Telomerase and breast cancer

Breast Cancer Research

Volumn 3, Issue 3, 2001, Pages 146-149

  Herbert, B S ^a   Wright, W E ^a   Shay, J W ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Breast cancer; Inhibitors; Telomeres; Therapy

Indexed keywords

RETINOIC ACID; RNA DIRECTED DNA POLYMERASE INHIBITOR; TAMOXIFEN; TELOMERASE; TELOMERASE INHIBITOR; ZIDOVUDINE;

BREAST CANCER; BREAST CARCINOMA; BREAST DISEASE; CHROMOSOME; CONTROLLED STUDY; DRUG RESISTANCE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; NOTE; PROTEIN EXPRESSION; TELOMERE;

BREAST NEOPLASMS; FEMALE; HUMANS; PROGNOSIS; TELOMERASE; TELOMERE;

EID: 0035033860     PISSN: 14655411     EISSN: None     Source Type: Journal    
DOI: 10.1186/bcr288     Document Type: Note

References (25)

1. Cell proliferation, carcinogenesis and diverse mechanisms of telomerase regulation
2. The two-stage mechanism controlling cellular senescence and immortalization
3. The DNA damage response: Putting checkpoints in perspective
4. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
5. The RNA component of human telomerase
6. Reverse transcriptase motifs in the catalytic subunit of telomerase
7. hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization
8. Telomere maintenance in tumour cells
9. A survey of telomerase activity in human cancer
10. Careful histological confirmation and microdissection reveal telomerase activity in otherwise telomerase-negative breast cancers
11. Telomerase enzyme activity and RNA expression during the multistage pathogenesis of breast carcinoma
12. Quantitation of hTERT gene expression in sporadic breast tumors with a real-time reverse transcription-polymerase chain reaction assay
13. Telomerase is a highly sensitive and specific molecular marker in fine-needle aspirates of breast lesions
14. Telomerase activity as a marker of breast carcinoma in fine-needle aspirated samples
15. Telomerase RNA as a detection marker in the serum of breast cancer patients
16. Telomerase activity correlates with tumor aggressiveness and reflects therapy effect in breast cancer
17. Telomerase activity and lymphovascular invasion in breast cancer
18. Telomerase activity and survival of patients with node-positive breast cancer
19. Genetic changes associated with telomerase activity in breast cancer
20. Telomerase inhibitors
21. Inhibition of cell growth and telomerase activity of breast cancer cells in vitro by 3′-azido-3′-deoxythymidine
22. Reduction of telomeric signals in murine melanoma and human breast cancer cell lines treated with 3′-azido-3′-deoxythymidine
23. Inhibition of cell growth and telomerase activity of breast cancer cells in vitro by retinoic acids
24. Effects of tamoxifen on telomerase activity in breast carcinoma cell lines
25. Effects of chemopreventive and anti-telomerase agents on the spontaneous immortalization of breast epithelial cells