashi, S.2    Bronk, S.F.3    Gores, G.J.4
  • 59
    • 34447107760 scopus 로고    scopus 로고
    • The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila
    • Okamura K., Hagen J.W., Duan H., Tyler D.M., Lai E.C. The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila. Cell 2007, 130:89-100.
    • (2007) Cell , vol.130 , pp. 89-100
    • Okamura, K.1    Hagen, J.W.2    Duan, H.3    Tyler, D.M.4    Lai, E.C.5
  • 60
    • 0030905707 scopus 로고    scopus 로고
    • Differential rates of somatic hypermutation in V(H) genes among subsets of chronic lymphocytic leukemia defined by chromosomal abnormalities
    • Oscier D.G., Thompsett A., Zhu D., Stevenson F.K. Differential rates of somatic hypermutation in V(H) genes among subsets of chronic lymphocytic leukemia defined by chromosomal abnormalities. Blood 1997, 89:4153-4160.
    • (1997) Blood , vol.89 , pp. 4153-4160
    • Oscier, D.G.1    Thompsett, A.2    Zhu, D.3    Stevenson, F.K.4
  • 61
    • 0037103257 scopus 로고    scopus 로고
    • Multivariate analysis of prognostic factors in CLL: clinical stage, IGVH gene mutational status, and loss or mutation of the p53 gene are independent prognostic factors
    • Oscier D.G., Gardiner A.C., Mould S.J., Glide S., Davis Z.A., Ibbotson R.E., et al. Multivariate analysis of prognostic factors in CLL: clinical stage, IGVH gene mutational status, and loss or mutation of the p53 gene are independent prognostic factors. Blood 2002, 100:1177-1184.
    • (2002) Blood , vol.100 , pp. 1177-1184
    • Oscier, D.G.1    Gardiner, A.C.2    Mould, S.J.3    Glide, S.4    Davis, Z.A.5    Ibbotson, R.E.6
  • 62
    • 33846190181 scopus 로고    scopus 로고
    • Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181
    • Pekarsky Y., Santanam U., Cimmino A., Palamarchuk A., Efanov A., Maximov V., et al. Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181. Cancer Res. 2006, 66:11590-11593.
    • (2006) Cancer Res. , vol.66 , pp. 11590-11593
    • Pekarsky, Y.1    Santanam, U.2    Cimmino, A.3    Palamarchuk, A.4    Efanov, A.5    Maximov, V.6
  • 63
    • 33846883741 scopus 로고    scopus 로고
    • Genome-wide analysis of DNA copy number changes and LOH in CLL using high-density SNP arrays
    • Pfeifer D., Pantic M., Skatulla I., Rawluk J., Kreutz C., Martens U.M., et al. Genome-wide analysis of DNA copy number changes and LOH in CLL using high-density SNP arrays. Blood 2007, 109:1202-1210.
    • (2007) Blood , vol.109 , pp. 1202-1210
    • Pfeifer, D.1    Pantic, M.2    Skatulla, I.3    Rawluk, J.4    Kreutz, C.5    Martens, U.M.6
  • 64
    • 67650519133 scopus 로고    scopus 로고
    • The RNA-induced silencing complex: a versatile gene-silencing machine
    • Pratt A.J., MacRae I.J. The RNA-induced silencing complex: a versatile gene-silencing machine. J. Biol. Chem. 2009, 284:17897-17901.
    • (2009) J. Biol. Chem. , vol.284 , pp. 17897-17901
    • Pratt, A.J.1    MacRae, I.J.2
  • 66
    • 4143105617 scopus 로고    scopus 로고
    • ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia
    • Rassenti L.Z., Huynh L., Toy T.L., Chen L., Keating M.J., Gribben J.G., et al. ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia. N. Engl. J. Med. 2004, 351:893-901.
    • (2004) N. Engl. J. Med. , vol.351 , pp. 893-901
    • Rassenti, L.Z.1    Huynh, L.2    Toy, T.L.3    Chen, L.4    Keating, M.J.5    Gribben, J.G.6
  • 67
    • 34250013672 scopus 로고    scopus 로고
    • Abnormal microRNA-16 locus with synteny to human 13q14 linked to CLL in NZB mice
    • Raveche E.S., Salerno E., Scaglione B.J., Manohar V., Abbasi F., Lin Y.C., et al. Abnormal microRNA-16 locus with synteny to human 13q14 linked to CLL in NZB mice. Blood 2007, 109:5079-5086.
    • (2007) Blood , vol.109 , pp. 5079-5086
    • Raveche, E.S.1    Salerno, E.2    Scaglione, B.J.3    Manohar, V.4    Abbasi, F.5    Lin, Y.C.6
  • 71
    • 0035803371 scopus 로고    scopus 로고
    • Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia
    • Rosenwald A., Alizadeh A.A., Widhopf G., Simon R., Davis R.E., Yu X., et al. Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia. J. Exp. Med. 2001, 194:1639-1647.
    • (2001) J. Exp. Med. , vol.194 , pp. 1639-1647
    • Rosenwald, A.1    Alizadeh, A.A.2    Widhopf, G.3    Simon, R.4    Davis, R.E.5    Yu, X.6
  • 72
    • 77956556260 scopus 로고    scopus 로고
    • MicroRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival
    • Rossi S., Shimizu M., Barbarotto E., Nicoloso M.S., Dimitri F., Sampath D., et al. microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival. Blood 2010, 116:945-952.
    • (2010) Blood , vol.116 , pp. 945-952
    • Rossi, S.1    Shimizu, M.2    Barbarotto, E.3    Nicoloso, M.S.4    Dimitri, F.5    Sampath, D.6
  • 73
    • 34447097693 scopus 로고    scopus 로고
    • Intronic microRNA precursors that bypass Drosha processing
    • Ruby J.G., Jan C.H., Bartel D.P. Intronic microRNA precursors that bypass Drosha processing. Nature 2007, 448:83-86.
    • (2007) Nature , vol.448 , pp. 83-86
    • Ruby, J.G.1    Jan, C.H.2    Bartel, D.P.3
  • 75
    • 0028355650 scopus 로고
    • The pathogenesis of chronic lymphocytic leukemia: analysis of the antibody repertoire
    • Schroeder Jr.H.W., Dighiero G. The pathogenesis of chronic lymphocytic leukemia: analysis of the antibody repertoire. Immunol. Today 1994, 15(6):288-294.
    • (1994) Immunol. Today , vol.15 , Issue.6 , pp. 288-294
    • Schroeder, Jr.H.W.1    Dighiero, G.2
  • 76
    • 67149147424 scopus 로고    scopus 로고
    • MicroRNA-29c and microRNA-223 down-regulation has in vivo significance in chronic lymphocytic leukemia and improves disease risk stratification
    • Stamatopoulos B., Meuleman N., Haibe-Kains B., Saussoy P., Van Den Neste E., Michaux L., et al. microRNA-29c and microRNA-223 down-regulation has in vivo significance in chronic lymphocytic leukemia and improves disease risk stratification. Blood 2009, 113:5237-5245.
    • (2009) Blood , vol.113 , pp. 5237-5245
    • Stamatopoulos, B.1    Meuleman, N.2    Haibe-Kains, B.3    Saussoy, P.4    Van Den Neste, E.5    Michaux, L.6
  • 77
    • 34250868124 scopus 로고    scopus 로고
    • Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest
    • Tarasov V., Jung P., Verdoodt B., Lodygin D., Epanchintsev A., Menssen A., et al. Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest. Cell Cycle 2007, 6:1586-1593.
    • (2007) Cell Cycle , vol.6 , pp. 1586-1593
    • Tarasov, V.1    Jung, P.2    Verdoodt, B.3    Lodygin, D.4    Epanchintsev, A.5    Menssen, A.6
  • 78
    • 34848868157 scopus 로고    scopus 로고
    • Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells
    • Tazawa H., Tsuchiya N., Izumiya M., Nakagama H. Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells. Proc. Natl Acad. Sci. USA 2007, 104:15472-15477.
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 15472-15477
    • Tazawa, H.1    Tsuchiya, N.2    Izumiya, M.3    Nakagama, H.4
  • 79
    • 58349119794 scopus 로고    scopus 로고
    • Prognostic markers in chronic lymphocytic leukemia: a comprehensive review
    • Van Bockstaele F., Verhasselt B., Philippe J. Prognostic markers in chronic lymphocytic leukemia: a comprehensive review. Blood Rev. 2009, 23:25-47.
    • (2009) Blood Rev. , vol.23 , pp. 25-47
    • Van Bockstaele, F.1    Verhasselt, B.2    Philippe, J.3
  • 82
    • 65549110908 scopus 로고    scopus 로고
    • MiR-34a as part of the resistance network in chronic lymphocytic leukemia
    • Zenz T., Mohr J., Eldering E., Kater A.P., Buhler A., Kienle D., et al. miR-34a as part of the resistance network in chronic lymphocytic leukemia. Blood 2009, 113:3801-3808.
    • (2009) Blood , vol.113 , pp. 3801-3808
    • Zenz, T.1    Mohr, J.2    Eldering, E.3    Kater, A.P.4    Buhler, A.5    Kienle, D.6
  • 83
    • 77951003346 scopus 로고    scopus 로고
    • MicroRNA expression profile and identification of miR-29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma
    • Zhao J.J., Lin J., Lwin T., Yang H., Guo J., Kong W., et al. microRNA expression profile and identification of miR-29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma. Blood 2010, 115:2630-2639.
    • (2010) Blood , vol.115 , pp. 2630-2639
    • Zhao, J.J.1    Lin, J.2    Lwin, T.3    Yang, H.4    Guo, J.5    Kong, W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.